강훈철
#신경#뇌전증#발달#학습장애#소아수면질환 진단 및 치료
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학력
연세대학교 의학과 학사(1992)
연세대학교 대학원 의학석사(2001)
연세대학교 대학원 의학박사(2006)
연세대학교 대학원 의학석사(2001)
연세대학교 대학원 의학박사(2006)
경력
1993년 연세대학교 세브란스병원 인턴 수료
2001년 연세대학교 세브란스병원 소아과 전공의 수료
2002년 연세대학교 세브란스병원 소아과 연구강사 수료
2002년-2008년 인제대학교 상계백병원 소아과, 뇌전증센터 조교수
2009년-2013년 연세대학교 세브란스병원 소아신경과 임상부교수
2013년-현재 연세대학교 세브란스병원 소아신경과 교수
2017.3.-현재 연세대학교 세브란스 어린이병원 소아신경과 과장
2001년 연세대학교 세브란스병원 소아과 전공의 수료
2002년 연세대학교 세브란스병원 소아과 연구강사 수료
2002년-2008년 인제대학교 상계백병원 소아과, 뇌전증센터 조교수
2009년-2013년 연세대학교 세브란스병원 소아신경과 임상부교수
2013년-현재 연세대학교 세브란스병원 소아신경과 교수
2017.3.-현재 연세대학교 세브란스 어린이병원 소아신경과 과장
논문
Factors Influencing the Evolution of West Syndrome to Lennox-Gastaut Syndrome
Pediatric Neurology 41/2 :111-113,2009
Clinical characteristics of patients with non-specific and non-categorized mitochondrial diseases
Acta Paediatrica 98/11 :1825-1829,2009
Outcome of surgical treatment in non-lesional intractable childhood epilepsy
Seizure-European Journal Of Epilepsy 18/9 :625-629,2009
편두통의 전 단계인 소아기주기성증후군의 다기관 임상 연구 : 국제두통질환분류 제2판 제1차 수정판 적용
Korean Journal of Pediatrics 52/5 :557-566,2009
저산소 허혈 뇌 손상을 유발시킨 미성숙 흰쥐에서 마우스 골수 기원 중간엽 줄기 세포 이식 후 기능 회복
Korean Journal of Pediatrics 52/7 :824-831,2009
Ictal single-photon emission computed tomography with slow dye injection for determining primary epileptic foci in infantile spasms
Korean Journal of Pediatrics 52/7 :804-810,2009
Resective Pediatric Epilepsy Surgery in Lennox-Gastaut Syndrome
Pediatrics 125/1 :E58-E66,2010
Comparison of temporal lobectomies of children and adults with intractable temporal lobe epilepsy
CHILDS NERVOUS SYSTEM 26/ :177-183,2010
Efficacy and Safety of Adjunctive Levetiracetam Therapy in Pediatric Intractable Epilepsy
Pediatric Neurology 42/2 :86-92,2010
Efficacy and tolerability of adjunctive therapy with zonisamide in childhood intractable epilepsy
Brain & Development 32/2 :208-212,2010
Behavioral improvement after transplantation of neural precursors derived from embryonic stem cells into the globally ischemic brain of adolescent rats
Brain & Development 32/8 :658-668,2010
외측두엽 간질의 수술적 결과
대한소아신경외과학회지 7/1 :31-40,2010
Iron deficiency in children with mitochondrial disease
Metabolic Brain Disease 25/2 :185-189,2010
Electrocardiography as an early cardiac screening test in children with mitochondrial disease
Korean Journal of Pediatrics 54/5 :644-647,2010
Surgical Outcomes and Prognostic Factors after Epilepsy Surgery in Children with Extratemporal Lobe Epilepsy
Journal of the Korean Child Neurology Society(대한소아신경학회지) 18/1 :20-32,2010
소아청소년기 수면 장애의 임상적 연구
Journal of the Korean Child Neurology Society(대한소아신경학회지) 18/2 :187-196,2010
중심-측두엽 극파 동반 양성 간질에서의 인지 행동 관찰 및 topiramate 1일 1회 투약 효과
Journal of the Korean Child Neurology Society(대한소아신경학회지) 18/2 :206-213,2010
Usefulness of liquid ketogenic milk for intractable childhood epilepsy
e-SPEN, the European e-journal of Clinical Nutrition and Metabolism 5/5 :203-207,2010
Risk factors of ocular involvement in children with mitochondrial respiratory chain complex defect
Korean Journal of Pediatrics 53/12 :994-999,2010
Leigh 증후군 환아에서의 안과적 이상 소견
Korean Journal of Pediatrics 53/2 :163-166,2010
Comparison of short-versus long-term ketogenic diet for intractable infantile spasms
EPILEPSIA 52/4 :781-787,2011
Neuroimaging in identifying focal cortical dysplasia and prognostic factors in pediatric and adolescent epilepsy surgery
EPILEPSIA 52/4 :722-727,2011
Uncovered primary seizure foci in Lennox-Gastaut syndrome after corpus callosotomy
BRAIN & DEVELOPMENT 33/8 :672-677,2011
Comparative trial of low- and high-dose zonisamide as monotherapy for childhood epilepsy
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY 20/7 :558-563,2011
Induced Pluripotent Stem Cell Models from X-linked Adrenoleukodystrophy Patients
ANNALS OF NEUROLOGY 70/3 :402-409,2011
Evaluation of Algorithms for Intracranial EEG (iEEG) Source Imaging of Extended Sources: Feasibility of Using iEEG Source Imaging for Localizing Epileptogenic Zones in Secondary Generalized Epilepsy
BRAIN TOPOGRAPHY 24/ :91-104,2011
Localization of ictal onset zones in Lennox-Gastaut syndrome using directional connectivity analysis of intracranial electroencephalography
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY 20/6 :449-457,2011
A Case of Metachromatic Leukodystrophy Confirmed by Molecular Genetic Analysis
Journal of the Korean Child Neurology Society(대한소아신경학회지) 18/3 :272-276,2011
A Case of Early Onset MELAS Patient with Wolff-Parkinson-White Syndrome
Journal of the Korean Child Neurology Society(대한소아신경학회지) 18/3 :266-271,2011
A1 Segment Hypoplasia/aplasia Detected by Magnetic Resonance Angiography in Neuropediatric Patients
Journal of the Korean Child Neurology Society(대한소아신경학회지) 18/3 :231-239,2011
Various indications for a modified Atkins diet in intractable childhood epilepsy
BRAIN & DEVELOPMENT 34/ :570-575,2012
Highly pure and expandable PSA-NCAM-positive neural precursors from human ESC and iPSC-derived neural rosettes
PLOS ONE 7/7 :e39715-e39715,2012
Rufinamide as an adjuvant treatment in children with Lennox-Gastaut syndrome
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY 21/4 :288-291,2012
Genetic and Epileptic Features in Rett Syndrome
YONSEI MEDICAL JOURNAL 53/3 :495-500,2012
Localization of ictal onset zones in Lennox-Gastaut syndrome (LGS) based on information theoretical time delay analysis of intracranial electroencephalography (iEEG)
EPILEPSY RESEARCH 99/1-2 :78-86,2012
발작과 뇌전증에 대한 개정된 용어 및 개념: ILAE의 분류 및 용어 관련 보고(2005-2009) 한글판
Journal of Korean Epilepsy Society 16/1 :1-8,2012
Safety and role of ketogenic parenteral nutrition for intractable childhood epilepsy
BRAIN & DEVELOPMENT 34/8 :620-624,2012
Disease-specific induced pluripotent stem cells: a platform for human disease modeling and drug discovery.
EXPERIMENTAL AND MOLECULAR MEDICINE 44/3 :202-213,2012
Early cardiac evaluation in children with non-specific mitochondrial disease with isolated mitochondrial respiratory chain complex i defect
JOURNAL OF PAEDIATRICS AND CHILD HEALTH 48/11 :1016-1020,2012
Is the ketogenic diet effective in specific epilepsy syndromes?
EPILEPSY RESEARCH 100/3 :252-257,2012
A multicenter trial of oxcarbazepine oral suspension monotherapy in children newly diagnosed with partial seizures: A clinical and cognitive evaluation
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY 21/9 :679-684,2012
New Classification of Focal Cortical Dysplasia: Application to Practical Diagnosis
Journal of Epilepsy Research 2/2 :38-42,2012
Epilepsy in Korean patients with Angelman syndrome
Korean Journal of Pediatrics 55/5 :171-176,2012
Catch-up growth after long-term implementation and weaning from ketogenic diet in pediatric epileptic patients
CLINICAL NUTRITION 32/1 :98-103,2013
Mitochondrial disease and epilepsy
BRAIN & DEVELOPMENT 35/35 :757-761,2013
The Genetically Modified Polysialylated Form of Neural Cell Adhesion Molecule-Positive Cells for Potential Treatment of X-Linked Adrenoleukodystrophy
YONSEI MEDICAL JOURNAL 54/1 :246-252,2013
Seizure outcome of infantile spasms with focal cortical dysplasia
BRAIN & DEVELOPMENT 35/35 :816-820,2013
Clinical analysis of catastrophic epilepsy in infancy and early childhood: Results of the Far-East Asia Catastrophic Epilepsy (FACE) study group
BRAIN & DEVELOPMENT 35/1 :786-792,2013
Localization of epileptogenic zones in Lennox-Gastaut syndrome using frequency domain source imaging of intracranial electroencephalography: a preliminary investigation
PHYSIOLOGICAL MEASUREMENT 34/1 :247-263,2013
Lower fat and better quality diet therapy for children with pharmacoresistant epilepsy
Korean Journal of Pediatrics 56/8 :327-331,2013
Interferon beta-1b Treatment in a Korean Girl with Multiple Sclerosis
Journal of the Korean Child Neurology Society(대한소아신경학회지) 21/1 :28-32,2013
Clinical Presentations and the Bacterial Meningitis Score in Children with Cerebrospinal Fluid (CSF) Pleocytosis
Journal of the Korean Child Neurology Society(대한소아신경학회지) 21/2 :46-52,2013
Schilder's disease in a young child with tumefactive demyelinating brain lesion
NEUROLOGY ASIA 18/4 :419-421,2013
The Significance of Insular Hypometabolism in Temporal Lobe Epilepsy in Children
Journal of Epilepsy Research 3/2 :54-62,2013
Epilepsy surgery in pediatric intractable epilepsy with destructive encephalopathy.
Journal of Epilepsy Research 3/2 :48-53,2013
Polyunsaturated fatty acid-enriched diet therapy for a child with epilepsy
BRAIN & DEVELOPMENT 36/Issue2 :163-166,2014
Changing name of epilepsy in Korea; cerebroelectric disorder(noi-jeon-jeung,뇌전증,): my epilepsy story.
EPILEPSIA 55/3 :384-386,2014
Clinical and Genetic Aspects in Twelve Korean Patients with Adrenomyeloneuropathy
YONSEI MEDICAL JOURNAL 55/3 :676-682,2014
Outcomes of epilepsy surgery in childhood-onset epileptic encephalopathy
BRAIN & DEVELOPMENT 36/6 :496-504,2014
Primary central nervous system anaplastic large cell lymphoma presenting initially with meningitis
NEUROLOGY ASIA 19/ :231-234,2014
Combined Use of Multiple Computational Intracranial EEG Analysis Techniques for the Localization of Epileptogenic Zones in Lennox-Gastaut Syndrome
CLINICAL EEG AND NEUROSCIENCE 45/3 :169-178,2014
The impact of an exercise therapy on psychosocial health of children with benign epilepsy: A pilot study
EPILEPSY & BEHAVIOR 37/ :151-156,2014
Epilepsy-related clinical factors and psychosocial functions in pediatric epilepsy
EPILEPSY & BEHAVIOR 37c/- :43-48,2014
Adjunctive levetiracetam treatment in pediatric lennox-gastaut syndrome
PEDIATRIC NEUROLOGY 51/4 :527-531,2014
A modified Atkin's diet for an infant with pyruvate dehydrogenase complex deficiency confirmed by PDHA1 gene mutation
NEUROLOGY ASIA 19/3 :327-329,2014
Congenital muscular dystrophy type 1A with residual merosin expression
Korean Journal of Pediatrics 57/3 :149-152,2014
Induced pluripotent stem cells for modeling of pediatric neurological disorders
BIOTECHNOLOGY JOURNAL 9/7 :871-881,2014
Psychological Problems and Clinical Outcomes of Children with Psychogenic Non-Epileptic Seizures
YONSEI MEDICAL JOURNAL 55/6 :1556-1561,2014
Isolated Cerebellar Variant of Adrenoleukodystrophy with a de novo Adenosine Triphosphate-Binding Cassette D1 (ABCD1) Gene Mutation
YONSEI MEDICAL JOURNAL 55/4 :1157-1160,2014
Wernicke’s encephalopathy in a child with high dose thiamine therapy.
Korean Journal of Pediatrics 57/11 :496-499,2014
Localization of epileptogenic zones in Lennox-Gastaut syndrome (LGS) using graph theoretical analysis of ictal intracranial EEG: A preliminary investigation
BRAIN & DEVELOPMENT 37/1 :29-36,2015
Neurocognitive function in children after anterior temporal lobectomy with amygdalohippocampectomy
PEDIATRIC NEUROLOGY 52/1 :88-93,2015
Long-term prognosis of patients with Lennox-Gastaut syndrome in recent decades
EPILEPSY RESEARCH 110/- :10-19,2015
Screening for depression and anxiety disorder in children with headache
Korean Journal of Pediatrics 58/2 :64-68,2015
Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy
NATURE MEDICINE 21/4 :395-400,2015
Neuropsychological effects of levetiracetam and carbamazepine in children with focal epilepsy
NEUROLOGY 84/23 :2312-2319,2015
결절성 경화증 (Tuberous sclerosis) 환자에서 뇌실막밑 거대세포 별아교세포종의 (Subependymal giant cell astrocytoma) 치료
Journal of the Korean Child Neurology Society(대한소아신경학회지) 23/1 :1-6,2015
Applying the bacterial meningitis score in children with cerebrospinal fluid pleocytosis: a single center’s experience
Korean Journal of Pediatrics 58/7 :251-255,2015
Chronic inflammatory demyelinating polyneuropathy in children: a report of four patients with variable relapsing courses
Korean Journal of Pediatrics 58/5 :194-198,2015
부신백질형성장애증 섬유모세포에서 발프로산의 항산화능
Journal of the Korean Child Neurology Society(대한소아신경학회지) 23/2 :45-50,2015
Clinical and Genetic Aspects of the Segmental Overgrowth Spectrum Due to Somatic Mutations in PIK3CA
JOURNAL OF PEDIATRICS 167/5 :957-962,2015
An AKT3-FOXG1-reelin network underlies defective migration in human focal malformations of cortical development
NATURE MEDICINE 21/12 :1445-1456,2015
Spinal Cord Tumor Presenting as Secondary Torticollis: A Case Report
Journal of the Korean Child Neurology Society(대한소아신경학회지) 23/3 :135-137,2015
Parry-Romberg syndrome with ipsilateral hemipons involvement presenting as monoplegic ataxia
Korean Journal of Pediatrics 58/9 :354-357,2015
Efficacy of the classic ketogenic and the modified Atkins diets in refractory childhood epilepsy
EPILEPSIA 57/1 :51-58,2016
The Impact of a 35-Week Long-Term Exercise Therapy on Psychosocial Health of Children With Benign Epilepsy
JOURNAL OF CHILD NEUROLOGY 31/8 :985-990,2016
Surgical treatment of pediatric focal cortical dysplasia: Clinical spectrum and surgical outcome
NEUROLOGY 30;87/9 :945-951,2016
미토콘드리아 호흡연쇄 복합체 결함이 동반된 난치성 소아 뇌전증에서의 Zonisamide 부가 요법
Journal of the Korean Child Neurology Society(대한소아신경학회지) 24/3 :89-94,2016
25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome
NATURE COMMUNICATIONS 7/ :13,129-,2016
X연관 부신백질이영양증의 분류, 진단 및 치료의 최신 지견
Journal of the Korean Child Neurology Society(대한소아신경학회지) 24/3 :71-84,2016
Juvenile Myasthenia Gravis in Korea: Subgroup Analysis According to Sex and Onset Age
JOURNAL OF CHILD NEUROLOGY 31/14 :1561-4568,2016
Epilepsy Characteristics and Clinical Outcome in Patients With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes (MELAS)
PEDIATRIC NEUROLOGY 64/- :59-65,2016
Ketogenic Diet for Children with Epilepsy : A Practical Meal Plan in a Hospital
Clinical nutrition research 5/1 :60-63,2016
Automatic Identification of Interictal Epileptiform Discharges in Secondary Generalized Epilepsy.
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE 2016/Arti :1-10,2016
Estimating the Prevalence of Treated Epilepsy Using Administrative Health Data and Its Validity: ESSENCE Study
JOURNAL OF CLINICAL NEUROLOGY 12/4 :434-440,2016
Cause of Death in Children With Mitochondrial Diseases
PEDIATRIC NEUROLOGY 66/ :82-88,2017
Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia
AMERICAN JOURNAL OF HUMAN GENETICS 100/3 :454-472,2017
Ketogenic Diet for the Management of Epilepsy Associated with Tuberous Sclerosis Complex in Children
Journal of Epilepsy Research 7/1 :45-49,2017
Could Cannabidiol be a Treatment Option for Intractable Childhood and Adolescent Epilepsy?
Journal of Epilepsy Research 7/1 :16-20,2017
Long-term epilepsy-associated tumor in the amygdala of a 16-year-old boy: report of a rare case having intranuclear filaments
BRAIN TUMOR PATHOLOGY 34/4 :172-178,2017
드라베 증후군의 SCN1A 유전자 변이 양상
Journal of the Korean Child Neurology Society(대한소아신경학회지) 25/1 :9-12,2017
A Patient Diagnosed with Spinocerebellar Ataxia Type 5 associated with SPTBN2: Case Repor
Journal of the Korean Child Neurology Society(대한소아신경학회지) 25/3 :200-203,2017
Quinidine Trial in a Patient with Epilepsy of Infancy with Migrating Focal Seizure and KCNT1 Mutation
Journal of the Korean Child Neurology Society(대한소아신경학회지) 25/3 :169-173,2017
Discontinuing Antiepileptic Drugs after Pediatric Epilepsy Surgery for Focal Cortical Dysplasia
Journal of the Korean Child Neurology Society(대한소아신경학회지) 25/3 :127-132,2017
Low glycemic index treatment in patients with drug-resistant epilepsy
BRAIN & DEVELOPMENT 39/8 :687-692,2017
Mowat-Wilson syndrome presenting with fever-associated seizures.
EPILEPTIC DISORDERS 19/4 :481-485,2017
Generation of two induced pluripotent stem cell (iPSC) lines from X-linked adrenoleukodystrophy (X-ALD) patients with adrenomyeloneuropathy (AMN)
STEM CELL RESEARCH 25/ :46-49,2017
Alpers-Huttenlocher Syndrome First Presented with Hepatic Failure: Can Liver Transplantation Be Considered as Treatment Option?
Pediatric Gastroenterology, Hepatology & Nutrition 20/4 :259-262,2017
Efficacy of Stiripentol in Dravet Syndrome with or without SCN1A Mutations
JOURNAL OF CLINICAL NEUROLOGY 14/1 :22-28,2018
Efficient strategy for the molecular diagnosis of intractable early-onset epilepsy using targeted gene sequencing
BMC MEDICAL GENOMICS 11/1 :6-,2018
Targeted gene panel and genotype-phenotype correlation in children with developmental and epileptic encephalopathy
EPILEPSY RESEARCH 141/ :48-55,2018
Differential effects on sodium current impairments by distinct SCN1A mutations in GABAergic neurons derived from Dravet syndrome patients
BRAIN & DEVELOPMENT 40/4 :287-298,2018
Vigabatrin and high-dose prednisolone therapy for patients with West syndrome
EPILEPSY RESEARCH 145/1 :127-133,2018
Adverse Events During Perampanel Adjunctive Therapy in Intractable Epilepsy
JOURNAL OF CLINICAL NEUROLOGY 14/3 :296-302,2018
Optimal clinical management of children receiving dietary therapies for epilepsy: Updated recommendations of the International Ketogenic Diet Study Group
EPILEPSIA 3/2 :175-192,2018
The efficacy of ketogenic diet for specific genetic mutation in developmental and epileptic encephalopathy
FRONTIERS IN NEUROLOGY 9/JUL :530-538,2018
Three-dimensional brain-like microenvironments facilitate the direct reprogramming of fibroblasts into therapeutic neurons
Nature biomedical engineering 2/7 :522-539,2018
Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination
NEURON 99/1 :83-97,2018
Interregional metabolic connectivity of 2-deoxy-2[18 F]fluoro-D-glucose positron emission tomography in vagus nerve stimulation for pediatric patients with epilepsy: A retrospective cross-sectional study.
EPILEPSIA 59/12 :2,249-2,259,2018
Early Diagnosis of KBG Syndrome Using Diagnostic Exome Sequencing
Journal of the Korean Child Neurology Society(대한소아신경학회지) 26/4 :272-275,2018
Brain somatic mutations in SLC35A2 cause intractable epilepsy with aberrant N-glycosylation
Neurology: Genetics 4/6 :e294-e302,2018
Long-term Outcome of Resective Epilepsy Surgery in Patients With Lennox-Gastaut Syndrome
PEDIATRICS 142/4 :e20180449-e20180459,2018
Age-Based Characteristics of West Syndrome in Patients with Mitochondrial Disease
Journal of the Korean Child Neurology Society(대한소아신경학회지) 26/4 :197-204,2018
Rufinamide efficacy and safety in children aged 1-4?years with Lennox-Gastaut syndrome
BRAIN & DEVELOPMENT 40/10 :897-903,2018
BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors
NATURE MEDICINE 24/11 :1,662-1,668,2018
Epilepsy Surgery for Children With Low-Grade Epilepsy-Associated Tumors: Factors Associated With Seizure Recurrence and Cognitive Function
PEDIATRIC NEUROLOGY 91/ :50-56,2019
Medication self-management and the quality of discharge education among parents of children with epilepsy
EPILEPSY & BEHAVIOR 94/5 :14-19,2019
Aligned Brain Extracellular Matrix Promotes Differentiation and Myelination of Human-Induced Pluripotent Stem Cell-Derived Oligodendrocytes
ACS APPLIED MATERIALS & INTERFACES 11/17 :15,344-15,353,2019
The use of technical replication for detection of low-level somatic mutations in next-generation sequencing
NATURE COMMUNICATIONS 10/1 :1047-,2019
A Child With Lymphangioma Due to Somatic Mutation in PIK3CA Successfully Treated With Everolimus
PEDIATRIC NEUROLOGY 91/ :65-67,2019
Clobazam as an adjunctive treatment for infantile spasms
EPILEPSY & BEHAVIOR 95/ :161-165,2019
Short- and long-term seizure-free outcomes of dietary treatment in infants according to etiology
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY 71/ :100-104,2019
Optimized Treatment for Infantile Spasms: Vigabatrin versus Prednisolone versus Combination Therapy
Journal of Clinical Medicine 8/10 :1591-1-1591-10,2019
Proband-Only Clinical Exome Sequencing for Neurodevelopmental Disabilities
PEDIATRIC NEUROLOGY 99/ :47-54,2019
Clinical Implementation of Targeted Gene Sequencing for Malformation of Cortical Development
PEDIATRIC NEUROLOGY 99/ :47-54,2019
Genetic and clinical features of SCN8A developmental and epileptic encephalopathy
EPILEPSY RESEARCH 158/1 :e106222-,2019
Precise detection of low-level somatic mutation in resected epilepsy brain tissue.
ACTA NEUROPATHOLOGICA 138/6 :901-912,2019
Brain somatic mutations in MTOR reveal translational dysregulations underlying intractable focal epilepsy
JOURNAL OF CLINICAL INVESTIGATION 129/10 :4,207-4,223,2019
Pediatric Neurology 41/2 :111-113,2009
Clinical characteristics of patients with non-specific and non-categorized mitochondrial diseases
Acta Paediatrica 98/11 :1825-1829,2009
Outcome of surgical treatment in non-lesional intractable childhood epilepsy
Seizure-European Journal Of Epilepsy 18/9 :625-629,2009
편두통의 전 단계인 소아기주기성증후군의 다기관 임상 연구 : 국제두통질환분류 제2판 제1차 수정판 적용
Korean Journal of Pediatrics 52/5 :557-566,2009
저산소 허혈 뇌 손상을 유발시킨 미성숙 흰쥐에서 마우스 골수 기원 중간엽 줄기 세포 이식 후 기능 회복
Korean Journal of Pediatrics 52/7 :824-831,2009
Ictal single-photon emission computed tomography with slow dye injection for determining primary epileptic foci in infantile spasms
Korean Journal of Pediatrics 52/7 :804-810,2009
Resective Pediatric Epilepsy Surgery in Lennox-Gastaut Syndrome
Pediatrics 125/1 :E58-E66,2010
Comparison of temporal lobectomies of children and adults with intractable temporal lobe epilepsy
CHILDS NERVOUS SYSTEM 26/ :177-183,2010
Efficacy and Safety of Adjunctive Levetiracetam Therapy in Pediatric Intractable Epilepsy
Pediatric Neurology 42/2 :86-92,2010
Efficacy and tolerability of adjunctive therapy with zonisamide in childhood intractable epilepsy
Brain & Development 32/2 :208-212,2010
Behavioral improvement after transplantation of neural precursors derived from embryonic stem cells into the globally ischemic brain of adolescent rats
Brain & Development 32/8 :658-668,2010
외측두엽 간질의 수술적 결과
대한소아신경외과학회지 7/1 :31-40,2010
Iron deficiency in children with mitochondrial disease
Metabolic Brain Disease 25/2 :185-189,2010
Electrocardiography as an early cardiac screening test in children with mitochondrial disease
Korean Journal of Pediatrics 54/5 :644-647,2010
Surgical Outcomes and Prognostic Factors after Epilepsy Surgery in Children with Extratemporal Lobe Epilepsy
Journal of the Korean Child Neurology Society(대한소아신경학회지) 18/1 :20-32,2010
소아청소년기 수면 장애의 임상적 연구
Journal of the Korean Child Neurology Society(대한소아신경학회지) 18/2 :187-196,2010
중심-측두엽 극파 동반 양성 간질에서의 인지 행동 관찰 및 topiramate 1일 1회 투약 효과
Journal of the Korean Child Neurology Society(대한소아신경학회지) 18/2 :206-213,2010
Usefulness of liquid ketogenic milk for intractable childhood epilepsy
e-SPEN, the European e-journal of Clinical Nutrition and Metabolism 5/5 :203-207,2010
Risk factors of ocular involvement in children with mitochondrial respiratory chain complex defect
Korean Journal of Pediatrics 53/12 :994-999,2010
Leigh 증후군 환아에서의 안과적 이상 소견
Korean Journal of Pediatrics 53/2 :163-166,2010
Comparison of short-versus long-term ketogenic diet for intractable infantile spasms
EPILEPSIA 52/4 :781-787,2011
Neuroimaging in identifying focal cortical dysplasia and prognostic factors in pediatric and adolescent epilepsy surgery
EPILEPSIA 52/4 :722-727,2011
Uncovered primary seizure foci in Lennox-Gastaut syndrome after corpus callosotomy
BRAIN & DEVELOPMENT 33/8 :672-677,2011
Comparative trial of low- and high-dose zonisamide as monotherapy for childhood epilepsy
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY 20/7 :558-563,2011
Induced Pluripotent Stem Cell Models from X-linked Adrenoleukodystrophy Patients
ANNALS OF NEUROLOGY 70/3 :402-409,2011
Evaluation of Algorithms for Intracranial EEG (iEEG) Source Imaging of Extended Sources: Feasibility of Using iEEG Source Imaging for Localizing Epileptogenic Zones in Secondary Generalized Epilepsy
BRAIN TOPOGRAPHY 24/ :91-104,2011
Localization of ictal onset zones in Lennox-Gastaut syndrome using directional connectivity analysis of intracranial electroencephalography
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY 20/6 :449-457,2011
A Case of Metachromatic Leukodystrophy Confirmed by Molecular Genetic Analysis
Journal of the Korean Child Neurology Society(대한소아신경학회지) 18/3 :272-276,2011
A Case of Early Onset MELAS Patient with Wolff-Parkinson-White Syndrome
Journal of the Korean Child Neurology Society(대한소아신경학회지) 18/3 :266-271,2011
A1 Segment Hypoplasia/aplasia Detected by Magnetic Resonance Angiography in Neuropediatric Patients
Journal of the Korean Child Neurology Society(대한소아신경학회지) 18/3 :231-239,2011
Various indications for a modified Atkins diet in intractable childhood epilepsy
BRAIN & DEVELOPMENT 34/ :570-575,2012
Highly pure and expandable PSA-NCAM-positive neural precursors from human ESC and iPSC-derived neural rosettes
PLOS ONE 7/7 :e39715-e39715,2012
Rufinamide as an adjuvant treatment in children with Lennox-Gastaut syndrome
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY 21/4 :288-291,2012
Genetic and Epileptic Features in Rett Syndrome
YONSEI MEDICAL JOURNAL 53/3 :495-500,2012
Localization of ictal onset zones in Lennox-Gastaut syndrome (LGS) based on information theoretical time delay analysis of intracranial electroencephalography (iEEG)
EPILEPSY RESEARCH 99/1-2 :78-86,2012
발작과 뇌전증에 대한 개정된 용어 및 개념: ILAE의 분류 및 용어 관련 보고(2005-2009) 한글판
Journal of Korean Epilepsy Society 16/1 :1-8,2012
Safety and role of ketogenic parenteral nutrition for intractable childhood epilepsy
BRAIN & DEVELOPMENT 34/8 :620-624,2012
Disease-specific induced pluripotent stem cells: a platform for human disease modeling and drug discovery.
EXPERIMENTAL AND MOLECULAR MEDICINE 44/3 :202-213,2012
Early cardiac evaluation in children with non-specific mitochondrial disease with isolated mitochondrial respiratory chain complex i defect
JOURNAL OF PAEDIATRICS AND CHILD HEALTH 48/11 :1016-1020,2012
Is the ketogenic diet effective in specific epilepsy syndromes?
EPILEPSY RESEARCH 100/3 :252-257,2012
A multicenter trial of oxcarbazepine oral suspension monotherapy in children newly diagnosed with partial seizures: A clinical and cognitive evaluation
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY 21/9 :679-684,2012
New Classification of Focal Cortical Dysplasia: Application to Practical Diagnosis
Journal of Epilepsy Research 2/2 :38-42,2012
Epilepsy in Korean patients with Angelman syndrome
Korean Journal of Pediatrics 55/5 :171-176,2012
Catch-up growth after long-term implementation and weaning from ketogenic diet in pediatric epileptic patients
CLINICAL NUTRITION 32/1 :98-103,2013
Mitochondrial disease and epilepsy
BRAIN & DEVELOPMENT 35/35 :757-761,2013
The Genetically Modified Polysialylated Form of Neural Cell Adhesion Molecule-Positive Cells for Potential Treatment of X-Linked Adrenoleukodystrophy
YONSEI MEDICAL JOURNAL 54/1 :246-252,2013
Seizure outcome of infantile spasms with focal cortical dysplasia
BRAIN & DEVELOPMENT 35/35 :816-820,2013
Clinical analysis of catastrophic epilepsy in infancy and early childhood: Results of the Far-East Asia Catastrophic Epilepsy (FACE) study group
BRAIN & DEVELOPMENT 35/1 :786-792,2013
Localization of epileptogenic zones in Lennox-Gastaut syndrome using frequency domain source imaging of intracranial electroencephalography: a preliminary investigation
PHYSIOLOGICAL MEASUREMENT 34/1 :247-263,2013
Lower fat and better quality diet therapy for children with pharmacoresistant epilepsy
Korean Journal of Pediatrics 56/8 :327-331,2013
Interferon beta-1b Treatment in a Korean Girl with Multiple Sclerosis
Journal of the Korean Child Neurology Society(대한소아신경학회지) 21/1 :28-32,2013
Clinical Presentations and the Bacterial Meningitis Score in Children with Cerebrospinal Fluid (CSF) Pleocytosis
Journal of the Korean Child Neurology Society(대한소아신경학회지) 21/2 :46-52,2013
Schilder's disease in a young child with tumefactive demyelinating brain lesion
NEUROLOGY ASIA 18/4 :419-421,2013
The Significance of Insular Hypometabolism in Temporal Lobe Epilepsy in Children
Journal of Epilepsy Research 3/2 :54-62,2013
Epilepsy surgery in pediatric intractable epilepsy with destructive encephalopathy.
Journal of Epilepsy Research 3/2 :48-53,2013
Polyunsaturated fatty acid-enriched diet therapy for a child with epilepsy
BRAIN & DEVELOPMENT 36/Issue2 :163-166,2014
Changing name of epilepsy in Korea; cerebroelectric disorder(noi-jeon-jeung,뇌전증,): my epilepsy story.
EPILEPSIA 55/3 :384-386,2014
Clinical and Genetic Aspects in Twelve Korean Patients with Adrenomyeloneuropathy
YONSEI MEDICAL JOURNAL 55/3 :676-682,2014
Outcomes of epilepsy surgery in childhood-onset epileptic encephalopathy
BRAIN & DEVELOPMENT 36/6 :496-504,2014
Primary central nervous system anaplastic large cell lymphoma presenting initially with meningitis
NEUROLOGY ASIA 19/ :231-234,2014
Combined Use of Multiple Computational Intracranial EEG Analysis Techniques for the Localization of Epileptogenic Zones in Lennox-Gastaut Syndrome
CLINICAL EEG AND NEUROSCIENCE 45/3 :169-178,2014
The impact of an exercise therapy on psychosocial health of children with benign epilepsy: A pilot study
EPILEPSY & BEHAVIOR 37/ :151-156,2014
Epilepsy-related clinical factors and psychosocial functions in pediatric epilepsy
EPILEPSY & BEHAVIOR 37c/- :43-48,2014
Adjunctive levetiracetam treatment in pediatric lennox-gastaut syndrome
PEDIATRIC NEUROLOGY 51/4 :527-531,2014
A modified Atkin's diet for an infant with pyruvate dehydrogenase complex deficiency confirmed by PDHA1 gene mutation
NEUROLOGY ASIA 19/3 :327-329,2014
Congenital muscular dystrophy type 1A with residual merosin expression
Korean Journal of Pediatrics 57/3 :149-152,2014
Induced pluripotent stem cells for modeling of pediatric neurological disorders
BIOTECHNOLOGY JOURNAL 9/7 :871-881,2014
Psychological Problems and Clinical Outcomes of Children with Psychogenic Non-Epileptic Seizures
YONSEI MEDICAL JOURNAL 55/6 :1556-1561,2014
Isolated Cerebellar Variant of Adrenoleukodystrophy with a de novo Adenosine Triphosphate-Binding Cassette D1 (ABCD1) Gene Mutation
YONSEI MEDICAL JOURNAL 55/4 :1157-1160,2014
Wernicke’s encephalopathy in a child with high dose thiamine therapy.
Korean Journal of Pediatrics 57/11 :496-499,2014
Localization of epileptogenic zones in Lennox-Gastaut syndrome (LGS) using graph theoretical analysis of ictal intracranial EEG: A preliminary investigation
BRAIN & DEVELOPMENT 37/1 :29-36,2015
Neurocognitive function in children after anterior temporal lobectomy with amygdalohippocampectomy
PEDIATRIC NEUROLOGY 52/1 :88-93,2015
Long-term prognosis of patients with Lennox-Gastaut syndrome in recent decades
EPILEPSY RESEARCH 110/- :10-19,2015
Screening for depression and anxiety disorder in children with headache
Korean Journal of Pediatrics 58/2 :64-68,2015
Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy
NATURE MEDICINE 21/4 :395-400,2015
Neuropsychological effects of levetiracetam and carbamazepine in children with focal epilepsy
NEUROLOGY 84/23 :2312-2319,2015
결절성 경화증 (Tuberous sclerosis) 환자에서 뇌실막밑 거대세포 별아교세포종의 (Subependymal giant cell astrocytoma) 치료
Journal of the Korean Child Neurology Society(대한소아신경학회지) 23/1 :1-6,2015
Applying the bacterial meningitis score in children with cerebrospinal fluid pleocytosis: a single center’s experience
Korean Journal of Pediatrics 58/7 :251-255,2015
Chronic inflammatory demyelinating polyneuropathy in children: a report of four patients with variable relapsing courses
Korean Journal of Pediatrics 58/5 :194-198,2015
부신백질형성장애증 섬유모세포에서 발프로산의 항산화능
Journal of the Korean Child Neurology Society(대한소아신경학회지) 23/2 :45-50,2015
Clinical and Genetic Aspects of the Segmental Overgrowth Spectrum Due to Somatic Mutations in PIK3CA
JOURNAL OF PEDIATRICS 167/5 :957-962,2015
An AKT3-FOXG1-reelin network underlies defective migration in human focal malformations of cortical development
NATURE MEDICINE 21/12 :1445-1456,2015
Spinal Cord Tumor Presenting as Secondary Torticollis: A Case Report
Journal of the Korean Child Neurology Society(대한소아신경학회지) 23/3 :135-137,2015
Parry-Romberg syndrome with ipsilateral hemipons involvement presenting as monoplegic ataxia
Korean Journal of Pediatrics 58/9 :354-357,2015
Efficacy of the classic ketogenic and the modified Atkins diets in refractory childhood epilepsy
EPILEPSIA 57/1 :51-58,2016
The Impact of a 35-Week Long-Term Exercise Therapy on Psychosocial Health of Children With Benign Epilepsy
JOURNAL OF CHILD NEUROLOGY 31/8 :985-990,2016
Surgical treatment of pediatric focal cortical dysplasia: Clinical spectrum and surgical outcome
NEUROLOGY 30;87/9 :945-951,2016
미토콘드리아 호흡연쇄 복합체 결함이 동반된 난치성 소아 뇌전증에서의 Zonisamide 부가 요법
Journal of the Korean Child Neurology Society(대한소아신경학회지) 24/3 :89-94,2016
25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome
NATURE COMMUNICATIONS 7/ :13,129-,2016
X연관 부신백질이영양증의 분류, 진단 및 치료의 최신 지견
Journal of the Korean Child Neurology Society(대한소아신경학회지) 24/3 :71-84,2016
Juvenile Myasthenia Gravis in Korea: Subgroup Analysis According to Sex and Onset Age
JOURNAL OF CHILD NEUROLOGY 31/14 :1561-4568,2016
Epilepsy Characteristics and Clinical Outcome in Patients With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes (MELAS)
PEDIATRIC NEUROLOGY 64/- :59-65,2016
Ketogenic Diet for Children with Epilepsy : A Practical Meal Plan in a Hospital
Clinical nutrition research 5/1 :60-63,2016
Automatic Identification of Interictal Epileptiform Discharges in Secondary Generalized Epilepsy.
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE 2016/Arti :1-10,2016
Estimating the Prevalence of Treated Epilepsy Using Administrative Health Data and Its Validity: ESSENCE Study
JOURNAL OF CLINICAL NEUROLOGY 12/4 :434-440,2016
Cause of Death in Children With Mitochondrial Diseases
PEDIATRIC NEUROLOGY 66/ :82-88,2017
Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia
AMERICAN JOURNAL OF HUMAN GENETICS 100/3 :454-472,2017
Ketogenic Diet for the Management of Epilepsy Associated with Tuberous Sclerosis Complex in Children
Journal of Epilepsy Research 7/1 :45-49,2017
Could Cannabidiol be a Treatment Option for Intractable Childhood and Adolescent Epilepsy?
Journal of Epilepsy Research 7/1 :16-20,2017
Long-term epilepsy-associated tumor in the amygdala of a 16-year-old boy: report of a rare case having intranuclear filaments
BRAIN TUMOR PATHOLOGY 34/4 :172-178,2017
드라베 증후군의 SCN1A 유전자 변이 양상
Journal of the Korean Child Neurology Society(대한소아신경학회지) 25/1 :9-12,2017
A Patient Diagnosed with Spinocerebellar Ataxia Type 5 associated with SPTBN2: Case Repor
Journal of the Korean Child Neurology Society(대한소아신경학회지) 25/3 :200-203,2017
Quinidine Trial in a Patient with Epilepsy of Infancy with Migrating Focal Seizure and KCNT1 Mutation
Journal of the Korean Child Neurology Society(대한소아신경학회지) 25/3 :169-173,2017
Discontinuing Antiepileptic Drugs after Pediatric Epilepsy Surgery for Focal Cortical Dysplasia
Journal of the Korean Child Neurology Society(대한소아신경학회지) 25/3 :127-132,2017
Low glycemic index treatment in patients with drug-resistant epilepsy
BRAIN & DEVELOPMENT 39/8 :687-692,2017
Mowat-Wilson syndrome presenting with fever-associated seizures.
EPILEPTIC DISORDERS 19/4 :481-485,2017
Generation of two induced pluripotent stem cell (iPSC) lines from X-linked adrenoleukodystrophy (X-ALD) patients with adrenomyeloneuropathy (AMN)
STEM CELL RESEARCH 25/ :46-49,2017
Alpers-Huttenlocher Syndrome First Presented with Hepatic Failure: Can Liver Transplantation Be Considered as Treatment Option?
Pediatric Gastroenterology, Hepatology & Nutrition 20/4 :259-262,2017
Efficacy of Stiripentol in Dravet Syndrome with or without SCN1A Mutations
JOURNAL OF CLINICAL NEUROLOGY 14/1 :22-28,2018
Efficient strategy for the molecular diagnosis of intractable early-onset epilepsy using targeted gene sequencing
BMC MEDICAL GENOMICS 11/1 :6-,2018
Targeted gene panel and genotype-phenotype correlation in children with developmental and epileptic encephalopathy
EPILEPSY RESEARCH 141/ :48-55,2018
Differential effects on sodium current impairments by distinct SCN1A mutations in GABAergic neurons derived from Dravet syndrome patients
BRAIN & DEVELOPMENT 40/4 :287-298,2018
Vigabatrin and high-dose prednisolone therapy for patients with West syndrome
EPILEPSY RESEARCH 145/1 :127-133,2018
Adverse Events During Perampanel Adjunctive Therapy in Intractable Epilepsy
JOURNAL OF CLINICAL NEUROLOGY 14/3 :296-302,2018
Optimal clinical management of children receiving dietary therapies for epilepsy: Updated recommendations of the International Ketogenic Diet Study Group
EPILEPSIA 3/2 :175-192,2018
The efficacy of ketogenic diet for specific genetic mutation in developmental and epileptic encephalopathy
FRONTIERS IN NEUROLOGY 9/JUL :530-538,2018
Three-dimensional brain-like microenvironments facilitate the direct reprogramming of fibroblasts into therapeutic neurons
Nature biomedical engineering 2/7 :522-539,2018
Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination
NEURON 99/1 :83-97,2018
Interregional metabolic connectivity of 2-deoxy-2[18 F]fluoro-D-glucose positron emission tomography in vagus nerve stimulation for pediatric patients with epilepsy: A retrospective cross-sectional study.
EPILEPSIA 59/12 :2,249-2,259,2018
Early Diagnosis of KBG Syndrome Using Diagnostic Exome Sequencing
Journal of the Korean Child Neurology Society(대한소아신경학회지) 26/4 :272-275,2018
Brain somatic mutations in SLC35A2 cause intractable epilepsy with aberrant N-glycosylation
Neurology: Genetics 4/6 :e294-e302,2018
Long-term Outcome of Resective Epilepsy Surgery in Patients With Lennox-Gastaut Syndrome
PEDIATRICS 142/4 :e20180449-e20180459,2018
Age-Based Characteristics of West Syndrome in Patients with Mitochondrial Disease
Journal of the Korean Child Neurology Society(대한소아신경학회지) 26/4 :197-204,2018
Rufinamide efficacy and safety in children aged 1-4?years with Lennox-Gastaut syndrome
BRAIN & DEVELOPMENT 40/10 :897-903,2018
BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors
NATURE MEDICINE 24/11 :1,662-1,668,2018
Epilepsy Surgery for Children With Low-Grade Epilepsy-Associated Tumors: Factors Associated With Seizure Recurrence and Cognitive Function
PEDIATRIC NEUROLOGY 91/ :50-56,2019
Medication self-management and the quality of discharge education among parents of children with epilepsy
EPILEPSY & BEHAVIOR 94/5 :14-19,2019
Aligned Brain Extracellular Matrix Promotes Differentiation and Myelination of Human-Induced Pluripotent Stem Cell-Derived Oligodendrocytes
ACS APPLIED MATERIALS & INTERFACES 11/17 :15,344-15,353,2019
The use of technical replication for detection of low-level somatic mutations in next-generation sequencing
NATURE COMMUNICATIONS 10/1 :1047-,2019
A Child With Lymphangioma Due to Somatic Mutation in PIK3CA Successfully Treated With Everolimus
PEDIATRIC NEUROLOGY 91/ :65-67,2019
Clobazam as an adjunctive treatment for infantile spasms
EPILEPSY & BEHAVIOR 95/ :161-165,2019
Short- and long-term seizure-free outcomes of dietary treatment in infants according to etiology
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY 71/ :100-104,2019
Optimized Treatment for Infantile Spasms: Vigabatrin versus Prednisolone versus Combination Therapy
Journal of Clinical Medicine 8/10 :1591-1-1591-10,2019
Proband-Only Clinical Exome Sequencing for Neurodevelopmental Disabilities
PEDIATRIC NEUROLOGY 99/ :47-54,2019
Clinical Implementation of Targeted Gene Sequencing for Malformation of Cortical Development
PEDIATRIC NEUROLOGY 99/ :47-54,2019
Genetic and clinical features of SCN8A developmental and epileptic encephalopathy
EPILEPSY RESEARCH 158/1 :e106222-,2019
Precise detection of low-level somatic mutation in resected epilepsy brain tissue.
ACTA NEUROPATHOLOGICA 138/6 :901-912,2019
Brain somatic mutations in MTOR reveal translational dysregulations underlying intractable focal epilepsy
JOURNAL OF CLINICAL INVESTIGATION 129/10 :4,207-4,223,2019
저서
저서 내용이 없습니다.
보도자료
KAIST, 뇌전증 동반 소아 뇌종양 근본원인 밝혀
https://news.naver.com/main/read.nhn?mode=LSD&mid=sec&sid1=102&oid=030&aid=0002742050
KAIST, 난치성 뇌전증의 새로운 유전자 진단법 개발
https://www.sedaily.com/NewsView/1VMYDCMOVX
'난치성 뇌전증 원인 돌연변이' 더 정확히 분석한다
https://www.yna.co.kr/view/AKR20190813039600063?input=1195m
https://news.naver.com/main/read.nhn?mode=LSD&mid=sec&sid1=102&oid=030&aid=0002742050
KAIST, 난치성 뇌전증의 새로운 유전자 진단법 개발
https://www.sedaily.com/NewsView/1VMYDCMOVX
'난치성 뇌전증 원인 돌연변이' 더 정확히 분석한다
https://www.yna.co.kr/view/AKR20190813039600063?input=1195m
포스팅
포스팅 내용이 없습니다.
영상자료
영상자료 내용이 없습니다.
발표자료
발표자료 내용이 없습니다.