조성래

  #성인뇌성마비#근긴장이상증

학력

1990. 3. 1. ~ 1996. 2. 28. 연세대학교 의과대학 학 사 (의 학)
2001. 9. 1. ~ 2005. 2. 28. 연세대학교 의학과 석 사 (재활의학)
2005. 9. 1. ~ 2008. 2. 28. 연세대학교 의학과 박 사 (재활의학)

경력

1996. 3 ~ 1997. 2 연세의대 신촌세브란스 병원 인턴
1997. 3 ~ 2001. 2 연세의대 신촌세브란스 재활의학과 레지던트(전공의)
2001. 3 ~ 2002. 7 연세의대 신촌세브란스 재활의학과 연구강사(전임의)
2002. 8 ~ 2003. 9. 코넬의대 신경과 및 신경과학 Visiting fellow
Cornell University Medical College
Department of Neurology & Neuroscience
2003. 10 ~ 2006. 12 로체스터의대 신경과 Postdoc Research Associate
줄기세포 및 유전자 치료 분과
University of Rochester Medical Center
Department of Neurology
Division of cell and gene therapy
2006. 3 ~ 2012. 2 연세의대 재활의학교실 조교수
2012. 3 ~ 2017.2 연세의대 재활의학교실 부교수
2017. 3 ~ 현재 연세의대 재활의학교실 교수

논문

Parasympathetic Effect Induces Cell Cycle Activation in Upper Limbs of Paraplegic Patients with Spinal Cord Injury
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 20/23 :5,982-5,982,2019

Intrathecal Baclofen Pump Versus Globus Pallidus Interna Deep Brain Stimulation in Adult Patients with Severe Cerebral Palsy
WORLD NEUROSURGERY 126/ :e550-e556,2019

Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report
Annals of Rehabilitation Medicine 43/3 :335-340,2019

Universal Correction of Blood Coagulation Factor VIII in Patient-Derived Induced Pluripotent Stem Cells Using CRISPR/Cas9
STEM CELL REPORTS 12/6 :1,242-1,249,2019

Optogenetic stimulation promotes Schwann cell proliferation, differentiation, and myelination in vitro
SCIENTIFIC REPORTS 9/1 :3,487-3,487,2019

Cell Surface Antigen Display for Neuronal Differentiation-Specific Tracking
BIOMOLECULES & THERAPEUTICS 27/1 :78-84,2019

Effect of Polydeoxyribonucleotide on Angiogenesis and Wound Healing in an In Vitro Model of Osteoarthritis
CELL TRANSPLANTATION 27/11 :1623-1633,2018

Effects of Early Exercise Rehabilitation on Functional Recovery in Patients with Severe Sepsis
YONSEI MEDICAL JOURNAL 59/7 :843-851,2018

An Enriched Environment Ameliorates Oxidative Stress and Olfactory Dysfunction in Parkinson's Disease with alpha-Synucleinopathy
CELL TRANSPLANTATION 27/5 :831-839,2018

Three-dimensional brain-like microenvironments facilitate the direct reprogramming of fibroblasts into therapeutic neurons
Nature biomedical engineering 2/7 :522-539,2018

Environmental Enrichment Upregulates Striatal Synaptic Vesicle-Associated Proteins and Improves Motor Function
FRONTIERS IN NEUROLOGY 9/ :465-478,2018

Relationship Between Swallowing Function and Maximum Phonation Time in Patients With Parkinsonism
Annals of Rehabilitation Medicine 42/3 :425-432,2018

The Schwann Cell as an Active Synaptic Partner
CHEMPHYSCHEM 19/10 :1,123-1,127,2018

The Effect of Environmental Enrichment on Glutathione-Mediated Xenobiotic Metabolism and Antioxidation in Normal Adult Mice
FRONTIERS IN NEUROLOGY 9/425 :1-14,2018

High-Frequency Repetitive Magnetic Stimulation Enhances the Expression of Brain-Derived Neurotrophic Factor Through Activation of Ca2+-Calmodulin-Dependent Protein Kinase II-cAMP-Response Element-Binding Protein Pathway
FRONTIERS IN NEUROLOGY 9/ :285-295,2018

파킨슨병 환자에 대한 말장애지수(Speech Handicap Index)의 적용
Communication Sciences and Disorders 23/1 :160-168,2018

한국판 말장애지수(Speech Handicap Index)의 축소판 개발 및 설암 환자의 적용
Communication Sciences and Disorders 23/1 :218-227,2018

The differential effects of repetitive magnetic stimulation in an in vitro neuronal model of ischemia/reperfusion injury
FRONTIERS IN NEUROLOGY 9/FEB :50-,2018

Anti-inflammatory Effect of DNA polymeric Molecules in a Cell Model of Osteoarthritis
INFLAMMATION 41/2 :677-688,2018

The Applicability of Rhythm-Motor Tasks to a New Dual Task Paradigm for Older Adults
FRONTIERS IN NEUROLOGY 8/ :671-681,2017

An Enriched Environment Ameliorates Oxidative Stress and Olfactory Dysfunction in Parkinson's Disease with ∝-Synucleinopathy
CELL TRANSPLANTATION 27/5 :831-839,2017

Neurobehavioral Assessments in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS e55838/0 :1-6,2017

Analysis of structure-function network decoupling in the brain systems of spastic diplegic cerebral palsy
HUMAN BRAIN MAPPING 38/10 :5,292-5,306,2017

Age-Related Changes in Bimanual Instrument Playing with Rhythmic Cueing
FRONTIERS IN PSYCHOLOGY 8/0 :1,569-1,580,2017

알츠하이머성 치매 환자의 숫자 처리 및 계산 특성
Communication Sciences and Disorders 22/1 :138-145,2017

알츠하이머성 치매의 단어 어휘성 및 규칙성에 따른 실독증
Communication Sciences and Disorders 22/1 :129-137,2017

Outcomes of intrathecal baclofen therapy in patients with cerebral palsy and acquired brain injury.
MEDICINE 96/34 :e7,472-,2017

Patients with non-ambulatory cerebral palsy have higher sclerostin levels and lower bone mineral density than patients with ambulatory cerebral palsy
BONE 103/2017 :302-307,2017

Elucidation of Gene Expression Patterns in the Brain after Spinal Cord Injury
CELL TRANSPLANTATION 26/7 :1286-1300,2017

Effects of pain Scrambler therapy for management of burn scar pruritus: A pilot study
BURNS 43/3 :514-519,2017

Changes in gait patterns induced by rhythmic auditory stimulation for adolescents with acquired brain injury
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 1385/1 :53-62,2016

Clinical outcomes of correcting cervical deformity in cerebral palsy patients
WORLD NEUROSURGERY 96/0 :500-509,2016

Elucidation of Relevant Neuroinflammation Mechanisms Using Gene Expression Profiling in Patients with Amyotrophic Lateral Sclerosis
PLOS ONE 11/11 :e0165290-,2016

In Vivo Expression of Reprogramming Factors Increases Hippocampal Neurogenesis and Synaptic Plasticity in Chronic Hypoxic-Ischemic Brain Injury
NEURAL PLASTICITY 2016/Arti :1-12,2016

Brain Plasticity and Neurorestoration by Environmental Enrichment
Brain & NeuroRehabilitation (뇌신경재활) 9/2 :e2-,2016

In Situ Pluripotency Factor Expression Promotes Functional Recovery From Cerebral Ischemia
MOLECULAR THERAPY 24/9 :1,538-1,549,2016

Effect of extracorporeal shock wave therapy on scar pain in burn patients: A prospective, randomized, single-blind, placebo-controlled study.
MEDICINE 95/32 :e4575-,2016

Astroglial Activation by an Enriched Environment after Transplantation of Mesenchymal Stem Cells Enhances Angiogenesis after Hypoxic-Ischemic Brain Injury
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 17/9 :1-15,2016

The Modulation of Neurotrophin and Epigenetic Regulators: Implication for Astrocyte Proliferation and Neuronal Cell Apoptosis After Spinal Cord Injury
Annals of Rehabilitation Medicine 40/4 :559-567,2016

Differential Expression of Extracellular Matrix and Adhesion Molecules in Fetal-Origin Amniotic Epithelial Cells of Preeclamptic Pregnancy
PLOS ONE 11/5 :e0156038-,2016

Exploring Erythropoietin and G-CSF Combination Therapy in Chronic Stroke Patients
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 17/4 :E463-E476,2016

Induction of neurorestoration from endogenous stem cells
CELL TRANSPLANTATION 25/5 :863-882,2016

Clinical and Pathological Heterogeneity of Korean Patients with CAPN3 Mutations
YONSEI MEDICAL JOURNAL 57/1 :173-179,2016

Environmental enrichment enhances synaptic plasticity by internalization of striatal dopamine transporters
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 36/12 :2122-2133,2016

성인 뇌성마비 환자에서 경막내 바클로펜 주입 후 용량 의존적 보행 양상 변화
Brain & NeuroRehabilitation (뇌신경재활) 8/2 :104-108,2015

Effect of Rhythmic Auditory Stimulation on Hemiplegic Gait Patterns
YONSEI MEDICAL JOURNAL 56/6 :1703-1713,2015

Effects of low- and high-frequency repetitive magnetic stimulation on neuronal cell proliferation and growth factor expression: A preliminary report
NEUROSCIENCE LETTERS 604/0 :167-172,2015

Recapitulation of in vivo-like paracrine signals of human mesenchymal stem cells for functional neuronal differentiation of human neural stem cells in a 3D microfluidic system
BIOMATERIALS 63/28 :177-188,2015

Changes in Hyolaryngeal Movement and Swallowing Function After Neuromuscular Electrical Stimulation in Patients With Dysphagia
Annals of Rehabilitation Medicine 39/2 :199-209,2015

The Effect of Treadmill Exercise on Gait Efficiency During Overground Walking in Adults With Cerebral Palsy
Annals of Rehabilitation Medicine 39/1 :25-31,2015

Adults with spastic cerebral palsy have lower bone mass than those with dyskinetic cerebral palsy
BONE 71/0 :89-93,2015

PSA-NCAM+ Neural Precursor Cells from Human Embryonic Stem Cells Promote Neural Tissue Integrity and Behavioral Performance in A Rat Stroke Model
STEM CELL REVIEWS AND REPORTS 10/6 :761-771,2014

품사 산출 양상에 따른 여성 노년층의 발화 특성
Communication Sciences and Disorders 19/3 :265-273,2014

Short-term effects of erythropoietin on neurodevelopment in infants with cerebral palsy: A pilot study
BRAIN & DEVELOPMENT 36/9 :764-769,2014

Targeted inversion and reversion of the blood coagulation factor 8 gene in human iPS cells using TALENs
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111/25 :9253-9258,2014

Two-Year Outcomes of Deep Brain Stimulation in Adults With Cerebral Palsy
Annals of Rehabilitation Medicine 38/2 :209-217,2014

GABAergic neuronal differentiation induced by brain-derived neurotrophic factor in human mesenchymal stem cells
ANIMAL CELLS AND SYSTEMS 18/1 :17-24,2014

Hand rehabilitation using MIDI keyboard playing in adolescents with brain damage: A preliminary study
NEUROREHABILITATION 34/1 :147-155,2014

Time-dependent effect of combination therapy with erythropoietin and granulocyte colony-stimulating factor in a mouse model of hypoxic-ischemic brain injury
NEUROSCIENCE BULLETIN 30/ :107-117,2014

Gene Expression Profiling in Parkinson’s Disease
Vascular Neurology 5/1 :27-30,2013

Angiogenesis Induced by Physical Exercise in Adult Brain
Vascular Neurology 5/1 :12-15,2013

Neurogenic Effect of Repetitive Transcranial Magnetic Stimulation in Adult Brain
Vascular Neurology 5/1 :16-19,2013

Finger exercise with keyboard playing in adults with cerebral palsy: A preliminary study
Journal of Exercise Rehabilitation 9/4 :420-425,2013

Therapeutic effects of repetitive transcranial magnetic stimulation in an animal model of Parkinson's disease
BRAIN RESEARCH 1537/0 :290-302,2013

Balance and Coordination Training for Brain Disorders
Brain & NeuroRehabilitation (뇌신경재활) 6/2 :68-72,2013

Swallowing-Quality of Life (SWAL-QOL) 척도의 한국어판 번안
Communication Sciences and Disorders 18/3 :341-347,2013

Fibroblast Growth Factor-2 Induced by Enriched Environment Enhances Angiogenesis and Motor Function in Chronic Hypoxic-Ischemic Brain Injury
PLOS ONE 8/9 :-,2013

Epigenetic regulation in the brain after spinal cord injury: A comparative study
JOURNAL OF KOREAN NEUROSURGICAL SOCIETY 53/6 :337-341,2013

Environmental Enrichment Synergistically Improves Functional Recovery by Transplanted Adipose Stem Cells in Chronic Hypoxic-Ischemic Brain Injury
CELL TRANSPLANTATION 22/9 :1553-1568,2013

Acoustic characteristics of vowel sounds in patients with Parkinson disease
NEUROREHABILITATION 32/3 :649-654,2013

Alteration of Synaptic Activity-Regulating Genes Underlying Functional Improvement by Long-term Exposure to an Enriched Environment in the Adult Brain
NEUROREHABILITATION AND NEURAL REPAIR 27/6 :561-574,2013

Role of Astrocytes for Neurorestoration
Vascular Neurology 4/ :2-5,2012

Immunomodulation by Stem Cells and Hematopoietic Growth Factors for Neurorestoration
Vascular Neurology 4/ :6-9,2012

Factors Affecting Bone Mineral Density in Adults with Cerebral Palsy
대한재활의학회지(Annals of Rehabilitation Medicine) 36/6 :770-775,2012

Diseases in a Dish: The Challenge of Disease Models Using Induced Pleuripotent Stem Cells
Vascular Neurology 4/ :1-1,2012

Differential effects of rhythmic auditory stimulation and neurodevelopmental treatment/Bobath on gait patterns in adults with cerebral palsy
CLINICAL REHABILITATION 26/10 :904-904,2012

Neurorestoration Induced by Mesenchymal Stem Cells: Potential Therapeutic Mechanisms for Clinical Trials
YONSEI MEDICAL JOURNAL 53/6 :1059-1067,2012

Highly pure and expandable PSA-NCAM-positive neural precursors from human ESC and iPSC-derived neural rosettes
PLOS ONE 7/7 :e39715-e39715,2012

The Effect of Bilateral Globus Pallidus Internus Deep Brain Stimulation plus Ventralis Oralis Thalamotomy on Patients with Cerebral Palsy
STEREOTACTIC AND FUNCTIONAL NEUROSURGERY 90/5 :292-299,2012

말 산출에서 피질하 구조의 역할
대한신경과학회지 30/1 :1-9,2012

Effects of Scutellaria baicalensis on neurogenesis in the hippocampal dentate gyrus and on spatial memory of adult rats
NEURAL REGENERATION RESEARCH 6/27 :2085-2093,2011

Early Immunomodulation by Intravenously Transplanted Mesenchymal Stem Cells Promotes Functional Recovery in Spinal Cord Injured Rats
Cell Medicine, Part B of Cell Transplantation 2/ :55-67,2011

Changes in gait patterns with rhythmic auditory stimulation in adults with cerebral palsy
NEUROREHABILITATION 29/3 :233-241,2011

Surrogate reporters for enrichment of cells with nuclease-induced mutations
NATURE METHODS 8/11 :941-944,2011

Brain Plasticity Induced by Enriched Environment
Vascular Neurology 3/ :27-29,2011

Imminent Fracture in a Patient with Atypical Femoral Fracture after Prolonged Use of Bisphosphonates
Vascular Neurology 3/ :42-44,2011

Generation of Patient and Disease Specific Induced Pleuripotent Stem Cells
Vascular Neurology 3/3 :20-22,2011

Therapeutic Effects of Erythropoietin and Granulocyte Colony-Stimulating Factor in Stroke
Vascular Neurology 3/ :23-26,2011

Combined Therapy of Orthopedic Surgery after Deep Brain Stimulation in Cerebral Palsy Mixed Type
Annals of Rehabilitation Medicine 35/ :589-593,2011

요통의 비수술적 치료
Medical Review 5/3 :23-28,2011

운동감소형 마비말장애의 조음교대운동 특성: 속도 및 규칙성
언어청각장애연구 16/1 :74-82,2011

Attenuation of Spinal Curvature and Pelvic Obliquity by Body Shape Molded Inner System in Cerebral Palsy with Non-Fixed Scoliosis
대한재활의학회지 35/2 :259-264,2011

Induction of Striatal Regeneration Delays Motor Deterioration in a Mouse Model of Huntington’s Disease
TISSUE ENGINEERING AND REGENERATIVE MEDICINE 8/2 :164-172,2011

신경퇴행성 질환 동물 모델
Brain & NeuroRehabilitation 4/1 :30-34,2011

Motor pathway injury in patients with periventricular leucomalacia and spastic diplegia
BRAIN 134/4 :1199-1210,2011

Effects of constraint-induced movement therapy on neurogenesis and functional recovery after early hypoxic-ischemic injury in mice
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY 53/4 :327-333,2011

Gait Training and Rhythm: A Review of Rhythmic Auditory Stimulation
Vascular Neurology 2/1 :4-6,2010

외상성 뇌손상 환자에서 리듬청각자극을 통한 보행훈련 효과
Vascular Neurology 2/1 :37-41,2010

뇌성마비 및 유전성 경직성 하지마비로 오진된 도파반응성 근긴장 이상증 2예 -증례 보고-
Journal Of The Korean Academy Of Rehabilitation Medicine(대한재활의학회지) 34/5 :583-586,2010

INDUCTION OF STRIATAL NEUROGENESIS ENHANCES FUNCTIONAL RECOVERY IN AN ADULT ANIMAL MODEL OF NEONATAL HYPOXIC-ISCHEMIC BRAIN INJURY
NEUROSCIENCE 169/1 :259-268,2010

리듬청각자극을 사용한 편측 경직성 뇌성마비 성인의 보행훈련 사례 연구
한국운동재활학회지 6/1 :119-130,2010

Feasibility of sonography for intra-articular injections in the knee through a medial patellar portal.
Journal Of Ultrasound In Medicine 28/ :1465-1470,2009

Functional Recovery After the Transplantation of Neurally Differentiated Mesenchymal Stem Cells Derived From Bone Barrow in a Rat Model of Spinal Cord Injury
Cell Transplantation 18/12 :1359-1368,2009

뇌졸중에서 Erythropoietin 치료 기전 및 효과
vascular neurology 1/ :24-26,2009

상하지 사이클 운동에 의한 에너지 소모량 및 보행 능력 비교
Journal Of The Korean Academy Of Rehabilitation Medicine(대한재활의학회지) 33/6 :584-590,2009

자발 운동 및 부유 환경 조성에 의한 선조체 내 신경세포 생성 유도
대한재활의학회지(Journal Of The Korean Academy Of Rehabilitation Medicine) 32/6 :632-636,2008

말ㆍ언어 장애 아동에서 언어지수와 지능 및 사회지수의 관계
대한재활의학회지(Journal Of The Korean Academy Of Rehabilitation Medicine) 32/2 :129-134,2008

급성기 허혈성 뇌손상 동물 모델에서 재활 치료
Journal of Neurocritical Care 1/1 :27-30,2008

Neurally induced umbilical cord blood cells modestly repair injured spinal cords
Neuroreport 19/ :1259-1263,2008

헌팅톤 병 동물 모델에서 치료효과 판정을 위한 운동기능 평가
대한재활의학회지(Journal Of The Korean Academy Of Rehabilitation Medicine) 31/5 :503-511,2007

남성 척수손상인에서 슈도에페드린 복용이 정액의 질에 미치는 효과
대한재활의학회지(Journal Of The Korean Academy Of Rehabilitation Medicine) 31/2 :182-187,2007

Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease
JOURNAL OF CLINICAL INVESTIGATION 117/10 :2889-2902,2007

Colonic transit time and constipation in children with spastic cerebral palsy
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION 85/ :453-456,2004

Characteristics of psychosexual functioning in adults with cerebral palsy
CLINICAL REHABILITATION 18/4 :423-429,2004

성인 뇌성마비에서 보행시 에너지 소모량 평가
대한재활의학회지(Journal Of The Korean Academy Of Rehabilitation Medicine) 28/6 :537-541,2004

뇌성마비 성인의 방광기능 평가
대한재활의학회지 27/2 :198-203,2003

뇌성마비 성인의 대장운동 기능 및 영양섭취 상태 평가
대한재활의학회지 27/2 :192-197,2003

뇌성마비 성인의 정신적 건강 상태
대한재활의학회지 27/2 :-,2003

The characteristics of sit-to-stand transfer in young children with spastic cerebral palsy based on kinematic and kinetic data
Gait Posture 17/1 :43-49,2003

선천성 근섬유 불균형 근병증
대한재활의학회지(Journal Of The Korean Academy Of Rehabilitation Medicine) 26/4 :485-488,2002

Assessment of Autonomic Nervous System with Analysis of Heart Rate Variability in Children with Spastic Cerebral Palsy
YONSEI MEDICAL JOURNAL 43/1 :65-72,2002

성인 뇌성마비의 성기능 평가
대한재활의학회지(Journal Of The Korean Academy Of Rehabilitation Medicine) 26/5 :519-525,2002

스트레스 적외선 체열 촬영을 통한 정상인의 교감신경계 혈관운동성 반응
대한재활의학회지(Journal Of The Korean Academy Of Rehabilitation Medicine) 26/2 :223-227,2002

반사성 교감신경성 이영양증에서 스트레스 적외선 체열 검사의 유용성
대한재활의학회지(Journal Of The Korean Academy Of Rehabilitation Medicine) 26/6 :687-692,2002

경직성 뇌성마비 환아에서 대장운동 기능 및 영양섭취 상태의 평가
대한재활의학회지(Journal Of The Korean Academy Of Rehabilitation Medicine) 26/1 :19-25,2002

성인 불수의 운동형 뇌성마비에서 만성 통증과 사회심리적 기능
대한재활의학회지(Journal Of The Korean Academy Of Rehabilitation Medicine) 26/4 :391-397,2002

남성 척수손상 장애인에서 사정유도 자극을 이용한 인공수정 및 출산 사례
대한재활의학회지 25/1 :181-185,2001

남성 척수손상 장애인에서 Derogatis 성기능검사(DSFI)를 통한 성기능 평가
대한재활의학회지(Journal Of The Korean Academy Of Rehabilitation Medicine) 24/3 :469-476,2000

척수손상 환자에서의 심박변동 분석에 의한 자율신경기능 평가
대한재활의학회지(Journal Of The Korean Academy Of Rehabilitation Medicine) 24/1 :35-41,2000

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