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  #베체트병#구강점막질환

학력

연세대학교 의학과 박사(1985)
연세대학교 의학과 석사(1982)
연세대학교 의학과 학사(1976)

경력

2007.3-2010.7 세브란스병원 제1진료부원장
2005.3-2007.2 세브란스병원 적정진료관리실장
2005.3-2005.12 의료협력센터 소장
2002-2005 의과대학 교무부장
1998.3- 연세대학교 의과대학 피부과학교실 교수
1996-2002 연세대학교 의과대학 피부과학교실 주임교수
1996-2000 연세대학교 의과대학 임상의학연구센터 형태학 연구실장
1995-1996 세브란스병원 교육수련부 차장
1987-1990 연세대학교 원주의과대학 피부과학교실 주임교수
1985-1986 일본 가와사끼의대 및 쥰텐토의대

논문

한국지혈혈전학회지 7 1:25~34,2000
Multinucleate cell angiohistiocytoma 1예.
대한피부과학회지 38 7:983~985,2000
The effect of herpesvirus infection on the expression of cell adhesion molecules on cultured human dermal microvascular endothelial cells.
JOURNAL OF DERMATOLOGICAL SCIENCE 24 1:38~47,2000
제 V형 과지질 단백혈증을 동반한 발진성 황색종 1예.
대한피부과학회지 39 6:693~695,2001
Clinical spectrum of Behcet’s Disease.
JOURNAL OF DERMATOLOGY 28 11:610~613,2001
Colonoscopic findings in intestinal Behcet's disease
INFLAMMATORY BOWEL DISEASES 7:243~249,2001
Combined treatment of colchicine and herbal medicines(Gamichunghyulbohyul-tang or Gamiyongdamsagan-tang) attenuate the Behcet’s disease symptoms in mi
J Korean Oriental Med 22 2:102~108,2001
Epidemiologic and clinical survey of Behcet’s disease in Korea: the first multicenter study
JOURNAL OF KOREAN MEDICAL SCIENCE 16 0:615~618,2001
Experimental studies on the antiviral agent famciclovir in Behc;et's disease symptoms in ICR mice.
BRITISH JOURNAL OF DERMATOLOGY 145 0:799~804,2001
Expression of Th2 cytokine decreases the development of and improves Behcet’s disease-like symptoms induced by Herpes Simplex Virus in mice.
The Journal of Infectious Disease 183 0:1180~1186,2001
Treatment of Bowen‘s disease with a specially designed radioactive skin patch.
STATE LEGISLATURES 27 0:842~846,2001
Activation of extracellular signal regulated kinase 1/2 in human dermal microvascular endothelial cells stimulated by antiendothelial cell antibodies
JOURNAL OF DERMATOLOGICAL SCIENCE 30 0:63~72,2002
Clear cell papulosis: an immunohistochemical study to determine histogenesis.
JOURNAL OF CUTANEOUS PATHOLOGY 29 0:11~14,2002
베체트병 환자에서 말초혈액 단핵세포의 Streptococcus sanguis 항원에 대한 사이토카인 생성.
대한피부연구학회지(Korean Journal of InvestigativeDermatology) 9 4:183~190,2002
입술에 발생한 palisaded encapsulated neuroma 1예.
대한피부과학회지 40 12:1552~1556,2002
모발로 분화하는 종양에 대한 임상 및 병리조직학적 소견
대한피부과학회지 41 9:1177~1186,2003
색소성 피부질환에 대한 큐스위치 알렉산드라이트 레이저 치료직후의 조직, 면역조직화학, 전자현미경적 소견.
대한피부과학회지 41 8:1014~1021,2003
Behcet's disease: The first Mongolian case in literature showing HLA B51, MICA gene type *5/*6.
YONSEI MEDICAL JOURNAL 44 5:935~938,2003
Clinical features of patients with Behcet's disease and epididymitis.
JOURNAL OF UROLOGY 170 0:1177~1186,2003
Human α-enolase from endothelial cells as a target antigen of anti-endothelial cell antibody in Behcet's disease.
ARTHRITIS AND RHEUMATISM 48 7:2025~2035,2003
Influence of sex on patients with Behcet's disease in Korea.
JOURNAL OF KOREAN MEDICAL SCIENCE 18 0:231~235,2003
Intercellular adhesion molecule-1 polymorphisms in Korean patients with Behcet's disease.
JOURNAL OF KOREAN MEDICAL SCIENCE 18 3:415~418,2003
베체트병(Behcet';s disease) 환자에서 항핵항체(Antinuclear antibody)의 발현에 관한 연구
대한피부과학회지(Korean Journal Of Dermatology) 42 5:545~550,2004
상안검에 발생한 Palisaded Encapsulated Neuroma 1예
대한피부과학회지(Korean Journal Of Dermatology) 42 12:1603~1605,2004
특발성 범발성 피부석회증 1예
대한피부과학회지(Korean Journal Of Dermatology) 42 10:1313~1316,2004
Proteomic analysis of the proteins expressed by hydrogen peroxide treated cultured human dermal microvascular endothelial cells
PROTEOMICS 5 6:1507~1519,2005
Coexistence of Behcet’s disease and autoimmune disease: Clinical features of 11 cases
JOURNAL OF DERMATOLOGY 32 7:614~616,2005
Association of HYPA haplotype in the mannose-binding lectin gene-2 with Behcet’s disease
TISSUE ANTIGENS 65:260~265,2005
Cutaneous metastasis of choriocarcinoma: A case report
JOURNAL OF KOREAN MEDICAL SCIENCE 20 4:683~686,2005
포진성 모낭염 1예
Korean Journal Of Dermatology 43 2:287~290,2005
베체트병과 동반된 IgA 신병증 1예
대한내과학회지(korean Journal of medcine) 68 3:329~333,2005
Behcet's disease combined with various types of fistula
YONSEI MEDICAL JOURNAL 46 5:625~628,2005
베체트병 환자에서 혈청 항 인체 α-enolase 항체의 Streptococcus sanguis에 대한 교차반응
대한피부연구학회지(Korean Journal of InvestigativeDermatology) 12 4:83~92,2005
Searching for aging-related proteins in human dermal microvascular endothelial cells treated with anti-aging agents
PROTEOMICS 6 4:1351~1361,2006
Association of TNFA promoter region haplotype in Behcet’s disease
JOURNAL OF KOREAN MEDICAL SCIENCE 21:596~601,2006
유전분 침착이 동반된 파종상 표재성 한공각화증 1예
대한피부과학회지 44 8:1018~1020,2006
Fibrolamellar nerve sheath tumor or sclerotic neurofibroma? [3]
JOURNAL OF CUTANEOUS PATHOLOGY 33:760~761,2006
HLA-E*0101 and HLA-G*010101 reduce the risk of Behcet’s disease
TISSUE ANTIGENS 69 2:139~144,2007
Using proteomics to identify targets of antiendothelial cell antibodies
EXPERT IN REVIEW OF CLINICAL IMMUNOLOGY 3 6:983~991,2007
골수이형성 증후군 환자에서 발생한 조직구양 Sweet 증후군 1예
대한피부과학회지(Korean Journal Of Dermatology) 45 7:754~757,2007
구강편평태선 35예의 임상적 고찰
대한피부과학회지(Korean Journal Of Dermatology) 45 1:1~8,2007
The effect of wet-wrap dressing on epidermal barrier in patients with atopic dermatitis
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 21:1360~1368,2007
Using pCIN-mIL-4 DNA vector to express mRNA and protein and to improve herpes simplex virus-induced Behcet';s disease symptoms in mice
VACCINE 25:7047~7055,2007
Association of CD94/NKG2A, CD94/NKG2C, and its ligand HLA-E polymorphisms with Behcet’s disease
TISSUE ANTIGENS 70:307~313,2007
Leg ulcers in Behcet's disease[5]
British Journal Of Dermatology 158:178~179,2008
Increased expression of interleukin-23 p19 mRNA in erythema nodosum-like lesions of Behcet's disease
British Journal Of Dermatology 158:505~511,2008
Dermatological features in Behcet's disease-associated vena cava obstruction
British Journal Of Dermatology 159:555~560,2008
Two cases of acute leukopenia induced by colchicine with concurrent immunosuppressants use in Behcet`s disease
Yonsei Medical Journal 49 1:171~173,2008
베체트병에서 MIF 발현에 대한 연구
대한피부과학회지 46 5:611~618,2008
Clinical manifestations associated with high titer of anti-streptolysin O in Behcet’s disease
Clinical Rheumatology 27 8:999~1003,2008
Tumor necrosis factor alpha small interfering RNA decreases herpes simplex virus-induced inflammation in a mouse model
Journal Of Dermatological Science 52:87~97,2008
The efficacy of topical 0.2% hyaluronic acid gel on recurrent oral ulcers: comparison between recurrent aphthous ulcers and the oral ulcers of Behcet`s disease
Journal Of The European Academy Of Dermatology And Venereology 22:590~595,2008
지도모양혀 55예의 임상적 고찰
대한피부과학회지 46 9:1171~1178,2008
EULAR recommendations for the management of Behcet’s disease
Annals Of The Rheumatic Diseases 67 12:1656~1662,2008
Rebamipide affects the efficiency of colchicine for the herpes simplex virus-induced inflammation in a Behcet's disease mouse model
European Journal Of Pharmacology 598 1-3:112~117,2008
베체트병에서 뼈신티그래피를 통한 관절 침범의 평가
대한피부과학회지 47 1:30~35,2009
Sudden Visual Loss Due to Occlusive Venous Vasculitis Associated With Sweet Syndrome
Archives Of Dermatology 145 2:216~218,2009
Bart 증후군 1예
대한피부과학회지 47 4:463~467,2009
Behcet's disease: remission of patient symptoms after oral contraceptive therapy
Clinical And Experimental Dermatology 34 5:e88~e90,2009
만성 구강 궤양을 동반한 건선 1예
대한피부과학회지 47 5:580~582,2009
Comparison of the clinical features of recurrent aphthous stomatitis and Behcet's disease
Clinical And Experimental Dermatology 34:e208~e212,2009
Human anti-α-enolase antibody in sera from patients with Behcet's disease and rheumatologic disorders
Clinical And Experimental Rheumatology 27 53:63~66,2009
CTLA4 gene polymorphisms and soluble CTLA4 protein in Behcet's disease
Tissue Antigens 74 3:222~227,2009
Management of Behcet disease: a systematic literature review for the European League Against Rheumatism evidence-based recommendations for the management of Behcet disease
Annals Of The Rheumatic Diseases 68 10:1528~1534,2009
Use of 532-nm Q-switched Nd:YAG laser for smoker's gingival hyperpigmentation
Journal Of Cosmetic And Laser Therapy : Official Publication Of The European Society For Laser Dermatology 12 2:77~80,2010
Efficacy and safety of 1064-nm Q-switched Nd:YAG laser with low fluence for keloids and hypertrophic scars
Journal Of The European Academy Of Dermatology And Venereology 24:1070~1074,2010
Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behcet's disease
Nature Genetics 42 8:698~702,2010
identification of streptococcal proteins reacting with sera from Behcet's disease and rheumatic disorders
Clinical And Experimental Rheumatology 28 4:s31~s38,2010
Spitz naevus is rare in Korea
CLINICAL AND EXPERIMENTAL DERMATOLOGY 35 2:135~139,2010
Treatment of Striae Distensae Using an Ablative 10,600-nm Carbon Dioxide Fractional Laser: A Retrospective Review of 27 Participants
Dermatologic Surgery 36 11:1683~1690,2010
Lower-Fluence, Higher-Density versus Higher-Fluence, Lower-Density Treatment with a 10,600-nm Carbon Dioxide Fractional Laser System: A Split-Face, Evaluator-Blinded Study
Dermatologic Surgery 36 12:2022~2029,2010
신종인플루엔자 대비 모의훈련 진행 경험
병원감염관리 15 2:103~111,2010
Ultrastructural features of lipoatrophia semicircularis in Behcet's disease
Clinical And Experimental Rheumatology 28 4 suppl 60:S97~S98,2010
Visualisation of the inflammatory process in Behcet's disease using fluorodeoxyglucose positron emission tomography: a case report
Clinical And Experimental Rheumatology 28 4 9suppl 60):S92~S93,2010
Major arterial aneurysms and pseudoaneurysms in Behcet's disease: results from a single centre
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY 40 1:64~67,2011
Detection of Cardiovascular System Involvement in Behcet's Disease Using Fluorodeoxyglucose Positron Emission Tomography
SEMINARS IN ARTHRITIS AND RHEUMATISM 40 5:461~466,2011
Synthesized pyridine compound derivatives decreased TNF alpha and adhesion molecules and ameliorated HSV-induced inflammation in a mouse model
European Journal of Pharmacology 657 1-3:167~172,2011
Detection of Tuberculous Lymphadenopathy by Positron Emission Tomography/Computed Tomo-graphy in a Patient with Behcet's Disease
ACTA DERMATO-VENEREOLOGICA 91 4:470~471,2011
Expression of Pro-inflammatory Protein S100A12 (EN-RAGE) in Behcet's Disease and Its Association with Disease Activity: A Pilot Study
ANNALS OF DERMATOLOGY 23 3:313~320,2011
Erythema nodosum-like skin lesions associated with Behcet’s disease show 18F-fluorodeoxyglucose uptake on PET/CT
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 29 4:S-91~S92,2011
Increased retinol-binding protein (RBP) 4 and anti-RBP4 antibody in alopecia areata
BRITISH JOURNAL OF DERMATOLOGY 165:837~844,2011
CD4+ CD25+ regulatory T cells ameliorate Behcet’s disease-like symptoms in a mouse model
CYTOTHERAPY 13 7:835~847,2011
Identification of HnRNP-A2/B1 as a Target Antigen of Anti-Endothelial Cell IgA Antibody in Behcet's Disease
JOURNAL OF INVESTIGATIVE DERMATOLOGY 132 3:601~608,2012
New insights in the clinical understanding of Behcet's disease
YONSEI MEDICAL JOURNAL 53 1:35~42,2012
Ultrastructural features of nevus comedonicus
International Journal of Dermatology 51 5:626~628,2012
Unilateral Nevoid Telangiectasia Associated with Ipsilateral Melorheostosis
ANNALS OF DERMATOLOGY 24 2:206~208,2012
Anti-cyclic citrullinated peptide antibodies and joint involvement in Behcet's disease
YONSEI MEDICAL JOURNAL 53 4:759~764,2012
Learning from HSV-infected mice as a model of Behcet's disease
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 30 Suppl.72:s96~s103,2012
Matrix metalloprotenase-2,-9,-12, and tissue inhibitor of metalloproteinase 2 gene polymorphisms and cutaneous expressions in patients with Behcet’s disease.
TISSUE ANTIGENS 79 5:333~339,2012
Behcet's disease in concurrence with psoriasis
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 27 1:e113~e118,2013
Renal manifestations in 2007 Korean patients with Behcet's disease
YONSEI MEDICAL JOURNAL 54 1:189~196,2013
Streptococcus sanguinis and the sera of patients with Behcet's disease stimulate membrane expression of α-enolase in human dermal microvascular endothelial cells
ARCHIVES OF DERMATOLOGICAL RESEARCH 305 3:223~232,2013
Serum IgA reactivity against GroEL of Streptococcus sanguinis and human heterogeneous nuclear ribonucleoprotein A2/B1 in patients with Behcet disease
BRITISH JOURNAL OF DERMATOLOGY 168 5:977~983,2013
Both the sera of patients with Behcet's disease and Streptococcus sanguis stimulate membrane expression of hnRNP A2/B1 in endothelial cells
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY 42 3:241~246,2013
Differential expression of monocyte/macrophage markers between active and inactive stage of patients with Behcet’s disease
Pathology Discovery - -:1~11,2013
Detection of the inflammatory process in a Behcet’s disease-like mouse model using 18F-fluorodeoxyglucose positron emission tomography
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 31 Suppl.77:S47~S53,2013
Immunopathogenic Role of Herpes Simplex Virus in Behcet’s Disease
Genetics Research International 2013 Article ID 638273:1~6,2013
Immunopathogenic characterization of cutaneous inflammation in Behcet's disease
Journal of the European Academy of Dermatology and Venereology 28 1:51~57,2014
Changing clinical expression of Behcet's disease in Korea during three decades(1983-2012):chronological analysis of 3674 hospital based patients
BRITISH JOURNAL OF DERMATOLOGY 170 2:458~461,2014

저서

Behcet's disease; A guide to its clinical understanding. Springer Verlag. Mar., 2001

보도자료

입이 자주 헐고 피곤하다면 '베체트병' 의심해봐야
http://medipana.com/news/news_viewer.asp?NewsNum=164472&MainKind=A&NewsKind=5&vCount=12&vKind=1

입안이 따끔 자꾸 입안 헐면 베체트병 의심
https://www.mk.co.kr/news/it/view/2015/03/255512/

[건강 일문일답] 구내염에 소금물 가글 괜찮을까?
http://www.k-health.com/news/articleView.html?idxno=52151

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[KBS 생로병사의 비밀] 피부가 보내는 구조신호
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