연세대학교 대학원 의학박사(2000) 연세대학교 대학원 의학석사(1995) 연세대학교 의과대학 의학사(1988)
경력
2016.3-2020.2 연세의대 이비인후과학교실 주임교수 2016.3-2020.2 연세의대 신촌세브란스병원 이비인후과 과장 2015.3-2021.2 연세암병원 두경부암센터장 2011.3-현재 연세의대 이비인후과학교실 교수 2009.2 Transoral Robotic surgery course (Advanced Course) Certification of Console surgeon University of Pennsylvania, USA 2008.2 Transoral Robotic surgery course (Basic course) University of Pennsylvania, USA 2003.5-2005.4 Memorial Sloan-Kettering Cancer Center, New York. USA. Visiting Investigator 2006.3-2010.2 연세의대 이비인후과학교실 부교수 2000.4-2006.2 연세의대 이비인후과학교실 조교수 1998.4-2000.3 Memorial Sloan-Kettering Cancer Center Research Fellow 1995.10-1995.11 일본 동경대학 Visiting Researcher 1995.5- 1998.3 연세의대 이비인후과학교실 강사
논문
2021 Postoperative Concurrent Chemoradiotherapy Versus Radiotherapy Alone for Advanced Oral Cavity Cancer in the Era of Modern Radiation Techniques FRONTIERS IN ONCOLOGY
2021 Comprehensive Analysis of Clinicopathologic Factors Predictive of an Unfavorable Prognosis in Patients With Acinic Cell Carcinoma of the Parotid Gland CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY
2020 Mouse-human co-clinical trials demonstrate superior anti-tumour effects of buparlisib (BKM120) and cetuximab combination in squamous cell carcinoma of head and neck BRITISH JOURNAL OF CANCER
2020 Clinical-pathological prognostic factors and treatment failure patterns in T1-2 high-grade parotid gland cancer ORAL ONCOLOGY
2020 Comparison of Surgical Outcomes of Robotic and Conventional Approaches in Patients with Pre- and Poststyloid Parapharyngeal Space Tumors ANNALS OF SURGICAL ONCOLOGY
2020 Surgical extent and role of adjuvant radiotherapy of surgically resectable, low-grade parotid cancer ORAL ONCOLOGY
2020 Prognostic significance of lymphovascular invasion in patients with salivary duct cell carcinoma of the head and neck INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
2020 Molecular subtypes of oropharyngeal cancer show distinct immune microenvironment related with immune checkpoint blockade response BRITISH JOURNAL OF CANCER
2020 Real impact of surgical robotic system for precision surgery of parotidectomy: retroauricular parotidectomy using da Vinci surgical system GLAND SURGERY
2020 ICG-Guided Sentinel Lymph Node Sampling during Robotic Retroauricular Neck Dissection in cN0 Oral Cancer OTOLARYNGOLOGY-HEAD AND NECK SURGERY
2019 Transoral robotic surgery in patients with stage III/IV hypopharyngeal squamous cell carcinoma: treatment outcome and prognostic factor ACTA OTO-LARYNGOLOGICA
2019 Gasless transoral robotic thyroidectomy using the DaVinci SP system: Feasibility, safety, and operative technique ORAL ONCOLOGY
2019 The First Human Trial of Transoral Robotic Surgery Using a Single-Port Robotic System in the Treatment of Laryngo-Pharyngeal Cancer ANNALS OF SURGICAL ONCOLOGY
2019 Transoral Robotic Surgery With Transoral Retropharyngeal Lymph Node Dissection in Patients With Tonsillar Cancer: Anatomical Points, Surgical Techniques, and Clinical Usefulness. JOURNAL OF CRANIOFACIAL SURGERY
2019 Does p16+ Predict a Favorable Prognosis for Oropharyngeal Cancer? Risk Factors for Treatment Failure for Patients Who Underwent Surgery-Based Therapy ANNALS OF SURGICAL ONCOLOGY
2018 Elective neck treatment in clinically node-negative paranasal sinus carcinomas: impact on treatment outcome RADIATION ONCOLOGY JOURNAL
2018 Survival and Functional Outcome after Treatment for Primary Base of Tongue Cancer: A Comparison of Definitive Chemoradiotherapy versus Surgery Followed by Adjuvant Radiotherapy. CANCER RESEARCH AND TREATMENT
2018 Lymph Node With the Highest FDG Uptake Predicts Distant Metastasis-Free Survival in Patients With Locally Advanced Nasopharyngeal Carcinoma CLINICAL NUCLEAR MEDICINE
2018 A Clinical Trial of Combination Neoadjuvant Chemotherapy and Transoral Robotic Surgery in Patients with T3 and T4 Laryngo-Hypopharyngeal Cancer ANNALS OF SURGICAL ONCOLOGY
2018 Radiotherapy Versus Cordectomy in the Management of Early Glottic Cancer CANCER RESEARCH AND TREATMENT
2017 Tumor Stage-Related Role of Radiotherapy in Patients with an External Auditory Canal and Middle Ear Carcinoma CANCER RESEARCH AND TREATMENT
2017 Transoral robotic surgery-based therapy in patients with stage III-IV oropharyngeal squamous cell carcinoma ORAL ONCOLOGY
2017 A New Clinical Trial of Neoadjuvant Chemotherapy Combined With Transoral Robotic Surgery and Customized Adjuvant Therapy for Patients With T3 or T4 Oropharyngeal Cancer ANNALS OF SURGICAL ONCOLOGY
2017 The long-term oncological and functional outcomes of transoral robotic surgery in patients with hypopharyngeal cancer ORAL ONCOLOGY
2016 The Settings, Pros and Cons of the New Surgical Robot da Vinci Xi System for Transoral Robotic Surgery (TORS): A Comparison With the Popular da Vinci Si System SURGICAL LAPAROSCOPY ENDOSCOPY & PERCUTANEOUS TECHNIQUES
2016 Impact of p16 expression in oropharyngeal cancer in the postoperative setting: the necessity of re-evaluating traditional risk stratification JAPANESE JOURNAL OF CLINICAL ONCOLOGY
2016 Prognostic value of FDG-PET volumetric parameters in patients with p16-positive oropharyngeal squamous cell carcinoma who received curative resection followed by postoperative radiotherapy or chemoradiotherapy HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
2016 Role of cancer stem cell in radioresistant head and neck cancer AURIS NASUS LARYNX
2016 Application of dynamic contrast-enhanced MRI parameters for differentiating squamous cell carcinoma and malignant lymphoma of the oropharynx AMERICAN JOURNAL OF ROENTGENOLOGY
2016 Definitive Chemoradiotherapy Versus Surgery Followed by Adjuvant Radiotherapy in Resectable Stage III/IV Hypopharyngeal Cancer CANCER RESEARCH AND TREATMENT
2015 Lateral Oropharyngeal Wall Coverage with Buccinator Myomucosal and Buccal Fat Pad Flaps Archives of Plastic Surgery
2014 Postoperative radiotherapy in salivary ductal carcinoma: a single institution experience RADIATION ONCOLOGY JOURNAL
2014 Comparison of oncologic and functional outcomes after transoral robotic lateral oropharyngectomy versus conventional surgery for T1 to T3 tonsillar cancer. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
2013 Robotic Resection of Benign Neck Masses via a Retroauricular Approach JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES
2013 Characteristics, management of the neck, and oncological outcomes of malignant minor salivary gland tumours in the oral and sinonasal regions. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY
2013 Diagnosis and surgical outcomes of intraparotid facial nerve schwannoma showing normal facial nerve function INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
2013 The Efficacy of the Harmonic Scalpel in Neck Dissection: A Prospective Randomized Study LARYNGOSCOPE
2013 Comparison study of transoral robotic surgery and radical open surgery for hypopharyngeal cancer ACTA OTO-LARYNGOLOGICA
2013 Selective Neck Dissection for Clinically Node-Positive Oral Cavity Squamous Cell Carcinoma YONSEI MEDICAL JOURNAL
2013 Therapeutic Effect of Oncolytic Adenovirus Expressing Relaxin in Radioresistant Oral Squamous Cell Carcinoma ONCOLOGY RESEARCH
2013 Comparison of treatment outcomes after transoral robotic surgery and supraglottic partial laryngectomy: Our experience with seventeen and seventeen patients respectively CLINICAL OTOLARYNGOLOGY
2013 Oncological and functional outcomes of transoral robotic surgery for oropharyngeal cancer BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY
2013 A Novel Technique for the Resection of the Symptomatic Lingual Thyroid: Transoral Robotic Surgery THYROID
2013 How to optimize laryngeal and hypopharyngeal exposure in transoral robotic surgery AURIS NASUS LARYNX
2013 Parapharyngeal Space Surgery via a Transoral Approach Using a Robotic Surgical System: Transoral Robotic Surgery JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES
2013 Surgical techniques and treatment outcomes of transoral robotic supraglottic partial laryngectomy LARYNGOSCOPE
2013 Clinical outcomes of transoral robotic surgery for head and neck tumors ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
2013 Identifying genes related to radiation resistance in oral squamous cell carcinoma cell lines INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
2012 Transoral robotic surgery for hypopharyngeal squamous cell carcinoma: 3-year oncologic and functional analysis ORAL ONCOLOGY
2012 Transoral Robotic Surgery: Technical Review and Postoperative Imaging Findings
2012 Radiotherapy deteriorates postoperative functional outcome after partial glossectomy with free flap reconstruction JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
2012 Robotic sialoadenectomy of the submandibular gland via a modified face-lift approach. INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
2012 Preoperative imaging evaluation of head and neck cancer: Comparison of 2D spin-echo and 3D THRIVE MRI techniques with resected tumours CLINICAL RADIOLOGY
2012 Transoral robotic surgery for the resection of parapharyngeal tumour: Our experience in ten patients CLINICAL OTOLARYNGOLOGY
2012 The efficacy and toxicity of S-1 and cisplatin as first-line chemotherapy in recurrent or metastatic head and neck squamous cell carcinoma. CANCER CHEMOTHERAPY AND PHARMACOLOGY
2011 Is human papillomavirus a causative factor of glottic cancer? JOURNAL OF VOICE
2011 Expression of matrix metalloproteinases and their inhibitors in squamous cell carcinoma of the tonsil and their clinical significance CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY
2011 Necessity of level IV dissection in cN0 hypopharyngeal carcinoma ACTA OTO-LARYNGOLOGICA
2011 Nuclear localization of Nm23-H1 in head and neck squamous cell carcinoma is associated with radiation resistance. CANCER
2011 Sonographically guided fine-needle aspiration biopsy of major salivary gland masses: a review of 245 cases AMERICAN JOURNAL OF ROENTGENOLOGY
2010 Radiology quiz case 1. Chronic sclerosing sialadenitis of the submandibular gland ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
2010 The oncologic safety and functional preservation of supraglottic partial laryngectomy AMERICAN JOURNAL OF OTOLARYNGOLOGY
2010 Successful decannulation of T-tubes according to type of tracheal stenosis. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
2010 Relevance of human papilloma virus (HPV) infection to carcinogenesis of oral tongue cancer. INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
2010 Feasiblity of transoral robotic hypopharyngectomy for early-stage hypopharyngeal carcinoma ORAL ONCOLOGY
2010 Predictive factors of isolated distant metastasis after primary definitive surgery without systemic treatment for head and neck squamous cell carcinoma ORAL ONCOLOGY
2010 Factors predictive of successful outcome following salvage treatment of isolated neck recurrences OTOLARYNGOLOGY-HEAD AND NECK SURGERY
2010 Extranodal nasal-type NK/T-cell lymphoma: computed tomography findings of head and neck involvement ACTA RADIOLOGICA
2009 경구강 로봇을 이용하여 시행한 근치적 편도암 절제술 1예 Korean Journal of Otorhinolaryngology-Head and Neck Surgery
2009 경구강 로봇을 이용해 시행한 근치적 하인두암 이상와 절제술 1례 Korean Journal of Head & Neck Oncology (대한두경부종양학회지)
2009 두경부 편평세포암종의 발암 원인으로 인간유두종 바이러스(Human Papilloma Virus)의 역할 및 이와 관련된 발암 기전에 관한 연구 Korean Journal of Head & Neck Oncology (대한두경부종양학회지)
2009 로봇 수술 시스템을 이용한 두경부 수술 Korean Journal of Otorhinolaryngology-Head and Neck Surgery
2009 Weekly docetaxel in patients with platinum-refractory metastatic or recurrent squamous cell carcinoma of the head and neck CANCER CHEMOTHERAPY AND PHARMACOLOGY
2009 Significant invasion depth of early oral tongue cancer originated from the lateral border to predict regional metastases and prognosis INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
2009 Transoral robotic surgery (TORS) in laryngeal and hypopharyngeal cancer JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES
2009 Feasibility of transoral lateral oropharyngectomy using a robotic surgical system for tonsillar cancer ORAL ONCOLOGY
2008 Effect of human papilloma virus expression on clinical course of laryngeal papilloma ACTA OTO-LARYNGOLOGICA
2008 방사선 치료 중인 두경부 종양 환자를 대상으로 메게이스 내복 현탁액 경구투여 후 유효성 및 안전성에 관한 다기관, 공개, 관측연구 Korean Journal of Head & Neck Oncology (대한두경부종양학회지)
2008 급격한 전신 전이 양상을 보인 편도에 발생한 소세포암종 1예 Korean Journal of Otolaryngology (대한이비인후과학회지)
2008 하인두암에서 후두인두 및 경부 식도 전 적출술 후 유리 공장 이식술의 합병증에 대한 후향적 분석 Korean Journal of Head & Neck Oncology (대한두경부종양학회지)
2007 두경부에 발생한 육종의 임상적 고찰 Korean Journal of Head & Neck Oncology (대한두경부종양학회지)
2007 Role of p53 in antioxidant defense of HPV-positive cervical carcinoma cells following H2O2 exposure JOURNAL OF CELL SCIENCE
2007 HPV integration begins in the tonsillar crypt and leads to the alteration of p16, EGFR and c-myc during tumor formation INTERNATIONAL JOURNAL OF CANCER
2006 헤르페스 바이러스를 이용한 두경부암의 유전자 치료 Korean Journal of Otolaryngology (대한이비인후과학회지)
2006 방사선 치료에 내성이 유도된 두경부 편평세포암에 대한 종양살상 헤르페스 바이러스의 유전자 치료 효과 Korean Journal of Head & Neck Oncology (대한두경부종양학회지)
2006 Lymphatic metastases to level IIb in hypopharyngeal squamous cell carcinoma ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
2006 Management of contralateral N0 neck in pyriform sinus carcinoma LARYNGOSCOPE
2006 Correlations of oral tongue cancer invasion with matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) expression JOURNAL OF SURGICAL ONCOLOGY
2006 Treatment of contralateral N0 neck in early squamous cell carcinoma of the oral tongue: Elective neck dissection versus observation LARYNGOSCOPE
2005 Management of Contralateral N0 Neck in Tonsillar Squamous Cell Carcinoma LARYNGOSCOPE
2005 Matrix Metalloproteinases(MMPs) 및 Vascular Endothelial Growth Factor(VEGF)의 발현을 통한 구강 설암의 침윤 기전 연구 Korean Journal of Head & Neck Oncology (대한두경부종양학회지)
2005 Combination of mutated herpes simplex virus type 1 (G207 virus) with radiation for the treatment of squamous cell carcinoma of the head and neck EUROPEAN JOURNAL OF CANCER
2004 30년 이상 비강, 부비동 및 안와에 존재한 금속 이물 1예 Korean Journal of Otolaryngology (대한이비인후과학회지)
2003 Changes of Esophageal Motility after Total Laryngectomy OTOLARYNGOLOGY-HEAD AND NECK SURGERY
2002 선천성 식도폐쇄에서 발생한 선천성 기관연화 Journal of the Korean Association of Pediatric Surgeons (소아외과)
2002 Mucociliary differentiation according to time in human nasal epithelial cell culture DIFFERENTIATION
2001 A Novel Approach to Cancer Therapy Using an Oncolytic Herpes Virus to Package Amplicons Containing Cytokine Genes MOLECULAR THERAPY
2001 설근부암의 수술적 접근방법과 재건방법의 선택 Korean Journal of Otolaryngology (대한이비인후과학회지)
2001 Cytokine Gene Transfer Enhances Herpes Oncolytic Therapy in Murine Squamous Cell Carcinoma HUMAN GENE THERAPY
2001 Effective treatment of head and neck squamous cell carcinoma by an oncolytic herpes simplex virus JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
2001 두경부암 유전자치료의 현황과 전망 Korean Journal of Otolaryngology (대한이비인후과학회지)
2000 Genome-wide screening for radiation response factors in head and neck cancer Laryngoscope
2000 성문상 부분 후두절제술 후 인후두의 봉합방법에 따른 술후기능과 합병증에 관한 고찰 Korean Journal of Otolaryngology (대한이비인후과학회지)
2000 하인두 및 경부식도 결손의 재건 : 재건술의 선택 Korean Journal of Head & Neck Oncology (대한두경부종양학회지)
2000 Combination gene therapy using multiple immunomodulatory genes transferred by a defective infectious single-cycle herpes virus in squamous cell cancer Cancer Gene Therapy
1999 양측 예방적 경부곽청술로 확인한 후두 및 하인두 편평세포암종의 잠재전이 Korean Journal of Otolaryngology (대한이비인후과학회지)
1998 영동 세브란스 병원의 후두암 치료 경험 Korean Journal of Otolaryngology (대한이비인후과학회지)
1998 반회신경분지의 단단문합에 의한 개의 후두이식 Journal of the Korean Society of Logopedics and Phoniatrics (대한음성언어의학회지)
1998 갑상선 수술 시의 성대마비의 처치 Korean Journal of Head and Neck Oncology (대한두경부종양학술지)
1998 잠복원발종양의 원발병소 진단시 내시경 유도하 생검 및 구개편도적출의 진단적 의의 Korean Journal of Otolaryngology (대한이비인후과학회지)
1998 상악동에 발생한 비편평세포암의 임상양상 및 치료성적 Korean Journal of Head and Neck Oncology (대한두경부종양학술지)
1997 편측성대마비에 대한 제1형 갑상성형술과 피열연골내전술의 동시수술 효과 Korean Journal of Otolaryngology (대한이비인후과학회지)
1997 양측성대마비의 10년간 경험 분석 Journal of the Korean Society of Logopedics and Phoniatrics (대한음성언어의학회지)
2000 IL-2 및 GM-CSF 유전자를 이입시킨 제한복제성 헤르페스바이러스를 이용한 편평세포암의 유전자치료