연세대학교 의과대학 의학과 학사(1984) 연세대학교 대학원 의학과 석사(1991) 연세대학교 대학원 의학과(소아과학) 박사 (1995)
경력
1991-1993 소아내분비학 연구강사 1993-1995 이화의대 소아과학 전임강사 1995-1999 이화의대 소아과학 조교수 1999-2003 미국 Oregon Health & Science University 소아과 senior researcher 2003-2006 연세의대 소아과학교실 부교수 2007-현재 연세의대 소아과학교실 교수
*동아일보 선정 소아 질환분야 베스트 닥터(2000)
논문
2021 Ten-Year Trends of Metabolic Syndrome Prevalence and Nutrient Intake among Korean Children and Adolescents: A Population-Based Study YONSEI MEDICAL JOURNAL
2021 Prediction of Insulin Resistance by Modified Triglyceride Glucose Indices in Youth LIFE-BASEL
2021 Vitamin D status is associated with bone mineral density in adolescents: Findings from the Korea National Health and Nutrition Examination Survey NUTRITION RESEARCH
2021 Central precocious puberty may be a manifestation of endocrine dysfunction in pediatric patients with mitochondrial disease EUROPEAN JOURNAL OF PEDIATRICS
2020 Incidence and Prevalence of Type 1 Diabetes Mellitus among Korean Children and Adolescents between 2007 and 2017: An Epidemiologic Study Based on a National Database DIABETES & METABOLISM JOURNAL
2020 Cushing syndrome with acute kidney injury due to ureteral stones in a 6-year-old boy ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2020 Sex Hormone-Binding Globulin Is Associated with Obesity and Dyslipidemia in Prepubertal Children CHILDREN-BASEL
2020 Association of Vitamin D Status and Physical Activity with Lipid Profile in Korean Children and Adolescents: A Population-Based Study CHILDREN-BASEL
2020 Mitochondrial diabetes and mitochondrial DNA mutation load in MELAS syndrome EUROPEAN JOURNAL OF ENDOCRINOLOGY
2020 A case of primary hyperparathyroidism due to an intrathymic ectopic parathyroid adenoma in a 15-year-old boy ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2020 Effect of agricultural pesticide on precocious puberty in urban children: an exploratory study Clinical and Experimental Pediatrics
2020 Adolescents with thyroid nodules: retrospective analysis of factors predicting malignancy EUROPEAN JOURNAL OF PEDIATRICS
2019 Once-weekly supervised combined training improves neurocognitive and psychobehavioral outcomes in young patients with type 1 diabetes mellitus JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2019 A novel compound heterozygous mutation of the AIRE gene in a patient with autoimmune polyendocrine syndrome type 1 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2019 Healthcare Transition Readiness, Family Support, and Self-management Competency in Korean Emerging Adults with Type 1 Diabetes Mellitus JOURNAL OF PEDIATRIC NURSING-NURSING CARE OF CHILDREN & FAMILIES
2019 Final Adult Height after Growth Hormone Treatment in Patients with Turner Syndrome HORMONE RESEARCH IN PAEDIATRICS
2019 The analysis of endocrine disruptors in patients with central precocious puberty BMC PEDIATRICS
2019 제1형 당뇨병 청소년의 자기관리 영향요인: 정보-동기-행동기술 모델을 기반으로 Child Health Nursing Research
2019 Long-term safety and effectiveness of growth hormone therapy in Korean children with growth disorders: 5-year results of LG Growth Study PLOS ONE
2019 Incidence and Prevalence of Central Precocious Puberty in Korea: An Epidemiologic Study Based on a National Database JOURNAL OF PEDIATRICS
2018 Effect of the Orally Active Growth Hormone Secretagogue MK-677 on Somatic Growth in Rats YONSEI MEDICAL JOURNAL
2018 Recombinant growth hormone therapy for prepubertal children with idiopathic short stature in Korea: a phase III randomized trial. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
2018 Effect of Growth Hormone Therapy on Height Velocity in Korean Children with Idiopathic Short Stature: A Phase III Randomised Controlled Trial HORMONE RESEARCH IN PAEDIATRICS
2018 Respiratory failure in a diabetic ketoacidosis patient with severe hypophosphatemia ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2018 Visceral fat thickness and its associations with pubertal and metabolic parameters among girls with precocious puberty. ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2018 Once-Weekly Administration of Sustained-Release Growth Hormone in Korean Prepubertal Children with Idiopathic Short Stature: A Randomized, Controlled Phase II Study. HORMONE RESEARCH IN PAEDIATRICS
2017 A boy with 46,X,+mar presenting gynecomastia and short stature ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2017 Insulin resistance and bone age advancement in girls with central precocious puberty ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2017 A 1-month-old infant with chylomicronemia due to GPIHBP1 gene mutation treated by plasmapheresis ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2017 Clinical manifestations of Rathke's cleft cysts and their natural progression during 2 years in children and adolescents ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2017 Risk of Gonadoblastoma Development in Patients with Turner Syndrome with Cryptic Y Chromosome Material HORMONES & CANCER
2017 Diabetes mellitus due to agenesis of the dorsal pancreas in a patient with heterotaxy syndrome ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2017 Elevated serum YKL-40 levels in patients with Kawasaki disease BIOMARKERS
2017 Human Coronavirus in the 2014 Winter Season as a Cause of Lower Respiratory Tract Infection YONSEI MEDICAL JOURNAL
2016 Male patients presenting with rapidly progressive puberty associated with malignant tumors ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2016 A patient with Cushing disease lateralizing a pituitary adenoma by inferior petrosal sinus sampling using desmopressin: a case report ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2016 Ultrasound measurement of pediatric visceral fat thickness: correlations with metabolic and liver profiles ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2016 Burkholderia Sepsis in Children as a Hospital-Acquired Infection YONSEI MEDICAL JOURNAL
2015 XYY syndrome: a 13-year-old boy with tall stature ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2015 Hypotonic hyponatremia by primary polydipsia caused brain death in a 10-year-old boy ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2015 Clinical manifestations of testicular adrenal rest tumor in males with congenital adrenal hyperplasia ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2015 Turner syndrome with spinal hemorrhage due to vascular malformation ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2015 Relationship between serum 25-hydroxyvitamin D concentration and risks of metabolic syndrome in children and adolescents from Korean National Health and Nutrition Examination survey 2008-2010 ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2015 Etiologies and characteristics of children with chief complaint of short stature ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2015 Regression and progression of microalbuminuria in adolescents with childhood onset diabetes mellitus ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2015 Growth hormone treatment and risk of malignancy Korean Journal of Pediatrics
2014 Adult height in girls with central precocious puberty treated with gonadotropin-releasing hormone agonist with or without growth hormone ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2014 A case of thyrotoxic periodic paralysis as initial manifestation of Graves' disease in a 16-year-old Korean adolescent ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2014 KISS1 gene polymorphisms in Korean girls with central precocious puberty. JOURNAL OF KOREAN MEDICAL SCIENCE.
2014 Establishing pediatric reference intervals for 13 biochemical analytes derived from normal subjects in a pediatric endocrinology clinic in Korea. CLINICAL BIOCHEMISTRY
2014 Efficacy of Short-Term Growth Hormone Treatment in Prepubertal Children with Idiopathic Short Stature YONSEI MEDICAL JOURNAL
2013 Role of insulin-like growth factor binding protein-3 in glucose and lipid metabolism ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2013 Factors that predict a positive response on gonadotropin-releasing hormone stimulation test for diagnosing central precocious puberty in girls ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2013 Sex hormone binding globulin, free estradiol index, and lipid profiles in girls with precocious puberty ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2013 Efficacy and safety of LB03002, a once-weekly sustained-release human GH for 12-month treatment in Korean children with GH deficiency EUROPEAN JOURNAL OF ENDOCRINOLOGY
2013 Final height and insulin-like growth factor-1 in children with medulloblastoma treated with growth hormone CHILDS NERVOUS SYSTEM
2013 The Clinical Measures Associated with C-peptide Decline in Patients with Type 1 Diabetes over 15 Years JOURNAL OF KOREAN MEDICAL SCIENCE
2013 Longitudinal Standards for Height and Height Velocity in Korean Children and Adolescents: the Kangwha Cohort Study JOURNAL OF KOREAN MEDICAL SCIENCE
2013 IGFBP-3 Inhibits Cytokine-Induced Insulin Resistance and Early Manifestations of Atherosclerosis PLOS ONE
2012 Proton-Pump Inhibitor-Induced Hypocalcemia and Hypomagnesemia. ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2012 Hypodipsic hypernatremia leading to reversible renal failure following surgery for craniopharyngioma JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2012 Spot urine albumin to creatinine ratio and serum cystatin C are effective for detection of diabetic nephropathy in childhood diabetic patients JOURNAL OF KOREAN MEDICAL SCIENCE
2012 Reference values for serum levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in Korean children and adolescents. CLINICAL BIOCHEMISTRY
2012 Frequencies and Related Factors for Microvascular Complications in Patients with Type 1 Diabetes Complications in Patients with Type 1 Diabetes ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2011 Insulin-like growth factor-binding protein-3 mediates high glucose-induced apoptosis by increasing oxidative stress in proximal tubular epithelial cells. ENDOCRINOLOGY
2011 Serum kisspeptin levels in Korean girls with central precocious puberty JOURNAL OF KOREAN MEDICAL SCIENCE
2011 Noonan 증후군과 성장호르몬결핍증 환아에서 성장호르몬 치료 효과 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2010 Effects of Body Composition, Leptin, and Adiponectin on Bone Mineral Density in Prepubertal Girls JOURNAL OF KOREAN MEDICAL SCIENCE
2010 1형 당뇨병 소아환자에서 발생한 원발성 국소분절사구체경화증 1례 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2010 부갑상샘저하증과 거짓 부갑상샘저하증의 임상적 특성 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2010 Effects of a structured exercise program on insulin resistance, inflammatory markers and physical fitness in obese Korean children JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
2010 Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer JOURNAL OF BIOLOGICAL CHEMISTRY
2010 소아청소년 연령에서 발생한 2형 당뇨병의 항췌도 자가항체 유무에 따른 임상적 특성 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2010 RET proto-oncogene를 이용한 다발성 내분비 종양제 2B형의 조기진단으로 예방적 갑상선 절제술을 시행한 2례 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2010 An SRY-deleted XXY female resulting from a paternally inherited t(Y;22) ANNALS OF CLINICAL AND LABORATORY SCIENCE
2010 터너증후군에서 성장호르몬과 성호르몬 치료에 따른 인슐린 저항성의 변화 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2010 Insulin-like growth factor binding protein-3 induces G1 cell cycle arrest with inhibition of cyclin-dependent kinase 2 and 4 in MCF-7 human breast cancer cells. HORMONE AND METABOLIC RESEARCH
2010 Clinical application of gonadotropin-releasing hormone analogs in children and adolescents Korean Journal of Pediatrics
2009 Determination of Serum Di-(2-ethylhexyl) phthalate and Bisphenol A Level in Children with Idiopathic Central Precocious Puberty Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2009 1형 당뇨병 환자에서 생리주기 이상 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2009 소아 뇌종양 수술 후 수분대사 및 전해질 장애 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2008 당뇨병성 신증의 조기 예측 인자로서의 혈중 cystatin C 및 β2-microglobulin의 유용성 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2008 성조숙증의 진단과 최신 치료 경향 Endocrinology and Metabolism (대한내분비학회지)
2007 1형 당뇨병을 가진 소아과 청소년에서 란투스 치료의 혈당 조절에 대한 효과 Korean Journal of Pediatrics
2007 성조숙증 아동의 임상 및 내분비 검사의 특징 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2007 뇌종양 환아에서 성장호르몬 치료 후 뇌종양 재발증가에 관한 연구 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2007 Prevalence of the metabolic syndrome in Korean adolescents aged 12?19 years from the Korean National Health and Nutrition Examination Survey 1998 and 2001 DIABETES RESEARCH AND CLINICAL PRACTICE
2006 소아에서 혈중 아연 농도가 성장에 미치는 영향 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2006 조기 사춘기 여아에서 성선자극호르몬 분비호르몬 유도체가 성장과 성호르몬에 미치는 효과 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2006 Association of Henoch-Scho?nlein purpura and Graves' disease NEPHROLOGY DIALYSIS TRANSPLANTATION
2006 특발성 저신장증 환자에서 성장 호르몬 투여가 당 대사에 미치는 영향 Korean Journal of Pediatrics
2006 Obesity and Cardiovascular Risk Factors in Korean Children and Adolescents Aged 10?18 Years from the Korean National Health and Nutrition Examination Survey, 1998 and 2001 AMERICAN JOURNAL OF EPIDEMIOLOGY
2005 소아 비만증에서 비알코올성 지방간염의 유병률 Korean Journal of Pediatrics
2005 소아 및 청소년 비만증에서 인슐린 저항성에 미치는 요인 Korean Journal of Pediatrics
2005 한국인 선천성 부신피질과형성증의 임상적 특성 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2005 단순비만아에서 비만이 혈중 성장인자와 인슐린양성인자결합단백질-3의 단백분해에 미치는 영향 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2005 정상변이 염색체 다형현상과 동반된 저신장증 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2005 소아 및 청소년 비만증에서 인슐린 저항성의 성별 차이 Journal of Korean Society of Pediatric Endocrinology (대한소아내분비학회지)
2005 The abnormalities of carbohydrate metabolism in Turner syndrome: Analysis of risk factors associated with impaired glucose tolerance EUROPEAN JOURNAL OF PEDIATRICS
2004 Insulin-Like Growth Factor-Binding Protein 3 Induces Caspase-Dependent Apoptosis through a Death Receptor-Mediated Pathway in MCF-7 Human Breast Cancer Cells CANCER RESEARCH
2004 소아기 후천성 갑상선질환 Korean Journal of Pediatrics
2004 소아 제 2형 당뇨병 환아에서 Maturity Onset Diabetes of the Young(MODY) 3의 유병률에 관한 연구 Korean Journal of Pediatrics
2004 소아비만증에서 대사 증후군의 유병률 Korean Journal of Pediatrics
2004 성장호르몬 결핍증과 특발성 저신장증 환아에서 성장호르몬의 치료 효과 Korean Journal of Pediatrics