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교수
  #건선#백반증#광선클리닉#아토피피부염

학력

1974~1980 가톨릭대학교 의학 학사
1982~1984 가톨릭대학교 피부과학 석사
1984~1990 가톨릭대학교 피부과학 박사

경력

2012~2013 서울성모병원 임상의학연구소장
2012~2013 의생명산업연구원 연구진흥부원장
2012~2013 성의교정 성의연구진흥실장
2012~2013 성의교정 연구진흥부처장
2012~2012 가톨릭중앙의료원 연구진흥부원장
2012~2013 서울성모병원 연구부원장
2011~2013 서울성모병원 피부과 임상과장
1989~1991 울산해성병원 피부과 피부과장
1985~1989 성모병원 피부과 전강대우
1984~1985 대전성모병원 피부과 전강대우
1981~1984 성모병원 피부과 레지던트
1980~1981 포항성모병원 인턴

논문

2019 Aug
JOURNAL OF DERMATOLOGY 공동저자
Increased risk of psoriasis in subjects with abdominal obesity: A nationwide population-based study

2019 Feb
ANNALS OF DERMATOLOGY 공동저자
Usefulness of the Psoriatic Arthritis Screening and Evaluation Questionnaire to Monitor Disease Activity in Management of Patients with Psoriasis: Findings from the EPI-PSODE Study

2019 Feb
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 교신저자
Liquid chromatography-tandem mass spectrometry of recombinant human extracellular superoxide dismutase (rhSOD3) in mouse plasma and its application to pharmacokinetic study

2018 Dec
ALLERGY 교신저자
Enhanced therapeutic effects of human mesenchymal stem cells transduced with superoxide dismutase 3 in a murine atopic dermatitis-like skin inflammation model

2018 Oct
LIFE SCIENCES 교신저자
Inhibitory effects of extracellular superoxide dismutase on ultraviolet B-induced melanogenesis in murine skin and melanocytes

2018 Jul
BMB REPORTS 교신저자
Superoxide dismutase 3 protects mesenchymal stem cells through enhanced autophagy and regulation of FoxO3a trafficking

2018 Jun
ANTIOXIDANTS & REDOX SIGNALING 공동저자
Extracellular Superoxide Dismutase Attenuates Renal Oxidative Stress Through the Activation of Adenosine Monophosphate-Activated Protein Kinase in Diabetic Nephropathy

2018 Mar
SCIENTIFIC REPORTS 교신저자
Inhibitory effects of superoxide dismutase 3 on Propionibacterium acnes-induced skin inflammation

2017 Oct
KOREAN DERMATOLOGICAL ASSOC 교신저자
Effects of VitabridC12 on Skin Inflammation

2017 Aug
KOREAN DERMATOLOGICAL ASSOC 공동저자
The Clinical Profile of Patients with Psoriasis in Korea: A Nationwide Cross-Sectional Study (EPI-PSODE)

2017 Jun
STEM CELLS 교신저자
Effects of human mesenchymal stem cells co-culture on calcium-induced differentiation of normal human keratinocytes

2017 Jun
Experimental & Molecular Medicine 교신저자
Rhododendrin inhibits toll-like receptor-7-mediated psoriasis-like skin inflammation in mice

2017 Jun
생화학분자생물학회(KOREAN SOCIETY BIOCHEMISTRY & MOLECULAR BIOLOGY) 교신저자
Rhododendrin inhibits toll-like receptor-7-mediated psoriasis-like skin inflammation in mice

2017 Feb
생화학분자생물학회(KOREAN SOCIETY BIOCHEMISTRY & MOLECULAR BIOLOGY) 교신저자
Zinc(II) ion promotes anti-inflammatory effects of rhSOD3 by increasing cellular association

2017 Feb
BMB REPORTS 교신저자
Zinc(II) Ion Promotes Anti-inflammatory Effects of rhSOD3 By Increasing Cellular Association

2017 Jan
STEM CELLS 교신저자
Clinical Trial of Human Umbilical Cord Blood-derived Stem Cells for the Treatment of Moderate-to-Severe Atopic Dermatitis: Phase I/IIa Studies

2016 Aug
EXPERIMENTAL DERMATOLOGY 교신저자
Extracellular superoxide dismutase ameliorates house dust mite-induced atopic dermatitis-like skin inflammation and inhibits mast cell activation in mice

2016 Jul
BMC DERMATOLOGY 공동저자
A multicenter, randomized, open-label pilot trial assessing the efficacy and safety of etanercept 50 mg twice weekly followed by etanercept 25 mg twice weekly, the combination of etanercept 25 mg twice weekly and acitretin, and acitretin alone in patients with moderate to severe psoriasis

2016 Mar
PROTEIN EXPRESSION AND PURIFICATION 교신저자
Expression, subcellular localization, and enzyme activity of a recombinant human extra-cellular superoxide dismutase in tobacco (Nicotiana benthamiana L.)

2016 Mar
MOLECULES AND CELLS 교신저자
Cloning, Purification, and Characterization of Recombinant Human Extracellular Superoxide Dismutase in SF9 Insect Cells

2016 Feb
ANTIOXIDANTS & REDOX SIGNALING 교신저자
Effects of human mesenchymal stem cells transduced with superoxide dismutase on imiquimod-induced psoriasis-like skin inflammation in mice

2015 Oct
ANTIOXIDANTS & REDOX SIGNALING 교신저자
SOD3 variant R213G altered SOD3 function, leading to ROS mediated inflammation and damage in multiple organs of premature aging mice

2015 Aug
JOURNAL OF INVESTIGATIVE DERMATOLOGY 교신저자
Capsiate Inhibits DNFB-Induced Atopic Dermatitis in NC/Nga Mice through Mast Cell and CD4+T-Cell Inactivation

2015 Aug
BRITISH JOURNAL OF PHARMACOLOGY 교신저자
Imidazole-based alkaloid derivative LCB54-0009 suppresses ocular angiogenesis and lymphangiogenesis in models of experimental retinopathy and corneal neovascularization

2015 Jul
대한피부과학회지 교신저자
잘룩창자암 환자에서 항암치료 후 악화된파종얕은광선땀구멍각화증 1예

2015 Jul
EXPERIMENTAL DERMATOLOGY 교신저자
Anti-angiogenic activity of thienopyridine derivative LCB03-0110 by targeting VEGFR-2 and JAK/STAT3 Signalling

2015 Feb
BMB REPORTS 교신저자
Enhancement of potency and stability of human extracellular superoxide dismutase

2014 Dec
대한피부과학회지 교신저자
Dermatofibroma on the Lip

2014 Dec
ANNALS OF DERMATOLOGY (08년3월이후) 교신저자
A Case of Psoriasis Exacerbated by Radioactive Iodine Therapy

2014 Oct
AMERICAN JOURNAL OF DERMATOPATHOLOGY 공동저자
Expression of Insulin-like Growth Factor-1 Receptor in Conventional Cutaneous Squamous Cell Carcinoma With Different Histological Grades of Differentiation.

2014 Oct
ANNALS OF DERMATOLOGY (08년3월이후) 교신저자
A Suspected Case and Literature Review of McCune-Albright Syndrome

2014 Aug
대한피부과학회지 교신저자
물집유사천포창이 동반된 수포성 옴 1예

2014 Jul
대한피부과학회지 교신저자
건선 환자에서 Infliximab (Remicadeⓡ) 투여 후발생한 신기능 저하 1예

2014 Apr
JOURNAL OF DERMATOLOGY 교신저자
Case of rudimentary meningocele in identical twin sisters

2014 Apr
ALLERGY 교신저자
Homoisoflavanone prevents mast cell activation and allergic responses by inhibition of Syk signaling pathway

2014 Mar
EXPERIMENTAL AND MOLECULAR MEDICINE 교신저자
Anti-inflammatory activity of compounds isolated from Astragalus sinicus L. in cytokine-induced keratinocytes and skin

2013 Dec
ARCHIVES OF DERMATOLOGICAL RESEARCH 교신저자
DNA methylation analysis of CD4+ T cells in patients with psoriasis.

2013 Dec
JOURNAL OF INVESTIGATIVE DERMATOLOGY 교신저자
Phytosphingosine Derivatives Ameliorate Skin Inflammation by Inhibiting NF-κB and JAK/STAT Signaling in Keratincoytes and Mice.

2013 Nov
EUROPEAN JOURNAL OF PHARMACOLOGY 교신저자
Novel isonahocol E3 exhibits anti-inflammatory and anti-angiogenic effects in endothelin-1-stimulated human keratinocytes

2013 Nov
(교수업적평가) 보직교수 논문인정 교신저자
Extracellular Superoxide Dismutase (SOD3) for the Treatment of Inflammatory Skin Diseases

2013 Aug
BMB REPORTS 교신저자
Human extracellular superoxide dismutase (EC-SOD) expression in transgenic chicken

2013 Aug
EUROPEAN JOURNAL OF PHARMACOLOGY 교신저자
Rhododendrin ameliorates skin inflammation through inhibition of NF-kappa B, MAPK, and PI3K/Akt signaling

2013 Apr
BIOCHEMICAL PHARMACOLOGY 교신저자
Kurarinone regulates immune responses through regulation of the JAK/STAT and TCR-mediated signaling pathways

2013 Apr
JOURNAL OF COSMETIC AND LASER THERAPY 공동저자
A Split-face comparison of ablative fractional lasers (CO2 and Er:YAG) in Asian patients; postprocedure erythema, pain and patient's satisfaction

2013 Mar
JOURNAL OF INVESTIGATIVE DERMATOLOGY 교신저자
Loss of Extracellular Superoxide Dismutase Induces Severe IL-23-Mediated Skin Inflammation in Mice

2012 Dec
BMB REPORTS 교신저자
IFNγ-mediated inhibition of cell proliferation through increased PKCδ-induced overexpression of EC-SOD

2012 Nov
ANTIOXIDANTS & REDOX SIGNALING 교신저자
Superoxide Dismutase 3 Controls Adaptive Immune Responses and Contributes to the Inhibition of Ovalbumin-Induced Allergic Airway Inflammation in Mice

2012 Oct
PHYTOTHERAPY RESEARCH 교신저자
Pachastrissamine from Pachastrissa sp. Inhibits Melanoma Cell Growth by Dual Inhibition of Cdk2 and ERK-mediated FOXO3 Downregulation.

2012 Aug
JOURNAL OF DERMATOLOGICAL SCIENCE 교신저자
Role of superoxide dismutase 3 in skin inflammation

2012 May
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 교신저자
The characteristics of genome-wide DNA methylation in naive CD4+ T cells of patients with psoriasis or atopic dermatitis

2012 Apr
JOURNAL OF INVESTIGATIVE DERMATOLOGY 교신저자
Overexpression of Cathepsin S Induces Chronic Atopic Dermatitis in Mice

2012 Feb
JOURNAL OF DERMATOLOGICAL SCIENCE 교신저자
EC-SOD induces apoptosis through COX-2 and galectin-7 in the epidermis

2012 Feb
ANTIOXIDANTS & REDOX SIGNALING 교신저자
Superoxide Dismutase 3 Suppresses Hyaluronic Acid Fragments Mediated Skin Inflammation by Inhibition of Toll-Like Receptor 4 Signaling Pathway: Superoxide Dismutase 3 Inhibits Reactive Oxygen Species-Induced Trafficking of Toll-Like Receptor 4 to Lipid Rafts

2011 Dec
Free Radical Biology and Medicine 교신저자
Regulation of skin inflammation and angiogenesis by EC-SOD via HIF-1α and NF-κB pathways.

2011 Oct
ANNALS OF DERMATOLOGY (08년3월이후) 교신저자
Primary Granulocytic Sarcoma of the Face

2011 Sep
JOURNAL OF DERMATOLOGICAL SCIENCE 공동저자
Efficacy and safety of ustekinumab for the treatment of moderate-to-severe psoriasis: A phase III, randomized, placebo-controlled trial in Taiwanese and Korean patients (PEARL)

2011 Aug
JOURNAL OF INVESTIGATIVE DERMATOLOGY 교신저자
N-(3,5-Dimethylphenyl)-3-Methoxybenzamide (A(3)B(5)) Targets TRP-2 and Inhibits Melanogenesis and Melanoma Growth

2011 Jul
JOURNAL OF INVESTIGATIVE DERMATOLOGY 공동저자
Transduced PEP-1-FK506BP ameliorates atopic dermatitis in NC/Nga mice

2011 Jun
FEBS LETTERS 공동저자
Identification of Drosophila SOD3 and its protective role against phototoxic damage to cells

2011 May
EXPERIMENTAL AND MOLECULAR MEDICINE 공동저자
Benzoxathiol derivative BOT-4-one suppresses L540 lymphoma cell survival and proliferation via inhibition of JAK3/STAT3 signaling

2011 Feb
ARCHIVES OF PHARMACAL RESEARCH 공동저자
In vitro sortase A inhibitory and antimicrobial activity of flavonoids isolated from the roots of Sophora flavescens

2011 Jan
대한피부과학회지 교신저자
갑상샘전절제술 후 Levothyroxine Sodium을 복용하고 있는 환자에서 발생한 Cronkhite-Canada 증후군

2011 Jan
BMB REPORTS 교신저자
Inactive extracellular superoxide dismutase disrupts secretion and function of active extracellular superoxide dismutase

2010 Nov
BRITISH JOURNAL OF DERMATOLOGY 공동저자
The antimicrobial peptide human cationic antimicrobial protein-18/cathelicidin LL-37 as a putative growth factor for malignant melanoma

2010 Nov
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 공동저자
Expression, High Cell Density Culture and Purification of Recombinant EC-SOD in Escherichia coli

2010 Sep
JOURNAL OF DERMATOLOGICAL SCIENCE 교신저자
Homoisoflavanone inhibits UVB-induced skin inflammation through reduced cyclooxygenase-2 expression and NF-kappa B nuclear localization

2010 Aug
BIOORGANIC & MEDICINAL CHEMISTRY 공동저자
Identification of a potent and noncytotoxic inhibitor of melanin production

2010 May
FREE RADICAL BIOLOGY AND MEDICINE 교신저자
Capsiate inhibits ultraviolet B-induced skin inflammation by inhibiting Src family kinases and epidermal growth factor receptor signaling

2009 Nov
HUMAN MOLECULAR GENETICS 공동저자
Overexpression of Hr links excessive induction of Wnt signaling to Marie Unna hereditary hypotrichosis

2009 Oct
JOURNAL OF BIOLOGICAL CHEMISTRY 공동저자
SYNDECAN-2 REGULATES THE MIGRATORY POTENTIAL OF MELANOMA CELLS

2009 Sep
GENOME BIOLOGY 공동저자
Nucleosome deposition and DNA methylation at coding region boundaries

2009 Sep
소아알레르기 호흡기학회지 교신저자
아토피피부염 치료의 최신경향

2009 Jul
월간 클리닉저널 교신저자
건선의 생물학적 제제 치료

2009 May
ANNALS OF DERMATOLOGY (08년3월이후) 교신저자
A Case of Inflammatory Disseminated Superficial Porokeratosis in a Colon Cancer Patient

2009 Feb
JOURNAL OF DERMATOLOGICAL SCIENCE 교신저자
Differential expression of prohibitin and regulation of apoptosis in wild-type and COX-2 null mouse embryonic fibroblasts

2008 Dec
CELL TRANSPLANTATION 공동저자
The therapeutic effect of extracellular superoxide dismutase mouse embryonic fibroblast on collagen-induced arthritis mice

2008 Dec
ANNALS OF DERMATOLOGY (08년3월이후) 교신저자
Developmant of Halo Navus Around Nevus Spilus as a Central Nevus, and the Concurrent Vitiligo

2008 Oct
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY 교신저자
Increased yield of high-purity and active tetrameric recombinant human EC-SOD by solid phase refolding.

2008 Sep
FEBS LETTERS 교신저자
Reciprocal regulation of 12- and 15-lipoxygenases by UV-irradiation in human keratinocytes.

2008 Aug
BMB REPORTS 공동저자
Comparative proteomic analysis of peripheral blood mononuclear cells from atopic dermatitis patients and healthy donors

2008 Jun
BIOORGANIC & MEDICINAL CHEMISTRY 공동저자
Monoglycerides from the brown alga Sargassum sagamianum: Isolation, synthesis, and biological activity.

2008 Mar
대한피부과학회지 교신저자
Recurrent Classical Type of Kaposi's Sarcoma Treated by Interferon-α

2008 Mar
EUROPEAN JOURNAL OF PHARMACOLOGY 교신저자
Sargaquinoic acid and Sargachromenol, extracts of Sagassum sagamianum, induce apoptosis in HaCaT cells and mice skin: its potentiation of UVB-induced apoptosis

2008 Feb
대한피부과학회지 교신저자
고립성 아교종 1예

2008 Jan
CANCER RESEARCH 공동저자
Capsiate a nonpungent capsaicin-like compound, inhibits angiogenesis and vascular permeability via a direct inhibition of Src kinase activity

2007 Nov
JOURNAL OF DERMATOLOGICAL SCIENCE 교신저자
Associations of IL-2 and IL-4 gene polymorphisms with psoriasis in the Korean population

2007 Oct
FEBS LETTERS 교신저자
Wondonin, a novel compound, inhibits hypoxia-induced angiogenesis through Hypoxia-Inducible Factor 1 alpha

2007 Aug
JOURNAL OF INVESTIGATIVE DERMATOLOGY 교신저자
EC-SOD suppresses contact hypersensitivity in mouse skin by impairing Langerhans cell migration

2007 Aug
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 교신저자
Altered expressin of prohibitin in psoriatic lesions and its molecular and cellular implication

2007 Jul
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 교신저자
Improvement of Atopic dermatitis in NC/Nga mice by topical application of CpG phosphodiestr-ODN

2007 Jul
STEM CELLS 공동저자
A novel function of interleukin-10 promoting self-renewal of hematopoietic stem cells

2007 Jul
JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY 교신저자
Effect of Dendritic Cells Treated with CpG-ODN on Atopic Dermatitis of Nc/Nga mice

2007 May
FREE RADICAL RESEARCH 교신저자
[6]-Gingerol prevents UVB-induced ROS production and COX-2 expression in vitoro and in vivo

2007 May
JOURNAL OF INVESTIGATIVE DERMATOLOGY 교신저자
IFN-r Upregulates Expression of the Mouse Complement C1rA Gene in Keratinocytes via IFN-Regulatory Factor-1

2007 Mar
JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY 공동저자
Transduced PEP-1-Grb7 Fusion Protein Suppressed LPS-induced COX-2 Expression

2007 Mar
JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY 공동저자
Expression of AGR-2 in Chicken Oviduct during Laying Period

2007 Jan
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 교신저자
Insulin-like growth factor-II regulates the 12-lipoxygenase gene expression and promotes cell proliferation in human keratinocytes via the extracellular regulatory kinase and phosphatidylinositol 3-kinase pathways.

2007 Jan
JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY 교신저자
IL-4 Suppresses UVB-induced Apoptosis in Skin

저서

2016 Sep
NOVA BIOMEDICAL 공동
SUPEROXIDE DISMUTASE(SOD) SOURCES,THERAPEUTIC USES AND HEALTH BENEFITS

2011 Mar
군자출판사 공동
임상진료지침 Current principles and clinical practice of dermatology

2008 Feb
대한피부과학회 교과서 편찬위원회 공동
피부과학 제5판

2006 Nov
도서출판 신일상사 공동
건선에 대한 100문 100답

2006 Oct
도서출판 대영 공동
안면노화방지 로드맵 (Advanced Cosmetic Dermatology 2)

2006 Sep
MECCA 공동
건선의 병인과 치료 Update in Psoriaisi 건선

2001 Jul
여문각 공동
아토피피부염의진단과치료

2001 Jan
여문각 공동
피부과학(피부면역학)

2001 Jan
군자출판사 공동
대한 천식 및 알레르기학 교과서

2000 Dec
의학문학사 공동
응급의학(소아피부질환)

2017 Oct
군자출판사(주) 공동
아토피피부염

보도자료

[헬스캡슐]108개 전문병원 정보 담은 ‘전문병원 가이드북’ 출시 外
http://news.donga.com/3/all/20181113/92851010/1

난치질환 아토피 피부염, 줄기세포로 치료길 열었다
http://news.joins.com/article/20145317

‘중증 아토피’ 줄기세포로 치료 길 열려
http://news.donga.com/3/all/20160609/78565696/1

포스팅

포스팅 내용이 없습니다.

영상자료

중증 아토피, 줄기세포로 치료 가능성 첫 확인
http://science.ytn.co.kr/program/program_view.php?s_mcd=0082&s_hcd=&key=201606091057316798

"줄기세포로 아토피 치료" 국내 연구진, 임상시험 성공
http://news.jtbc.joins.com/article/article.aspx?news_id=NB11249649

약 안 듣던 '아토피'…줄기세포로 치료 도전
https://news.sbs.co.kr/news/endPage.do?news_id=N1003615942&plink=SEARCH&cooper=SBSNEWSSEARCH

발표자료

1. 피부의 대표적 만성 염증성 질환들인 아토피피부염과 건선에 대한 기초연구
2. 아토피부염과 건선의 치료를 위한 새로운 개념의 치료제 개발