이필휴

교수
    

  #파킨슨병#이상운동질환#치매#줄기세포#EBS명의

학력

1994년, 연세대학교 의과대학 학사
1999년, 연세대학교 의과대학 석사 (신경과학)
2004년, 연세대학교 의과대학 박사 (신경과학)

경력

1994년 3월 ~ 1995년 2월 세브란스병원 인턴
1995년 3월 ~ 1999년 2월 세브란스병원 전공의
2002년 5월 ~ 2004년 2월 아주대 병원 전임의
2004년 3월 ~ 2007년 아주대 병원 조교수
2007년 8월 ~ 2008년 3월 Department of Neuroscience, UCSD
2008년 4월 ~ 2009년 2월 세브란스 병원 신경과 조교수
2009년 3월 ~ 2014년 2월 세브란스 병원 신경과 부교수
2014년 3월 ~ 현재 세브란스 병원 신경과 교수

논문

Cortical metabolic changes in the cerebellar variant of multiple system atrophy: A voxel-based FDG-PET study in 41 patients. Neuroimage. 2007 Dec 15; [Epub ahead of print]

Lee PH, Lee G, Paik MJ. Polyunsaturated fatty acid levels in the cerebrospinal fluid of patients with Parkinson's disease and multiple system atrophy. Mov Disord. 2008 Jan 30;23(2):309-10

Yoon JH, Lee PH, Yoon SN. Subtraction brain SPECT imaging in a patient with paroxysmal exercise-induced dystonia: role of the primary somatosensory cortex. Arch Neurol. 2007 Nov;64(11):1652-6.

Shin DH, Han BS, Kim HS, Lee PH. Diffusion tensor imaging in patients with essential tremor.AJNR Am J Neuroradiol. 2008 Jan;29(1):151-3.

Lee PH, Kim JW, Bang OY, Ahn YH, Joo IS, Huh K.Autologous Mesenchymal Stem Cell Therapy Delays the Progression of Neurological Deficits in Patients With Multiple System Atrophy. Clin Pharmacol Ther. 2007 Sep 26; [Epub ahead of print]

Park HJ, Lee PH, Ahn YW, Choi YJ, Lee G, Lee DY, Chung ES, Jin BK. Neuroprotective effect of nicotine on dopaminergic neurons by anti-inflammatory action. Eur J Neurosci. 2007 Jul;26(1):79-89

Lee PH, Yeo SH, Yong SW, Kim YJ. Odour identification test and its relation to cardiac 123I-metaiodobenzylguanidine in patients with drug induced parkinsonism. J Neurol Neurosurg Psychiatry. 2007 Nov;78(11):1250-2.

Lee JS, Bang OY, Lee PH, Kim BM, Yong SW. Two cases of spontaneous middle cerebral arterial dissection causing ischemic stroke. J Neurol Sci. 2006 Dec 1;250(1-2):162-6.

Park HY, Lee PH, Shin DH, Kim GW. Anterograde amnesia with hippocampal lesions following glufosinate intoxication. Neurology. 2006 Sep 12;67(5):914-5.

Lee PH, Yeo SH, Kim HJ, Youm HY. Correlation between cardiac (123)I-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy. Mov Disord. 2006 Sep 7;21(11):1975-1977

Lee PH, Hwang EM, Hong HS, Boo JH, Mook-Jung I, Huh K. Effect of ischemic neuronal insults on amyloid precursor protein processing. Neurochem Res. 2006 Jun;31(6):821-7.

Lee PH, Kim JW, Bang OY, Joo IS, Yoon SN, Huh K. Cardiac 123I-MIBG scintigraphy in patients with essential tremor. Mov Disord. 2006 Aug;21(8):1235-8.

Lee PH, Lee G, Park HJ, Bang OY, Joo IS, Huh K. The plasma alpha-synuclein levels in patients with Parkinson's disease and multiple system atrophy. J Neural Transm. 2006 Oct;113(10):1435-9.

Lee PH, Oh SH, Bang OY, Joo IS, Huh K. Pathogenesis of deep white matter medullary infarcts: a diffusion weighted magnetic resonance imaging study. J Neurol Neurosurg Psychiatry. 2005 Dec;76(12):1659-63.

Lee PH, Shin DH, Kim JW, Song YS, Kim HS. Parkinsonism with basal ganglia lesions in a patient with uremia: Evidence of vasogenic edema. Parkinsonism Relat Disord. 2006 Mar;12(2):93-6.

Lee PH, Yeo SH. Isolated continuous rhythmic involuntary tongue movements following a pontine infarct. Parkinsonism Relat Disord. 2005 Dec;11(8):513-6.

Lee PH, Kim JS, Shin DH, Yoon SN, Huh K. Cardiac 123I-MIBG scintigraphy in patients with drug induced parkinsonism. J Neurol Neurosurg Psychiatry. 2006 Mar;77(3):372-4.

Lee PH, Yong SW, Ahn YH, Huh K. Correlation of midbrain diameter and gait disturbance in patients with idiopathic normal pressure hydrocephalus. J Neurol. 2005 Aug;252(8):958-63.

Lee PH, Lee JS, Shin DH, Kim BM, Huh K. Parkinsonism as an initial manifestation of dural arteriovenous fistula. Eur J Neurol. 2005 May;12(5):403-6.

Lee PH, Lee JH, Joo US. Thalamic infarct presenting with thalamic astasia. Eur J Neurol. 2005 Apr;12(4):317-9.

Lee PH, Lee JS, Yong SW, Huh K. Repetitive involuntary leg movements in patients with brainstem lesions involving the pontine tegmentum: evidence for a pontine inhibitory region in humans. Parkinsonism Relat Disord. 2005 Mar;11(2):105-10.

Lee PH, Bang OY, Hwang EM, Lee JS, Joo US, Mook-Jung I, Huh K. Circulating beta amyloid protein is elevated in patients with acute ischemic stroke. J Neural Transm. 2005 Oct;112(10):1371-9

Lee PH, Joo US, Yong SW, Huh K. Asymmetric freezing of gait in hemiparkinsonism-hemiatrophy. Neurology. 2004 Jul 27;63(2):E7.

Lee PH, Joo US, Bang OY, Seo CH. Basal ganglia hyperperfusion in a patient with systemic lupus erythematosus-related parkinsonism. Neurology. 2004 Jul 27;63(2):395-6.

Lee PH, Oh SH, Bang OY, Joo SY, Joo IS, Huh K. Infarct patterns in atherosclerotic middle cerebral artery versus internal carotid artery disease. Neurology. 2004 Apr 27;62(8):1291-6.

Lee PH, Oh SH, Bang OY, Joo IS, Huh K. Isolated middle cerebral artery disease: clinical and neuroradiological features depending on the pathogenesis. J Neurol Neurosurg Psychiatry. 2004 May;75(5):727-32.

Lee PH, Lee JS, Lee MH, Lee JD, Huh K. Subtraction brain SPECT imaging in a patient with gait ignition failure. Mov Disord. 2003 Dec;18(12):1542-5.

Lee PH, Bang OY, Oh SH, Joo IS, Huh K. Subcortical white matter infarcts: comparison of superficial perforating artery and internal border-zone infarcts using diffusion-weighted magnetic resonance imaging. Stroke. 2003 Nov;34(11):2630-5.

Lee JS, Bang OY, Lee PH, Kim BM, Yong SW. Two cases of spontaneous middle cerebral arterial dissection causing ischemic stroke. J Neurol Sci. 2006 Dec 1;250(1-2):162-6

Park HY, Lee PH, Shin DH, Kim GW. Anterograde amnesia with hippocampal lesions following glufosinate intoxication. Neurology. 2006 Sep 12;67(5):914-5.

Yong SW, Bang OY, Lee PH, Li WY. Internal and cortical border-zone infarction: clinical and diffusion-weighted imaging features. Stroke. 2006 Mar;37(3):841-6.

Bang OY, Lee PH, Heo KG, Joo US, Yoon SR, Kim SY. Specific DWI lesion patterns predict prognosis after acute ischaemic stroke within the MCA territory. J Neurol Neurosurg Psychiatry. 2005 Sep;76(9):1222-8.

Shin DH, Lee PH, Bang OY. Mechanisms of recurrence in subtypes of ischemic stroke: a hospital-based follow-up study. Arch Neurol. 2005 Aug;62(8):1232-7.

Bang OY, Kim JW, Lee JH, Lee MA, Lee PH, Joo IS, Huh K. Association of the metabolic syndrome with intracranial atherosclerotic stroke. Neurology. 2005 Jul 26;65(2):296-8.

Bang OY, Lee PH, Yoon SR, Lee MA, Joo IS, Huh K. Inflammatory markers, rather than conventional risk factors, are different between carotid and MCA atherosclerosis. J Neurol Neurosurg Psychiatry. 2005 Aug;76(8):1128-34.

Bang OY, Lee JS, Lee PH, Lee G. Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol. 2005 Jun;57(6):874-82.

Lee JS, Lee PH, Huh K. Periodic limb movements in sleep after a small deep subcortical infarct. Mov Disord. 2005 Feb;20(2):260-1.

Bang OY, Lee PH, Kim SY, Kim HJ, Huh K. Pontine atrophy precedes cerebellar degeneration in spinocerebellar ataxia 7: MRI-based volumetric analysis. J Neurol Neurosurg Psychiatry. 2004 Oct;75(10):1452-6.

Bang OY, Joo SY, Lee PH, Joo US, Lee JH, Joo IS, Huh K. The course of patients with lacunar infarcts and a parent arterial lesion: similarities to large artery vs small artery disease. Arch Neurol. 2004 Apr;61(4):514-9.

Bang OY, Heo KG, Kwak Y, Lee PH, Joo IS, Huh K. Global aphasia without hemiparesis: lesion analysis and its mechanism in 11 Korean patients. J Neurol Sci. 2004 Jan 15;217(1):101-6.

Bang OY, Huh K, Lee PH, Kim HJ. Clinical and neuroradiological features of patients with spinocerebellar ataxias from Korean kindreds. Arch Neurol. 2003 Nov;60(11):1566-74.

Bang OY, Lee PH, Joo SY, Lee JS, Joo IS, Huh K. Frequency and mechanisms of stroke recurrence after cryptogenic stroke. Ann Neurol. 2003 Aug;54(2)

MRI features of infarcts with potential cardiac source of embolism in the Yonsei Stroke Registry (YSR), Korea
YONSEI MEDICAL JOURNAL 41/4 :431-435,2000

Global aphasia without hemiparesis: lesion analysis and its mechanism in 11 Korean patients
JOURNAL OF THE NEUROLOGICAL SCIENCES 217/ :101-106,2004

Isolated middle cerebral artery disease: clinical and neuroradiological features depending on the pathogenesis
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 75/ :727-732,2004

The course of patients with lacunar infarcts and a parent arterial lesion - Similarities to large artery vs small artery disease
ARCHIVES OF NEUROLOGY 61/ :514-519,2004

Infarct patterns in atherosclerotic middle cerebral artery versus internal carotid artery disease
NEUROLOGY 62/ :1291-1296,2004

Asymmetric freezing of gait in hemiparkinsonism-hemiatrophy
NEUROLOGY 63/ :E7-E7,2004

Pontine atrophy precedes cerebellar degeneration in spinocerebellar ataxia 7: MRI-based volumetric analysis
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 75/ :1452-1456,2004

Basal ganglia hyperperfusion in a patient with systemic lupus erythematosus-related parkinsonism
NEUROLOGY 63/ :395-396,2004

Circulating beta amyloid protein is elevated in patients with acute ischemic stroke
JOURNAL OF NEURAL TRANSMISSION 112/ :1371-1379,2005

Repetitive involuntary leg movements in patients with brainstem lesions involving the pontine tegmentum: evidence for a pontine inhibitory region in humans
PARKINSONISM & RELATED DISORDERS 11/ :105-110,2005

Thalamic infarct presenting with thalamic astasia
EUROPEAN JOURNAL OF NEUROLOGY 12/ :317-319,2005

Parkinsonism as an initial manifestation of dural arteriovenous fistula
EUROPEAN JOURNAL OF NEUROLOGY 12/ :403-406,2005

Correlation of midbrain diameter and gait disturbance in patients with idiopathic normal pressure hydrocephalus
JOURNAL OF NEUROLOGY 252/ :958-963,2005

Autologous mesenchymal stem cell transplantation in stroke patients
ANNALS OF NEUROLOGY 57/ :874-882,2005

Association of the metabolic syndrome with intracranial atherosclerotic stroke
NEUROLOGY 65/ :296-298,2005

Inflammatory markers, rather than conventional risk factors, are different between carotid and MCA atherosclerosis
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 76/ :1128-1134,2005

Mechanisms of recurrence in subtypes of ischemic stroke - A hospital-based follow-up study
ARCHIVES OF NEUROLOGY 62/ :1232-1237,2005

Specific DWI lesion patterns predict prognosis after acute ischaemic stroke within the MCA territory
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 76/ :1222-1228,2005

Pathogenesis of deep white matter medullary infarcts: a diffusion weighted magnetic resonance imaging study
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 76/ :1659-1663,2005

Parkinsonism with basal ganglia lesions in a patient with uremia: Evidence of vasogenic edema
PARKINSONISM & RELATED DISORDERS 12/ :93-96,2006

Cardiac I-123-MIBG scintigraphy in patients with drug induced Parkinsonism
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 77/ :372-374,2006

Internal and cortical border-zone infarction - Clinical and diffusion-weighted imaging features
STROKE 37/ :841-846,2006

Cardiac I-123-MIBG scintigraphy in patients with essential tremor
MOVEMENT DISORDERS 21/ :1235-1238,2006

The plasma alpha-synuclein levels in patients with Parkinson's disease and multiple system atrophy
JOURNAL OF NEURAL TRANSMISSION 113/ :1435-1439,2006

Effect of ischemic neuronal insults on amyloid precursor protein processing
NEUROCHEMICAL RESEARCH 31/ :821-827,2006

Correlation between cardiac I-123-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy
MOVEMENT DISORDERS 21/11 :1975-1977,2006

Unilateral mydriasis from ipratropium in transplant patients
NEUROLOGY 67/5 :914-914,2006

Two cases of spontaneous middle cerebral arterial dissection causing ischemic stroke
JOURNAL OF THE NEUROLOGICAL SCIENCES 250/ :162-166,2006

Odour identification test and its relation to cardiac I-123-metaiodobenzylguanidine in patients with drug induced parkinsonism
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 78/ :1250-1252,2007

A comparison of cerebral glucose metabolism in Parkinson's disease, Parkinson's disease dementia and dementia with Lewy bodies
EUROPEAN JOURNAL OF NEUROLOGY 14/ :1357-1362,2007

Neuroprotective effect of nicotine on dopaminergic neurons by anti-inflammatory action
EUROPEAN JOURNAL OF NEUROSCIENCE 26/ :79-89,2007

Subtraction brain SPECT imaging in a patient with paroxysmal exercise-induced dystonia - Role of the primary somatosensory cortex
ARCHIVES OF NEUROLOGY 64/ :1652-1656,2007

Analysis of PARK genes in a Korean cohort of early-onset Parkinson disease
Neurogenetics 9/4 :263-269,2008

Cortical metabolic changes in the cerebellar variant of multiple system atrophy: A voxel-based FDG-PET study in 41 patients
Neuroimage 40/ :796-801,2008

Movement disorders at a university hospital emergency room - An analysis of clinical pattern and etiology
Journal Of Neurology 255/5 :745-749,2008

Autologous mesenchymal stem cell therapy delays the progression of neurological deficits in patients with multiple system atrophy
Clinical Pharmacology & Therapeutics 83/ :723-730,2008

Diffusion tensor Imaging in patients with essential tremor
American Journal Of Neuroradiology 29/ :151-153,2008

Changes in Cerebral Glucose Metabolism in Patients with Parkinson Disease with Dementia After Cholinesterase Inhibitor Therapy
Journal Of Nuclear Medicine 49/12 :2006-2011,2008

Mesenchymal stem cells therapy exerts neuroprotection in a progressive animal model of Parkinson's disease
Journal Of Neurochemistry 107/ :141-151,2008

Mesenchymal Stem Cells for Ischemic Stroke: Changes in Effects After Ex Vivo Culturing
Cell Transplantation 17/ :1045-1059,2008

Neuroprotective Effects of Human Mesenchymal Stem Cells on Dopaminergic Neurons Through Anti-Inflammatory Action
Glia 57/1 :13-23,2009

The free fatty acid metabolome in cerebral ischemia following human mesenchymal stem cell transplantation in rats
Clinica Chimica Acta 402/ :25-30,2009

Serum Cholesterol Levels and the Risk of Multiple System Atrophy: A Case-Control Study
Movement Disorders 24/5 :752-758,2009

Non-conventional risk factors were associated with infarct patterns in ischemic stroke
Clinical Neurology And Neurosurgery 111/2 :134-139,2009

Bone Marrow-Derived Mesenchymal Stem Cell Therapy as a Candidate Disease-Modifying Strategy in Parkinson's Disease and Multiple System Atrophy
Journal Of Clinical Neurology 5/ :1-10,2009

White matter hyperintensities in patients with multiple system atrophy
Journal Of Neurology 256/10 :1663-1670,2009

A Novel PANK2 Mutation in a Patient with Atypical Pantothenate-Kinase-Associated Neurodegeneration Presenting with Adult-Onset Parkinsonism
Journal Of Clinical Neurology 5/ :192-194,2009

Associated conditions and clinical significance of awake bruxism
Geriatrics & Gerontology International 9/ :382-390,2009

Neuroprotective effect of l-dopa on dopaminergic neurons is comparable to pramipexol in MPTP-treated animal model of Parkinson's disease: a direct comparison study
Journal Of Neurochemistry 111/4 :1042-1050,2009

Mitochondrial Inhibitor 3-Nitroproprionic Acid Enhances Oxidative Modification of Alpha-synuclein in a Transgenic Mouse Model of Multiple System Atrophy
Journal Of Neuroscience Research 87/12 :2728-2739,2009

A Comparison of Gray and White Matter Density in Patients with Parkinson's Disease Dementia and Dementia with Lewy Bodies Using, Voxel-Based Morphometry
Movement Disorders 25/ :28-34,2010

Formation of parkin aggregates and enhanced PINK1 accumulation during the pathogenesis of Parkinson's disease
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 393/4 :824-828,2010

A comparative analysis of cognitive profiles and white-matter alterations using voxel-based diffusion tensor imaging between patients with Parkinson's disease dementia and dementia with Lewy bodies
Journal Of Neurology Neurosurgery And Psychiatry 81/3 :320-326,2010

Chorea induced by antihistamine drugs
Movement Disorders 25/4 :519-520,2010

The effect of levodopa treatment on cerebral hemodynamics in patients with Parkinson's disease: Serial transcranial Doppler studies
Parkinsonism & Related Disorders 16/3 :225-227,2010

The missing button sign as a tool for detecting proximal internal carotid artery occlusion
Journal Of Clinical Neuroscience 17/ :1506-1509,2010

Neuroanatomic basis of amnestic MCI differs in patients with and without Parkinson disease
Neurology 75/ :2009-2016,2010

A Comparison of LEDD and Motor Scores Following STN-DBS Treatment in Patient with Young Onset vs. Late Onset Parkinson's Disease
Neuromodulation 13/ :255-260,2010

A Case-Control Study of Multiple System Atrophy in Korean Patients
Movement Disorders 25/12 :1953-1959,2010

A Long-Term Follow-Up Study of Intravenous Autologous Mesenchymal Stem Cell Transplantation in Patients With Ischemic Stroke
Stem Cells 28/6 :1099-1106,2010

Enhancing trophic support of mesenchymal stem cells by ex vivo treatment with trophic factors
Journal of the Neurological Sciences 298/1-2 :28-34,2010

The pattern of cortical atrophy in patients with Parkinson's disease according to cognitive status
MOVEMENT DISORDERS 26/2 :289-296,2011

Placebo effects on analgesia related to testosterone and premotor activation
NEUROREPORT 22/9 :419-423,2011

Comparison of Endothelial Progenitor Cells in Parkinson's Disease Patients Treated with Levodopa and Levodopa/COMT Inhibitor
PLOS ONE 6/6 :e21536-,2011

Uric Acid as a Potential Disease Modifier in Patients with Multiple System Atrophy
MOVEMENT DISORDERS 26/8 :1533-1536,2011

Neuroprotective Effect of Human Mesenchymal Stem Cells in an Animal Model of Double Toxin-Induced Multiple System Atrophy Parkinsonism
CELL TRANSPLANTATION 20/6 :827-835,2011

Blood-brain barrier impairment is functionally correlated with clinical severity in patients of multiple system atrophy
NEUROBIOLOGY OF AGING 32/12 :2183-2189,2011

Mid-life and late-life vascular risk factors and dementia in Korean men and women
ARCHIVES OF GERONTOLOGY AND GERIATRICS 52/3 :117-122,2011

Parkinsonism Associated with Glucocerebrosidase Mutation
JOURNAL OF CLINICAL NEUROLOGY 7/2 :99-101,2011

Subcortical white matter hyperintensities within the cholinergic pathways of Parkinson's disease patients according to cognitive status
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 83/ :315-321,2012

the pattern of cortical atrophy in parkinson's diesase with mild cognitive impairment according to the timing of cognitive dysfunction
JOURNAL OF NEUROLOGY 259/3 :469-473,2012

Association of mutations in the glucocerebrosidase gene with Parkinson disease in a Korean population.
NEUROSCIENCE LETTERS 514/1 :12-15,2012

Volumetric analysis of the substantia innominata in patients with Parkinson’s disease according to cognitive status.
NEUROBIOLOGY OF AGING 33/7 :1265-1272,2012

Neurocognitive and atrophic patterns in Parkinson's disease based on subjective memory complaints.
JOURNAL OF NEUROLOGY 259/8 :1706-1712,2012

A randomized trial of mesenchymal stem cells in multiple system atrophy.
ANNALS OF NEUROLOGY 72/1 :32-40,2012

Neuroanatomical substrates of visual hallucinations in patients with non-demented Parkinson's disease
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 83/ :1155-1161,2012

Neurogenesis in the subventricular zone and enhance differentiation of neural precursor cells into dopaminergic neurons in the substantia nigra of a Parkinsonian model
CELL TRANSPLANTATION 21/8 :1629-1640,2012

Elevated Homocysteine by Levodopa Is Detrimental to Neurogenesis in Parkinsonian Model.
PLOS ONE 7 /11 :e50496-e50496,2012

Assessment of the Effects of Unilateral Electrode Dysfunction in Patients With Parkinson Disease Undergoing Bilateral Subthalamic Nucleus Deep Brain Stimulation
NEUROSURGERY 70/1 Supp :ons163-ons169,2012

Mesenchymal Stem Cells Augment Neurogenesis in the Subventricular Zone and Enhance Differentiation of Neural Precursor Cells Into Dopaminergic Neurons in the Substantia Nigra of a Parkinsonian Model
CELL TRANSPLANTATION 21/8 :1629-1640,2012

alpha-Synuclein pathology is related to postoperative delirium in patients undergoing gastrectomy
NEUROLOGY 80/ :810-813,2013

changes in the blood-brain barrier status closely correlate with the rate of disease proression in patients with mltiple system atrophy: a longitudinal study
PARKINSONISM & RELATED DISORDERS 19/4 :450-452,2013

Levodopa-lnduced dyskinesia in a Patient who has normal Presynaptic dopaminergic neurons
MOVEMENT DISORDERS 28/8 :1152-1153,2013

Identification of ATM Mutations in Korean Siblings with Ataxia-Telangiectasia
ANNALS OF LABORATORY MEDICINE 33/3 :217-220,2013

Effect of APOE genotype on gray matter density in patients with Parkinson's disease
PARKINSONISM & RELATED DISORDERS 19/1 :138-140,2013

Neuroanatomical heterogeneity of essential tremor according to propranolol response
PLOS ONE 8/12 :e84054-,2013

Thalamic volume and related visual recognition are associated with freezing of gait in non-demented patients with Parkinson's disease.
PARKINSONISM & RELATED DISORDERS 19/12 :1106-1109,2013

The perfusion pattern in a patient with lithium intoxication mimicking creutzfeldt-jakob disease
JOURNAL OF CLINICAL PSYCHIATRY 74/12 :e1134-e1135,2013

Dental implant-induced task-specific oromandibular dystonia
EUROPEAN JOURNAL OF NEUROLOGY 20/6 :e80-,2013

Predictive value of the smell identification test for nigrostriatal dopaminergic depletion in Korean tremor patients
PARKINSONISM & RELATED DISORDERS 19/11 :1018-1021,2013

Levodopa-induced dyskinesia in a patient who has normal presynaptic dopaminergic neurons
MOVEMENT DISORDERS 28/ :1152-1153,2013

정신분열병의 임상증세를 보였던 항NMDA수용체뇌염
대한신경과학회지 31/2 :115-117,2013

Mesenchymal stem cells enhance autophagy and increase β-amyloid clearance in Alzheimer disease models
AUTOPHAGY 10/1 :32-44,2014

Presynaptic dopamine depletion predicts levodopa-induced dyskinesia in de novo Parkinson disease
NEUROLOGY 82/18 :1597-1604,2014

The Mild Cognitive Impairment Stage of Dementia With Lewy Bodies and Parkinson Disease A Comparison of Cognitive Profiles
ALZHEIMER DISEASE & ASSOCIATED DISORDERS 28/2 :151-155,2014

The burden of white matter hyperintensities is a predictor of progressive mild cognitive impairment in patients with Parkinson's disease.
EUROPEAN JOURNAL OF NEUROLOGY 21/6 :922-928,2014

Clinical and Genetic Aspects in Twelve Korean Patients with Adrenomyeloneuropathy
YONSEI MEDICAL JOURNAL 55/3 :676-682,2014

Mesenchymal stem cells can modulate longitudinal changes in cortical thickness and its related cognitive decline in patients with multiple system atrophy
FRONTIERS IN AGING NEUROSCIENCE 6/JUN :0-0,2014

Subjective cognitive decline predicts future deterioration in cognitively normal patients with Parkinson's disease.
NEUROBIOLOGY OF AGING 35/7 :1739-1743,2014

Neuroprotective effects of mesenchymal stem cells through autophagy modulation in a parkinsonian model
NEUROBIOLOGY OF AGING 35/8 :1920-1928,2014

Cerebral microbleeds in patients with Parkinson's disease.
JOURNAL OF NEUROLOGY 261/8 :1628-1635,2014

Cognitive and cortical thinning patterns of subjective cognitive decline in patients with and without Parkinson's disease..pdf
PARKINSONISM & RELATED DISORDERS 20/9 :999-1003,2014

Dopaminergic Modulation of Resting-State Functional Connectivity in De Novo Patients With Parkinson's Disease
HUMAN BRAIN MAPPING 35/11 :5431-5441,2014

Endothelial Dysfunction and Hyperhomocysteinemia in Parkinson's Disease: Flow-Mediated Dilation Study
MOVEMENT DISORDERS 29/12 :1551-1555,2014

Exploratory analysis of neuropsychological and neuroanatomical correlates of progressive mild cognitive impairment in Parkinson's disease
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 85/1 :7-16,2014

Olfactory performance acts as a cognitive. reserve in non-demented patients with Parkinson's disease
PARKINSONISM & RELATED DISORDERS 20/2 :186-191,2014

Depression and voice handicap in Parkinson disease
JOURNAL OF THE NEUROLOGICAL SCIENCES 346/1-2 :112-115,2014

Neural correlates of progressive reduction of bradykinesia in de novo Parkinson's disease
PARKINSONISM & RELATED DISORDERS 20/12 :1376-1381,2014

Subcortical vascular dementia (SVaD) without hypertension (HTN) may be a unique subtype of vascular dementia (VaD)
ARCHIVES OF GERONTOLOGY AND GERIATRICS 58/2 :231-235,2014

Current Status of Huntington's Disease in Korea: A Nationwide Survey and National Registry Analysis
Journal of Movement Disorders 8/1 :14-20,2015

Topography of cortical thinning associated with white matter hyperintensities in Parkinson's disease
PARKINSONISM & RELATED DISORDERS 21/4 :372-377,2015

Olfactory performance and resting state functional connectivity in non-demented drug native patients with Parkinson's disease
HUMAN BRAIN MAPPING 36/5 :1716-1727,2015

Mesenchymal Stem Cells Increase Hippocampal Neurogenesis and Neuronal Differentiation by Enhancing the Wnt Signaling Pathway in an Alzheimer's Disease Model
CELL TRANSPLANTATION 24/6 :1097-1109,2015

Patterns of Neuropsychological Profile and Cortical Thinning in Parkinson's Disease with Punding
PLOS ONE 10/7 :e0134468-,2015

Cerebral microbleeds in patients with dementia with lewy bodies and Parkinson disease dementia
AMERICAN JOURNAL OF NEURORADIOLOGY 36/9 :1642-1647,2015

Mesenchymal stem cells stabilize the blood-brain barrier through regulation of astrocytes
STEM CELL RESEARCH & THERAPY 187/6 :1-12,2015

Comparison of regional brain atrophy and cognitive impairment between pure akinesia with gait freezing and Richardson’s syndrome
FRONTIERS IN AGING NEUROSCIENCE 180/7 :1-7,2015

Is normosmic Parkinson disease a unique clinical phenotype?
NEUROLOGY 85/15 :1270-1275,2015

Apathy and olfactory dysfunction in early Parkinson's disease
Journal of Movement Disorders 8/1 :21-25,2015

Gender Differences in Age-Related Striatal Dopamine Depletion in Parkinson's Disease
Journal of Movement Disorders 8/3 :130-135,2015

Nigrostriatal dopamine-independent resting-state functional networks in Parkinson's disease
NEUROIMAGE 119/- :296-304,2015

Effects of Mesenchymal Stem Cell Treatment on the Expression of Matrix Metalloproteinases and Angiogenesis during Ischemic Stroke Recovery
PLOS ONE 10/12 :e0144218-,2015

Is dominant-side onset associated with a better motor compensation in Parkinson's disease?
MOVEMENT DISORDERS 30/14 :1921-1925,2015

Association of body mass index and the depletion of nigrostriatal dopamine in Parkinson’s disease
NEUROBIOLOGY OF AGING 38/- :197-204,2016

Apathy and striatal dopamine defects in non-demented patients with Parkinson's disease
PARKINSONISM & RELATED DISORDERS 23/- :62-65,2016

Mesenchymal Stem Cells Inhibit Transmission of α-Synuclein by Modulating Clathrin-Mediated Endocytosis in a Parkinsonian Model
CELL REPORTS 14/4 :835-849,2016

Does education modify motor compensation in Parkinson's disease?
JOURNAL OF THE NEUROLOGICAL SCIENCES 362/- :118-120,2016

Prevalence and treatment pattern of Parkinson's disease dementia in Korea
GERIATRICS & GERONTOLOGY INTERNATIONAL 16/2 :230-236,2016

Clinical Heterogeneity of Atypical Pantothenate Kinase-Associated Neurodegeneration in Koreans
Journal of Movement Disorders 9/1 :20-27,2016

Effect of olfactory impairment and white matter hyperintensities on cognition in Parkinson's disease
PARKINSONISM & RELATED DISORDERS 24/ :95-99,2016

Different Functional and Microstructural Changes Depending on Duration of Mild Cognitive Impairment in Parkinson Disease
AMERICAN JOURNAL OF NEURORADIOLOGY 37/5 :897-903,2016

Persistent Drug-Induced Parkinsonism in Patients with Normal Dopamine Transporter Imaging
PLOS ONE 11/6 :e0157410-,2016

Does serum uric acid act as a modulator of cerebrospinal fluid Alzheimer's disease biomarker related cognitive decline?
EUROPEAN JOURNAL OF NEUROLOGY 23/5 :948-957,2016

Striatal Dopamine Depletion Patterns and Early Non-Motor Burden in Parkinsons Disease.
PLOS ONE 11/8 :e0161316-,2016

Assessment of blood-brain barrier permeability by dynamic contrast-enhanced MRI in transient middle cerebral artery occlusion model after locali007Aed brain cooling in rats
KOREAN JOURNAL OF RADIOLOGY 17/5 :715-724,2016

Optic nerve integrity as a visuospatial cognitive predictor in Parkinson’s disease
PARKINSONISM & RELATED DISORDERS Parkinson :41-45,2016

Posterior Ventricular Enlargement to Differentiate Dementia with Lewy Bodies from Alzheimer’s Disease
JOURNAL OF ALZHEIMERS DISEASE Journal o :1,237-1,243,2016

The MMSE and MoCA for Screening Cognitive Impairment in Less Educated Patients with Parkinson’s Disease
Journal of Movement Disorders 9/3 :152-159,2016

Mesenchymal stem cells enhance α-synuclein clearance via M2 microglia polarization in experimental and human parkinsonian disorder
ACTA NEUROPATHOLOGICA 132/5 :685-701,2016

A prognostic factor in focal hand dystonia: typist's cramp cases and literature review
JOURNAL OF THE NEUROLOGICAL SCIENCES 371/12 :85-87,2016

Volumetric analysis of the cerebellum in patients with progressive supranuclear palsy
EUROPEAN JOURNAL OF NEUROLOGY 24/1 :212-218,2017

Cognitive and Neuroanatomical Correlates in Early Versus Late Onset Parkinson's Disease Dementia.
JOURNAL OF ALZHEIMERS DISEASE 55/2 :485-495,2017

Premorbid exercise engagement and motor reserve in Parkinson's disease
PARKINSONISM & RELATED DISORDERS 34/1 :49-53,2017

Lack of association between LRRK2 G2385R and cognitive dysfunction in Korean patients with Parkinson's disease
JOURNAL OF CLINICAL NEUROSCIENCE 36/ :108-113,2017

The Cleavage Effect of Mesenchymal Stem Cell and Its Derived Matrix Metalloproteinase-2 on Extracellular α-Synuclein Aggregates in Parkinsonian Models
STEM CELLS TRANSLATIONAL MEDICINE 6/3 :949-961,2017

Feasibility and Efficacy of Intra-Arterial Administration of Mesenchymal Stem Cells in an Animal Model of Double Toxin-Induced Multiple System Atrophy.
STEM CELLS TRANSLATIONAL MEDICINE 6/5 :1,424-1,433,2017

Mesenchymal Stem Cells Stabilize Axonal Transports for Autophagic Clearance of α-Synuclein in Parkinsonian Models
STEM CELLS 35/8 :1,934-1,947,2017

Sleep Disturbance May Alter White Matter and Resting State Functional Connectivities in Parkinson's Disease
SLEEP 40/3 :1-10,2017

Rapid eye movement sleep behavior disorder and striatal dopamine depletion in patients with Parkinson’s disease
EUROPEAN JOURNAL OF NEUROLOGY 24/10 :1,314-1,319,2017

Familiar hyperekplexia, a potential cause of cautious gait: A new Korean case and a systematic review of phenotypes
Journal of Movement Disorders 10/1 :53-58,2017

Dementia-Predicting Cognitive Risk Score and Its Correlation with Cortical Thickness in Parkinson Disease
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 44/3-4 :203-212,2017

Subcortical shape analysis of progressive mild cognitive impairment in Parkinson's disease.
MOVEMENT DISORDERS 32/10 :1,447-1,456,2017

Does smoking impact dopamine neuronal loss in de novo Parkinson's disease?
ANNALS OF NEUROLOGY 82/5 :850-854,2017

Microstructural white matter alterations in patients with drug induced parkinsonism
HUMAN BRAIN MAPPING 38/12 :6,043-6,052,2017

Effects of dopaminergic depletion and brain atrophy on neuropsychiatric symptoms in de novo Parkinson’s disease.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 89/2 :197-204,2018

Early-onset drug-induced parkinsonism after exposure to offenders implies nigrostriatal dopaminergic dysfunction
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 89/2 :169-174,2018

Presynaptic dopamine depletion determines the timing of levodopa-induced dyskinesia onset in Parkinson’s disease
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 45/3 :423-431,2018

Subjective Cognitive Complaints and Objective Cognitive Impairment in Parkinson's Disease
JOURNAL OF CLINICAL NEUROLOGY 14/1 :16-21,2018

The cholinergic contribution to the resting-state functional network in non-demented Parkinson's disease
SCIENTIFIC REPORTS 8/1 :7,683-7,692,2018

Effect of striatal dopamine depletion on cognition in de novo Parkinson's disease
PARKINSONISM & RELATED DISORDERS 51/ :43-48,2018

Gender-specific effect of uric acid on resting-state functional networks in de novo Parkinson's disease
PARKINSONISM & RELATED DISORDERS 52/ :49-54,2018

Putaminal dopamine depletion in de novo Parkinson’s disease predicts future development of wearing-off
PARKINSONISM & RELATED DISORDERS 53/ :96-100,2018

Validation of the Korean Version of the Scales for Outcomes in Parkinson's Disease-Sleep
JOURNAL OF KOREAN MEDICAL SCIENCE 33/2 :-,2018

The presence of depression in de novo Parkinson's disease reflects poor motor compensation
PLOS ONE 13/9 :1-10,2018

Olfactory dysfunction in Alzheimer's disease- and Lewy body-related cognitive impairment
ALZHEIMERS & DEMENTIA 14/10 :1,243-1,252,2018

The Pattern of Striatal Dopamine Depletion as a Prognostic Marker in De Novo Parkinson Disease
CLINICAL NUCLEAR MEDICINE 43/11 :787-792,2018

Does Late Levodopa Administration Delay the Development of Dyskinesia in Patients with De Novo Parkinson's Disease?
CNS DRUGS 32/10 :971-979,2018

A Novel Heterozygous ANO3 Mutation with Basal Ganglia Dysfunction in a Patient with Adult-Onset Isolated Segmental Dystonia
JOURNAL OF CLINICAL NEUROLOGY 14/4 :596-597,2018

Amyloid-β-related and unrelated cortical thinning in dementia with Lewy bodies.
NEUROBIOLOGY OF AGING 72/ :32-39,2018

Parkinson's disease-related non-motor features as risk factors for post-operative delirium in spinal surgery.
PLOS ONE 13/4 :e0195749-e0195760,2018

The role of 18F-FP-CIT PET in differentiation of progressive supranuclear palsy and frontotemporal dementia in the early stage
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 45/9 :1,585-1,595,2018

Gastrectomy and nigrostriatal dopaminergic depletion in de novo Parkinson's disease
MOVEMENT DISORDERS 34/2 :299-301,2019

Levodopa-induced dyskinesia is closely linked to progression of frontal dysfunction in PD
NEUROLOGY 92/13 :e1468-,2019

Dysautonomia is associated with structural and functional alterations in Parkinson disease
NEUROLOGY 92/13 :e1456-,2019

Does the Side Onset of Parkinson's Disease Influence the Time to Develop Levodopa-Induced Dyskinesia?
JOURNAL OF PARKINSONS DISEASE 9/1 :241-247,2019

Mild cognitive impairment reverters have a favorable cognitive prognosis and cortical integrity in Parkinson's disease
NEUROBIOLOGY OF AGING 78/ :168-177,2019

Distinct FP-CIT PET patterns of Alzheimer’s disease with parkinsonism and dementia with Lewy bodies
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 46/8 :1,652-1,660,2019

Olfactory anosognosia is a predictor of cognitive decline and dementia conversion in Parkinson's disease.
JOURNAL OF NEUROLOGY 266/7 :1,601-1,610,2019

Beneficial effect of estrogen on nigrostriatal dopaminergic neurons in drug-naive postmenopausal Parkinson's disease.
SCIENTIFIC REPORTS 9/1 :e10531-,2019

Clinical relevance of amnestic versus non-amnestic mild cognitive impairment subtyping in Parkinson's disease
EUROPEAN JOURNAL OF NEUROLOGY 26/5 :766-773,2019

Effects of Lewy body disease and Alzheimer disease on brain atrophy and cognitive dysfunction
NEUROLOGY 92/17 :e2015-e2026,2019

Low-dose pioglitazone can ameliorate learning and memory impairment in a mouse model of dementia by increasing LRP1 expression in the hippocampus.
SCIENTIFIC REPORTS 9/ :e4414-,2019

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