안영근
#협심증#심근경색증#동맥경화증#심부전
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학력
1989. 전남대학교 의과대학 졸업
1998. 전남대학교 의학박사
2000. ~ 2002. 박사 후 연구원 (하바드의대 메사츄세츠병원)
1998. 전남대학교 의학박사
2000. ~ 2002. 박사 후 연구원 (하바드의대 메사츄세츠병원)
경력
1994. 내과전문의
1997. - 1998. 전남대학교병원 순환기내과 전임의
1998. - 2002. 전남대학교병원 임상전임강사, 임상조교수
2000. - 2002. 미국 하바드의대 박사 후 연구원
2004. - 2007. 전남대학교 의과대학 조교수
2007. - 2013. 전남대학교 의과대학 부교수
2013. - 현재 전남대학교 의과대학 교수
2006. ~ 2013 전남대학교 순환기내과장
2010. - 2012. 보건복지부 권역심혈관센터장
2012. ~ 2015. 보건복지부 권역심뇌혈관센터장
2014. ~ 2016. 진료지원실장, 국제메디컬센터장, 의무기록실장, 진료협력센터장
2016. ~ 2017. 기획조정실장
세포재생연구 센터장 (www.reheart.co.kr)
광주 - 보스톤 심포지움 director
광주 국제 심혈관 중재 심포지움 director
1997. - 1998. 전남대학교병원 순환기내과 전임의
1998. - 2002. 전남대학교병원 임상전임강사, 임상조교수
2000. - 2002. 미국 하바드의대 박사 후 연구원
2004. - 2007. 전남대학교 의과대학 조교수
2007. - 2013. 전남대학교 의과대학 부교수
2013. - 현재 전남대학교 의과대학 교수
2006. ~ 2013 전남대학교 순환기내과장
2010. - 2012. 보건복지부 권역심혈관센터장
2012. ~ 2015. 보건복지부 권역심뇌혈관센터장
2014. ~ 2016. 진료지원실장, 국제메디컬센터장, 의무기록실장, 진료협력센터장
2016. ~ 2017. 기획조정실장
세포재생연구 센터장 (www.reheart.co.kr)
광주 - 보스톤 심포지움 director
광주 국제 심혈관 중재 심포지움 director
논문
24. Lim SY, Kim YS, Ahn Y, Jeong MH, Hong MH, Joo SY, Nam KI, Cho JG, Kang PM, Park JC. The effects of mesenchymal stem cells transduced with Akt in a porcine myocardial infarction model. Cardiovasc Res. 2006;70:530-42.
23. Kee HJ, Sohn IS, Nam KI, Park JE, Qian YR, Yin Z, Ahn Y, Jeong MH, Bang YJ, Kim N, Kim JK, Kim KK, Epstein JA, Kook H. Inhibition of histone deacetylation blocks cardiac hypertrophy induced by angiotensin II infusion and aortic banding. Circulation. 2006;113:51-9.
22. Kim W, Jeong MH, Kim KH, Sohn IS, Hong YJ, Park HW, Kim JH, Ahn YK, Cho JG, Park JC, Cho DL, Kang JC. The clinical results of a platelet glycoprotein IIb/IIIa receptor blocker (abciximab: ReoPro)-coated stent in acute myocardial infarction. J Am Coll Cardiol. 2006;47:933-8.
21. Lim SY, Kim YS, Ahn Y, Jeong MH, Rok LS, Kim JH, Kim KH, Park HW, Kim W, Cho JG, Park JC, Kang PM, Schwartz RS, Kang JC. The effects of granulocyte-colony stimulating factor in bare stent and sirolimus-eluting stent in pigs following myocardial infarction. Int J Cardiol. 2007;118:304-11.
20. MH, Kim WJ, Jo S, Pun SH, Cho JG, Park JC, Kang JC, Ahn Y. Enhanced angiogenesis mediated by vascular endothelial growth factor plasmid-loaded thermo-responsive amphiphilic polymer in a rat myocardial infarction model. J Control Release. 2009;138:168-76.
19. Chen KY, Rha SW, Li YJ, Poddar KL, Jin Z, Minami Y, Wang L, Kim EJ, Park CG, Seo HS, Oh DJ, Jeong MH, Ahn YK, Hong TJ, Kim YJ, Hur SH, Seong IW, Chae JK, Cho MC, Bae JH, Choi DH, Jang YS, Chae IH, Kim CJ, Yoon JH, Chung WS, Seung KB, Park SJ; Korea Acute Myocardial Infarction Registry Investigators. Triple versus dual antiplatelet therapy in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Circulation. 2009;119:3207-14.
18. Hong YJ, Jeong MH, Choi YH, Ko JS, Lee MG, Kang WY, Lee SE, Kim SH, Park KH, Sim DS, Yoon NS, Youn HJ, Kim KH, Park HW, Kim JH, Ahn Y, Cho JG, Park JC, Kang JC. Impact of plaque components on no-reflow phenomenon after stent deployment in patients with acute coronary syndrome: a virtual histology-intravascular ultrasound analysis. Eur Heart J. 2011;32:2059-66.
17. Lee KH, Jeong MH, Kim HM, Ahn Y, Kim JH, Chae SC, Kim YJ, Hur SH, Seong IW, Hong TJ, Choi DH, Cho MC, Kim CJ, Seung KB, Chung WS, Jang YS, Rha SW, Bae JH, Cho JG, Park SJ; KAMIR (Korea Acute Myocardial Infarction Registry) Investigators. Benefit of early statin therapy in patients with acute myocardial infarction who have extremely low low-density lipoprotein cholesterol. J Am Coll Cardiol. 2011;58:1664-71.
16. Kwon JS, Kim YS, Cho AS, Cho HH, Kim JS, Hong MH, Jeong SY, Jeong MH, Cho JG, Park JC, Kang JC, Ahn Y. The novel role of mast cells in the microenvironment of acute myocardial infarction. J Mol Cell Cardiol. 2011;50:814-25.
15. Kwon JS, Song SJ, Yang EJ, Kim YS, Lim KS, Kim DG, Cho DL, Jeong MH, Ahn Y. Novel abciximab-Kruppel-like factor 4-plasmid dual-delivery titanium dioxide-coated coronary stent. Int J Cardiol. 2013;168:5104-6.
14. Kim YS, Kang WS, Kwon JS, Hong MH, Jeong HY, Jeong HC, Jeong MH, Ahn Y. Protective role of 5-azacytidine on myocardial infarction is associated with modulation of macrophage phenotype and inhibition of fibrosis. J Cell Mol Med. 2014;18:1018-27.
13. Kang WS, Kwon JS, Kim HB, Jeong HY, Kang HJ, Jeong MH, Cho JG, Park JC, Kim YS, Ahn Y. A macrophage-specific synthetic promoter for therapeutic application of adiponectin. Gene Ther. 2014;21:353-62.
12. Cho DI, Kim MR, Jeong HY, Jeong HC, Jeong MH, Yoon SH, Kim YS, Ahn Y. Mesenchymal stem cells reciprocally regulate the M1/M2 balance in mouse bone marrow-derived macrophages. Exp Mol Med. 2014;46:e70.
11. Nam YS, Kim Y, Joung H, Kwon DH, Choe N, Min HK, Kim YS, Kim HS, Kim DK, Cho YK, Kim YH, Nam KI, Choi HC, Park DH, Suk K, Lee IK, Ahn Y, Lee CH, Choi HS, Eom GH, Kook H. Small heterodimer partner blocks cardiac hypertrophy by interfering with GATA6 signaling. Circ Res. 2014;115:493-503.
10. Kang HJ, Kang WS, Hong MH, Choe N, Kook H, Jeong HC, Kang J, Hur J, Jeong MH, Kim YS, Ahn Y. Involvement of miR-34c in high glucose-insulted mesenchymal stem cells leads to inefficient therapeutic effect on myocardial infarction. Cell Signal. 2015;27:2241-51.
9. Kim MC, Cho JY, Jeong HC, Lee KH, Park KH, Sim DS, Yoon NS, Yoon HJ, Kim KH, Hong YJ, Park HW, Kim JH, Jeong MH, Cho JG, Park JC, Seung KB, Chang K, Ahn Y. Impact of postdischarge statin withdrawal on long-term outcomes in patients with acute myocardial infarction. Am J Cardiol. 2015;115:1-7.
8. Park J, Kim YS, Ryu S, Kang WS, Park S, Han J, Jeong HC, Hong BH, Ahn Y, Kim BS. Graphene Potentiates the Myocardial Repair Efficacy of Mesenchymal Stem Cells by Stimulating the Expression of Angiogenic Growth Factors and Gap Junction Protein. Advanced Functional Materials. 2015;25:2590-2600.
7. Jeong HY, Kang WS, Hong MH, Jeong HC, Shin MG, Jeong MH, Kim YS, Ahn Y. 5-Azacytidine modulates interferon regulatory factor 1 in macrophages to exert a cardioprotective effect. Sci Rep. 2015;5:15768.
6. Kwon DH, Eom GH, Ko JH, Shin S, Joung H, Choe N, Nam YS, Min HK, Kook T, Yoon S, Kang W, Kim YS, Kim HS, Choi H, Koh JT, Kim N, Ahn Y, Cho HJ, Lee IK, Park DH, Suk K, Seo SB, Wissing ER, Mendrysa SM, Nam KI, Kook H. MDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification. Nat Commun. 2016;7:10492.
5. Sim DS, Jeong MH, Ahn Y, Kim YJ, Chae SC, Hong TJ, Seong IW, Chae JK, Kim CJ, Cho MC, Rha SW, Bae JH, Seung KB, Park SJ; Korea Acute Myocardial Infarction Registry (KAMIR) Investigators. Pharmacoinvasive Strategy Versus Primary Percutaneous Coronary Intervention in Patients With ST-Segment-Elevation Myocardial Infarction: A Propensity Score-Matched Analysis. Circ Cardiovasc Interv. 2016;9:e003508.
4. Kim YS, Jeong HY, Kim AR, Kim WH, Cho H, Um J, Seo Y, Kang WS, Jin SW, Kim MC, Kim YC, Jung DW, Williams DR, Ahn Y. Natural product derivative BIO promotes recovery after myocardial infarction via unique modulation of the cardiac microenvironment. Sci Rep. 2016;6:30726.
3. Kim MC, Ahn Y, Sim DS, Hong YJ, Kim JH, Jeong MH, Gwon HC, Kim HS, Rha SW, Yoon JH, Jang Y, Tahk SJ, Seung KB. Impact of calcified bifurcation lesions in patients undergoing percutaneous coronary intervention using drug-eluting stents: results from the COronary BIfurcation Stent (COBIS) II registry. EuroIntervention. 2017;13:338-344.
2. Kim MC, Kim YS, Kang WS, Lee KH, Cho M, Hong MH, Lim KS, Jeong MH, Ahn Y. Intramyocardial Injection of Stem Cells in Pig Myocardial Infarction Model: The First Trial in Korea. J Korean Med Sci. 2017;32:1708-1712 (cover page).
1. Cho DI, Kang WS, Hong MH, Kang HJ, Kim MR, Kim MC, Kim YS, Ahn Y. The optimization of cell therapy by combinational application with apicidin-treated mesenchymal stem cells after myocardial infarction. Oncotarget. 2017;8:44281-44294.
23. Kee HJ, Sohn IS, Nam KI, Park JE, Qian YR, Yin Z, Ahn Y, Jeong MH, Bang YJ, Kim N, Kim JK, Kim KK, Epstein JA, Kook H. Inhibition of histone deacetylation blocks cardiac hypertrophy induced by angiotensin II infusion and aortic banding. Circulation. 2006;113:51-9.
22. Kim W, Jeong MH, Kim KH, Sohn IS, Hong YJ, Park HW, Kim JH, Ahn YK, Cho JG, Park JC, Cho DL, Kang JC. The clinical results of a platelet glycoprotein IIb/IIIa receptor blocker (abciximab: ReoPro)-coated stent in acute myocardial infarction. J Am Coll Cardiol. 2006;47:933-8.
21. Lim SY, Kim YS, Ahn Y, Jeong MH, Rok LS, Kim JH, Kim KH, Park HW, Kim W, Cho JG, Park JC, Kang PM, Schwartz RS, Kang JC. The effects of granulocyte-colony stimulating factor in bare stent and sirolimus-eluting stent in pigs following myocardial infarction. Int J Cardiol. 2007;118:304-11.
20. MH, Kim WJ, Jo S, Pun SH, Cho JG, Park JC, Kang JC, Ahn Y. Enhanced angiogenesis mediated by vascular endothelial growth factor plasmid-loaded thermo-responsive amphiphilic polymer in a rat myocardial infarction model. J Control Release. 2009;138:168-76.
19. Chen KY, Rha SW, Li YJ, Poddar KL, Jin Z, Minami Y, Wang L, Kim EJ, Park CG, Seo HS, Oh DJ, Jeong MH, Ahn YK, Hong TJ, Kim YJ, Hur SH, Seong IW, Chae JK, Cho MC, Bae JH, Choi DH, Jang YS, Chae IH, Kim CJ, Yoon JH, Chung WS, Seung KB, Park SJ; Korea Acute Myocardial Infarction Registry Investigators. Triple versus dual antiplatelet therapy in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Circulation. 2009;119:3207-14.
18. Hong YJ, Jeong MH, Choi YH, Ko JS, Lee MG, Kang WY, Lee SE, Kim SH, Park KH, Sim DS, Yoon NS, Youn HJ, Kim KH, Park HW, Kim JH, Ahn Y, Cho JG, Park JC, Kang JC. Impact of plaque components on no-reflow phenomenon after stent deployment in patients with acute coronary syndrome: a virtual histology-intravascular ultrasound analysis. Eur Heart J. 2011;32:2059-66.
17. Lee KH, Jeong MH, Kim HM, Ahn Y, Kim JH, Chae SC, Kim YJ, Hur SH, Seong IW, Hong TJ, Choi DH, Cho MC, Kim CJ, Seung KB, Chung WS, Jang YS, Rha SW, Bae JH, Cho JG, Park SJ; KAMIR (Korea Acute Myocardial Infarction Registry) Investigators. Benefit of early statin therapy in patients with acute myocardial infarction who have extremely low low-density lipoprotein cholesterol. J Am Coll Cardiol. 2011;58:1664-71.
16. Kwon JS, Kim YS, Cho AS, Cho HH, Kim JS, Hong MH, Jeong SY, Jeong MH, Cho JG, Park JC, Kang JC, Ahn Y. The novel role of mast cells in the microenvironment of acute myocardial infarction. J Mol Cell Cardiol. 2011;50:814-25.
15. Kwon JS, Song SJ, Yang EJ, Kim YS, Lim KS, Kim DG, Cho DL, Jeong MH, Ahn Y. Novel abciximab-Kruppel-like factor 4-plasmid dual-delivery titanium dioxide-coated coronary stent. Int J Cardiol. 2013;168:5104-6.
14. Kim YS, Kang WS, Kwon JS, Hong MH, Jeong HY, Jeong HC, Jeong MH, Ahn Y. Protective role of 5-azacytidine on myocardial infarction is associated with modulation of macrophage phenotype and inhibition of fibrosis. J Cell Mol Med. 2014;18:1018-27.
13. Kang WS, Kwon JS, Kim HB, Jeong HY, Kang HJ, Jeong MH, Cho JG, Park JC, Kim YS, Ahn Y. A macrophage-specific synthetic promoter for therapeutic application of adiponectin. Gene Ther. 2014;21:353-62.
12. Cho DI, Kim MR, Jeong HY, Jeong HC, Jeong MH, Yoon SH, Kim YS, Ahn Y. Mesenchymal stem cells reciprocally regulate the M1/M2 balance in mouse bone marrow-derived macrophages. Exp Mol Med. 2014;46:e70.
11. Nam YS, Kim Y, Joung H, Kwon DH, Choe N, Min HK, Kim YS, Kim HS, Kim DK, Cho YK, Kim YH, Nam KI, Choi HC, Park DH, Suk K, Lee IK, Ahn Y, Lee CH, Choi HS, Eom GH, Kook H. Small heterodimer partner blocks cardiac hypertrophy by interfering with GATA6 signaling. Circ Res. 2014;115:493-503.
10. Kang HJ, Kang WS, Hong MH, Choe N, Kook H, Jeong HC, Kang J, Hur J, Jeong MH, Kim YS, Ahn Y. Involvement of miR-34c in high glucose-insulted mesenchymal stem cells leads to inefficient therapeutic effect on myocardial infarction. Cell Signal. 2015;27:2241-51.
9. Kim MC, Cho JY, Jeong HC, Lee KH, Park KH, Sim DS, Yoon NS, Yoon HJ, Kim KH, Hong YJ, Park HW, Kim JH, Jeong MH, Cho JG, Park JC, Seung KB, Chang K, Ahn Y. Impact of postdischarge statin withdrawal on long-term outcomes in patients with acute myocardial infarction. Am J Cardiol. 2015;115:1-7.
8. Park J, Kim YS, Ryu S, Kang WS, Park S, Han J, Jeong HC, Hong BH, Ahn Y, Kim BS. Graphene Potentiates the Myocardial Repair Efficacy of Mesenchymal Stem Cells by Stimulating the Expression of Angiogenic Growth Factors and Gap Junction Protein. Advanced Functional Materials. 2015;25:2590-2600.
7. Jeong HY, Kang WS, Hong MH, Jeong HC, Shin MG, Jeong MH, Kim YS, Ahn Y. 5-Azacytidine modulates interferon regulatory factor 1 in macrophages to exert a cardioprotective effect. Sci Rep. 2015;5:15768.
6. Kwon DH, Eom GH, Ko JH, Shin S, Joung H, Choe N, Nam YS, Min HK, Kook T, Yoon S, Kang W, Kim YS, Kim HS, Choi H, Koh JT, Kim N, Ahn Y, Cho HJ, Lee IK, Park DH, Suk K, Seo SB, Wissing ER, Mendrysa SM, Nam KI, Kook H. MDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification. Nat Commun. 2016;7:10492.
5. Sim DS, Jeong MH, Ahn Y, Kim YJ, Chae SC, Hong TJ, Seong IW, Chae JK, Kim CJ, Cho MC, Rha SW, Bae JH, Seung KB, Park SJ; Korea Acute Myocardial Infarction Registry (KAMIR) Investigators. Pharmacoinvasive Strategy Versus Primary Percutaneous Coronary Intervention in Patients With ST-Segment-Elevation Myocardial Infarction: A Propensity Score-Matched Analysis. Circ Cardiovasc Interv. 2016;9:e003508.
4. Kim YS, Jeong HY, Kim AR, Kim WH, Cho H, Um J, Seo Y, Kang WS, Jin SW, Kim MC, Kim YC, Jung DW, Williams DR, Ahn Y. Natural product derivative BIO promotes recovery after myocardial infarction via unique modulation of the cardiac microenvironment. Sci Rep. 2016;6:30726.
3. Kim MC, Ahn Y, Sim DS, Hong YJ, Kim JH, Jeong MH, Gwon HC, Kim HS, Rha SW, Yoon JH, Jang Y, Tahk SJ, Seung KB. Impact of calcified bifurcation lesions in patients undergoing percutaneous coronary intervention using drug-eluting stents: results from the COronary BIfurcation Stent (COBIS) II registry. EuroIntervention. 2017;13:338-344.
2. Kim MC, Kim YS, Kang WS, Lee KH, Cho M, Hong MH, Lim KS, Jeong MH, Ahn Y. Intramyocardial Injection of Stem Cells in Pig Myocardial Infarction Model: The First Trial in Korea. J Korean Med Sci. 2017;32:1708-1712 (cover page).
1. Cho DI, Kang WS, Hong MH, Kang HJ, Kim MR, Kim MC, Kim YS, Ahn Y. The optimization of cell therapy by combinational application with apicidin-treated mesenchymal stem cells after myocardial infarction. Oncotarget. 2017;8:44281-44294.
저서
골수성체줄기세포 치료의 현재와 미래. 재생의학의 현황과 육성방안. 한림연구보고서 97. 한국과학기술한림원 (978-89-92869-95-9) 외 28 편
보도자료
심혈관 질환 치료 줄기세포 안영근 교수 연구 장관 표창 / [광주일보] 2017-12-25
http://www.kwangju.co.kr/read.php3?aid=1514127600620393025
우즈벡 두 살배기 전남대병원 도움으로 새 삶 얻어 / [파이낸셜뉴스] 2017-12-12
http://www.fnnews.com/news/201712121255235644
전남대병원 안영근 교수, 자랑스러운 일고인상 수상 / [아시아경제] 2017-11-2
http://www.asiae.co.kr/news/view.htm?idxno=2017110207153796104
http://www.kwangju.co.kr/read.php3?aid=1514127600620393025
우즈벡 두 살배기 전남대병원 도움으로 새 삶 얻어 / [파이낸셜뉴스] 2017-12-12
http://www.fnnews.com/news/201712121255235644
전남대병원 안영근 교수, 자랑스러운 일고인상 수상 / [아시아경제] 2017-11-2
http://www.asiae.co.kr/news/view.htm?idxno=2017110207153796104
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발표자료
1. Ahn Y, Kim YS, Jeong HY, Jung DW, Williams DR. Composition comprising BIO compound for treating cardiovascular disease. US 9,757,356 (09/12/2017) 외 9 건