배시현

교수, 소화기센터장
    

  #간경변#간암#간염#EBS명의#헬스조선명의

학력

1984~1990 가톨릭대학교 의학 학사
1992~1994 가톨릭대학교 내과학 석사
1994~2000 가톨릭대학교 내과학 박사

경력

2019~2020 은평성모병원 대외협력부원장
2019~2020 은평성모병원 진료협력센터장
2019~2019 은평성모병원 기획홍보실장
2017~2018 서울성모병원 외래진료부장
2015~2017 서울성모병원 소화기내과 분과장
2013~2015 의생명산업연구원 간줄기세포 연구클러스터장
2007~2009 가톨릭중앙의료원 임상시험지원부II부장
2010~2018 서울성모병원 소화기내과 교수
2005~2010 서울성모병원 소화기내과 부교수
2001~2005 강남성모병원 소화기내과 조교수
1999~2001 성빈센트병원 소화기내과 전임강사
1998~1999 강남성모병원 내과 임상강사
1991~1995 강남성모병원 내과 전공의
1990~1991 강남성모병원 인턴

논문

2020 Dec
JOURNAL OF CLINICAL MEDICINE 공동저자
A Real-World Comparative Analysis of Lenvatinib and Sorafenib as a Salvage Therapy for Transarterial Treatments in Unresectable HCC

2020 Nov
Front Oncol 교신저자
Diffusion-Weighted Magnetic Resonance Imaging in Hepatocellular Carcinoma as a Predictor of a Response to Cisplatin-Based Hepatic Arterial Infusion Chemotherapy.

diffusion-weighted magnetic resonance (MR) imaging에서 apparent diffusion coefficient (ADC) ratio가 0.741 미만이면 진행성 간세포암에 HAIC 치료반응이 좋을 것으로 예측할 수 있다.

2020 Nov
FRONTIERS IN ONCOLOGY 교신저자
Diffusion-Weighted Magnetic Resonance Imaging in Hepatocellular Carcinoma as a Predictor of a Response to Cisplatin-Based Hepatic Arterial Infusion Chemotherapy

2020 Nov
INTERNATIONAL JOURNAL OF STEM CELLS 공동저자
Upregulation of C-Reactive Protein by Placenta-Derived Mesenchymal Stem Cells Promotes Angiogenesis in A Rat Model with Cirrhotic Liver

2020 Nov
STEM CELL RESEARCH & THERAPY 공동저자
Enhanced PRL-1 expression in placenta-derived mesenchymal stem cells accelerates hepatic function via mitochondrial dynamics in a cirrhotic rat model

2020 Sep
대한간암학회지(JOURNAL OF LIVER CANCER) 공동저자
Infiltration of T Cells and Programmed Cell Death Ligand 1-expressing Macrophages as a Potential Predictor of Lenvatinib Response in Hepatocellular Carcinoma

2020 Aug
CLINICAL INFECTIOUS DISEASES 공동저자
Association of Prophylactic Anti-Hepatitis B Virus Therapy With Improved Long-term Survival in Patients With Hepatocellular Carcinoma Undergoing Transarterial Therapy

2020 Jul
GUT 공동저자
Comparison of tenofovir and entecavir on the risk of hepatocellular carcinoma and mortality in treatment-naive patients with chronic hepatitis B in Korea: a large-scale, propensity score analysis

2020 Jul
FRONTIERS IN ONCOLOGY 공동저자
Nilotinib-Induced Immune-Mediated Liver Injury: Corticosteroid as a Possible Therapeutic Option

2020 Jul
CLINICAL AND MOLECULAR HEPATOLOGY(舊 THE KOREAN JOURNAL OF HEPATOLOGY, 대한간학회지) 공동저자
Entecavir plus tenofovir vs. lamivudine/telbivudine plus adefovir in chronic hepatitis B patients with prior suboptimal response

2020 Jun
FRONTIERS IN ONCOLOGY 공동저자
Real-World Outcomes of Nivolumab in Patients With Unresectable Hepatocellular Carcinoma in an Endemic Area of Hepatitis B Virus Infection

2020 May
NUTRIENTS 공동저자
Effects of Branched-Chain Amino Acid (BCAA) Supplementation on the Progression of Advanced Liver Disease: A Korean Nationwide, Multicenter, Prospective, Observational, Cohort Study

2020 Apr
LIVER CANCER 공동저자
Gene Signature for Sorafenib Susceptibility in Hepatocellular Carcinoma: Different Approach with a Predictive Biomarker

2020 Mar
GUT AND LIVER 공동저자
Epidemiological and Clinical Characteristics of Hepatitis C Virus Infection in South Korea from 2007 to 2017: A Prospective Multicenter Cohort Study

2020 Mar
JOURNAL FOR IMMUNOTHERAPY OF CANCER 공동저자
EpCAM-high liver cancer stem cells resist natural killer cell-mediated cytotoxicity by upregulating CEACAM1

2020 Mar
대한간암학회지(JOURNAL OF LIVER CANCER) 공동저자
Successful Sequential Therapy Involving Regorafenib after Failure of Sorafenib in a Patient with Recurrent Hepatocellular Carcinoma after Liver Transplantation

2020 Jan
CLINICAL AND MOLECULAR HEPATOLOGY(舊 THE KOREAN JOURNAL OF HEPATOLOGY, 대한간학회지) 공동저자
Clinical characteristics of portal hypertension complicated by gastroesophageal varices in patients with myeloproliferative neoplasms

2019 Dec
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY 공동저자
Long-term Outcomes of Antiviral Therapy in Patients With Advanced Chronic HBV Infection

2019 Dec
HPB 공동저자
Pathologic complete response to chemoembolization improves survival outcomes after curative surgery for hepatocellular carcinoma: predictive factors of response

2019 Oct
Hepatobiliary Surg Nutr 교신저자
Heterogenous responses to nivolumab in a single metastatic nodule in hepatocellular carcinoma: role of salvage surgery.

2019 Oct
GUT 공동저자
Comparison of tenofovir and entecavir on the risk of hepatocellular carcinoma and mortality in treatment-naive patients with chronic hepatitis B in Korea: A large-scale, propensity score analysis

2019 Oct
HEPATOBILIARY SURGERY AND NUTRITION 교신저자
Heterogenous responses to nivolumab in a single metastatic nodule in hepatocellular carcinoma: role of salvage surgery

2019 Oct
DIGESTIVE DISEASES AND SCIENCES 공동저자
Early Hepatitis B Surface Antigen Seroclearance Following Antiviral Treatment in Patients with Reactivation of Resolved Hepatitis B

2019 Sep
CLINICAL INFECTIOUS DISEASES 공동저자
Association of prophylactic anti-HBV therapy with improved long-term survival in patients with hepatocellular carcinoma undergoing transarterial therapy

2019 Sep
대한간암학회지(JOURNAL OF LIVER CANCER) 공동저자
Early Onset Polymorphic Post-transplant Lymphoproliferative Disease Mimicking a Solitary Necrotizing Abscess in a Graft Liver

2019 Jul
DIGESTIVE DISEASES AND SCIENCES 공동저자
Efficacy and Safety of Tenofovir Disoproxil Fumarate in Treatment-Naive Patients with Chronic Hepatitis B in Korea

2019 Jul
ANTICANCER RESEARCH 교신저자
Reduction of Intrahepatic Tumour by Hepatic Arterial Infusion Chemotherapy Prolongs Survival in Hepatocellular Carcinoma

2019 Jun
SCIENTIFIC REPORTS 공동저자
Circulating pro- and anti-angiogenic factors in multi-stage liver disease and hepatocellular carcinoma progression

2019 Jun
FRONTIERS IN IMMUNOLOGY 공동저자
Ex vivo Detection and Characterization of Hepatitis B Virus-Specific CD8(+) T Cells in Patients Considered Immune Tolerant

2019 Jun
JOURNAL OF MEDICAL VIROLOGY 공동저자
Clinical outcomes after the introduction of direct antiviral agents for patients infected with genotype 1b hepatitis C virus depending on the regimens: A multicenter study in Korea

2019 Jun
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY 교신저자
Control of intracranial disease is associated with improved survival in patients with brain metastasis from hepatocellular carcinoma

2019 Apr
JOURNAL OF HEPATOLOGY 공동저자
Sorafenib with or without concurrent transarterial chemoembolization in patients with advanced hepatocellular carcinoma: The phase III STAH trial

2019 Mar
ANTICANCER RESEARCH 교신저자
Reduction of Intrahepatic Tumour by Hepatic Arterial Infusion Chemotherapy Prolongs Survival in Hepatocellular Carcinoma

2018 Dec
CLINICAL AND MOLECULAR HEPATOLOGY(舊 THE KOREAN JOURNAL OF HEPATOLOGY, 대한간학회지) 교신저자
Effect of antiviral therapy in reducing perinatal transmission of hepatitis B virus and maternal outcomes after discontinuing them

2018 Dec
Clin Mol Hepatol 교신저자
Effect of antiviral therapy in reducing perinatal ransmission of hepatitis B virus and maternal outcomes after discontinuing them.
만성활동성 B형간염 임신부에서 출산 10주전 항바이러스제 테노포비어와 텔비부딘 치료로 신생아에 주산기 B형간염의 감염을 예방한다.

2018 Nov
ANNALS OF SURGICAL TREATMENT AND RESEARCH 공동저자
Clinical outcome of 1,000 consecutive cases of liver transplantation: a single center experience

2018 Oct
JOURNAL OF VIRAL HEPATITIS 공동저자
Early development of de novo hepatocellular carcinoma after direct-acting agent therapy: Comparison with pegylated interferon-based therapy in chronic hepatitis C patients

2018 Sep
CANCER CHEMOTHERAPY AND PHARMACOLOGY 교신저자
Randomized, prospective, comparative study on the effects and safety of sorafenib vs. hepatic arterial infusion chemotherapy in patients with advanced hepatocellular carcinoma with portal vein tumor thrombosis

2018 Sep
CLINICAL AND MOLECULAR HEPATOLOGY(舊 THE KOREAN JOURNAL OF HEPATOLOGY, 대한간학회지) 공동저자
Interferon-free treatment for hepatitis C virus infection induces normalization of extrahepatic type I interferon signaling

2018 Jul
KOREAN JOURNAL OF INTERNAL MEDICINE 공동저자
Outcome of donor biliary complications following living donor liver transplantation

2018 Mar
ur J Nucl Med Mol Imaging 교신저자
(18)F-fluorodeoxyglucose uptake of hepatocellular carcinoma as a prognostic predictor in patients with sorafenib treatment.

진행성 간암 치료로 소라페닙으로 치료할 때 (18)F-fluorodeoxyglucose PET 에서 간암의 SUV 값 치료반응 예측에 도움이 된다.

2018 Mar
Cancer Chemother Pharmacol 교신저자
Randomized, prospective, comparative study onthe effects and safety of sorafenib vs. hepatic arterial infusion chemotherapy in patients with advanced hepatocellular carcinoma with portal vein tumor thrombosis.

진행성 간암의 표준치료는 소라페닙이지만, 치료반응이 낮고 부작용이 심하다. 문맥침습 진행성 간암에 간동맥내 항암 주입요법(HAIC)는 치료반응과 안전성이 우수하여 본 연구자는 sorafenib과 HAIC 에 대한 다기관 RCT 연구로 HAIC가 생존기간과 치료반응이 우수함을 증명하였다.

2018 Mar
FRONTIERS IN IMMUNOLOGY 공동저자
Serial Monitoring of Immune Markers Being Represented Regulatory T Cell/T Helper 17 Cell Ratio: Indicating Tolerance for Tapering Immunosuppression after Liver Transplantation

2018 Mar
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 교신저자
18F-fluorodeoxyglucose uptake of hepatocellular carcinoma as a prognostic predictor in patients with sorafenib treatment

2017 Nov
EDITORIAL OFFICE GUT & LIVER, 교신저자
Reactivation of Hepatitis C Virus and Its Clinical Outcomes in Patients Treated with Systemic Chemotherapy or Immunosuppressive Therapy

저서

2013 Dec
가톨릭학원 단독
평화와함께

2013 Dec
생화학분자생물학회 단독
생화학분자생물학회 소식

2013 Jul
liver update 단독
liver update

2013 Apr
Medifo 단독
간 초음파의 이해와 감별 포인트

2008 May
한국조직공학 재생의학회 공동
재생의학총서(II) 성체줄기세포 및 세포 치료제

2019 Jul
군자출판사 공동
(Current principles and clinical practice of) internal medicine : 임상진료지침

보도자료

“암 사망률 2위 간암…40대부터 간 검사 꼭 받으세요”
https://health.chosun.com/site/data/html_dir/2019/05/28/2019052801533.html

[명의에게 묻다] '진행성간암'은 희망없다?…"이젠 완치도 가능"
https://www.yna.co.kr/view/AKR20180206176200017?input=1195m

포스팅

포스팅 내용이 없습니다.

영상자료

완치는 가능한데 발견 어려워…C형 간염 주의보
https://www.yonhapnewstv.co.kr/news/MYH20190803004600038?did=1825m

[EBS 명의 스페셜] 간 건강을 지키는 법
https://www.youtube.com/watch?v=85Bi9ggFYB4

[유투브-내귀에닥터] 알콜성 지방간 피해 술 마시는 방법
https://www.youtube.com/watch?v=-49lF7txZVg

[KBS 교양] 무엇이든물어보세요-지방간은 간 질환의 첫 번째 신호다.
https://www.youtube.com/watch?v=tmlt1jawk2I

발표자료

2020.5.1.-현재 과학기술정보통신부: 전사체 발현양 기반 조합유전자 발굴을 이용한 간 섬유화 제어 면역관련 치료 표적 발굴

2017.4.1-2019.12.31 보건복지부 과제: 간 섬유화 모델에서 중간엽줄기세포의 간세포분화 조절 유전자 발굴 및 항섬유화 기전 규명

2017.3.1.-2020.2.29 미래창조과학부 과제: 간세포암에서 CD44/전환성장인자-베타의 조절을 통한암줄기세포를 억제하는 마이크로RNA 발굴

2015.11.1-2018.7.31 보건복지부과제: Pexa-Vec(펙사벡)의 진행성 간세포암 대상 글로벌 제3상 임상시험 프로세스 관리

2015.8.1.-2017.1.31 보건복지부과제: 전향적, 무작위 배정을 이용한 간의 악성 종양의 고주파열치료 시 자동영상융합기능의 유용성 연구

2015.5.1.-2017.1.31 보건복지부과제: 간경화증 환자에서 간세포암 감시검사로서 6개월 간격 초음파 검사와 1년 간격 비조영 자기공명영상의 비교 연

2013.11.1.-2016.5.31 보건복지부과제: 상시험 글로벌선도센터 컨소시엄의 공개형 지원 인프라 구축

2012.4.1.-2013.5.31. 보건복지부과제: 간암에서의 DLK1, soluble DLK1의 발현과

2008.11.1.-2010.10.31. 보건복지부과제: 비대상성 간경변증 환자에서 자가 골수유래 중간엽줄기세포