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  #위장관병리#분자병리

학력

2001 연세의대 졸,
2005년 연세대학원 박사 졸

경력

2004 : 연세 세브란스병원 인턴
2005-2008: 연세의료원 병리학 교실 전공의

논문

Concerted promoter hypermethylation of hMLH1, p16INK4A, and E-cadherin in gastric carcinomas with microsatellite instability. Kim H, Kim YH, Kim SE, Kim NG, Noh SH, Kim H. J Pathol. 2003;200:23-31.

Overexpression of high mobility group box 1 in gastrointestinal stromal tumors with KIT mutation. Choi YR, Kim H, Kang HJ, Kim NG, Kim JJ, Park KS, Paik YK, Kim HO, Kim H. Cancer Res. 2003;63:2188-93.

Different gene expression profiles between microsatellite instability-high and microsatellite stable colorectal carcinomas. Kim H, Nam SW, Rhee H, Shan Li L, Ju Kang H, Hye Koh K, Kyu Kim N, Song J, Tak-Bun Liu E, Kim H. Oncogene. 2004;23:6218-25.

Suppression of human selenium-binding protein 1 is a late event in colorectal carcinogenesis and is associated with poor survival. Kim H, Kang HJ, You KT, Kim SH, Lee KY, Kim TI, Kim C, Song SY, Kim HJ, Lee C, Kim H. Proteomics. 2006;6:3466-76.

Overexpression of high mobility group box 1 in gastrointestinal stromal tumors with KIT mutation
CANCER RESEARCH 63/9 :2188-2193,2003

Chromosomal imbalances in the colorectal carcinomas with microsatellite instability
AMERICAN JOURNAL OF PATHOLOGY 163/4 :1429-1436,2003

Complete Response of Recurrent Squamous Cell Carcinoma of the Lung: Dose the Dose Matter?
Journal Of Thoracic Oncology 4/1 :141-142,2009

TUMOR VOLUME CHANGES ASSESSED BY THREE-DIMENSIONAL MAGNETIC RESONANCE VOLUMETRY IN RECTAL CANCER PATIENTS AFTER PREOPERATIVE CHEMORADIATION: THE IMPACT OF THE VOLUME REDUCTION RATIO ON THE PREDICTION OF PATHOLOGIC COMPLETE RESPONSE
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 76/4 :1018-1025,2010

세포검사로 유두갑상샘암종이 의심되는 갑상샘 결절의 Galectin-3 발현과 BRAF 돌연변이 분석
The Korean Journal of Pathology 44/2 :191-198,2010

Effect of Helicobacter pylori infection on the sonic hedgehog signaling pathway in gastric cancer cells
Oncology Reports 23/6 :1523-1528,2010

Acquired resistance to cetuximab is mediated by increased PTEN instability and leads cross-resistance to gefitinib in HCC827 NSCLC cells.
Cancer Letters 296/2 :150-159,2010

Lymphoepithelial Cysts in the Pancreas: MRI of Two Cases With Emphasis of Diffusion-Weighted Imaging Characteristics
Journal Of Magnetic Resonance Imaging 32/3 :692-696,2010

Isolated Aspergillosis of the Brain in an Immunocompetent Patient: A Case Report
Journal Of The Korean Society Of Magnetic Resonance In Medicine(대한자기공명의과학회지) 14/1 :64-68,2010

Dose effect of cigarette smoking on frequency and spectrum of epidermal growth factor receptor gene mutations in Korean patients with non-small cell lung cancer
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 136/12 :1937-1944,2010

Local Recurrence of Secondary Hemangiosarcoma Following Breast Radiation Therapy: A Case Report
대한영상의학회지 63/6 :565-568,2010

Gene expression changes in patient-matched gastric normal mucosa, adenomas, and carcinomas
EXPERIMENTAL AND MOLECULAR PATHOLOGY 90/2 :201-209,2011

High microsatellite instability predicts good prognosis in intestinal-type gastric cancers
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 26/3 :585-592,2011

Lymphovascular invasion is an important predictor of lymph node metastasis in endoscopically resected early gastric cancers
ONCOLOGY REPORTS 25/ :1589-1595,2011

Cyclooxygenase-2 (COX-2) Expression in Solid Pseudopapillary Tumor of the Pancreas A Pilot Study
PANCREAS 40/1 :159-160,2011

Solitary Extrahepatic Intraabdominal Metastasis from Hepatocellular Carcinoma after Liver Transplantation
YONSEI MEDICAL JOURNAL 52/1 :199-203,2011

A Spinal Cord Astrocytoma and Its Concurrent Osteoblastic Metastases at the Time of the Initial Diagnosis: a Case Report and Literature Review
KOREAN JOURNAL OF RADIOLOGY 12/5 :620-625,2011

How to manage pyloric tumours that are difficult to resect completely with endoscopic resection: Comparison of the retroflexion vs. forward view technique
DIGESTIVE AND LIVER DISEASE 43/12 :958-964,2011

Synchronous double primary cancers associated with a choledochal cyst and anomalous pancreaticobiliary ductal union
JOURNAL OF THE KOREAN SURGICAL SOCIETY 81/4 :281-286,2011

A mathematical approach to the optimal examination of lymph nodes
APMIS 119/ :868-876,2011

Serous Cystic Neoplasm: Do We Have to Wait Till It Causes Trouble?
Korean Journal Of Hepato-Biliary-Pancreatic Surgery(한국간담췌외과학회지) 15/2 :134-138,2011

Tudor Domain-Containing Protein 4 as a Potential Cancer/Testis Antigen in Liver Cancer
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 224/1 :41-46,2011

Additive Lymph Node Dissection may be Necessary in Minute Submucosal Cancer of the Stomach after Endoscopic Resection.
ANNALS OF SURGICAL ONCOLOGY 19/ :779-785,2012

Human chorionic gonadotrophin regression rate as a predictive factor of postmolar gestational trophoblastic neoplasm in high-risk hydatidiform mole: A case-control study
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY 160/1 :100-105,2012

Safety evaluation of self-expanding metallic biliary stents eluting gemcitabine in a porcine model
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 27/2 :261-267,2012

Potential Contribution of Preoperative Neoadjuvant Concurrent Chemoradiation Therapy on Margin-Negative Resection in Borderline Resectable Pancreatic Cancer
JOURNAL OF GASTROINTESTINAL SURGERY 16/3 :509-517,2012

In Vitro Adenosine Triphosphate-Based Chemotherapy Response Assay (ATP-CRA) in Solid Pseudopapillary Tumor of the Pancreas
PANCREAS 41/3 :498-500,2012

Combination of radiotherapy and adenovirus-mediated p53 gene therapy for MDM2-overexpressing hepatocellular carcinoma
JOURNAL OF RADIATION RESEARCH 53/2 :202-210,2012

Prognostic Significance of Angiogenesis by Chalkley Counting in Node Negative Cancer of the Ampulla of Vater
JOURNAL OF KOREAN MEDICAL SCIENCE 27/5 :495-499,2012

Multifocality in Early Gastric Cancer Does not Increase the Risk of Lymph Node Metastasis in a Single-Center Study
ANNALS OF SURGICAL ONCOLOGY 19/4 :1251-1256,2012

Microsatellite instability in sporadic gastric cancer: its prognostic role and guidance for 5-FU based chemotherapy after R0 resection
INTERNATIONAL JOURNAL OF CANCER 131/2 :505-511,2012

Endoscopic and clinicopathologic characteristics of early gastric cancer with high microsatellite instability
WORLD JOURNAL OF GASTROENTEROLOGY 18/27 :3571-3577,2012

Ei24-deficiency attenuates protein kinase Cα signaling and skin carcinogenesis in mice
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 44/11 :1887-1896,2012

The diagnostic role of endoscopic submucosal dissection for gastric lesions with indefinite pathology
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY 47/ :1101-1107,2012

Second opinion in thyroid fine-needle aspiration biopsy by the Bethesda system
ENDOCRINE JOURNAL 59/3 :205-212,2012

Nuclear expression of Yes-associated protein 1 correlates with poor prognosis in intestinal type gastric cancer
ANTICANCER RESEARCH 32/9 :3827-3834,2012

Coexistence of Chronic Lymphocytic Thyroiditis with Papillary Thyroid Carcinoma: Clinical Manifestation and Prognostic Outcome
JOURNAL OF KOREAN MEDICAL SCIENCE 27/8 :883-889,2012

Serous cyst adenoma of the pancreas: Appraisal of active surgical strategy before it causes problems
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES 26/6 :1560-1565,2012

Ectopic pancreas with hemorrhagic cystic change in the anterior mediastinum
The Korean Journal of Thoracic and Cardiovascular Surgery 45/2 :131-133,2012

Ectopic Pancreas with Hemorrhagic Cystic Change in the Anterior Mediastinum
The Korean Journal of Thoracic and Cardiovascular Surgery 45/2 :131-133,2012

Circumferential Resection Margin Involvement in Stage III Rectal Cancer Patients Treated with Curative Resection Followed by Chemoradiotherapy: A Surrogate Marker for Local Recurrence?
YONSEI MEDICAL JOURNAL 54/1 :131-138,2013

Marginally Calcified Totally Necrotic Tumor of the Pancreas A Subset of SolidPseudopapillary Tumor With Near-Total Necrosis?
PANCREAS 42/1 :184-186,2013

Signet Ring Cell Mixed Histology May Show More Aggressive Behavior Than Other Histologies in Early Gastric Cancer
JOURNAL OF SURGICAL ONCOLOGY 107/2 :124-129,2013

Differential diagnosis between gallbladder adenomas and cholesterol polyps on contrast-enhanced harmonic endoscopic ultrasonography
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES 27/4 :1414-1421,2013

A Pilot Study for Preoperative Concurrent Chemoradiotherapy with S-1 and Cisplatin for Locally Advanced Gastric Cancer
HEPATO-GASTROENTEROLOGY 60/122 :382-386,2013

Identification and Selective Degradation of Neopeptide-Containing Truncated Mutant Proteins in the Tumors with High Microsatellite Instability
CLINICAL CANCER RESEARCH 19/13 :3369-3382,2013

Protein Kinase C-delta-Mediated Recycling of Active KIT in Colon Cancer
CLINICAL CANCER RESEARCH 19/18 :4961-4971,2013

Detection of the inflammatory process in a Behcet’s disease-like mouse model using 18F-fluorodeoxyglucose positron emission tomography
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 31/Suppl. :S47-S53,2013

Prognostic Value of Mucinous Histology Depends on Microsatellite Instability Status in Patients with Stage III Colon Cancer Treated with Adjuvant FOLFOX Chemotherapy: A Retrospective Cohort Study
ANNALS OF SURGICAL ONCOLOGY 20/11 :3407-3413,2013

Duodenum preserving pancreatic head resection in benign and low grade malignant pancreatic tumors
Korean Journal Of Hepato-Biliary-Pancreatic Surgery 17/3 :126-130,2013

Increased Expression of Yes-Associated Protein 1 in Hepatocellular Carcinoma with Stemness and Combined Hepatocellular-Cholangiocarcinoma
PLOS ONE 8/9 :e75449-,2013

Better Outcome of XELOX Chemotherapy in Patients with Advanced Intestinal-Type Adenocarcinoma of the Ampulla of Vater
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 231/ :21-28,2013

Can we apply the same indication of endoscopic submucosal dissection for primary gastric cancer to remnant gastric cancer?
GASTRIC CANCER 17/2 :310-315,2014

AFP-producing acinar cell carcinoma treated by pancreaticoduodenectomy in a patient with a previous radical subtotal gastrectomy by gastric cancer
Korean Journal Of Hepato-Biliary-Pancreatic Surgery 18/1 :33-37,2014

Pathologic Spectrum of Lymphocytic Infiltration and Recurrence of Papillary Thyroid Carcinoma
YONSEI MEDICAL JOURNAL 55/4 :879-885,2014

Clinicopathologic factors and outcomes of histologic discrepancy between differentiated and undifferentiated types after endoscopic resection of early gastric cancer
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES 28/7 :2097-2105,2014

Increased Expression of CCN2, Epithelial Membrane Antigen, and Fibroblast Activation Protein in Hepatocellular Carcinoma with Fibrous Stroma Showing Aggressive Behavior
PLOS ONE 9/8 :e 105094-,2014

Tumour size is related to the curability of signet ring cell early gastric cancer with endoscopic submucosal dissection: A retrospective single centre study
DIGESTIVE AND LIVER DISEASE 46/10 :898-902,2014

Clinical correlations with (18)FDG PET scan patterns in solid pseudopapillary tumors of the pancreas: Still a surgical enigma?
PANCREATOLOGY 14/6 :515-523,2014

High Expression of AT-Rich Interactive Domain 3A (ARID3A) is Associated with Good Prognosis in Colorectal Carcinoma
ANNALS OF SURGICAL ONCOLOGY Suppl 4/- :S481-S489,2014

Long Term Follow-Up and Characteristics of Cancer Negative Cases after Endoscopic Resection and Gastrectomy for Early Gastric Cancer
HEPATO-GASTROENTEROLOGY 61/135 :2133-2140,2014

Fibroblast growth factor receptor 1 gene amplification is associated with poor survival in patients with resected esophageal squamous cell carcinoma
ONCOTARGET 6/4 :2562-2572,2015

Clinical Implication of Highly Sensitive Detection of the BRAFV600E Mutation in Fine-Needle Aspirations According to the Thyroid Bethesda System in Patients With Conventional Papillary Thyroid Carcinoma
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY 124/5 :392-399,2015

Feasibility of terahertz reflectometry for discrimination of human early gastric cancers
BIOMEDICAL OPTICS EXPRESS 6/4 :1398-1406,2015

The different role of intratumoral and peritumoral lymphangiogenesis in gastric cancer progression and prognosis
BMC CANCER 15/498 :1501-1509,2015

담도유두종 환자에서 광역학치료 후 간용적 보존 수술 1예
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 66/1 :55-58,2015

Clinicopathological Features and Prognostic Significance of HER2 Expression in Gastric Cancer
ONCOLOGY 88/3 :147-156,2015

Usefulness of Immunohistochemistry for Microsatellite Instability Screening in Gastric Cancer
GUT AND LIVER 9/5 :629-635 ,2015

Prognostic Significance of Defining L-Cell Type on the Biologic Behavior of Rectal Neuroendocrine Tumors in Relation with Pathological Parameters
CANCER RESEARCH AND TREATMENT 47/4 :813-822,2015

Follicular variant of papillary thyroid carcinoma with B-type RafV600E showing higher frequency of suspicious sonographic features and multifocality
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK 37/11 :1590-1595,2015

Targeted therapy for Epstein-Barr virus-associated gastric carcinoma using low-dose gemcitabine-induced lytic activation
ONCOTARGET 6/31 :31018-31029,2015

Growth Patterns of Signet Ring Cell Carcinoma of the Stomach for Endoscopic Resection
GUT AND LIVER 9/6 :720-726,2015

Poorly Differentiated Carcinoma Component in Submucosal Layer Should be Considered as an Additional Criterion for Curative Endoscopic Resection of Early Gastric Cancer
ANNALS OF SURGICAL ONCOLOGY 22/Suppl :S772-S777,2015

Phase II clinical and exploratory biomarker study of dacomitinib in recurrent and/or metastatic esophageal squamous cell carcinoma
ONCOTARGET 6/42 :44971-44984,2015

Safety and feasibility of simultaneous endoscopic submucosal dissection for multiple gastric neoplasias
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES 29/12 :3690-3697,2015

Helicobacter pylori Eradication Reduces the Metachronous Recurrence of Gastric Neoplasms by Attenuating the Precancerous Process
Journal of Gastric Cancer 15/4 :246-255,2015

Differences in TGF-β1 signaling and clinicopathologic characteristics of histologic subtypes of gastric cancer
BMC CANCER 16/60 :1-7,2016

Establishment and characterisation of patient-derived xenografts as paraclinical models for gastric cancer
SCIENTIFIC REPORTS 6/22172 :1-12,2016

Are new criteria for mixed histology necessary for endoscopic resection in early gastric cancer?
PATHOLOGY RESEARCH AND PRACTICE 212/5 :410-414,2016

Is the recent WHO histological classification for gastric cancer helpful for application to endoscopic resection?
GASTRIC CANCER 19/3 :869-875,2016

PIK3CA amplification is associated with poor prognosis among patients with curatively resected esophageal squamous cell carcinoma
ONCOTARGET 7/21 :30691-30701,2016

Prognostic value of (18)F-fluorodeoxyglucose positron emission tomography in patients with gastric neuroendocrine carcinoma and mixed adenoneuroendocrine carcinoma
ANNALS OF NUCLEAR MEDICINE 30/4 :279-286,2016

Comprehensive expression profiles of gastric cancer molecular subtypes by immunohistochemistry: Implications for individualized therapy
ONCOTARGET 7/28 :44608-44620,2016

Prognostic significance and frequency of EGFR expression and amplification in surgically resected advanced gastric cancer
JAPANESE JOURNAL OF CLINICAL ONCOLOGY 46/6 :507-516,2016

Next-generation sequencing reveals somatic mutations that confer exceptional response to everolimus
ONCOTARGET 7/9 :10,547-10,556,2016

Clinicopathologic Features of Gastric Carcinoma With Lymphoid Stroma in Early Gastric Cancer
JOURNAL OF SURGICAL ONCOLOGY 114/6 :769-772,2016

Sex Disparity in Gastric Cancer: Female Sex is a Poor Prognostic Factor for Advanced Gastric Cancer
ANNALS OF SURGICAL ONCOLOGY 23/13 :4,344-4,351,2016

Pre- and post-ESD discrepancies in clinicopathologic criteria in early gastric cancer: the NECA-Korea ESD for Early Gastric Cancer Prospective Study (N-Keep)
GASTRIC CANCER 19/4 :1104-1113,2016

Receptor tyrosine kinase amplified gastric cancer: Clinicopathologic characteristics and proposed screening algorithm
ONCOTARGET 7/44 :72,099-72,112,2016

Epstein-Barr virus positivity, not mismatch repair-deficiency, is a favorable risk factor for lymph node metastasis in submucosa-invasive early gastric cancer
GASTRIC CANCER 19/4 :1,041-1,051,2016

Differential Prognostic Implications of Gastric Signet Ring Cell Carcinoma: Stage Adjusted Analysis From a Single High-volume Center in Asia
ANNALS OF SURGERY 265/5 :946-953,2017

Depth of response is a significant predictor for long-term outcome in advanced gastric cancer patients treated with trastuzumab.
ONCOTARGET 8/19 :31,169-31,179,2017

Complementary utility of targeted next-generation sequencing and immunohistochemistry panels as a screening platform to select targeted therapy for advanced gastric cancer
ONCOTARGET 8/24 :38,389-38,398,2017

Role of LOXL2 in the epithelial-mesenchymal transition and colorectal cancer metastasis
ONCOTARGET 8/46 :80,325-80,335,2017

Histologic purity of signet ring cell carcinoma is a favorable risk factor for lymph node metastasis in poorly cohesive, submucosa-invasive early gastric carcinoma
GASTRIC CANCER 20/4 :583-590,2017

Distinct expression profile of key molecules in crawling-type early gastric carcinoma
GASTRIC CANCER 20/4 :612-619,2017

CT features of hepatic metastases from hepatoid adenocarcinoma
ABDOMINAL RADIOLOGY 42/10 :2,402-2,409,2017

Probe-based confocal laser endomicroscopy in the margin delineation of early gastric cancer for endoscopic submucosal dissection.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 32/5 :1,046-1,054,2017

Experience-based surgical approach to pancreatic mucinous cystic neoplasms with ovarian-type stroma
ONCOLOGY LETTERS 15/2 :2,451-2,458,2018

Predictive test for chemotherapy response in resectable gastric cancer: a multi-cohort, retrospective analysis
LANCET ONCOLOGY 19/5 :629-638,2018

Inhibition of Wntless/GPR177 suppresses gastric tumorigenesis
BMB REPORTS 51/5 :255-260,2018

Prospective Single Arm Study on the Effect of Ilaprazole in Patients with Heartburn but No Reflux Esophagitis
YONSEI MEDICAL JOURNAL 59/8 :951-959,2018

MET in gastric cancer with liver metastasis: The relationship between MET amplification and Met overexpression in primary stomach tumors and liver metastasis
JOURNAL OF SURGICAL ONCOLOGY 117/8 :1,679-1,686,2018

Microsatellite instability test using peptide nucleic acid probe-mediated melting point analysis: a comparison study
BMC CANCER 18/ :1218-1227,2018

Role of probe-based confocal laser endomicroscopy-targeted biopsy in the molecular and histopathological study of gastric cancer
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 34/1 :84-91,2019

Phase II trial of preoperative sequential chemotherapy followed by chemoradiotherapy for high-risk gastric cancer
RADIOTHERAPY AND ONCOLOGY 140/ :143-149,2019

Immunohistochemistry Biomarkers Predict Survival in Stage II/III Gastric Cancer Patients: From a Prospective Clinical Trial
CANCER RESEARCH AND TREATMENT 51/2 :819-831,2019

Detection of Helicobacter pylori with clarithromycin resistance-associated mutations using peptide nucleic acid probe-based melting point analysis
HELICOBACTER 24/5 :e12634-,2019

Microsatellite Instability and Programmed Cell Death-Ligand 1 Expression in Stage II/III Gastric Cancer Post Hoc Analysis of the CLASSIC Randomized Controlled study
ANNALS OF SURGERY 270/2 :309-316,2019

Mesothelin Expression Is a Predictive Factor for Peritoneal Recurrence in Curatively Resected Stage III Gastric Cancer
ONCOLOGIST 24/11 :e1108-e1114,2019

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전이성 위암에 면역항암제 적용 "아직은 걸음마 단계"
https://cp.news.search.daum.net/p/78350668

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