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  #루푸스#류마티스관절염#섬유근통증후군#자가면역질환#통풍#퇴행성 관절염#EBS명의#헬스조선명의

학력

경희대학교 의과대학 의학과
경희대학교 대학원 의학과 석사
가톨릭대학교 대학원 의학과 박사

경력

내과 전문의
류마티스내과 분과전문의
핵의학과 전문의
서울대학교병원 핵의학과 전임의
가톨릭의대 강남성모병원 류마티스내과 임상강사
강동경희대학교병원 관절류마티스센터장 역임
강동경희대학교병원 류마티스내과 과장 역임
강동경희대학교병원 류마티스내과 교수(현)

논문

Dysregulated autophagy mediates sarcopenic obesity and its complications via ampk and pgc1α signaling pathways: Potential involvement of gut dysbiosis as a pathological link (International Journal of Molecular Sciences. 2020;21(18):1-21)

Taurine stimulates thermoregulatory genes in brown fat tissue and muscle without an influence on inguinal white fat tissue in a high-fat diet-induced obese mouse model (Foods. 2020;9(6):1-14)

Predicting Imaging Remission in Rheumatoid Arthritis: a Case-control Ultrasound Study (Journal of Korean Medical Science. 2020;35(31):1-9)

A systemic lupus erythematosus patient with thunderclap headache: reversible cerebral vasoconstriction syndrome (Lupus. 2019;28(7):898-902)

Effects of Chronic Intake of a Low Concentration of Taurine on Physical Strength and Body Composition in Mice (Advances in Experimental Medicine and Biology. 2019;1155(11):25-34)

Long-term efficacy, safety and immunogenicity in patients with rheumatoid arthritis continuing on an etanercept biosimilar (LBEC0101) or switching from reference etanercept to LBEC0101: an open-label extension of a phase III multicentre, randomised, double-blind, parallel-group study (ARTHRITIS RESEARCH & THERAPY. 2019;21(1):122-132)

Endocan as a marker of microvascular inflammation in kidney transplant recipients (SCIENTIFIC REPORTS. 2019;9(1):1854-1865)

Anti-obesity effect of taurine through inhibition of adipogenesis in white fat tissue but not in brown fat tissue in a high-fat diet-induced obese mouse model (Amino Acids. 2019;51(2):245-254)

Potential Therapeutic Antibodies Targeting Specific Adiponectin Isoforms in Rheumatoid Arthritis (ARTHRITIS RESEARCH & THERAPY. 2018;20(245):1-12)

An Investigation on the Therapeutic Effect of Thymosin beta 4 and Its Expression Levels in Streptozotocin-Induced Diabetic Mice (BIOMED RESEARCH INTERNATIONAL. 2018;2018(3421568):1-8)

Hypocomplementemic Urticarial Vasculitis Syndrome with Membranous Nephropathy: Case Report (JOURNAL OF KOREAN MEDICAL SCIENCE. 2017;32(12):2064-2068)

Thymosin β4 in rheumatoid arthritis: Friend or foe (BIOMEDICAL REPORTS. 2017;7(0):205-208)

Henoch-Schonlein Purpura With Muscle Involvement, Presenting as Myositis (J clinical Rheumatology. 2017;23(1):60-62)

Complete Remission of Nephrotic Syndrome Without resolution of amyloid deposit after anti-tumor necrosis factor alpha therapy in a patient with ankylosing spondylitis (J Clin Rheumatol. 2016;22(2):86-88)

SAPHO 증후군 환자의 딸에서 발생한 손발바닥고름물집증 (대한류마티스학회지. 2015;22(2):127-131)

Increased expression of endocan in arthritic synovial tissues: Effects of adiponectin on the expression of endocan in fibroblast-like synoviocytes (MOLECULAR MEDICINE REPORTS. 2015;11(4):2695-2702)

The role of adiponectin in the production of IL-6, IL-8, VEGF and MMPs in human endothelial cells and osteoblasts: implications for arthritic joints (EXPERIMENTAL AND MOLECULAR MEDICINE. 2014;46(e72):1-7)

Serum level of osteopontin as an inflammatory marker dose not indicate diseas activity or responsiveness to therapeutic treatments in patients with rheumatoid arthritis (Clin Rheumatol. 2014;33(3):397-402)

Serum adipokine levels in rheumatoid arthritis patients and their contributions to the resistance to treatment (MOLECULAR MEDICINE REPORTS. 2014;9(1):255-260)

Taurine chloramine modulates the expression of adipokines through inhibition of the STAT-3 signaling pathway in differentiated human adipocytes (AMINO ACIDS. 2013;45(6):1415-1422)

A Case of Myotonic Dystrophy with Electrolyte Imbalance (JOURNAL OF KOREAN MEDICAL SCIENCE. 2013;28(7):1111-1113)

Renal involvement in ankylosing spondylitis: prevalence, pathology, response to TNF-a blocker (RHEUMATOLOGY INTERNATIONAL. 2013;33(7):1689-1692)

Serum osteopontin concentration is decreased by exercise-induced fat loss but is not correlated with body fat percentage in obese humans (MOLECULAR MEDICINE REPORTS. 2013;8(2):579-584)

Phosphatidylserine inhibits inflammatory responses in interleukin-1 beta-stimulated fibroblast-like synoviocytes and alleviates carrageenan-induced arthritis in rat (NUTRITION RESEARCH. 2013;33(3):242-250)

Taurine may not alleviate hyperglycemia-mediated endoplasmic reticulum stress in human adipocytes (ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2013;775(1):395-403)

Taurine ameliorates hyperglycemia and dyslipidemia by reducing insulin resistance and leptin level in Otsuka Long-Evans Tokushima fatty (OLETF) rats with long-term diabetes (EXPERIMENTAL AND MOLECULAR MEDICINE. 2012;44(11):665-673)

Synergy between adiponectin and interleukin-1β on the expression of interleukin-6, interleukin-8, and cyclooxygenase-2 in fibroblast-like synoviocytes (EXPERIMENTAL AND MOLECULAR MEDICINE. 2012;44(7):440-447)

Hypoxia differentially affects IL-1-stimulated MMP-1 and MMP-13 expression of fibroblast-like synoviocytes in an HIF-1a-dependent manner (RHEUMATOLOGY. 2012;51(02):443-450)

Implication of MMP-9 and urokinase plasminogen activator (uPA) in the activation of pro-matrix metalloproteinase (MMP)-13 (RHEUMATOLOGY INTERNATIONAL. 2012;32(10):3069-3075)

WIN-34B May Have Analgesic and Anti-Inflammatory Effects by Reducing the Production of Pro-Inflammatory Mediators in Cells via Inhibition of IκB Signaling Pathways (응용약물학회지. 2012;20(1):50-56)

Analgesic and anti-inflammatory effects in animal models of an ethanolic extract of Taheebo, the inner bark of Tabebuia avellanedae (MOLECULAR MEDICINE REPORTS. 2012;6(4):791-796)

Musculoskeletal manifestation in the joints of the diabetic animal model Otsuka Long-Evans Tokushima Fatty rat: A histological study (MOLECULAR MEDICINE REPORTS. 2012;5(3):779-782)

Arthritic disease is more severe in older rats in a kaolin/carrageenan-induced arthritis model (RHEUMATOLOGY INTERNATIONAL. 2012;32(12):3875-3879)

Increased expression of IL-1 receptors in response to IL-1 beta may produce more IL-6, IL-8, VEGF, and PGE(2) in senescent synovial cells induced in vitro than in presenescent cells (RHEUMATOLOGY INTERNATIONAL. 2012;32(7):2005-2010)

Association between serum thymosin beta 4 levels of rheumatoid arthritis patients and disease activity and response to therapy (CLINICAL RHEUMATOLOGY. 2012;31(8):1253-1258)

Effects of the pro-inflammatory milieu on the dedifferentiation of cultured fibroblast-like synoviocytes (MOLECULAR MEDICINE REPORTS. 2012;5(4):1023-1026)

Expression levels and association of gelatinases MMP-2 and MMP-9 and collagenases MMP-1 and MMP-13 with VEGF in synovial fluid of patients with arthritis (RHEUMATOLOGY INTERNATIONAL. 2011;31(4):543-547)

Hypoxia differentially affects IL-1-stimulated MMP-1 and MMP-13 expression of fibroblast-like synoviocytes in an HIF-1a-dependent manner (RHEUMATOLOGY. 2011;0(0):53-60)

Increased levels of thymosin β4 in synovial fluid of patients with rheumatoid arthritis: association of thymosin β4 with other factors that are involved in inflammation and bone erosion in joints (INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES. 2011;14(4):320-324)

Fetal bovine serum requirement for pyrrolidine dithiocarbamate-induced apoptotic cell death of MCF-7 breast tumor cells (European J Pharmacology. 2010;649(1-3):135-139)

Effect of taurine chloramine on the production of matrix metalloproteinase(MMPs) in adiponectin or IL-1 b-stimulated fibroblast-like synoviocytes (J Biomedial Science. 2010;17(supp1):S27-S27)

Differential eVect of IL-1 and TNF- on the production of IL-6, IL-8 and PGE2 in fibroblast-like synoviocytes and THP-1 macropharges (Rheumatol Int. 2010;30(8):1025-1033)

Chronic necrotizing pulmonary aspergillosis in a patient treated with a tumor necrosis factor-a inhibitor (Internation J of Rheumatic diseases. 2010;13(3):e16-e19)

The use of etanercept in a patient with disseminated tuberculosis (RHEUMATOLOGY INTERNATIONAL. 2009;29(0):1377-1380)

Differential effect of IL-1beta and TNF-alpha on the production of IL-6, IL-8 and PGE2 in fibroblast-like synoviocytes and THP-1 macrophages (Rheumatology International. 2009;0(0):0-9)

Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1 beta-stimulated fibroblast-like synoviocytes and in rat arthritis models (ARTHRITIS RESEARCH & THERAPY. 2009;11(2):49-54)

Pyrrolidine dithiocarbamate, a NF-kappa B inhibitor, upregulates MMP-1 and MMP-13 in IL-1 beta-stimulated rheumatoid arthritis fibroblast-like synoviocytes (EUROPEAN JOURNAL OF PHARMACOLOGY. 2009;613(1):167-175)

A case of post-pregnancy osteoporosis combined with ankylosing spondylitis (RHEUMATOLOGY INTERNATIONAL. 2009;29(11):1359-1362)

Mizoribine may suppress bone erosion in patients with rheumatoid arthritis by inhibiting osteoclastogenesis (EUROPEAN JOURNAL OF PHARMACOLOGY. 2009;605(1):46-48)

저서

저서 내용이 없습니다.

보도자료

[여의열전](10) 양형인 강동경희대병원 교수
http://news.khan.co.kr/kh_news/khan_art_view.html?artid=201305091837335&code=900303

온몸이 뻐근하고 아파 잠도 못잘 지경
http://www.mdtoday.co.kr/mdtoday/index.html?no=258706

온몸이 쑤셔 아침에 일어나기도 힘들 정도로 피곤하다
http://www.mdtoday.co.kr/mdtoday/index.html?no=268220

[질환 바로알기-섬유근통증후군] 갱년기 여성의 숨은 복병
http://news.kukinews.com/newsView/kuk201409230016

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