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교수
    

  #전립선암#비뇨기암#폐암#뇌종양#림프종#소아암#육종#헬스조선명의

학력

연세대학교 의과대학 의학사 (1988-1996)
연세대학교 의과대학 의학석사 (2000-2001)
연세대학교 의과대학 의학박사 (2003-2006)

경력

2004.03.~2013.02. 연세의대 방사선종양학과 전임강사, 조교수, 부교수
2015.03.~현재. 연세의대 방사선종양학과 정교수 (신촌세브란스, 연세암병원 근무)
---------------------------------------------
(교육 및 파견)
1996.03.~2004.02. 세브란스병원 수련의 및 방사선종양학 전공의, 강사
2001.09.~2003.04. 해외파견 - 미국 Washington University School of Medicine in St Louis
방사선종양학과 생물분과 연구원
2007.10.~2009.12. 해외출장 - 미국 University of Texas Southwestern Medical Center 방사선종양학과
분자방사선생물분과 방문교수 (연구출장)
2013.03.~2015.02. 국내파견 - 연세의대 (강남) 세브란스병원 방사선종양학과 과장

논문

Angiocentric lymphoma of the head and neck: Patterns of systemic failure after radiation treatment
JOURNAL OF CLINICAL ONCOLOGY 18/1 :54-63,2000
Preoperative chemoradiotherapy with oral doxifluridine plus low-dose oral leucovorin in unresectable primary rectal cancer
International journal of radiation oncology biol phys 50/2 :435-439,2001
Hyperfractionated Re-irradiation using a 3-Dimensional Conformal Technique for Locally recurrent carcinoma of the Nasopharynx; Preliminary Results.
YONSEI MEDICAL JOURNAL 42/1 :55-64,2001
근침윤성 방광암에서 화학방사선 병용을 통한 방광보존치료
대한방사선종양학회지(Journal Of The Korean Society For Therapeutic Radiology And Oncology) 19/4 :359-368,2001
복부 방사선치료를 받는 환자에서 발생하는 오심 및 구토에 대한 온단세트론과 메트클로프로파마이드의 효과 : 제 3상 전향적 무작위 임상비교시험
대한방사선종양학회지(Journal Of The Korean Society For Therapeutic Radiology And Oncology) 19/2 :127-135,2001
Improved breast irradiation techniques using multistatic fields or three dimensional universal compensators
대한방사선종양학회지(journalofthekoreansocietyfortherapeuticradiologyandoncology) 20/1 :24-33,2002
유방전절제술 후 방사선치료를 위한 조직보상체 개발 및 3차원 치료계획을 통한 유용성 분석
대한방사선종양학회지(Journal Of The Korean Society For Therapeutic Radiology And Oncology) 21/1 :82-93,2003
3차원 입체조형치료에 의한 아교모세포종의 방사선 선량증가 연구
대한방사선종양학회지(Journal Of The Korean Society For Therapeutic Radiology And Oncology) 22/4 :237-246,2004
수모세포종의 방사선치료 후 전두엽하방재발된 환자에서 원인 분석 및 구제 치료
대한방사선종양학회지(Journal Of The Korean Society For Therapeutic Radiology And Oncology) 22/3 :165-176,2004
전립선암에 대한 방사선치료
대한의사협회지(Journal Of The Korean Medical Association) / :424-431,2004
후방 골간 신경 마비의 치료
대한정형외과학회지 39/2 :198-202,2004
Apoptosis and proliferation in paired primary colorectal adenocarcinomas and their liver metastases
YONSEI MEDICAL JOURNAL 45/ :187-192,2004
Lack of correlation between P-glycoprotein and chemotherapy resistance in nasal NK/T-cell lymphomas
LEUKEMIA & LYMPHOMA 45/9 :1857-1864,2004
1998, 1999년도 우리나라에서 시행된 유방보존수술 후 방사선치료 현황 조사
대한방사선종양학회지(Journal Of The Korean Society For Therapeutic Radiology And Oncology) 22/3 :192-199,2004
처방선량 및 치료기법별 치료성적 분석 결과에 기반한 자궁경부암 환자의 최적 방사선치료 스케쥴
대한방사선종양학회지(Journal Of The Korean Society For Therapeutic Radiology And Oncology) 23/3 :143-156,2005
The role of postoperative external-beam radiotherapy in the management of patients with papillary thyroid cancer invading the trachea
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 65/2 :474-480,2006
병리학적 병기 T3 방광이행세포암에서 신보조적 체외 방사선치료의 효과
Korean Journal of Urology 47/3 :232-236,2006
Predictive value of p53 and PCNA expression for occult neck metastases in patients with clinically node-negative oral tongue cancer
OTOLARYNGOLOGY-HEAD AND NECK SURGERY 135/6 :858-864,2006
Role of p53 in antioxidant defense of HPV-positive cervical carcinoma cells following H
JOURNAL OF CELL SCIENCE 120/13 :2284-2294,2007
Concurrent chemoradiotherapy followed by adjuvant chemotherapy in uterine cervical cancer patients with high-risk factors
GYNECOLOGIC ONCOLOGY 104/1 :58-63,2007
Treatment failure in intracranial primary germinomas
CHILDS NERVOUS SYSTEM 23/ :1155-1161,2007
Clinical significance of cyclooxygenase-2 expression in extranodal natural killer (NK)/T-cell lymphoma, nasal type
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 67/1 :31-38,2007
Perspectives of Radiotherapy and Combined Modality Treatment
대한비뇨기종양학회지(The korean Journal of Urological Oncology) 5/1 :88-93,2007
The effect of respiratory motion on forward intensity modulated radiotherapy for breast cancer
Technology In Cancer Research & Treatment 7/ :207-215,2008
Patterns of Care Study를 위한 2006년 한국 방사선종양학과 전문의들의 전립선암 방사선치료원칙 조사연구
대한방사선종양학회지(Journal Of The Korean Society For Therapeutic Radiology And Oncology) 26/2 :96-103,2008
사지에 발병한 카포시육종의 방사선치료를 위한 물볼루스 기구의 유용성 고찰
대한방사선종양학회지(Journal Of The Korean Society For Therapeutic Radiology And Oncology) 26/3 :189-194,2008
Hypofractionated high-dose intensity-modulated radiotherapy (60 Gy at 2.5 Gy per fraction) for recurrent renal cell carcinoma: A case report
Journal Of Korean Medical Science 23/ :740-743,2008
EARLY CLINICAL EXPERIENCE AND OUTCOME OF HELICAL TOMOTHERAPY FOR MULTIPLE METASTATIC LESIONS
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 73/ :1517-1524,2009
Low-dose craniospinal irradiation as a definitive treatment for intracranial germinoma
Radiotherapy And Oncology 91/ :75-79,2009
자궁목암종에서 Hypoxia Inducible Factor-1α의 발현과 Cyclin A1, Cyclin B1 발현 및 임상병리학적 인자들과의 연관성
Korean Journal Of Pathology(대한병리학회) 43/1 :13-19,2009
management of locally advanced non-small cell lung cancer
Journal Of Lung Cancer 8/1 :1-7,2009
Superficial Dosimetry for Helical Tomotherapy
Journal Of The Korean Society For Therapeutic Radiology And Oncology(대한방사선종양학회지) 27/2 :103-110,2009
Phase II Trial of Concurrent Radiation and Weekly Cisplatin Followed by VIPD Chemotherapy in Newly Diagnosed, Stage IE to IIE, Nasal, Extranodal NK/T-Cell Lymphoma: Consortium for Improving Survival of Lymphoma Study
Journal Of Clinical Oncology 27/35 :6027-6032,2009
Positional Reproducibility and Effects of a Rectal Balloon in Prostate Cancer Radiotherapy
Journal Of Korean Medical Science 24/5 :894-903,2009
High dose-per-fraction irradiation of limited lung volumes using an image-guided, highly focused irradiator: simulating stereotactic body radiotherapy regimens in a small-animal model
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 77/3 :895-902,2010
Pattern of Failure in Bladder Cancer Patients Treated with Radical Cystectomy: Rationale for Adjuvant Radiotherapy
JOURNAL OF KOREAN MEDICAL SCIENCE 25/ :835-840,2010
Is There a Clinical Benefit to Adaptive Planning During Tomotherapy in Patients with Head and Neck Cancer at Risk for Xerostomia?
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS 35/3 :261-266,2012
MGMT GENE PROMOTER METHYLATION AS A POTENT PROGNOSTIC FACTOR IN GLIOBLASTOMA TREATED WITH TEMOZOLOMIDE-BASED CHEMORADIOTHERAPY: A SINGLE INSTITUTION STUDY
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 84/3 :661-667,2012
A Multimodal Approach Including Craniospinal Irradiation Improves the Treatment Outcome of High-Risk Intracranial Nongerminomatous Germ Cell Tumors
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 84/3 :625-631,2012
Molecular Markers Predict Distant Metastases After Adjuvant Chemoradiation for Rectal Cancer
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 84/5 :e577-e584,2012
IMRT with Simultaneous Integrated Boost and Concurrent Chemotherapy for Nasopharyngeal Cancer: Plan Evaluation and Treatment Outcome
JAPANESE JOURNAL OF CLINICAL ONCOLOGY 42/12 :1152-1160,2012
Radiotherapy for solitary plasmacytoma of bone and soft tissue Outcomes and prognostic factors
ANNALS OF HEMATOLOGY 91/11 :1785-1793,2012
Treatment strategy for intracranial primary pure germinoma
CHILDS NERVOUS SYSTEM 29/2 :239-248,2013
A phase I trial of gefitinib and nimotuzumab in patients with advanced non-small cell lung cancer (NSCLC)
LUNG CANCER 79/3 :270-275,2013
Development of a porcine skin injury model and characterization of the dose-dependent response to high-dose radiation
JOURNAL OF RADIATION RESEARCH 54/ :823-831,2013
Early volumetric change and treatment outcome of metastatic brain tumors after external beam radiotherapy: differential radiotherapy for brain metastasis.
CLINICAL & TRANSLATIONAL ONCOLOGY 15/11 :889-896,2013
A Comparative Planning Study of Step-and-shoot IMRT versus Helical Tomotherapy in a Model Patient
JOURNAL OF THE KOREAN PHYSICAL SOCIETY 63/7 :1481-1485,2013
Patterns of care and treatment outcomes for primary thyroid lymphoma: a single institution study
Radiation oncology journal 31/4 :177-184,2013
Feasibility and Outcomes of Hypofractionated Simultaneous Integrated Boost-Intensity Modulated Radiotherapy for Malignant Gliomas: A Preliminary Report
YONSEI MEDICAL JOURNAL 55/1 :70-77,2014
A Preclinical Rodent Model of Acute Radiation-Induced Lung Injury after Ablative Focal Irradiation Reflecting Clinical Stereotactic Body Radiotherapy
RADIATION RESEARCH 182/1 :83-91,2014
Development of a small animal model to simulate clinical stereotactic body radiotherapy-induced central and peripheral lung injuries
JOURNAL OF RADIATION RESEARCH 55/4 :648-657,2014
Treatment outcome of localized prostate cancer by 70 Gy hypofractionated intensity-modulated radiotherapy with a customized rectal balloon
Radiation Oncology Journal 32/3 :187-197,2014
The role of radiotherapy in the management of POEMS syndrome
RADIATION ONCOLOGY 9/ :-,2014
Concurrent chemoradiotherapy followed by L-asparaginase-containing chemotherapy, VIDL, for localized nasal extranodal NK/T cell lymphoma: CISL08-01 phase II study
ANNALS OF HEMATOLOGY 93/11 :1895-1901,2014
Adjuvant Radiotherapy Outcome of Stage I Testicular Seminoma: A Single Institution Study
YONSEI MEDICAL JOURNAL 56/1 :24-30,2015
The inflammasome accelerates radiation-induced lung inflammation and fibrosis in mice
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 39/2 :917-926,2015
Pyruvate metabolism: A therapeutic opportunity in radiation-induced skin injury.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 460/3 :504-510,2015
An experimental model-based exploration of cytokines in ablative radiation-induced lung injury in vivo and in vitro.
LUNG 193/3 :409-419,2015
Successful salvage treatment of myxoid liposarcoma with multiple peritoneal seeding using helical tomotherapy-based intraperitoneal radiotherapy: a case report.
BMC Research Notes 8/179 :1-9,2015
Multi-institutional analysis of T3 subtypes and adjuvant radiotherapy effects in resected T3N0 non-small cell lung cancer patients
Radiation Oncology Journal 33/2 :75-82,2015
Single high-dose irradiation aggravates eosinophil-mediated fibrosis through IL-33 secreted from impaired vessels in the skin compared to fractionated irradiation
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 464/1 :20-26,2015
A Hypoxia-Induced Vascular Endothelial-to-Mesenchymal Transition in Development of Radiation-Induced Pulmonary Fibrosis.
CLINICAL CANCER RESEARCH 21/16 :3716-3726,2015
Pattern of care of anaplastic oligodendroglioma and oligoastrocytoma in a Korean population: the Korean radiation oncology group study 13-12
JOURNAL OF NEURO-ONCOLOGY 121/3 :531-539,2015
A multicenter study of anaplastic oligodendroglioma: the Korean Radiation Oncology Group Study 13-12
JOURNAL OF NEURO-ONCOLOGY 125/1 :207-215,2015
Patterns of Failure Following Multimodal Treatment for Medulloblastoma: Long-Term Follow-up Results at a Single Institution
CANCER RESEARCH AND TREATMENT 47/4 :879-888,2015
Radiotherapy as an effective treatment modality for follicular lymphoma: a single institution experience
Radiation Oncology Journal 33/4 :310-319,2015
Early treatment volume reduction rate as a prognostic factor in patients treated with chemoradiotherapy for limited stage small cell lung cancer
Radiation Oncology Journal 33/2 :117-125,2015
Does Radiotherapy for the Primary Tumor Benefit Prostate Cancer Patients with Distant Metastasis at Initial Diagnosis?
PLOS ONE 11/1 :e014791-,2016
Focal exposure of limited lung volumes to high-dose irradiation down-regulated organ development-related functions and up-regulated the immune response in mouse pulmonary tissues.
BMC GENETICS 17/29 :1-21,2016
Pseudoprogression in glioblastoma patients: the impact of extent of resection
JOURNAL OF NEURO-ONCOLOGY 126/3 :559-566,2016
Time, Dose, and Volume Responses in a Mouse Pulmonary Injury Model Following Ablative Irradiation
LUNG 194/1 :81-90,2016
Hippocampus-Sparing Whole-Brain Radiotherapy and Simultaneous Integrated Boost for Multiple Brain Metastases From Lung Adenocarcinoma: Early Response and Dosimetric Evaluation.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT 15/1 :122-129,2016
Evolving Clinical Cancer Radiotherapy: Concerns Regarding Normal Tissue Protection and Quality Assurance
JOURNAL OF KOREAN MEDICAL SCIENCE 31/Suppl :S75-S87,2016
Mechanical quality assurance using light field for linear accelerators with camera calibration
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS 32/ :398-402,2016
HSPB1 Inhibits the Endothelial-to-Mesenchymal Transition to Suppress Pulmonary Fibrosis and Lung Tumorigenesis.
CANCER RESEARCH 76/6 :1019-30,2016
Treatment Outcome and Prognostic Molecular Markers of Supratentorial Primitive Neuroectodermal Tumors
PLOS ONE 11/4 :e0153443-,2016
Regulatory T Cells Contribute to the Inhibition of Radiation-Induced Acute Lung Inflammation via Bee Venom Phospholipase A₂ in Mice.
TOXINS 8/5 :E131-,2016
Re-Irradiation for Recurrent Gliomas:Treatment Outcomes and Prognostic Factors
YONSEI MEDICAL JOURNAL 57/4 :824-830,2016
The roles of Radiotherapy and Chemotherapy in the Era of Multimodal Treatment for Early-Stage Nasal-Type Externodal Natural Killer/T-Cell Lymphoma
YONSEI MEDICAL JOURNAL 57/4 :846-854,2016
Induction of miR-21 by stereotactic body radiotherapy contributes to the pulmonary fibrotic response
PLOS ONE 11/5 :e0154942-,2016
중추신경계 생식세포종양의 최근 치료 경향
Clinical Pediatric Hematology-Oncology 23/1 :17-27,2016
Identification of radiation response genes and proteins from mouse pulmonary tissues after high-dose per fraction irradiation of limited lung volumes
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 93/2 :184-193,2017
Impact of including peritumoral edema in radiotherapy target volume on patterns of failure in glioblastoma following temozolomide-based chemoradiotherapy
SCIENTIFIC REPORTS 7/42148 :1-9,2017
Pro-apoptotic Noxa is involved in ablative focal irradiation-induced lung injury.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 21/4 :711-719,2017
Adenovirus-mediated Foxp3 expression in lung epithelial cells ameliorates acute radiation-induced pneumonitis in mice.
GENE THERAPY 24/2 :104-112,2017
Standardized Herbal Formula PM014 Inhibits Radiation-Induced Pulmonary Inflammation in Mice.
SCIENTIFIC REPORTS 7/ :45,001-,2017
Maximum surgical resection and adjuvant intensity-modulated radiotherapy with simultaneous integrated boost for skull base chordoma
ACTA NEUROCHIRURGICA 159/ :1825-1834,2017
Factors associated with pulmonary toxicity after myeloablative conditioning using fractionated total body irradiation
Radiation Oncology Journal 35/03 :257-267,2017
Role of radiation therapy in primary central nervous system lymphoma
JOURNAL OF NEURO-ONCOLOGY 135/3 :629-638,2017
Long-term outcomes of concomitant chemoradiotherapy with temozolomide for newly diagnosed glioblastoma patients A single-center analysis
MEDICINE 96/27 :e7422-,2017
Predictive factors of symptomatic radiation pneumonitis in primary and metastatic lung tumors treated with stereotactic ablative body radiotherapy
Radiation Oncology Journal 35/2 :163-171,2017
Recurrence patterns after maximal surgical resection and postoperative radiotherapy in anaplastic gliomas according to the new 2016 WHO classification
SCIENTIFIC REPORTS 8/ :777-1-777-9,2018
HSP27 inhibitor attenuates radiation-induced pulmonary inflammation
SCIENTIFIC REPORTS 8/1 :4,189-4,200,2018
Interobserver variation in target volume for salvage radiotherapy in recurrent prostate cancer patients after radical prostatectomy using CT versus combined CT and MRI: a multicenter study (KROG 13-11)
Radiation Oncology Journal 36/1 :11-16,2018
Metformin Alleviates Radiation-Induced Skin Fibrosis via the Downregulation of FOXO3
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY 48/3 :959-970,2018
Clinical outcomes of radiotherapy for spinal cord ependymoma with adverse prognostic features: a single-center study
JOURNAL OF NEURO-ONCOLOGY 140/3 :649-657,2018
Optimizing tissue-clearing conditions based on analysis of the critical factors affecting tissue-clearing procedures
SCIENTIFIC REPORTS 8/1 :12,815-12,825,2018
Development of an easy-to-handle murine model for the characterization of radiation-induced gross and molecular changes in skin
Archives of Plastic Surgery 45/5 :403-410,2018
Efficacy of Postoperative Radiotherapy Using Modern Techniques in Patients with Retroperitoneal Soft Tissue Sarcoma
YONSEI MEDICAL JOURNAL 59/9 :1,049-1,056,2018
Tumour-vasculature development via endothelial-to-mesenchymal transition after radiotherapy controls CD44v6+ cancer cell and macrophage polarization
NATURE COMMUNICATIONS 9/1 :5,108-5,125,2018
Treatment outcomes of radiotherapy for primary spinal cord glioma
STRAHLENTHERAPIE UND ONKOLOGIE 195/2 :164-174,2019
Clinical predictors of radiation-induced lymphopenia in patients receiving chemoradiation for glioblastoma: clinical usefulness of intensity-modulated radiotherapy in the immuno-oncology era
RADIATION ONCOLOGY 14/1 :51-60,2019
Identification of molecular signatures involved in radiation-induced lung fibrosis
JOURNAL OF MOLECULAR MEDICINE-JMM 97/1 :37-47,2019
A multi-institutional study of bladder-preserving therapy for stage II-IV bladder cancer: A Korean Radiation Oncology Group Study (KROG 14-16).
PLOS ONE 14/1 :e0209998-,2019
The Korean Society for Neuro-Oncology (KSNO) guideline for glioblastomas: version 2018.01
Brain Tumor Reserach and Treatment 7/1 :1-9,2019
Long-term outcome, relapse patterns, and toxicity after radiotherapy for orbital mucosaassociated lymphoid tissue lymphoma:implications for radiotherapy optimization
JAPANESE JOURNAL OF CLINICAL ONCOLOGY 49/7 :664-670,2019
Analysis of patterns of failure and appraisal of postoperative radiation field for grade II-III meningioma
JOURNAL OF NEURO-ONCOLOGY 144/2 :333-341,2019
The Hsp27-Mediated IkBα-NFκB Signaling Axis Promotes Radiation-Induced Lung Fibrosis.
CLINICAL CANCER RESEARCH 25/17 :5,364-5,375,2019
The role of salvage radiotherapy in recurrent thymoma
Radiation Oncology Journal 37/3 :193-200,2019

저서

Heinzerling JH, Cho J, Choy H. The role of Radiation Therapy in Metastatic Disease [Chapter. 53]. In: Cancer Metastasis: Biological Mechanisms and Therapeutics: Cambridge University Press; 2011. P 612-621.

보도자료

암 조기 발견땐 비수술적 시술로도 완치
http://www.segye.com/newsView/20150201001795?OutUrl=naver

다양한 조기암 치료법, 환자 삶의 질 높인다
https://www.edaily.co.kr/news/read?newsId=02410806609242640&mediaCodeNo=257

암 치료법 다양... 조기암일 경우 수술없이도 완치
http://www.ajunews.com/view/20150129152926479

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