이병완

  #당뇨병#고지혈증#지단백 대사장애#비만#대사증후군#저혈당

학력

1989. 3 ~ 1995. 2 경희대학교 의과대학 학사
2000. 9 ~ 2002. 8 성균관대학교 대학원 내과학 석사
2003. 3 ~ 2005. 8 성균관대학교 대학원 내과학 박사

경력

1995-1996 경희의료원 Intern 수료
1999-2003 삼성서울병원 내과 Resident 수료
2003-2005 삼성서울병원 내과학교실 내분비내과 연구강사
2006-2009 한림대학교 의과대학 내과학교실 조교수
2009-현재 연세대학교 의과대학 내과학교실 심장내과 조/부/정교수

논문

The favorable outcome of human islet transplantation in Korea: experiences of 10 autologous transplantations.
Transplantation 2005;79:1568-1574

A more persistent tolerance to islet allografts through bone marrow transplantation in minimal nonmyleoablative conditioning therapy.
Transplantation Proceedings 2005;37:2266-2269

Heterogeneity of early-onset and ketosis-resistant diabetes in Korea subjects- is it possible to determine cutoff age of early onset type 2 diabetes?
Diabetes Research and Clinical Practice 2005;70:38-45

A white blood cell count in the normal concentration range is independently related to cardiorespiratory fitness in apparently healthy Korean men.
Metabolism 2005;54:1448-1452

Serum gamma-glutamyltransferase within its normal concentration range is related to the presence of diabetes and cardiovascular risk factors.
Diabetic Medicine 2005;22:1134-1140

Effective glycemic control achieved by transplanting non-viral cationic liposome-mediated VEGF-transfected islets in STZ-induced diabetic mice.
Experimental and Molecular Medicine 2005;37(6):513-523

Insulin secretory defect plays a major role in the development of diabetes in patients with distal pancreatectomy.
Metabolism 2006;55:135-141

Continued Suppression of Serum TSH Level May Be Attributed to TSH Receptor Antibody Activity As Well As the Severity of Thyrotoxicosis and the Time to Recovery of Thyroid Hormone in Treated Euthyroid Graves' Patients.
Thyroid. 2006 ;16(12):1251-7.

The comparison of cystatin C and creatinine as an accurate serum marker in the prediction of type 2 diabetic nephropathy.
Diabetes Res Clin Pract. 2007, 78(3):428-34

N-terminal pro-brain natriuretic peptide (NT-proBNP) in Type 2 diabetes with left ventricular dysfunction.
Diabetes Res Clin Pract. 2007 77 Suppl 1:S238-42

Amadori-glycated albumin-induced vascular smooth muscle cell proliferation and expression of inhibitor of apoptosis protein-1 and nerve growth factor-gamma. Biofactors. 2007;31(3-4):145-53

A better yield of islet cell mass from living pancreatic donors compared with cadaveric donors. Clin Transplant. 2007, 21(6):738-43

Changes in total ghrelin within the somatotropic axis in severe burn patients: Comparison of those with inhalation injury and those without inhalation injury Growth Horm IGF Res. 2008: 18(4):291-7

The associations of total and differential white blood cell counts with obesity, hypertension, dyslipidemia and glucose intolerance in a Korean population
J Korean Med Sci. 2008;23(2):193-8

Malignant thymoma associated with myasthenia gravis, Graves' disease, and SIADH (review).
Intern Med. 2008;47(11):1009-12.

Delivery of hypoxia-inducible VEGF gene to rat islets using polyethylenimine. J Drug Target. 2009,17(1):1-9

Delivery of hypoxia-inducible VEGF gene to rat islets using polyethylenimine
Journal Of Drug Targeting 17/1 :1-9,2009

Dose-related cytoprotective effect of alpha-lipoic acid on hydrogen peroxide-induced oxidative stress to pancreatic beta cells
Free Radical Research 43/1 :68-77,2009

A comparison of non-viral vectors for gene delivery to pancreatic β-cells: Delivering a hypoxia-inducible vascular endothelial growth factor gene to rat islets
International Journal Of Molecular Medicine 23/6 :757-762,2009

Enhanced protection of Ins-1 beta cells from apoptosis under hypoxia by delivery of DNA encoding secretion signal peptide-linked exendin-4.
Journal Of Drug Targeting 17/3 :242-248,2009

두 종류의 항체를 보유한 자가면역성 저혈당 1예
임상당뇨병학회지(Clinical Diabetes) 10/2 :123-128,2009

Delayed improvement of insulin secretion after autologous islet transplantation in partially pancreatectomized patients
Metabolism-Clinical and Experimental 58/ :1629-1635,2009

A dual-reporter system for specific tracing of pancreatic -cell lines that non-invasively measures viable in vivo islet cells
BIOTECHNOLOGY LETTERS 32/ :53-57,2010

A Case of Hypoglycemic Brain Injuries with Cortical Laminar Necrosis
JOURNAL OF KOREAN MEDICAL SCIENCE 25/6 :961-965,2010

Dysfunctional pancreatic beta-cells of critical stress play a more prominent role in the development of stress diabetes in critically burned Korean subjects
Metabolism-Clinical and Experimental 59/9 :1307-1315,2010

RAGE ligands induce apoptotic cell death of pancreatic β-cells via oxidative stress
International Journal Of Molecular Medicine 26/6 :813-818,2010

Dietary Monounsaturated Fatty Acids but not Saturated Fatty Acids Preserve the Insulin Signaling Pathway via IRS-1/PI3K in Rat Skeletal Muscle
Lipids 45/ :1109-1116,2010

Fat redistribution preferentially reflects the anti-inflammatory benefits of pioglitazone treatment
METABOLISM-CLINICAL AND EXPERIMENTAL 60/2 :165-172,2011

Up-regulation of hepatic low-density lipoprotein receptor-related protein 1: a possible novel mechanism of antiatherogenic activity of hydroxymethylglutaryl-coenzyme A reductase inhibitor Atorvastatin and hepatic LRP1 expression
METABOLISM-CLINICAL AND EXPERIMENTAL 60/7 :930-940,2011

Predictive characteristics of patients achieving glycaemic control with insulin after sulfonylurea failure
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE 65/10 :1076-1084,2011

Lithospermic acid B protects beta-cells from cytokine-induced apoptosis by alleviating apoptotic pathways and activating anti-apoptotic pathways of Nrf2-HO-1 and Sirt1
TOXICOLOGY AND APPLIED PHARMACOLOGY 252/1 :47-54,2011

Glycated albumin is a useful glycation index for monitoring fluctuating and poorly controlled type 2 diabetic patients
ACTA DIABETOLOGICA 48/2 :167-172,2011

Effect of hypoxia-inducible VEGF gene expression on revascularization and graft function in mouse islet transplantation
TRANSPLANT INTERNATIONAL 24/3 :307-314,2011

Associations Between Cardio-Ankle Vascular Index and Microvascular Complications in Type 2 Diabetes Mellitus Patients
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS 18/4 :328-336,2011

Postprandial Triglyceride Is Associated with Fasting Triglyceride and HOMA-IR in Korean Subjects with Type 2 Diabetes
Diabetes & Metabolism Journal 35/4 :404-410,2011

Dietary Oleate Has Beneficial Effects on Every Step of Non-Alcoholic Fatty Liver Disease Progression in a Methionine- and Choline-Deficient Diet-Fed Animal Model
Diabetes & Metabolism Journal 35/5 :489-496,2011

Korean Red Ginseng (Panax ginseng) Improves Insulin Sensitivity in High Fat Fed Sprague-Dawley Rats
PHYTOTHERAPY RESEARCH 26/ :142-147,2012

Dual pathways of p53 mediated glucolipotoxicity-induced apoptosis of rat cardiomyoblast cell: activation of p53 proapoptosis and inhibition of Nrf2-NQO1 antiapoptosis
METABOLISM-CLINICAL AND EXPERIMENTAL 61/4 :496-503,2012

Guidelines for the use and interpretation of assays for monitoring autophagy
AUTOPHAGY 8/4 :445-544,2012

Potential association between coronary artery disease and the inflammatory biomarker YKL-40 in asymptomatic patients with type 2 diabetes mellitus
CARDIOVASCULAR DIABETOLOGY 11/1 :84-84,2012

Pentoxifylline attenuates methionine- and choline-deficient-diet-induced steatohepatitis by suppressing TNF-α expression and endoplasmic reticulum stress
EXPERIMENTAL DIABETES RESEARCH 2012/ :762565-762565,2012

Glycemic Effects of Once-a-Day Rapid-Acting Insulin Analogue Addition on a Basal Insulin Analogue in Korean Subjects with Poorly Controlled Type 2 Diabetes Mellitus
Diabetes and Metabolism Journal 36/3 :230-236,2012

Dimethyl sulfoxide reduces hepatocellular lipid accumulation through autophagy induction
AUTOPHAGY 8/7 :1085-1097,2012

Higher Morning to Evening Ratio in Total Dose of Twice-Daily Biphasic Insulin Analog Might Be Effective in Achieving Glucose Control in Patients with Poorly Controlled Type 2 Diabetes
DIABETES TECHNOLOGY & THERAPEUTICS 14/6 :508-514,2012

Epicardial adipose tissue thickness is an indicator for coronary artery stenosis in asymptomatic type 2 diabetic patients: Its assessment by cardiac magnetic resonance
CARDIOVASCULAR DIABETOLOGY 11/ :83-83,2012

The Roles of Glycated Albumin as Intermediate Glycation Index and Pathogenic Protein
Diabetes and Metabolism Journal 36/2 :98-107,2012

Latent Autoimmune Diabetes in Adults: Autoimmune Diabetes in Adults with Slowly Progressive β-cell Failure
Diabetes and Metabolism Journal 36/2 :116-119,2012

The effect of rosiglitazone on LRP1 expression and amyloid beta uptake in human brain microvascular endothelial cells: a possible role of a low-dose thiazolidinedione for dementia treatment
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY 15/1 :135-142,2012

Decreased endothelial progenitor cells and increased serum glycated albumin are independently correlated with plaque-forming carotid artery atherosclerosis in type 2 diabetes patients without documented Ischemic disease
CIRCULATION JOURNAL 76/9 :2273-2279,2012

Upregulation of hepatic LRP1 by rosiglitazone: a possible novel mechanism of the beneficial effect of thiazolidinediones on atherogenic dyslipidemia
JOURNAL OF MOLECULAR ENDOCRINOLOGY 49/ :165-174,2012

The ratio of glycated albumin to glycated haemoglobin correlates with insulin secretory function
CLINICAL ENDOCRINOLOGY 77/5 :679-683,2012

Reduction in glycated albumin can predict change in HbA1c: comparison of oral hypoglycaemic agent and insulin treatments
DIABETIC MEDICINE 29/1 :74-79,2012

Serum glycated albumin predicts the progression of carotid arterial atherosclerosis
Atherosclerosis 225/2 :450-455,2012

The Risk of Bladder Cancer in Korean Diabetic Subjects Treated with Pioglitazone
Diabetes and Metabolism Journal 36/5 :371-378,2012

Association between EPCs count and rate of coronary revascularization in asymptomatic type 2 diabetic patients
ACTA DIABETOLOGICA 49/6 :413-420,2012

High prevalence of both anti-insulin and anti-insulin receptor antibodies in Korean patients with insulin autoimmune syndrome
DIABETES RESEARCH AND CLINICAL PRACTICE 98/2 :e12-e15,2012

Human Monoclonal Antibodies against Glucagon Receptor Improve Glucose Homeostasis by Suppression of Hepatic Glucose Output in Diet-Induced Obese Mice
PLOS ONE 7/12 :e50954-e50954,2012

Balsamic Vinegar Improves High Fat-Induced Beta Cell Dysfunction via Beta Cell ABCA1
Diabetes and Metabolism Journal 36/4 :275-279,2012

성장호르몬 분비 뇌하수체 종양의 수술적 완치 후 발견된 지연형 자가면역 당뇨병 1예
대한내분비학회지 27/4 :318-322,2012

The effect of oral prostaglandin analogue on painful diabetic neuropathy: A double-blind, randomized, controlled trial
DIABETES OBESITY & METABOLISM 15/2 :185-188,2013

Enhanced gene transfer to pancreatic islets using glucagon-like peptide-1
TRANSPLANTATION PROCEEDINGS 45/2 :591-596,2013

Variants of the Adiponectin Gene and Diabetic Microvascular Complications in Patients with Type 2 Diabetes
METABOLISM-CLINICAL AND EXPERIMENTAL 62/5 :677-685,2013

Glycated albumin causes pancreatic β-cells dysfunction through autophagy dysfunction
ENDOCRINOLOGY 154/8 :2626-2639,2013

Clinical characteristics and insulin independence of Koreans with new-onset type 2 diabetes presenting with diabetic ketoacidosis
DIABETES-METABOLISM RESEARCH AND REVIEWS 29/6 :507-513,2013

당뇨병성 케톤산증 및 심내막염 환자에 동반된 갈색세포종 1예
The Journal of Korean Diabetes 14/4 :156-161,2013

Efficacy and Safety of Biphasic Insulin Aspart 30/70 in Type 2 Diabetes Suboptimally Controlled on Oral Antidiabetic Therapy in Korea: A Multicenter, Open- Label, Single-Arm Study (Diabetes Metab J 2013;37:117- 24)
Diabetes and Metabolism Journal 37/3 :212-213,2013

Comparison of two creatinine-based equations for predicting decline in renal function in type 2 diabetic patients with nephropathy in a korean population
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY 2013/8489 :1-8,2013

Glycemic Effectiveness of Metformin-Based Dual-Combination Therapies with Sulphonylurea,Pioglitazone, or DPP4-Inhibitor in Drug-Na?ve Korean Type 2 Diabetic Patients
Diabetes and Metabolism Journal 37/6 :465-474,2013

Rosiglitazone attenuates casein-induced hepatic endoplasmic reticulum stress in Sprague-Dawley rats: a novel model of ER stress
ENDOCRINE JOURNAL 60/11 :1231-1240,2013

Transcription factor Snail is a novel regulator of adipocyte differentiation via inhibiting the expression of peroxisome proliferator?activated receptorγ
Cellular and Molecular Life Sciences 70/20 :3959-3971,2013

The hypolipidemic effect of cilostazol can be mediated by regulation of hepatic low-density lipoprotein receptor-related protein 1 (LRP 1) expression
METABOLISM-CLINICAL AND EXPERIMENTAL 63/1 :112-119,2014

Serum cholesterol concentration and prevalence, awareness, treatment, and control of high LDL cholesterol in the Korea National Health and Nutrition Examination Surveys 2008―2010: Beyond the tip of the iceberg
JOURNAL OF THE AMERICAN HEART ASSOCIATION 3/1 :446-,2014

Risk of Bladder Cancer among Patients with Diabetes Treated with a 15 mg Pioglitazone Dose in Korea: A Multi-Center Retrospective Cohort Study
JOURNAL OF KOREAN MEDICAL SCIENCE 29/2 :238-242,2014

The optimal morning: evening ratio in total dose of twice-daily biphasic insulin analogue in poorly controlled Type 2 diabetes: a 24-week multi-centre prospective, randomized controlled, open-labelled clinical study
DIABETIC MEDICINE 31/1 :68-75,2014

The Relationship between BMI and Glycated Albumin to Glycated Hemoglobin (GA/A1c) Ratio According to Glucose Tolerance Status.
PLOS ONE 9/Issue 2 :e89478-,2014

The effect of insulin resistance on postprandial triglycerides in Korean type 2 diabetic patients
ACTA DIABETOLOGICA 51/1 :15-22,2014

Development of an HbA1c-Based Conversion Equation for Estimating Glycated Albumin in a Korean Population with a Wide Range of Glucose Intolerance.
PLOS ONE 9/4 :e95729-,2014

The Effect of DPP-4 Inhibitors on Metabolic Parameters in Patients with Type 2 Diabetes
Diabetes and Metabolism Journal 38/3 :211-219,2014

Optimal glycated albumin cutoff value to diagnose diabetes in Korean adults: A retrospective study based on the oral glucose tolerance test
CLINICA CHIMICA ACTA 437C/- :1-5,2014

Anti-obesity effects of KR-66195, a synthetic DPP-IV inhibitor, in diet-induced obese mice and obese-diabetic ob/ob mice
METABOLISM-CLINICAL AND EXPERIMENTAL 63/6 :793-799,2014

Tolerability, effectiveness and predictive parameters for the therapeutic usefulness of exenatide in obese, Korean patients with type 2 diabetes
JOURNAL OF DIABETES INVESTIGATION 5/5 :554-562,2014

Effect of cilostazol on carotid intima-media thickness in type 2 diabetic patients without cardiovascular event
ENDOCRINE 47/1 :138-145,2014

Inverse Association between Glycated Albumin and Insulin Secretory Function May Explain Higher Levels of Glycated Albumin in Subjects with Longer Duration of Diabetes.
PLOS ONE 9/Issue 9 :e108772-,2014

The glycemic efficacies of insulin analogue regimens according to baseline glycemic status in Korean patients with type 2 diabetes: sub-analysis from the A(1)chieve (R) study
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE 68/11 :1338-1344,2014

Background and Data Configuration Process of a Nationwide Population-Based Study Using the Korean National Health Insurance System
Diabetes and Metabolism Journal 38/5 :395-403,2014

The Glycated Albumin to Glycated Hemoglobin Ratio Might Not Be Associated with Carotid Atherosclerosis in Patients with Type 1 Diabetes
Diabetes and Metabolism Journal 38/6 :456-463,2014

Non-Laboratory-Based Self-Assessment Screening Score for Non-Alcoholic Fatty Liver Disease: Development, Validation and Comparison with Other Scores
PLOS ONE 9/9 :1-10,2014

Postprandial C-peptide to glucose ratio as a predictor of beta-cell function and its usefulness for staged management of type 2 diabetes
JOURNAL OF DIABETES INVESTIGATION 5/5 :517-524,2014

Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway
AUTOPHAGY 11/1 :46-59,2015

Optimal Candidates for the Switch from Glimepiride to Sitagliptin to Reduce Hypoglycemia in Patients with Type 2 Diabetes Mellitus
대한내분비학회지 30/1 :84-91,2015

Glycated albumin and the risk of micro- and macrovascular complications in subjects with Type 1 Diabetes
CARDIOVASCULAR DIABETOLOGY 14/53 :1-8,2015

Comparing kidney outcomes in type 2 diabetes treated with different sulphonylureas in real-life clinical practice
DIABETES & METABOLISM 41/3 :208-215,2015

The Population-Based Risk of Need for Coronary Revascularization According to the Presence of Type 2 Diabetes Mellitus and History of Coronary Heart Disease in the Korean Population
PLOS ONE 10/6 :e0128627-,2015

Use of a Diabetes Self-Assessment Score to Predict Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis
MEDICINE 94/27 :e1103-,2015

Sarcopaenia is associated with NAFLD independently of obesity and insulin resistance: Nationwide surveys (KNHANES 2008?2011)
JOURNAL OF HEPATOLOGY 63/2 :486-493,2015

Undiagnosed diabetes is prevalent in younger adults and associated with a higher risk cardiometabolicprofilecomparedto diagnosed diabetes
AMERICAN HEART JOURNAL 170/4 :760-769,2015

Increased expression of ATP-binding cassette transporter A1 (ABCA1) as a possible mechanism for the protective effect of cilostazol against hepatic steatosis
METABOLISM-CLINICAL AND EXPERIMENTAL 64/11 :1444-1453,2015

Clinical Characteristics of Patients Responding to Once-Daily Basal Insulin Therapy in Korean Subjects with Type 2 Diabetes
Diabetes Therapy 6/4 :547-558,2015

Association Between Heme Oxygenase-1 Promoter Polymorphisms and the Development of Albuminuria in Type 2 Diabetes: A Case?Control Study
MEDICINE 94/43 :e1825-,2015

Glycated Albumin Levels in Patients with Type 2 Diabetes Increase Relative to HbA(1c) with Time
BIOMED RESEARCH INTERNATIONAL 2015/Arti :1-8,2015

1,5-Anhydroglucitol as a Useful Marker for Assessing Short-Term Glycemic Excursions in Type 1 Diabetes
Diabetes and Metabolism Journal 39/2 :164-170,2015

Exogenous administration of DLK1 ameliorates hepatic steatosis and regulates gluconeogenesis via activation of AMPK
INTERNATIONAL JOURNAL OF OBESITY 40/2 :356-365,2016

Sarcopenia Is Associated With Significant Liver Fibrosis Independently of Obesity and Insulin Resistance in Nonalcoholic Fatty Liver Disease: Nationwide Surveys (KNHANES 2008-2011)
HEPATOLOGY 63/3 :776-786,2016

Serum PTHrP predicts weight loss in cancer patients independent of hypercalcemia, inflammation, and tumor burden
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 101/3 :1207-1214,2016

Metformin restores parkin-mediated mitophagy, suppressed by cytosolic p53
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 17/122 :1-14,2016

자가항체 양성인 Ketosis-Prone 당뇨병 1예
The Journal of Korean Diabetes 17/1 :60-66,2016

Association between betatrophin/ANGPTL8 and non-alcoholic fatty liver disease: animal and human studies
SCIENTIFIC REPORTS 6/ :24013-,2016

Effects of Omega-3 Fatty Acid Supplementation on Diabetic Nephropathy Progression in Patients with Diabetes and Hypertriglyceridemia
PLOS ONE 11/5 :e0154683-,2016

Comparison and Validation of 10 Equations Including a Novel Method for Estimation of LDL-cholesterol in a 168,212 Asian Population
MEDICINE 95/14 :e3230-,2016

Urinary N-acetyl-β-D-glucosaminidase, an early marker of diabetic kidney disease, might reflect glucose excursion in patients with type 2 diabetes
MEDICINE 95/27 :e4114-,2016

Efficacy of different dipeptidyl peptidase-4 (DPP-4) inhibitors on metabolic parameters in patients with type 2 diabetes undergoing dialysis
MEDICINE 95/32 :e4543-,2016

Association between dietary acid load and the risk of cardiovascular disease: nationwide surveys (KNHANES 2008-2011)
CARDIOVASCULAR DIABETOLOGY 15/122 :1-14,2016

Sarcopenia is associated with albuminuria independently of hypertension and diabetes: (KNHANES 2008-2011)
METABOLISM-CLINICAL AND EXPERIMENTAL 65/10 :1531-1540,2016

Characteristics Predictive for a Successful Switch from Insulin Analogue Therapy to Oral Hypoglycemic Agents in Patients with Type 2 Diabetes
YONSEI MEDICAL JOURNAL 57/6 :1,395-1,403,2016

Trends in Diabetes Incidence in the Last Decade Based on Korean National Health Insurance Claims Data
대한내분비학회지 31/2 :292-299,2016

Obesity is more closely related with hepatic steatosis and fibrosis measured by transient elastography than metabolic health status
METABOLISM-CLINICAL AND EXPERIMENTAL 66/ :23-31,2017

Lobeglitazone, a Novel Thiazolidinedione, Improves Non-Alcoholic Fatty Liver Disease in Type 2 Diabetes: Its Efficacy and Predictive Factors Related to Responsiveness.
JOURNAL OF KOREAN MEDICAL SCIENCE 32/1 :60-69,2017

Morning Spot Urine Glucose-to-Creatinine Ratios Predict Overnight Urinary Glucose Excretion in Patients With Type 2 Diabetes.
ANNALS OF LABORATORY MEDICINE 37/1 :9-17,2017

Differential association of body mass index on glycemic control in type 1 diabetes
DIABETES-METABOLISM RESEARCH AND REVIEWS 33/e2815 :1-8,2017

The renal tubular damage marker urinary N-acetyl-β-D-glucosaminidase may be more closely associated with early detection of atherosclerosis than the glomerular damage marker albuminuria in patients with type 2 diabetes.
CARDIOVASCULAR DIABETOLOGY 16/16 :1-11,2017

Association between Metformin Use and Risk of Lactic Acidosis or Elevated Lactate Concentration in Type 2 Diabetes
YONSEI MEDICAL JOURNAL 58/2 :312-318,2017

Increase in resting heart rate over 2 years predicts incidence of diabetes: A 10-year prospective study
DIABETES & METABOLISM 43/1 :25-32,2017

Clinical parameters affecting dapagliflozin response in patients with type 2 dabetes
DIABETES & METABOLISM 43/2 :191-194,2017

Anatomic fat depots and cardiovascular risk: a focus on the leg fat using nationwide surveys (KNHANES 2008?2011)
CARDIOVASCULAR DIABETOLOGY 16/154 :1-11,2017

The Relationship between Increases in Morning Spot Urinary Glucose Excretion and Decreases in HbA1C in Patients with Type 2 Diabetes After Taking an SGLT2 Inhibitor: A Retrospective, Longitudinal Study7
DIABETES THERAPY 8/3 :601-609,2017

Effect of gemigliptin on glycaemic variability in patients with type 2 diabetes (STABLE study).
DIABETES OBESITY & METABOLISM 19/6 :892-896,2017

Diabetes self-assessment score and the development of diabetes A 10-year prospective study
MEDICINE 96/23 :e7067-,2017

Comparison between Atorvastatin and Rosuvastatin in Renal Function Decline among Patients with Diabetes
대한내분비학회지 32/2 :274-280,2017

Pre-sarcopenia is associated with renal hyperfiltration independent of obesity or insulin resistance: Nationwide Surveys (KNHANES 2008-2011)
MEDICINE 96/26 :e7165-,2017

Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated mediated activation of autophagy and NLRP3 inflammasome inhibition
AUTOPHAGY 13/10 :1,767-1,781,2017

Effectiveness of Vildagliptin in Clinical Practice: Pooled Analysis of Three Korean Observational Studies (the VICTORY Study)
JOURNAL OF DIABETES RESEARCH 2017/Arti :1-8,2017

Effectiveness and safety of exenatide in Korean patients with type 2 diabetes inadequately controlled with oral hypoglycemic agents: an observational study in a real clinical practice
BMC ENDOCRINE DISORDERS 17/1 :68-77,2017

Insulin Therapy for Adult Patients with Type 2 Diabetes Mellitus: A Position Statement of the Korean Diabetes Association, 2017

Diabetes and Metabolism Journal 41/5 :367-373,2017

Combination Therapy of Oral Hypoglycemic Agents in Patients with Type 2 Diabetes Mellitus
KOREAN JOURNAL OF INTERNAL MEDICINE 32/6 :974-983,2017

Impact of diabetes mellitus and chronic liver disease on the incidence of dementia and all-cause mortality among patients with dementia
MEDICINE 96/47 :-,2017

Association of non-alcoholic steatohepatitis with subclinical myocardial dysfunction in non-cirrhotic patients
JOURNAL OF HEPATOLOGY 68 /4 :764-772,2018

Waist-to-calf circumstance ratio is an independent predictor of hepatic steatosis and fibrosis in patients with type 2 diabetes
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 33/5 :1,082-1,091,2018

Effects of Serum Albumin, Calcium Levels, Cancer Stage and Performance Status on Weight Loss in Parathyroid Hormone-Related Peptide Positive or Negative Patients with Cancer
대한내분비학회지 33/1 :97-104,2018

The Association Between Low 50?g Glucose Challenge Test Values and Adverse Pregnancy Outcomes.
JOURNAL OF WOMENS HEALTH 27/6 :801-807,2018

Comparison of the Effects of Ezetimibe-Statin Combination Therapy on Major Adverse Cardiovascular Events in Patients with and without Diabetes: A Meta-Analysis
대한내분비학회지 33/2 :219-227,2018

Fasting serum amino acids concentration is associated with insulin resistance and pro-inflammatory cytokines
DIABETES RESEARCH AND CLINICAL PRACTICE 140/ :107-117,2018

Glycated Albumin Is a More Useful Glycation Index than HbA1c for Reflecting Renal Tubulopathy in Subjects with Early Diabetic Kidney Disease
Diabetes and Metabolism Journal 42/3 :215-223,2018

Elevated urinary N-Acetyl-β-D-glucosaminidase is associated with high glycoalbumin-To-hemoglobin A1c ratio in type 1 diabetes patients with early diabetic kidney disease
SCIENTIFIC REPORTS 8/1 :6,710-6,718,2018

Differential association of ezetimibe-simvastatin combination with major adverse cardiovascular events in patients with or without diabetes: a retrospective propensity score-matched cohort study
SCIENTIFIC REPORTS 8/1 :11,925-11,932,2018

Elevated N-acetyl-beta-D-glucosaminidase, a urinary tubular damage marker, is a significant predictor of carotid artery atherosclerosis in type 1 diabetes, independent of albuminuria: A cross-sectional study
JOURNAL OF DIABETES AND ITS COMPLICATIONS 32/8 :777-783,2018

Sarcopenia is associated with the risk of significant liver fibrosis in metabolically unhealthy subjects with chronic hepatitis B
ALIMENTARY PHARMACOLOGY & THERAPEUTICS 48/3 :300-312,2018

Effects of lobeglitazone, a novel thiazolidinedione, on adipose tissue remodeling and brown and beige adipose tissue development in db/db mice
INTERNATIONAL JOURNAL OF OBESITY 42/3 :542-551,2018

The Antidiabetic Drug Lobeglitazone Protects Mice From Lipogenesis-Induced Liver Injury via Mechanistic Target of Rapamycin Complex 1 Inhibition
Frontiers in Endocrinology 9/ :539-552,2018

Combining SGLT2 Inhibition With a Thiazolidinedione Additively Attenuate the Very Early Phase of Diabetic Nephropathy Progression in Type 2 Diabetes Mellitus
Frontiers in Endocrinology 9/ :412-422,2018

Protective Effect of Metformin Against Thyroid Cancer Development: A Population-Based Study in Korea
THYROID 28/7 :864-870,2018

Clinical efficacy of the novel thiazolidinedione lobeglitazone in patients with type 2 diabetes
DIABETES & METABOLISM 44/5 :452-455,2018

Relationship Between Circulating Netrin-1 Concentration, Impaired Fasting Glucose, and Newly Diagnosed Type 2 Diabetes
Frontiers in Endocrinology 9/ :691-698,2018

Characteristics of Dapagliflozin Responders: A Longitudinal, Prospective, Nationwide Dapagliflozin Surveillance Study in Korea
DIABETES THERAPY 9/4 :1,689-1,701,2018

A 32-Week Randomized Comparison of Stepwise Insulin Intensification of Biphasic Insulin Aspart (BIAsp 30) Versus Basal?Bolus Therapy in Insulin-Naive Patients with Type 2 Diabetes
DIABETES THERAPY 9/1 :1-11,2018

Sodium-glucose cotransporter 2 inhibitors regulate ketone body metabolism via inter-organ crosstalk
DIABETES OBESITY & METABOLISM 21/4 :801-811,2019

Predictors of the Therapeutic Efficacy and Consideration of the Best Combination Therapy of Sodium-Glucose Co-transporter 2 Inhibitors
Diabetes and Metabolism Journal 43/2 :158-173,2019

Association between nonalbumin proteinuria and renal tubular damage of N-acetyl-β-D-glucosaminidase and its clinical relevance in patients with type 2 diabetes without albuminuria
JOURNAL OF DIABETES AND ITS COMPLICATIONS 33/3 :255-260,2019

Nonalcoholic Fatty Liver Disease and Diabetes: Part II: Treatment
Diabetes and Metabolism Journal 43/2 :127-143,2019

Risk of Incident Dementia According to Metabolic Health and Obesity Status in Late Life: A Population-Based Cohort Study
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 104/7 :2,942-2,952,2019

Nonalcoholic Fatty Liver Disease in Diabetes. Part I: Epidemiology and Diagnosis
Diabetes and Metabolism Journal 43/1 :31-45,2019

Comparison of hepatocellular carcinoma risk between patients treated with glimepiride and gliclazide
DIABETES & METABOLISM 45/1 :83-85,2019

Spontaneous ketonuria and risk of incident diabetes: a 12 year prospective study
DIABETOLOGIA 62/5 :779-788,2019

Effectiveness of Exercise Intervention in Reducing Body Weight and Glycosylated Hemoglobin Levels in Patients with Type 2 Diabetes Mellitus in Korea: A Systematic Review and Meta-Analysis
Diabetes and Metabolism Journal 43/3 / 통권 :302-318,2019

Predictive factors for the development of diabetes in cancer patients treated with phosphatidylinositol 3-kinase inhibitors
CANCER CHEMOTHERAPY AND PHARMACOLOGY 84/2 :405-414,2019

Glucometabolic characteristics and higher vascular complication risk in Korean patients with type 2 diabetes with non-albumin proteinuria
JOURNAL OF DIABETES AND ITS COMPLICATIONS 33/8 :585-591,2019

Current Management of Type 2 Diabetes Mellitus in Primary Care Clinics in Korea
Endocrinology and Metabolism 34/3 :282-290,2019

Effectiveness and Safety of Adding Basal Insulin Glargine in Patients with Type 2 Diabetes Mellitus Exhibiting Inadequate Response to Metformin and DPP-4 Inhibitors with or without Sulfonylurea
Diabetes and Metabolism Journal 43/4 :432-446,2019

Low-dose pioglitazone can ameliorate learning and memory impairment in a mouse model of dementia by increasing LRP1 expression in the hippocampus.
SCIENTIFIC REPORTS 9/ :e4414-,2019

Differential effects of thiazolidinediones and dipeptidyl peptidase-4 inhibitors on insulin resistance and b-cell function in type 2 diabetes mellitus: A propensity score-matched analysis
DIABETES THERAPY 10/1 :149-158,2019

The Effectiveness of Intermittent Fasting to Reduce Body Mass Index and Glucose Metabolism: A Systematic Review and Meta-Analysis
Journal of Clinical Medicine 8/10 :E1645-,2019

Efficacy and Safety of Gemigliptin in Post-Transplant Patients With Type 2 Diabetes Mellitus
TRANSPLANTATION PROCEEDINGS 51/12 :3,444-3,448,2019

저서

당뇨병: 혈관세포 배양기술과 응용 (제2판). 대한당뇨병학회, 골드기획, 2007.7
임상 비만학 (제3판). 대한비만학회, 고려의학, 2008.06
실전 비만학: 성인 & 소아. 대한비만학회, 가본의학, 2008.09

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