김진석

교수
    

  #악성림프종#다발성골수종#조혈모세포이식#빈혈#출혈성질환#혈액종양

학력

연세의대 의학과 학사 (1996년)
연세의대 내과학 석사 (2001년)
연세의대 내과학 박사 (2004년)

경력

세브란스병원 내과 인턴
세브란스병원 내과 레지던트
세브란스병원 혈액종양내과 전임의
연세의대 혈액내과 전임강사 (2005년-2007년)
연세의대 혈액내과 조교수 (2007년-2011년)
연세의대 혈액내과 부교수 (2011년-2017년)
연세의대 혈액내과 교수 (2017년-현재)

논문

2021 Adaptive Natural Killer Cells Facilitate Effector Functions of Daratumumab in Multiple Myeloma CLINICAL CANCER RESEARCH

2021 Arsenic trioxide synergistically promotes the antileukaemic activity of venetoclax by downregulating Mcl-1 in acute myeloid leukaemia cells EXPERIMENTAL HEMATOLOGY & ONCOLOGY

2021 Different roles of surveillance positron emission tomography according to the histologic subtype of non-Hodgkin's lymphoma KOREAN JOURNAL OF INTERNAL MEDICINE

2020 Human herpesvirus 8-negative effusion-based lymphoma with indolent clinical behavior in an elderly patient: A case report and literature review ONCOLOGY LETTERS

2020 Intravenous busulfan and melphalan versus high-dose melphalan as a conditioning regimen for early autologous stem cell transplantation in patients with multiple myeloma: a propensity score-matched analysis LEUKEMIA & LYMPHOMA

2020 Increasing Incidence of B-Cell Non-Hodgkin Lymphoma and Occurrence of Second Primary Malignancies in South Korea: 10-Year Follow-up Using the Korean National Health Information Database CANCER RESEARCH AND TREATMENT

2020 Immunosuppressive role of CD11b + CD33 + HLA-DR - myeloid-derived suppressor cells-like blast subpopulation in acute myeloid leukemia CANCER MEDICINE

2020 Upfront autologous hematopoietic stem cell transplantation for high-risk patients with double-expressor diffuse large B cell lymphoma ANNALS OF HEMATOLOGY

2020 Association between sexuality knowledge and sexual dysfunction in hematopoietic stem cell transplantation patients and their partners PATIENT EDUCATION AND COUNSELING

2020 Busulfan, etoposide, cytarabine, and melphalan (BuEAM) as a conditioning regimen for autologous stem cell transplantation in patients with non-Hodgkin lymphoma (NHL) BONE MARROW TRANSPLANTATION

2020 Prognostic significance of interim PET/CT response for the treatment of advanced-stage marginal zone lymphoma in the post-rituximab era SCIENTIFIC REPORTS

2020 Autologous stem cell transplantation in elderly patients with multiple myeloma in Korea: the KMM1807 study INTERNATIONAL JOURNAL OF HEMATOLOGY

2020 Serum albumin and C-reactive protein as significant predictors of non-relapse mortality in lower gastrointestinal graft-versus-host disease ANNALS OF HEMATOLOGY

2020 ULK1 Inhibition as a Targeted Therapeutic Strategy for FLT3-ITD-mutated Acute Myeloid Leukemia JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

2020 Efficacy of Brentuximab Vedotin in Relapsed or Refractory High-CD30-Expressing Non-Hodgkin Lymphomas: Results of a Multicenter, Open-Labeled Phase II Trial CANCER RESEARCH AND TREATMENT

2020 PERK/NRF2 and Autophagy Form a Resistance Mechanism Against G9a Inhibition in Leukemia Stem Cells JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

2020 The complement C5 inhibitor crovalimab in paroxysmal nocturnal hemoglobinuria BLOOD

2019 Clinical Implication of Renal Dysfunction During the Clinical Course in Patients With Paroxysmal Nocturnal Hemoglobinuria: A Longitudinal Analysis ANNALS OF HEMATOLOGY

2019 후천성 혈우병 A Clinical and Experimental Thrombosis and Hemostasis

2019 국소적 대상포진이 발생한 면역저하환자로부터 유발된 수두의 발생 Korean Journal of Nosocomial Infection Control (병원감염관리)

2019 Early Cytomegalovirus Reactivation and Expansion of CD56brightCD16dim/-DNAM1+ Natural Killer Cells Are Associated with Antileukemia Effect after Haploidentical Stem Cell Transplantation in Acute Leukemia BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

2019 Induction of apoptosis and differentiation by Na/H exchanger 1 modulation in acute myeloid leukemia cells BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

2019 A Phase I/II, Open-Label, Prospective, Multicenter Study to Evaluate the Efficacy and Safety of Lower Doses of Bortezomib Plus Busulfan and Melphalan as a Conditioning Regimen in Patients with Multiple Myeloma Undergoing Autologous Peripheral Blood Stem Cell Transplantation: The KMM103 Study BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

2019 Long-term outcome, relapse patterns, and toxicity after radiotherapy for orbital mucosa-associated lymphoid tissue lymphoma: implications for radiotherapy optimization Japanese Journal of Clinical Oncology

2018 Phase 2 Study of an Intravenous Busulfan and Melphalan Conditioning Regimen for Autologous Stem Cell Transplantation in Patients with Multiple Myeloma (KMM150) BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

2018 HBsAg-Negative, Anti-HBc-Negative Patients Still Have a Risk of Hepatitis B Virus-Related Hepatitis after Autologous Stem Cell Transplantation for Multiple Myeloma or Malignant Lymphoma CANCER RESEARCH AND TREATMENT

2018 A prognostic scoring system for patients with multiple myeloma classified as stage II with the Revised International Staging System BRITISH JOURNAL OF HAEMATOLOGY

2017 Comprehensive Evaluation of the Revised International Staging System in Multiple Myeloma Patients Treated with Novel Agents as a Primary Therapy AMERICAN JOURNAL OF HEMATOLOGY

2017 Efficacy, pharmacokinetics, and safety of the biosimilar CT-P10 compared with rituximab in patients with previously untreated advanced-stage follicular lymphoma: a randomised, double-blind, parallel-group, non-inferiority phase 3 trial. LANCET HAEMATOLOGY

2017 Natural history of relapsed myeloma, refractory to immunomodulatory drugs and proteasome inhibitors: a multicenter IMWG study. LEUKEMIA

2017 A prospective, open-label, multicenter, observational study to evaluate the efficacy and safety of bortezomib-melphalan-prednisone as initial treatment for autologous stem cell transplantation-ineligible patients with multiple myeloma ONCOTARGET

2017 Improved prognostic stratification using NCCN- and GELTAMO-international prognostic index in patients with diffuse large B-cell lymphoma ONCOTARGET

2017 Clinical impact of early recovery of peripheral blood absolute lymphocyte count after frontline autologous stem cell transplantation for diffuse large B-cell lymphoma HEMATOLOGICAL ONCOLOGY

2017 Pretreatment Epstein-Barr virus DNA in whole blood is a prognostic marker in peripheral T-cell lymphoma ONCOTARGET

2017 The role of frontline autologous stem cell transplantation for primary plasma cell leukemia: a retrospective multicenter study (KMM160) ONCOTARGET

2017 Platelet to lymphocyte ratio (PLR) retains independent prognostic significance in advanced stage marginal zone lymphoma patients treated with rituximab, cyclophosphamide, vincristine, and prednisone combination chemotherapy (R-CVP): Consortium for Improving Survival of Lymphoma trial BLOOD RESEARCH

2017 Programmed cell death 1 expression is associated with inferior survival in patients with primary central nervous system lymphoma ONCOTARGET

2017 Efficacy of eculizumab in paroxysmal nocturnal hemoglobinuria patients with or without aplastic anemia: prospective study of a Korean PNH cohort BLOOD RESEARCH

2017 Clinical characteristics and treatment outcomes of isolated myeloid sarcoma without bone marrow involvement: a single-institution experience BLOOD RESEARCH

2017 Epidemiology and Risk Factors for Invasive Fungal Diseases among Allogeneic Hematopoietic Stem Cell Transplant Recipients in Korea: Results of "RISK" Study BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

2017 Factors associated with pulmonary toxicity after myeloablative conditioning using fractionated total body irradiation RADIATION ONCOLOGY JOURNAL

2017 Clinical outcomes in patients with diffuse large B cell lymphoma with a partial response to first-line R-CHOP chemotherapy: prognostic value of secondary International Prognostic Index scores and Deauville scores ANNALS OF HEMATOLOGY

2017 Hematopoietic stem cell mobilization: current status and future perspective BLOOD RESEARCH

2017 내과 전문의 시험제도의 발전방향 Korean Journal of Medicine

2017 Long-Term Follow-Up of Patients After Autologous Bone Marrow Cell Infusion for Decompensated Liver Cirrhosis CELL TRANSPLANTATION

2017 Prognostic significance of interventricular septal thickness in patients with AL amyloidosis LEUKEMIA RESEARCH

2017 AMPK-ULK1-Mediated Autophagy Confers Resistance to BET Inhibitor JQ1 in Acute Myeloid Leukemia Stem Cells CLINICAL CANCER RESEARCH

2017 Decitabine as a First-Line Treatment for Older Adults Newly Diagnosed with Acute Myeloid Leukemia YONSEI MEDICAL JOURNAL

2017 Targeting AMPK-ULK1-mediated autophagy for combating BET inhibitor resistance in acute myeloid leukemia stem cells. AUTOPHAGY

2017 The prognostic role of CD68 and FoxP3 expression in patients with primary central nervous system lymphoma ANNALS OF HEMATOLOGY

2016 Risk factors associated with early mortality in patients with multiple myeloma who were treated upfront with a novel agents containing regimen BMC CANCER

2016 A prognostic index for natural killer cell lymphoma after non-anthracycline-based treatment: a multicentre, retrospective analysis LANCET ONCOLOGY

2016 Minimal residual disease-based effect and long-term outcome of first-line dasatinib combined with chemotherapy for adult Philadelphia chromosome-positive acute lymphoblastic leukemia ANNALS OF ONCOLOGY

2016 Bendamustine in heavily pre-treated multiple myeloma patients: Results of a retrospective analysis from the Korean Multiple Myeloma Working Party BLOOD RESEARCH

2016 A phase II study of everolimus (RAD001), an mTOR inhibitor plus CHOP for newly diagnosed peripheral T-cell lymphomas ANNALS OF ONCOLOGY

2016 Psychometric analysis of the Korean version of the high-dose chemotherapy specific quality of life questionnaire module from the European Organization for Research and Treatment of Cancer (EORTC QLQ-HDC29) QUALITY OF LIFE RESEARCH

2016 A phase II study of oxaliplatin and prednisone for patients with relapsed or refractory marginal zone lymphoma: Consortium for Improving Survival of Lymphoma trial LEUKEMIA & LYMPHOMA

2016 Prognostic value of the inverse platelet to lymphocyte ratio (iPLR) in patients with multiple myeloma who were treated up front with a novel agent-containing regimen ANNALS OF HEMATOLOGY

2016 Efficacy and safety of micafungin versus intravenous itraconazole as empirical antifungal therapy for febrile neutropenic patients with hematological malignancies: a randomized, controlled, prospective, multicenter study ANNALS OF HEMATOLOGY

2016 Highly elevated serum lactate dehydrogenase is associated with central nervous system relapse in patients with diffuse large B-cell lymphoma: Results of a multicenter prospective cohort study ONCOTARGET

2016 The role of upfront autologous stem cell transplantation in high-risk younger patients with primary central nervous system lymphoma BRITISH JOURNAL OF HAEMATOLOGY

2016 Epstein-Barr virus reactivation in extranodal natural killer/T-cell lymphoma patients: a previously unrecognized serious adverse event in a pilot study with romidepsin ANNALS OF ONCOLOGY

2016 Daratumumab 투여를 받은 다발성 골수종 환자에서 비예기항체 동정검사상 범응집 소견을 보인 1예 Korean Journal of Blood Transfusion (대한수혈학회지)

2016 Clinical Practice Guidelines for the Management of Atypical Hemolytic Uremic Syndrome in Korea JOURNAL OF KOREAN MEDICAL SCIENCE

2016 The different roles of molecular classification according to upfront autologous stem cell transplantation in advanced-stage diffuse large B cell lymphoma patients with elevated serum lactate dehydrogenase ANNALS OF HEMATOLOGY

2016 The Roles of Radiotherapy and Chemotherapy in the Era of Multimodal Treatment for Early-Stage Nasal-Type Extranodal Natural Killer/T-Cell Lymphoma. YONSEI MEDICAL JOURNAL

2016 Selection of a mobilization regimen for multiple myeloma based on the response to induction therapy: granulocyte-colony stimulating factor (G-CSF) alone versus high-dose cyclophosphamide plus G-CSF. LEUKEMIA & LYMPHOMA

2016 Predictive Factors of Mortality in Population of Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH): Results from a Korean PNH Registry. JOURNAL OF KOREAN MEDICAL SCIENCE

2016 Prognostic factors for re-mobilization using plerixafor and granulocyte colony-stimulating factor (G-CSF) in patients with malignant lymphoma or multiple myeloma previously failing mobilization with G-CSF with or without chemotherapy: the Korean multicenter retrospective study. ANNALS OF HEMATOLOGY

2016 A new prognostic model using absolute lymphocyte count in patients with primary central nervous system lymphoma EUROPEAN JOURNAL OF CANCER

2016 Pretreatment Lymphopenia, Poor Performance Status, and Early Courses of Therapy Are Risk Factors for Severe Bacterial Infection in Patients with Multiple Myeloma during Treatment with Bortezomib-based Regimens JOURNAL OF KOREAN MEDICAL SCIENCE

2016 High pre-transplant serum ferritin and busulfan-thiotepa conditioning regimen as risk factors for hepatic sinusoidal obstructive syndrome after autologous stem cell transplantation in patients with malignant lymphoma. LEUKEMIA & LYMPHOMA

2016 Distinct subgroups of paroxysmal nocturnal hemoglobinuria (PNH) with cytopenia: results from South Korean National PNH Registry ANNALS OF HEMATOLOGY

2015 Mutations in the Spliceosomal Machinery Genes SRSF2, U2AF1, and ZRSR2 and Response to Decitabine in Myelodysplastic Syndrome. ANTICANCER RESEARCH

2015 Clinical Outcomes and Prognostic Factors of Up-Front Autologous Stem Cell Transplantation in Patients with Extranodal Natural Killer/T Cell Lymphoma. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

2015 Use of lenalidomide in the management of relapsed or refractory multiple myeloma: expert recommendations in Korea. BLOOD RESEARCH

2015 Clinical outcome and prognosis of patients with primary sinonasal tract diffuse large B-cell lymphoma treated with rituximab-cyclophosphamide, doxorubicin, vincristine and prednisone chemotherapy: a study by the Consortium for Improving Survival of Lymphoma. LEUKEMIA & LYMPHOMA

2015 Intraocular lymphoma in Korea: the Consortium for Improving Survival of Lymphoma (CISL) study BLOOD RESEARCH

2015 Radiotherapy as an effective treatment modality for follicular lymphoma: a single institution experience RADIATION ONCOLOGY JOURNAL

2015 Induction of cytosine arabinoside-resistant human myeloid leukemia cell death through autophagy regulation by hydroxychloroquine BIOMEDICINE & PHARMACOTHERAPY

2015 Multicenter analysis of treatment outcomes in adult patients with lymphoblastic lymphoma who received hyper-CVAD induction followed by hematopoietic stem cell transplantation ANNALS OF HEMATOLOGY

2015 The effect of bortezomib on expression of inflammatory cytokines and survival in a murine sepsis model induced by cecal ligation and puncture YONSEI MEDICAL JOURNAL

2015 Early CMV replication and subsequent chronic GVHD have a significant anti-leukemic effect after allogeneic HSCT in acute myeloid leukemia ANNALS OF HEMATOLOGY

2015 Efficacy and safety of ruxolitinib in Asian patients with myelofibrosis LEUKEMIA & LYMPHOMA

2014 Changes in Osteoblastic Activity in Patient Who Received Bortezomib as Second Line Treatment for Plasma Cell Myeloma: A Prospective Multicenter Study BIOMED RESEARCH INTERNATIONAL

2014 Clinical factors associated with response or survival after chemotherapy in patients with Waldenstrom macroglobulinemia in Korea BIOMED RESEARCH INTERNATIONAL

2014 The modified Glasgow Prognostic Scores as a predictor in diffuse large B cell lymphoma treated with R-CHOP regimen YONSEI MEDICAL JOURNAL

2014 Clinical characteristics, pathological distribution, and prognostic factors in non-Hodgkin lymphoma of Waldeyer's ring: nationwide Korean study. KOREAN JOURNAL OF INTERNAL MEDICINE

2014 Clinical profiles of multiple myeloma in Asia-An Asian Myeloma Network study. AMERICAN JOURNAL OF HEMATOLOGY

2014 Chromosome 13 deletion and hypodiploidy on conventional cytogenetics are robust prognostic factors in Korean multiple myeloma patients: web-based multicenter registry study ANNALS OF HEMATOLOGY

2014 Busulfan-containing conditioning regimens are optimal preparative regimens for autologous stem cell transplant in patients with diffuse large B-cell lymphoma. LEUKEMIA & LYMPHOMA

2014 Lenalidomide with dexamethasone treatment for relapsed/refractory myeloma patients in Korea-experience from 110 patients ANNALS OF HEMATOLOGY

2014 Concurrent chemoradiotherapy followed by L-asparaginase-containing chemotherapy, VIDL, for localized nasal extranodal NK/T cell lymphoma: CISL08-01 phase II study ANNALS OF HEMATOLOGY

2014 The role of radiotherapy in the management of POEMS syndrome. RADIATION ONCOLOGY

2014 Gemcitabine-Induced Hemolytic Uremic Syndrome in Pancreatic Cancer: A Case Report and Review of the Literature GUT AND LIVER

2014 Monoclonal and polyclonal gammopathy measured by serum free light chain and immunofixation subdivide the clinical outcomes of diffuse large B-cell lymphoma according to molecular classification ANNALS OF HEMATOLOGY

2014 Serum microRNA-21 as a potential biomarker for response to hypomethylating agents in myelodysplastic syndromes PLOS ONE

2014 Early response to high-dose methotrexate, vincristine, and procarbazine chemotherapy-adapted strategy for primary CNS lymphoma: no consolidation therapy for patients achieving early complete response. ANNALS OF HEMATOLOGY

2014 High-Dose Etoposide Plus Granulocyte Colony-Stimulating Factor as an Effective Chemomobilization Regimen for Autologous Stem Cell Transplantation in Patients with Non-Hodgkin Lymphoma Previously Treated with CHOP-based Chemotherapy: A Study from the Consortium for Improving Survival of Lymphoma BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

2014 Clinical Outcomes and Prognostic Factors of Empirical Antifungal Therapy with Itraconazole in the Patients with Hematological Malignancies: A Prospective Multicenter Observational Study in Korea YONSEI MEDICAL JOURNAL

외 90여개

저서

저서 내용이 없습니다.

보도자료

"`벤클렉스타` 치료 후, 말 그대로 '기적'이 일어났죠" '2년'이라는 '고정기간 치료' 도입, 완전히 바뀐 환경
http://medipana.com/news/news_viewer.asp?NewsNum=258201&MainKind=A&NewsKind=5&vCount=12&vKind=1

노인에게 흔한 혈액암 '다발골수종' 주요 의심 증상은…
http://health.chosun.com/site/data/html_dir/2020/02/28/2020022801852.html

노년기 복병 ‘다발골수종’, 다양해진 치료제로 ‘희망’을 낚다
http://news.khan.co.kr/kh_news/khan_art_view.html?artid=201911151415002&code=900303#csidx6d9d4241fbb3e09bc283a2128f2c9f5

[Health] 30·40대 여성 불청객 `빈혈` 어지러울 때만 걱정하셨죠?
https://www.mk.co.kr/news/special-edition/view/2015/06/591875/

혈액암 항체 치료 효과 메커니즘 밝혀
https://www.hankookilbo.com/News/Read/A2021051422480005531?did=NA

다발성 골수종 환자 항체치료 반응 매개·예측 기전 확인
http://www.munhwa.com/news/view.html?no=2021051301031603311002

포스팅

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영상자료

[KBDCA 한국혈액암협회] [웨비나Talk] "다발골수종의 이해" / 다발골수종의 진단 및 임상양상과 질의응답 (서울성모병원 민창기 교수/ 세브란스병원 김진석 교수)
https://www.youtube.com/watch?v=85p8DPCsYHE

[KBDCA 한국혈액암협회] [웨비나] "발작야간혈색소뇨증의 이해와 치료" / PNH 치료에 사용되는 치료요법 (세브란스병원 김진석 교수)
https://www.youtube.com/watch?v=4cEF1eDSpgU

발표자료

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