이승태
#유전체검사#희귀질환유전검사#혈액암유전검사
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학력
ㆍ 연세대학교 의과대학 의학사(1999)
ㆍ 성균관대학교 의과대학 석사 (2007)
ㆍ 성균관대학교 의과대학 박사 (2009)
ㆍ 성균관대학교 의과대학 석사 (2007)
ㆍ 성균관대학교 의과대학 박사 (2009)
경력
ㆍ 1999-2002 공중보건의
ㆍ 2002-2003 서울아산병원 인턴
ㆍ 2004-2008 삼성서울병원 전공의
ㆍ 2008-2015 삼성서울병원 임상강사, 임상조교수, 임상전임강사, 진료부교수
ㆍ 2011-2012 University of California, San Francisco 방문교수
ㆍ 2015-현재 연세대학교 의과대학 세브란스병원 임상부교수, 부교수
ㆍ 2002-2003 서울아산병원 인턴
ㆍ 2004-2008 삼성서울병원 전공의
ㆍ 2008-2015 삼성서울병원 임상강사, 임상조교수, 임상전임강사, 진료부교수
ㆍ 2011-2012 University of California, San Francisco 방문교수
ㆍ 2015-현재 연세대학교 의과대학 세브란스병원 임상부교수, 부교수
논문
Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures
NUCLEIC ACIDS RESEARCH 43/5 :2590-2602,2015
NOTCH2 missplicing can occur in relation to apoptosis
BLOOD 126/14 :1731-1732,2015
Whole-genome fingerprint of the DNA methylome during human B cell differentiation
NATURE GENETICS 47/7 :746-746,2015
A subset of CD45+/CD19-cells in bone marrow may be associated with clinical outcomes of patients with mantle cell lymphoma
LEUKEMIA & LYMPHOMA 56/11 :3052-3057,2015
Genome-wide CpG island methylation and intergenic demethylation propensities vary among different tumor sites
NUCLEIC ACIDS RESEARCH 44/3 :1105-1117,2016
유전체 의학 시대를 맞이한 유전성 유방암-난소암 증후군 유전 검사의 임상적 함의: 임상의사가 바라본 전망
Journal of Breast Disease 4/1 :1-9,2016
Frequency and Clinical Characteristics of Intrachromosomal Amplification of Chromosome 21 in Korean Childhood B-lineage Acute Lymphoblastic Leukemia
ANNALS OF LABORATORY MEDICINE 36/5 :475-480,2016
Evaluation of an amplicon-based next-generation sequencing panel for detection of BRCA1 and BRCA2 genetic variants
BREAST CANCER RESEARCH AND TREATMENT 158/3 :433-440,2016
Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of DNMT3A mutations
ONCOTARGET 7/34 :54,825-54,837,2016
t(12;17)(p13;q12)/TAF15-ZNF384 Rearrangement in Acute Lymphoblastic Leukemia
ANNALS OF LABORATORY MEDICINE 36/4 :396-398,2016
Detection of MYD88 L265P in patients with lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia and other B-cell non-Hodgkin lymphomas
Blood Research 51/3 :181-186,2016
Usefulness of Flow Cytometric Analysis for Detecting Leptomeningeal Diseases in Non-Hodgkin Lymphoma
ANNALS OF LABORATORY MEDICINE 36/3 :209-214,2016
Chronic Myeloid Leukemia With Rare Variant b2a3 (e13a3) BCR-ABL1 Fusion
ANNALS OF LABORATORY MEDICINE 36/3 :287-289,2016
BRCA1 and BRCA2 mutation predictions using the BRCAPRO and Myriad models in Korean ovarian cancer patients
GYNECOLOGIC ONCOLOGY 145/1 :137-141,2017
Comparison of Clinical Outcomes of BRCA1/2 Pathologic Mutation, Variants of Unknown Significance, or Wild Type Epithelial Ovarian Cancer Patients
CANCER RESEARCH AND TREATMENT 49/2 :408-415,2017
Validation and Optimization of the Ion Torrent S5 XL Sequencer and Oncomine Workflow for BRCA1 and BRCA2 Genetic Testing
ONCOTARGET 8/21 :34,858-34,866,2017
Telomere length in alcohol dependence: A role for impulsive choice and childhood maltreatment
PSYCHONEUROENDOCRINOLOGY 83/ :72-78,2017
The effect of trauma and PTSD on telomere length: An exploratory study in people exposed to combat trauma
SCIENTIFIC REPORTS 7/1 :4375-,2017
Quinidine Trial in a Patient with Epilepsy of Infancy with Migrating Focal Seizure and KCNT1 Mutation
Journal of the Korean Child Neurology Society(대한소아신경학회지) 25/3 :169-173,2017
Identification of a Novel BRCA1 Pathogenic Mutation in Korean Patients Following Reclassification of BRCA1 and BRCA2 Variants According to the ACMG Standards and Guidelines Using Relevant Ethnic Controls
CANCER RESEARCH AND TREATMENT 49/4 :1,012-1,021,2017
Diagnostic application of clinical exome sequencing in Leber congenital amaurosis
MOLECULAR VISION 23/ :649-659,2017
Accuracy of Next-Generation Sequencing for Molecular Diagnosis in Patients With Infantile Nystagmus Syndrome
JAMA OPHTHALMOLOGY 135/12 :1376-1385,2017
Mowat-Wilson syndrome presenting with fever-associated seizures.
EPILEPTIC DISORDERS 19/4 :481-485,2017
Detection of Immunoglobulin Heavy Chain Gene Clonality by Next-Generation Sequencing for Minimal Residual Disease Monitoring in B-Lymphoblastic Leukemia
ANNALS OF LABORATORY MEDICINE 37/4 :331-335,2017
Efficacy of Stiripentol in Dravet Syndrome with or without SCN1A Mutations
JOURNAL OF CLINICAL NEUROLOGY 14/1 :22-28,2018
Application of Multiplex Ligation-Dependent Probe Amplification Assay for Genotyping Major Blood Group Systems Including DEL Variants in the D-Negative Korean Population
ANNALS OF LABORATORY MEDICINE 38/1 :32-38,2018
Variants of cancer susceptibility genes in Korean BRCA1/2 mutation-negative patients with high risk for hereditary breast cancer
BMC CANCER 18/1 :83-90,2018
Efficient strategy for the molecular diagnosis of intractable early-onset epilepsy using targeted gene sequencing
BMC MEDICAL GENOMICS 11/1 :6-,2018
Targeted gene panel and genotype-phenotype correlation in children with developmental and epileptic encephalopathy
EPILEPSY RESEARCH 141/ :48-55,2018
Detection of Germline Mutations in Patients with Epithelial Ovarian Cancer Using Multi-Gene Panels: Beyond BRCA1/2.
CANCER RESEARCH AND TREATMENT 50/3 :917-925,2018
The efficacy of ketogenic diet for specific genetic mutation in developmental and epileptic encephalopathy
FRONTIERS IN NEUROLOGY 9/JUL :530-538,2018
Difference in Risk of Breast and Ovarian Cancer According to Putative Functional Domain Regions in Korean BRCA1/2 Mutation Carriers.
CLINICAL BREAST CANCER 18/5 :362-373,2018
A patient with B-cell acute lymphoblastic leukemia with PAX5-ETV6 rearrangement with dic(9;12)(p13;p13) identified by chromosomal microarray
ANNALS OF HEMATOLOGY 97/8 :1,505-1,507,2018
Deletion of 20p13 and Duplication of 20p13p12.3 in a Patient with Delayed Speech and Development
ANNALS OF LABORATORY MEDICINE 38/1 :77-79,2018
SNP-based next-generation sequencing reveals low-level mixed chimerism after allogeneic hematopoietic stem cell transplantation
ANNALS OF HEMATOLOGY 97/9 :1,731-1,734,2018
Early Diagnosis of KBG Syndrome Using Diagnostic Exome Sequencing
Journal of the Korean Child Neurology Society(대한소아신경학회지) 26/4 :272-275,2018
Distinct Clinical Courses of Epithelial Ovarian Cancer with Mutations in BRCA1 5’ and 3’ Exons
ANTICANCER RESEARCH 38/12 :6,947-6,953,2018
FLT3 Internal Tandem Duplication in Patients With Acute Myeloid Leukemia Is Readily Detectable in a Single Next-Generation Sequencing Assay Using the Pindel Algorithm
ANNALS OF LABORATORY MEDICINE 39/3 :327-329,2019
Clinical Evaluation of Massively Parallel RNA Sequencing for Detecting Recurrent Gene Fusions in Hematologic Malignancies
JOURNAL OF MOLECULAR DIAGNOSTICS 21/1 :163-170,2019
Systematic evaluation of gene variants linked to hearing loss based on allele frequency threshold and filtering allele frequency
SCIENTIFIC REPORTS 9/1 :4583-,2019
The TECTA mutation R1890C is identified as one of the causes of genetic hearing loss: a case report
BMC MEDICAL GENETICS 20/1 :57-57,2019
Targeted next generation sequencing can serve as an alternative to conventional tests in myeloid neoplasms
PLOS ONE 14/3 :e0212228-,2019
A Child With Lymphangioma Due to Somatic Mutation in PIK3CA Successfully Treated With Everolimus
PEDIATRIC NEUROLOGY 91/ :65-67,2019
Somatic mosaic truncating mutations of PPM1D in blood can result from expansion of a mutant clone under selective pressure of chemotherapy
PLOS ONE 14/6 :e0217521-,2019
Next-generation sequencing with comprehensive bioinformatics analysis facilitates somatic mosaic APC gene mutation detection in patients with familial adenomatous polyposis
BMC MEDICAL GENOMICS 12/1 :103-,2019
A Somatic p.Phe29del Mutation of Connexin 26 (GJB2) Manifesting as Acantholytic Dyskeratotic Epidermal Nevus
JAMA DERMATOLOGY 155/5 :633-635,2019
Diagnostic challenge: Primary bone marrow diffuse large B-cell lymphoma mimicking systemic autoimmune disorders
Laboratory Medicine Online 9/4 :242-245,2019
Proband-Only Clinical Exome Sequencing for Neurodevelopmental Disabilities
PEDIATRIC NEUROLOGY 99/ :47-54,2019
Clinical Implementation of Targeted Gene Sequencing for Malformation of Cortical Development
PEDIATRIC NEUROLOGY 99/ :47-54,2019
Genetic and clinical features of SCN8A developmental and epileptic encephalopathy
EPILEPSY RESEARCH 158/1 :e106222-,2019
Mutant Thr95Ile Transthyretin-Related Cardiac Amyloidosis With Polyneuropathy
CIRCULATION JOURNAL 83/11 :2,328-2,328,2019
NUCLEIC ACIDS RESEARCH 43/5 :2590-2602,2015
NOTCH2 missplicing can occur in relation to apoptosis
BLOOD 126/14 :1731-1732,2015
Whole-genome fingerprint of the DNA methylome during human B cell differentiation
NATURE GENETICS 47/7 :746-746,2015
A subset of CD45+/CD19-cells in bone marrow may be associated with clinical outcomes of patients with mantle cell lymphoma
LEUKEMIA & LYMPHOMA 56/11 :3052-3057,2015
Genome-wide CpG island methylation and intergenic demethylation propensities vary among different tumor sites
NUCLEIC ACIDS RESEARCH 44/3 :1105-1117,2016
유전체 의학 시대를 맞이한 유전성 유방암-난소암 증후군 유전 검사의 임상적 함의: 임상의사가 바라본 전망
Journal of Breast Disease 4/1 :1-9,2016
Frequency and Clinical Characteristics of Intrachromosomal Amplification of Chromosome 21 in Korean Childhood B-lineage Acute Lymphoblastic Leukemia
ANNALS OF LABORATORY MEDICINE 36/5 :475-480,2016
Evaluation of an amplicon-based next-generation sequencing panel for detection of BRCA1 and BRCA2 genetic variants
BREAST CANCER RESEARCH AND TREATMENT 158/3 :433-440,2016
Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of DNMT3A mutations
ONCOTARGET 7/34 :54,825-54,837,2016
t(12;17)(p13;q12)/TAF15-ZNF384 Rearrangement in Acute Lymphoblastic Leukemia
ANNALS OF LABORATORY MEDICINE 36/4 :396-398,2016
Detection of MYD88 L265P in patients with lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia and other B-cell non-Hodgkin lymphomas
Blood Research 51/3 :181-186,2016
Usefulness of Flow Cytometric Analysis for Detecting Leptomeningeal Diseases in Non-Hodgkin Lymphoma
ANNALS OF LABORATORY MEDICINE 36/3 :209-214,2016
Chronic Myeloid Leukemia With Rare Variant b2a3 (e13a3) BCR-ABL1 Fusion
ANNALS OF LABORATORY MEDICINE 36/3 :287-289,2016
BRCA1 and BRCA2 mutation predictions using the BRCAPRO and Myriad models in Korean ovarian cancer patients
GYNECOLOGIC ONCOLOGY 145/1 :137-141,2017
Comparison of Clinical Outcomes of BRCA1/2 Pathologic Mutation, Variants of Unknown Significance, or Wild Type Epithelial Ovarian Cancer Patients
CANCER RESEARCH AND TREATMENT 49/2 :408-415,2017
Validation and Optimization of the Ion Torrent S5 XL Sequencer and Oncomine Workflow for BRCA1 and BRCA2 Genetic Testing
ONCOTARGET 8/21 :34,858-34,866,2017
Telomere length in alcohol dependence: A role for impulsive choice and childhood maltreatment
PSYCHONEUROENDOCRINOLOGY 83/ :72-78,2017
The effect of trauma and PTSD on telomere length: An exploratory study in people exposed to combat trauma
SCIENTIFIC REPORTS 7/1 :4375-,2017
Quinidine Trial in a Patient with Epilepsy of Infancy with Migrating Focal Seizure and KCNT1 Mutation
Journal of the Korean Child Neurology Society(대한소아신경학회지) 25/3 :169-173,2017
Identification of a Novel BRCA1 Pathogenic Mutation in Korean Patients Following Reclassification of BRCA1 and BRCA2 Variants According to the ACMG Standards and Guidelines Using Relevant Ethnic Controls
CANCER RESEARCH AND TREATMENT 49/4 :1,012-1,021,2017
Diagnostic application of clinical exome sequencing in Leber congenital amaurosis
MOLECULAR VISION 23/ :649-659,2017
Accuracy of Next-Generation Sequencing for Molecular Diagnosis in Patients With Infantile Nystagmus Syndrome
JAMA OPHTHALMOLOGY 135/12 :1376-1385,2017
Mowat-Wilson syndrome presenting with fever-associated seizures.
EPILEPTIC DISORDERS 19/4 :481-485,2017
Detection of Immunoglobulin Heavy Chain Gene Clonality by Next-Generation Sequencing for Minimal Residual Disease Monitoring in B-Lymphoblastic Leukemia
ANNALS OF LABORATORY MEDICINE 37/4 :331-335,2017
Efficacy of Stiripentol in Dravet Syndrome with or without SCN1A Mutations
JOURNAL OF CLINICAL NEUROLOGY 14/1 :22-28,2018
Application of Multiplex Ligation-Dependent Probe Amplification Assay for Genotyping Major Blood Group Systems Including DEL Variants in the D-Negative Korean Population
ANNALS OF LABORATORY MEDICINE 38/1 :32-38,2018
Variants of cancer susceptibility genes in Korean BRCA1/2 mutation-negative patients with high risk for hereditary breast cancer
BMC CANCER 18/1 :83-90,2018
Efficient strategy for the molecular diagnosis of intractable early-onset epilepsy using targeted gene sequencing
BMC MEDICAL GENOMICS 11/1 :6-,2018
Targeted gene panel and genotype-phenotype correlation in children with developmental and epileptic encephalopathy
EPILEPSY RESEARCH 141/ :48-55,2018
Detection of Germline Mutations in Patients with Epithelial Ovarian Cancer Using Multi-Gene Panels: Beyond BRCA1/2.
CANCER RESEARCH AND TREATMENT 50/3 :917-925,2018
The efficacy of ketogenic diet for specific genetic mutation in developmental and epileptic encephalopathy
FRONTIERS IN NEUROLOGY 9/JUL :530-538,2018
Difference in Risk of Breast and Ovarian Cancer According to Putative Functional Domain Regions in Korean BRCA1/2 Mutation Carriers.
CLINICAL BREAST CANCER 18/5 :362-373,2018
A patient with B-cell acute lymphoblastic leukemia with PAX5-ETV6 rearrangement with dic(9;12)(p13;p13) identified by chromosomal microarray
ANNALS OF HEMATOLOGY 97/8 :1,505-1,507,2018
Deletion of 20p13 and Duplication of 20p13p12.3 in a Patient with Delayed Speech and Development
ANNALS OF LABORATORY MEDICINE 38/1 :77-79,2018
SNP-based next-generation sequencing reveals low-level mixed chimerism after allogeneic hematopoietic stem cell transplantation
ANNALS OF HEMATOLOGY 97/9 :1,731-1,734,2018
Early Diagnosis of KBG Syndrome Using Diagnostic Exome Sequencing
Journal of the Korean Child Neurology Society(대한소아신경학회지) 26/4 :272-275,2018
Distinct Clinical Courses of Epithelial Ovarian Cancer with Mutations in BRCA1 5’ and 3’ Exons
ANTICANCER RESEARCH 38/12 :6,947-6,953,2018
FLT3 Internal Tandem Duplication in Patients With Acute Myeloid Leukemia Is Readily Detectable in a Single Next-Generation Sequencing Assay Using the Pindel Algorithm
ANNALS OF LABORATORY MEDICINE 39/3 :327-329,2019
Clinical Evaluation of Massively Parallel RNA Sequencing for Detecting Recurrent Gene Fusions in Hematologic Malignancies
JOURNAL OF MOLECULAR DIAGNOSTICS 21/1 :163-170,2019
Systematic evaluation of gene variants linked to hearing loss based on allele frequency threshold and filtering allele frequency
SCIENTIFIC REPORTS 9/1 :4583-,2019
The TECTA mutation R1890C is identified as one of the causes of genetic hearing loss: a case report
BMC MEDICAL GENETICS 20/1 :57-57,2019
Targeted next generation sequencing can serve as an alternative to conventional tests in myeloid neoplasms
PLOS ONE 14/3 :e0212228-,2019
A Child With Lymphangioma Due to Somatic Mutation in PIK3CA Successfully Treated With Everolimus
PEDIATRIC NEUROLOGY 91/ :65-67,2019
Somatic mosaic truncating mutations of PPM1D in blood can result from expansion of a mutant clone under selective pressure of chemotherapy
PLOS ONE 14/6 :e0217521-,2019
Next-generation sequencing with comprehensive bioinformatics analysis facilitates somatic mosaic APC gene mutation detection in patients with familial adenomatous polyposis
BMC MEDICAL GENOMICS 12/1 :103-,2019
A Somatic p.Phe29del Mutation of Connexin 26 (GJB2) Manifesting as Acantholytic Dyskeratotic Epidermal Nevus
JAMA DERMATOLOGY 155/5 :633-635,2019
Diagnostic challenge: Primary bone marrow diffuse large B-cell lymphoma mimicking systemic autoimmune disorders
Laboratory Medicine Online 9/4 :242-245,2019
Proband-Only Clinical Exome Sequencing for Neurodevelopmental Disabilities
PEDIATRIC NEUROLOGY 99/ :47-54,2019
Clinical Implementation of Targeted Gene Sequencing for Malformation of Cortical Development
PEDIATRIC NEUROLOGY 99/ :47-54,2019
Genetic and clinical features of SCN8A developmental and epileptic encephalopathy
EPILEPSY RESEARCH 158/1 :e106222-,2019
Mutant Thr95Ile Transthyretin-Related Cardiac Amyloidosis With Polyneuropathy
CIRCULATION JOURNAL 83/11 :2,328-2,328,2019
저서
저서 내용이 없습니다.
보도자료
"백혈병, 유전자검사로 예측할 수 있다"
http://v.media.daum.net/v/20190318180859467?f=o
세브란스 연구팀 "유전자 검사로 백혈병 위험 예측"
http://v.media.daum.net/v/20190318134040598?f=o
한국인 백혈병, 유전자 검사로 발생 위험 미리 알 수 있다
https://cp.news.search.daum.net/p/77300606
http://v.media.daum.net/v/20190318180859467?f=o
세브란스 연구팀 "유전자 검사로 백혈병 위험 예측"
http://v.media.daum.net/v/20190318134040598?f=o
한국인 백혈병, 유전자 검사로 발생 위험 미리 알 수 있다
https://cp.news.search.daum.net/p/77300606
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영상자료
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발표자료
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