심규원

  #소아신경외과#뇌종양외과

학력

1997 연세대학교 의과대학 졸업
2002 연세대학교 대학원 석사 취득
2010 연세대학교 대학원 박사 취득

경력

2005.5.-2008.2. 연세대학교 의과대학 신경외과학교실 연구강사(소아신경외과 ,뇌종양외과)
2008.3.-2009.2. 연세대학교 의과대학 신경외과학교실 전임강사
2009.3.-2019.2. 연세대학교 의과대학 신경외과학교실 조교수
2019.3.-현재 연세대학교 의과대학 신경외과학교실 교수

논문

Treatment modality for intractable epilepsy in hypothalamic hamartoma/Neurosurgery/2008
Prediction of prognosis in medulloblastoma using immunohistochemical analysis and tissue microarray/Journal of Neurosurgery/2008
Simultaneous endoscopic third ventriculostomy and ventriculoperitoneal shunt for infantile hydrocephalus/Child’s Nervous system/2007
Pineal cavernous malformations; report of two cases/Yonsei Medical Journal/2005
소아에서 두개강 내 해면상 혈관종의 수술적 치료/대한소아신경외과학회지/2006
두개강내 수막종에 대한 감마나이프 방사선수술
대한신경외과학회지(JOURNAL OF KOREAN NEUROSURGICAL SOCIETY) 30/11 :1263-1270,2001
Pineal cavernous malformations: Report of two cases
YONSEI MEDICAL JOURNAL 46/ :851-858,2005
Congenital cavernous sinus cystic teratoma
YONSEI MEDICAL JOURNAL 48/4 :704-710,2007
직장 항문 기형 환자에서 동반하는 척추 이형성
대한소아신경외과학회지 4/1 :29-32,2007
지주막 낭종에서 수술적 치료 방법 선택
대한소아신경외과학회지 4/1 :15-22,2007
악성으로 변환하여 재발한 성숙 과오종
대한소아신경외과학회지 4/1 :83-88,2007
Treatment failure in intracranial primary germinomas
CHILDS NERVOUS SYSTEM 23/ :1155-1161,2007
Distraction vs remodeling surgery for craniosynostosis
CHILDS NERVOUS SYSTEM 23/ :201-206,2007
Long term magnetic Resonance Angiography follow-up in moyamoya disease
대한뇌혈관외과학회지(Korean Journal of Cerebrovascular Surgery) 9/3 :188-192,2007
악성 뇌종양에서 Gliadel Wafer의 효용성; 예비 보고
대한뇌종양학회지(JOURNAL OF KOREAN BRAIN TUMOR SOCIETY) 6/2 :80-88,2007
Mixed or metachronous germ-cell tumor?
CHILDS NERVOUS SYSTEM 23/ :713-718,2007
Simultaneous endoscopic third ventriculostomy and ventriculoperitoneal shunt for infantile hydrocephalus
Childs Nervous System 24/ :443-451,2008
Management of intracranial cavernous malformation in pediatric patients
Childs Nervous System 24/3 :321-327,2008
Factors contributing to resectability and seizure outcomes in 44 patients with ganglioglioma
Clinical Neurology And Neurosurgery 110/ :667-673,2008
Prediction of prognosis in children with medulloblastoma by using immunohistochemical analysis and tissue microarray
Journal of Neurosurgery-Pediatrics 1/ :196-205,2008

Treatment modality for intractable epilepsy in hypothalamic hamartomatous lesions
Neurosurgery 62/4 :847-856,2008

Changing the paradigm of 1-stage total callosotomy for the treatment of pediatric generalized epilepsy
Journal of Neurosurgery-Pediatrics 2/ :29-36,2008

난치성 간질 환자에서 뇌량 절제술
대한소아신경외과학회지(The Korean Journal of Pediatric Neurosurgery) 5/1 :1-8,2008

속질모세포종 치료후 발생한 2차 악성 종양(급성 골수백혈병): 증례 보고
대한소아신경외과학회지(The Korean Journal of Pediatric Neurosurgery) 5/1 :37-42,2008

피질 이형성증과 미세이형성의 영상 의학적, 전기생리적 및 임상적 차이
대한소아신경외과학회지(The Korean Journal of Pediatric Neurosurgery) 5/1 :30-36,2008

뇌종자세포종(Intracranial Germinoma)의 치료에 있어 방사선 단독치료와 방사선 및 약물 병용 치료군에서의 방사선 용량 비교
임상소아혈액종양(Korean Journal of Pediatric Hematology-Oncology) 15/2 :118-,2008

Treatment and outcomes of primary intracranial teratoma
Childs Nervous System 25/12 :1581-1587,2009

Factors contributing improvement of syringomyelia and surgical outcome in type i Chiari malformation
Childs Nervous System 25/4 :453-459,2009

Insular epilepsy surgery under neuronavigation guidance using depth electrode
Childs Nervous System 25/5 :591-597,2009

Neurocognitive and psychological profiles in pediatric arachnoid cyst
Childs Nervous System 25/9 :1071-1076,2009

The history of ependymoma management
Childs Nervous System 25/10 :1167-1183,2009

Endoscopic disconnection of hypothalamic astrocytoma causing gelastic epilepsy: Case report
Journal of Neurosurgery-Pediatrics 4/2 :151-155,2009

Treatment option for arachnoid cysts
Childs Nervous System 25/0 :1459-1466,2009

측뇌실 삼각의 해면상 혈관종: 증례보고
대한소아신경외과학회지 6/1,2 :27-31,2009

Resective Pediatric Epilepsy Surgery in Lennox-Gastaut Syndrome
Pediatrics 125/1 :E58-E66,2010

Spinal dysraphism with anorectal malformation: lumbosacral magnetic resonance imaging evaluation of 120 patients
Journal Of Pediatric Surgery 45/4 :769-776,2010

What should we do with a discontinued shunt?
CHILDS NERVOUS SYSTEM 26/ :791-796,2010

고형 종괴 없는 파종성 일차성 역형성 뇌수막종
대한뇌종양학회지(JOURNAL OF KOREAN BRAIN TUMOR SOCIETY) 9/2 :103-107,2010

두개강 내 원발성 생식세포종 대한 소아뇌종양학회 치료 프로토콜 치료 경험
대한소아신경외과학회지 7/1 :6-19,2010

외측두엽 간질의 수술적 결과
대한소아신경외과학회지 7/1 :31-40,2010

Adjustable and Gravitation-Assisted Valve: ProGAVⓡ의 신뢰도와 유용성에 대한 후향적 임상 분석 연구
대한소아신경외과학회지 7/1 :41-46,2010

기저핵 및 시상에 발생하는 배아종: 진단, 치료 및 예후
대한소아신경외과학회지 7/1 :84-89,2010

59-YEAR OLD FEMALE WITH SUPRASELLAR MASS
Brain Pathology 20/1 :257-260,2010

Surgical treatment of hypothalamic hamartoma
Neurology Asia 15/suppl :15-20,2010

17-YEAR-OLD GIRL WITH HEADACHE AND COMPLEX PARTIAL SEIZURE
Brain Pathology 20/6 :1111-1114,2010

외과적 뇌질환을 가진 학령기 아동의 수술 전 정서적 불안정감과 어머니의 양육스트레스에 관한 예비연구
소아 청소년 정신의학 21/3 :168-173,2010

신경외과적 뇌질환을 지닌 영유아 어머니의 양육 스트레스
영유아아동정신건강연구 3/1 :1-16,2010

Neuroimaging in identifying focal cortical dysplasia and prognostic factors in pediatric and adolescent epilepsy surgery
EPILEPSIA 52/4 :722-727,2011

Tuberculous Encephalopathy without Meningitis: Pathology and Brain MRI Findings
EUROPEAN NEUROLOGY 65/3 :156-159,2011

Focal time-to-peak changes on perfusion MRI in children with Moyamoya disease: Correlation with conventional angiography
ACTA RADIOLOGICA 52/6 :675-679,2011

Changes in integrity of normal-appearing white matter in patients with moyamoya disease: A diffusion tensor imaging study
AMERICAN JOURNAL OF NEURORADIOLOGY 32/10 :1893-1898,2011

Natural history and progression factors of unilateral moyamoya disease in pediatric patients
CHILDS NERVOUS SYSTEM 27/8 :1281-1287,2011

A Multimodal Approach Including Craniospinal Irradiation Improves the Treatment Outcome of High-Risk Intracranial Nongerminomatous Germ Cell Tumors
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 84/3 :625-631,2012

Joubert Syndrome: 2 Cases and Literature Review
대한소아신경외과학회지 9/1 :18-22,2012

외상성 두부 손상 아동의 인지기능 특성
대한소아신경외과학회지 9/1 :1-6,2012

Nuclear localization of folate receptor alpha: a new role as a transcription factor
SCIENTIFIC REPORTS 2/980 :1-7,2012

Validation of tumor markers in central nervous system germ cell tumors by real-time reverse transcriptase polymerase chain reaction using formalin-fixed paraffin-embedded tissues
MOLECULAR MEDICINE REPORTS 7/1 :337-341,2013

Treatment strategy for intracranial primary pure germinoma
CHILDS NERVOUS SYSTEM 29/2 :239-248,2013

Transventricular Endoscopic Fenestration of Intrasellar Arachnoid Cyst
NEUROSURGERY 72/4 :520-528,2013

Isolation of mesenchymal stem-like cells in meningioma specimens
INTERNATIONAL JOURNAL OF ONCOLOGY 43/4 :1260-1268,2013

Epigenetic modification after inhibition of IGF-1R signaling in human central nervous system atypical teratoid rhabdoid tumor (AT/RT)
CHILDS NERVOUS SYSTEM 29/8 :1245-1251,2013

The Usefulness of Diffusion Tensor Image-integrated Neuronavigation in Pediatric Epilepsy Surgery
대한소아신경외과학회지 10/1 :15-21,2013

Primary Spinal Cord Oligodendroglioma in a Pediatric Patient
대한소아신경외과학회지 10/1 :22-24,2013

Outcomes of epilepsy surgery in childhood-onset epileptic encephalopathy
BRAIN & DEVELOPMENT 36/6 :496-504,2014

The Manufacture of Custom Made 3D Titanium Implant for Skull Reconstruction
Journal of International Society for Simulation Surgery 1/1 :13-15,2014

A critical role of noggin in developing folate-nonresponsive NTD in Fkbp8?/? embryos
CHILDS NERVOUS SYSTEM 30/8 :1,343-1,353,2014

Neurocognitive function in children after anterior temporal lobectomy with amygdalohippocampectomy
PEDIATRIC NEUROLOGY 52/1 :88-93,2015

How would we deal with hypothalamic hamartomas?
World Journal of Surgical Procedures 5/1 :65-74,2015

Cognitive Outcome of Pediatric Moyamoya Disease
JOURNAL OF KOREAN NEUROSURGICAL SOCIETY 57/6 :440-444,2015

Three-dimensional analysis of cranial and facial asymmetry after helmet therapy for positional plagiocephaly
CHILDS NERVOUS SYSTEM 31/7 :1113-1120,2015

Patterns of Failure Following Multimodal Treatment for Medulloblastoma: Long-Term Follow-up Results at a Single Institution
CANCER RESEARCH AND TREATMENT 47/4 :879-888,2015

Expansion and compression distraction osteogenesis based on volumetric and neurodevelopmental analysis in sagittal craniosynostosis
CHILDS NERVOUS SYSTEM 31/11 :2081-2089,2015

Skull Reconstruction with Custom Made Three-Dimensional Titanium Implant
Archives of Craniofacial Surgery 16/1 :11-16,2015

CD133 and DNA-PK regulate MDR1 via the PI3K- or Akt-NF-κB pathway in multidrug-resistant glioblastoma cells in vitro
ONCOGENE 2015/35 :241-250,2016

Computer-assisted shape descriptors for skull morphology in craniosynostosis
CHILDS NERVOUS SYSTEM 32/10 :511-517,2016

Treatment Outcome and Prognostic Molecular Markers of Supratentorial Primitive Neuroectodermal Tumors
PLOS ONE 11/4 :e0153443-,2016

Neurodevelopmental Problems in Non-Syndromic Craniosynostosis
JOURNAL OF KOREAN NEUROSURGICAL SOCIETY 59/3 :242-246,2016

Cranioplasty Enhanced by Three-Dimensional Printing: Custom-Made Three-Dimensional-Printed Titanium Implants for Skull Defects
JOURNAL OF CRANIOFACIAL SURGERY 27/4 :943-949,2016

중추신경계 생식세포종양의 최근 치료 경향
Clinical Pediatric Hematology-Oncology 23/1 :17-27,2016

Multiple Spontaneous Intracerebral Hematoma without Presenting Risk Factors
Journal of Cerebrovascular and Endovascular Neurosurgery 18/3 :286-290,2016
Correction of Sagittal Craniosynostosis Using Distraction Osteogenesis Based on Strategic Categorization
PLASTIC AND RECONSTRUCTIVE SURGERY 139/1 :157-169,2017

Sacral Reconstruction with a 3D-Printed Implant after Hemisacrectomy in a Patient with Sacral Osteosarcoma: 1-Year Follow-Up Result
YONSEI MEDICAL JOURNAL 58/2 :453-457,2017

Endoscopic Treatment of Hypothalamic Hamartomas
JOURNAL OF KOREAN NEUROSURGICAL SOCIETY 60/3 :294-300,2017

Neuroendoscopy : Current and Future Perspectives
JOURNAL OF KOREAN NEUROSURGICAL SOCIETY 60/3 :332-336,2017

Exploring for the optimal structural design for the 3D-printing technology for cranial reconstruction: a biomechanical and histological study comparison of solid vs. porous structure
CHILDS NERVOUS SYSTEM 33/9 :1553-1562,2017

The Unnecessity of Positron Emission Tomography Computed Tomography in the Etiologic Evaluation of Neurodevelopmental Delay in Craniosynostosis Patients
Archives of Craniofacial Surgery 18/1 :21-24,2017

Altered cerebrospinal fluid dynamics in neurofibromatosis type l: severe arachnoid thickening in patients with neurofibromatosis type 1 may cause abnormal CSF dynamic.
CHILDS NERVOUS SYSTEM 33/5 :767-775,2017

Efficacy of endoscopic third ventriculostomy in old aged patients with normal pressure hydrocephalus.
NEUROLOGIA I NEUROCHIRURGIA POLSKA 52/1 :29-34,2018

Effects of Tranexamic Acid Based on its Population Pharmacokinetics in Pediatric Patients Undergoing Distraction Osteogenesis for Craniosynostosis: Rotational Thromboelastometry (ROTEMTM) Analysis
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES 15/8 :788-795,2018

Direct versus indirect revascularization in the treatment of moyamoya disease.
JOURNAL OF NEUROSURGERY 129/2 :480-489,2018

Hemispherotomy and Functional Hemispherectomy: Indications and Outcomes
Journal of Epilepsy Research 8/1 :1-5,2018

Genomic analysis reveals secondary glioblastoma after radiotherapy in a subset of recurrent medulloblastomas
ACTA NEUROPATHOLOGICA 135/6 :939-953,2018

Neuropsychological impacts of indirect revascularization for pediatric moyamoya disease
CHILDS NERVOUS SYSTEM 34/6 :1199-1206,2018

Interregional metabolic connectivity of 2-deoxy-2[18 F]fluoro-D-glucose positron emission tomography in vagus nerve stimulation for pediatric patients with epilepsy: A retrospective cross-sectional study.
EPILEPSIA 59/12 :2,249-2,259,2018

Effect of Unshaven Hair with Absorbable Sutures and Early Postoperative Shampoo on Cranial Surgery Site Infection
PEDIATRIC NEUROSURGERY 53/1 :18-23,2018

Epilepsy Surgery for Children With Low-Grade Epilepsy-Associated Tumors: Factors Associated With Seizure Recurrence and Cognitive Function
PEDIATRIC NEUROLOGY 91/ :50-56,2019

Precise detection of low-level somatic mutation in resected epilepsy brain tissue.
ACTA NEUROPATHOLOGICA 138/6 :901-912,2019

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