정혜원

임상조교수대우
  #임상약리학과

학력

~ 2012 : 고려대학교 의과대학 의학사
~ 2018 : 서울대학교 대학원 의학박사

경력

2012 .03 ~ 2013 .02 : 서울대학교병원 수련의
2013 .03 ~ 2017 .02 : 서울대학교병원 임상약리학과 연수의사
2017 .03 ~ 2019 .02 : 고려대학교구로병원 임상약리학과 임상강사
2019 .03 ~ : 고려대학교구로병원 임상약리학과 임상조교수대우

논문

[SCI] (Inhibition of the multidrug and toxin extrusion (MATE) transporter by pyrimethamine increases the plasma concentration of metformin but does not increase antihyperglycaemic activity in humans. Diabetes, Obesity and Metabolism.
2016;18(1):104-108)

[SCI] (Pharmacokinetics, Safety, and Tolerability of Metformin in Healthy Elderly Subjects. Journal of Clinical Pharmacology. 2016;56(9):1104-1110)

[SCI] (A thorough QT study to evaluate the QTc prolongation potential of two neuropsychiatric drugs, quetiapine and escitalopram, in healthy volunteers. International Clinical Psychopharmacology. 2016;31(4):210-217)

[SCI] (Pharmacokinetics and safety of a single dose of the novel necrosis inhibitor LC28-0126 in healthy male subjects. British Journal of Clinical Pharmacology. 2017;83(6):1205-1215)

[SCI] (A randomized, double-blind, single-dose, two-arm, parallel study comparing pharmacokinetics, immunogenicity and tolerability of branded adalimumab and its biosimilar LBAL in healthy male volunteers. Expert Opinion on Investigational Drugs. 2017;26(5):619-624)

[SCI] (LBEC0101, A Proposed Etanercept Biosimilar: Pharmacokinetics, Immunogenicity, and Tolerability Profiles Compared with a Reference Biologic Product in Healthy Male Subjects. BioDrugs. 2017;31(4):349-355)

[SCI] (A pharmacokinetic comparison of two voriconazole formulations and the effect of CYP2C19 polymorphism on their pharmacokinetic profiles. Drug Design, Development and Therapy. 2015;9:2609-2616)

[SCI] (Pharmacokinetics and effect on the corrected QT interval of single-dose escitalopram in healthy elderly compared with younger adults. International Clinical Psychopharmacology. 2017;32(1):20-26)

[SCI] (Physiologically Based Pharmacokinetic Modelling and Prediction of Metformin Pharmacokinetics in Renal/Hepatic-Impaired Young Adults and Elderly Populations. European Journal of Drug Metabolism and Pharmacokinetics. 2017;42(6):973-980)

[SCI] (A significant influence of metronidazole on busulfan pharmacokinetics: A case report of therapeutic drug monitoring. Therapeutic Drug Monitoring. 2017;39(3):208-210)

[SCI] (A non-linear pharmacokinetic-pharmacodynamic relationship of metformin in healthy volunteers: An open-label, parallel group, randomized clinical study. PLoS One. 2018;13(1):e0191258)

[SCI] (Pharmacokinetics of fludarabine and its association with clinical outcomes in paediatric haematopoietic stem cell transplantation patients)

[SCI] (Pharmacokinetics of Ursodeoxycholic Acid in Elderly Volunteers Compared With Younger Adults in a Korean Population)

[SCI] (Ursodeoxycholic acid exerts hepatoprotective effects by regulating amino acid, flavonoid, and fatty acid metabolic pathways)

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