이현주

  #소아감염성질환#발열#결핵#예방접종

학력

2002 이화여자대학교 의과대학 의학과 졸업
2007 이화여자대학교 의과대학 의학과 석사
2010 이화여자대학교 의과대학 의학과 박사

경력

2003-2007 이화여자대학교 목동병원 소아청소년과 전공의
2007-2009 이화의료원 소아청소년과 전임의
2009-2011 이화의료원 소아청소년과 임상조교수
2010-2011 이화여자대학교 의과학연구소 연구교수
2012-2016 분당서울대학교병원 소아청소년과 조교수
2016-현재 분당서울대학교병원 소아청소년과 부교수

논문

폐구균 단백결합 백신의 백신관련 혈청형에 대한 소아에서의 면역 반응에 대해 최초 보고 Lee H, Nahm MH, Burton R, Kim KH, “ Immune response in infants of the heptavalent pneumococcal conjugate vaccine against vaccine-related serotypes 6A and 19A”, Clin Vaccine Immunol. 16(3):376-81, 2009

1. Kim NH, Lee J, Lee SJ, Lee H, Kim KH, Park SE, Lee HJ, “Immunogenicity and safety of pneumococcal 7-valent conjugate vaccine (diphtheria CRM(197) protein conjugate; Prevenar ) in Korean infants: differences that are found in Asian children”, Vaccine 2007:25(45):7858-65

2. Kim KH, Lee H, Chung EH, Kang JH, Kim JH, Kim JS, Lee HJ, Oh SH, Park EA, Park SE, “Immunogenicity and Safety of Two Different Haemophilus influenzae type b Conjugate Vaccines in Korean Infants”, J Korean Med Sci. 2008:23(6):929-36.

3. Lee H, Nahm MH, Burton R, Kim KH, “ Immune response in infants to the heptavalent pneumococcal conjugate vaccine against vaccine-related serotypes 6A and 19A”, Clin Vaccine Immunol. 2009:16(3):376-81.

4. Lee H, Hahn S, Lee HJ, Kim KH, “Immunogenicity of Haemophilus influenzae type b Conjugate Vaccines in Korean Infants: a Meta-analysis”, J Korean Med Sci. 2010:25(1):90-6.

5. Lee H, Nahm MH, Kim KH, “The effect of age on the response to the pneumococcal polysaccharide vaccine”, BMC Infect Dis. 2010:10:60.

6. Cho HK, Lee H, Kang JH, Kim KN, Kim DS, Kim YK, Kim JS, Kim JH, Kim CH, Kim HM, Park SE, Oh SH, Chung EH, Cha SH, Choi YY, Hur JK, Hong YJ, Lee HJ, Kim KH, “ The causative organisms of bacterial meningitis in Korean children in 1996-2005”, J Korean Med Sci. 2010:25(6):895-9.

7. Lee H, Kim HW, Cho HK, Park EA, Choi KM, Kim KH, “ Reappraisal of MMR Vaccines Currently Used in Korea”, Pediatr Int., 2011:53(3):374-80.

8. Kim KH, Hong JY , Lee H , Kwak GY , Nam CH , Lee SY , Oh E , Yu J , Nahm MH, Kang JH, “Nasopharyngeal pneumococcal carriage of children attending day care centers in Korea: comparison between children immunized with 7-valent pneumococcal conjugate vaccine and non-immunized”, J Korean Med Sci. 2011:26(2):184-90.

9. Lee H, Cho HK, Kim JH and Kim KH, “Seroepidemiology of Hepatitis A in Korea: Changes over the Past 30 Years”, J Korean Med Sci. 2011:26(6):791-6.

10.Kim KH, Kim YK, Kim NH, Chang SH, Lee J, Park EA, Eun BW, Lee H, Oh SM, Shin SH, Bang K, Lee HJ. Immunogenicity and safety of LBVH0101, a new Haemophilus influenzae type b tetanus toxoid conjugate vaccine compared with Hiberix™ in Korean infants and children. Vaccine 2012;30(10):1886-1894.

11. Lee H, Cho HK, Kim KH. Seroepidemiology of Varicella-zoster virus in Korea. J Korean Med Sci 2013;28(2):195-199.

12. Lee H, Cha JH, Nahm MH, Burton RL, Kim KH. The 7-valent pneumococcal conjugate vaccine elicits cross-functional opsonophagocytic killing responses to Streptococcus pneumoniae serotype 6D in children. BMC Infect Dis. 2013:13:474.

13. Cho EY, Lee H, Choi EH, Kim YJ, Eun BW, Cho YK, Kim YK, Jo DS, Lee HS, Lee J, Kim MN, Kim DS, Lee HJ. Serotype distribution and antibiotic resistance of Streptococcus pneumoniae isolated from invasive infections after optional use of the 7-valent conjugate vaccine in Korea, 2006-2010. Diag Microbiol Infect Dis. 2014 Apr;78:481-486.

14. Lee H, Kim ES, Choi C, Seo H, Shin M, Bok JH, Cho JE, Kim CJ, Shin JW, Kim TS, Song KH, Park KU, Kim BI, Kim HB. Outbreak among healthy newborns due to a new variant of USA300-related meticillin-resistant Staphylococcus aureus. J Hosp Infect. 2014 Jul;87(3):145-51.

15. Choi JH, Yang NR, Lee WJ, Lee H, Choi EH, Lee HJ. “Distribution of emm types among group A streptococcus isolates from children in Korea”, Diagn Microbiol Infect Dis. 2015 May;82(1):26-31.

16. Choe YH, Lee H, Choi EH, Lee HJ. Antiviral treatment of Influenza in South Korea. Expert Review in Anti-infective Therapy. 2015 Jun;13(6):741-9.

17. Yoon IA, Jo DS, Cho EY, Choi EH, Lee HJ, Lee H. Clinical Significance of Serotype V among Infants with Invasive Group B Streptococcal Infections in South Korea. Int J Infect Dis. 2015 Sep;38:136-40.

18. Yun KW, Lee H, Choi EH, Lee HJ. Diversity of Pneumolysin and Pneumococcal Histidine Triad Protein D of Streptococcus pneumoniae Isolated from Invasive Diseases in Korean Children. PLoS One. 2015 Aug 7;10(8):e0134055.

19. Kang HM, Lee HJ, Cho EY, Yu KS, Lee H, Lee JW, Kang HJ, Park KD, Shin HY, Choi EH. The Clinical Significance of Voriconazole Therapeutic Drug Monitoring in Children With Invasive Fungal Infections. Pediatr Hematol Oncol. 2015 Nov;32(8):557-67.

20. Han MS, Lee HJ, Lee H, Choe YJ, Lee JW, Kang HJ, Park KD, Shin HY, Jung HJ, Choi EH. Risk Factors and Clinical Features of Cytomegalovirus Disease in Children Receiving Anticancer Chemotherapy. J Pediatr Hematol Oncol. 2016 Apr;38(3):e113-9.

21. Kang HM, Choi EH, Lee HJ, Yun KW, Lee CK, Cho TJ, Cheon JE, Lee H. The Etiology, Clinical Presentation and Long-term Outcome of Spondylodiscitis in Children. Pediatr Infect Dis J. 2016 Apr;35(4):e102-6.

22. Kang HM, Kim JY, Choi EH, Lee HJ, Yun KW, Lee H. Clinical Characteristics of Severe Histiocytic Necrotizing Lymphadenitis (Kikuchi-Fujimoto Disease) in Children. J Pediatr. 2016 Apr;171:208-212.e1.

23. Lee HJ, Choe YJ, Hong YJ, Kim KH, Park SE, Kim YK, Oh CE, Lee H, Song H, Bock H, Casula D, Bhusal C, Arora AK. Immunogenicity and safety of a multicomponent meningococcal serogroup B vaccine in healthy adolescents in Korea-A randomised trial. Vaccine. 2016 Feb 24;34(9):1180-6.

24. Cho EY, Choi EH, Kang JH, Kim KH, Kim DS, Kim YJ, Ahn YM, Eun BW, Oh SH, Cha SH, Cho HK, Hong YJ, Kim KN, Kim NH, Kim YK, Kim JH, Lee H, Lee T, Kim HM, Lee KS, Kim CS, Park SE, Kim YM, Oh CE, Ma SH, Jo DS, Choi YY, Lee J, Bae GR, Park O, Park YJ, Kim ES, Lee HJ. Early Changes in the Serotype Distribution of Invasive Pneumococcal Isolates from Children after the Introduction of Extended-valent Pneumococcal Conjugate Vaccines in Korea, 2011-2013. J Korean Med Sci. 2016 Jul; 31(7): 1082?1088.

25. Cho HK, Lee H, Kim HW, Kim SS, Kang HJ, Kim IT, Kim KH. Seroprevalences of Specific IgG Antibodies to Measles, Mumps, and Rubella in Korean Infants. J Korean Med Sci. 2016 Dec;31(12):1957-1962.

26. Choe YJ, Lee HJ, Lee H, Oh CE, Cho EY, Choi JH, Kang HM, Yoon IA, Jung HJ, Choi EH. Emergence of antibiotic-resistant non-vaccine serotype pneumococci in nasopharyngeal carriage in children after the use of extended-valency pneumococcal conjugate vaccines in Korea. Vaccine. 2016 Sep 14;34(40):4771-6.

27. Kim HW, Lee JH, Cho HK, Lee H, Seo HS, Lee S, Kim KH. Opsonophagocytic Antibodies to Serotype Ia, Ib, and III Group B Streptococcus among Korean Infants and in Intravenous Immunoglobulin Products. J Korean Med Sci. 2017 May;32(5):737-743.

28. Kang HM, Lee HJ, Lee H, Jo DS, Lee HS, Kim TS, Shin JH, Yun KW, Lee B, Choi EH. Genotype Characterization of Group B Streptococcus Isolated from Infants with Invasive Diseases in South Korea. Pediatr Infect Dis J. 2017 Oct;36(10):e242-e247.

29. Kim JY, Lee H, Yun B. Ultrasonographic findings of Kikuchi cervical lymphadenopathy in children. Ultrasonography. 2017 Jan;36(1):66-70.

30. Yoon IA, Hong KB, Lee HJ, Yun KW, Park JY, Choi YH, Kim WS, Lee H, Eun BW, Ahn YM, Cho EY, Cho HJ, Choi EH. Radiologic findings as a determinant and no effect of macrolide resistance on clinical course of Mycoplasma pneumoniae pneumonia. BMC Infect Dis. 2017 Jun 7;17(1):402.

31. Kim YK, Vidor E, Kim HM, Shin SM, Lee KY, Cha SH, Ma SH, Kim DH, Lee J, Park SE, Lee H, Kim JD, Kim KH, Kim KH, Kim JH; A3L31 Study Group. Immunogenicity and safety of a fully liquid DTaP-IPV-HB-PRP∼T hexavalent vaccine compared with the standard of care in infants in the Republic of Korea. Vaccine. 2017 Jul 13;35(32):4022-4028.

32. Kim S, Moon HM, Lee JK, Rhie K, Yoon KW, Choi EH, Lee HJ, Lee H. Changes in trends and impact of testing for influenza in infants with fever <90 days of age. Pediatr Int. 2017 Dec;59(12):1240-1245.

33. Lee H, Lim SY, Kim KH. Validation of the World Health Organization Enzyme-Linked Immunosorbent Assay for the Quantitation of Immunoglobulin G Serotype-Specific Anti-Pneumococcal Antibodies in Human Serum. J Korean Med Sci. 2017 Oct;32(10):1581-1587.

34. Lee H, Yun KW, Lee HJ, Choi EH. Antimicrobial therapy of macrolide-resistant

Mycoplasma pneumoniae pneumonia in children. Expert Rev Anti Infect Ther. 2018 Jan;16(1):23-34.

35. Shim YJ, Choi BY, Park KH, Lee H, Jung YM, Kim YM. Inflammatory and Immune Proteins in Umbilical Cord Blood: Association with Hearing Screening Test Failure in Preterm Neonates. Mediators Inflamm. 2018:4209359.

36. Han MS, Yun KW, Lee HJ, Park JY, Rhie K, Lee JK, Lee H, Kwak YH, Kim DK, Suh DI, Choi EH. Contribution of Co-Detected Respiratory Viruses and Patient Age to the Clinical Manifestations of Mycoplasma Pneumoniae Pneumonia in Children. Pediatr Infect Dis J. 2018;37:531?536.

37. Lee JK, Lee JH, Lee H, Ahn YM, Eun BW, Cho EY, Cho HJ, Yun KW, Lee HJ, Choi EH. Clonal Expansion of Macrolide-Resistant Sequence Type 3 Mycoplasma pneumoniae, South Korea. Emerg Infect Dis. 2018 Aug;24(8):1465-1471.

38. Yun KW, Choi EH, Lee HJ, Kang JH, Kim KH, Kim DS, Kim YJ, Eun BW, Oh SH, Cho HK, Hong YJ, Kim KN, Kim NH, Kim YK, Lee H, Lee T, Kim HM, Cho EY, Kim CS, Park SE, Oh CE, Jo DS, Choi YY, Lee J. Genetic structures of invasive Streptococcus pneumoniae isolates from Korean children obtained between 1995 and 2013. BMC Infect Dis. 2018 Jun 8;18(1):268.

39. Lee H. Importance of Functional Assessment of Immunity against Group B Streptococcus. J Korean Med Sci. 2018 Apr 16;33(16):e129. doi: 10.3346/jkms.2018.33.e129.

40. Lee H. Outbreak Investigation of Scarlet Fever in a Kindergarten. Infect Chemother. 2018 Mar;50(1):65-66. doi: 10.3947/ic.2018.50.1.65.

41. Kim YT, Serrano B, Lee JK, Lee H, Lee SW, Freeman C, Oh JK, Alemany L, Bosch FX, Bruni L. Burden of Human papillomavirus (HPV)-related disease and potential impact of HPV vaccines in the Republic of Korea. Papillomavirus Res. 2018 Dec 30;7:26-42.

42. Lee H, Hur S, Jang H, Lee IH, Sohn WY, Van Kriekinge G, Kim BG. Cost-Utility of a Two-Dose Human Papillomavirus Vaccination Programme Added to Cervical Cancer Screening Compared with Cervical Cancer Screening Alone in Korea. Asian Pac J Cancer Prev. 2019 Feb 26;20(2):425-435.

43. Kim SY, Park JS, Hong YJ, Kim TS, Hong K, Song KH, Lee H, Kim ES, Kim HB, Park KU, Song J, Koo SH, Kim EC. Microarray-Based Nucleic Acid Assay and MALDI-TOF MS Analysis for the Detection of Gram-Negative Bacteria in Direct Blood Cultures. Am J Clin Pathol. 2019 Jan 7;151(2):143-153.

44. Choi EH, Park SE, Kim YJ, Jo DS, Kim YK, Eun BW, Lee TJ, Lee J, Lee H, Kim KH, Cho HK, Cho EY, Kim JH. Recommended Immunization Schedule for Children and Adolescents: Committee on Infectious Diseases of the Korean Pediatric Society, 2018. Korean J Pediatr. 2019 Jul;62(7):252-256.

45. Lee HJ, Jo DS, Kim YK, Lee H, Kim KH, Lee D, et al. One-year antibody persistence and safety of a 4-dose schedule of MenACWY-CRM in healthy infants from South Korea. Clin Exp Vaccine Res. 2019 Jul;8(2):94-102.

46. Yun KW, Park SH, Cho EY, Lee H. Clinical Features and Outcomes of Community-Acquired Late-Onset Sepsis. Pediatr Int. 2019 Dec;61(12):1210-1215.

47. Han SH, Park JW, Choi SI, Kim JY, Lee H, Yoo HJ, Ryu JH. Effect of Immersive Virtual Reality Education Before Chest Radiography on Anxiety and Distress Among Pediatric Patients: A Randomized Clinical Trial. JAMA Pediatr 2019.

48. Park SG, Kim H, Paik JH, Park KU, Park JS, Jeong WJ, Jung YH, Na JI, Sung KH, Kim JY, Lee H, Lee H. Cluster of Lymphadenitis due to Nontuberculous Mycobacterium in Children and Adolescents 8-15 Years of Age. J Korean Med Sci. 2019 Dec 2;34(46):e302.

49. Park SG, Lee HS, Park JY, Lee H. Molecular Epidemiology of Staphylococcus aureus in Skin and Soft Tissue Infections and Bone and Joint Infections in Korean Children. J Korean Med Sci. 2019 Dec 23;34(49):e315.

저서

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보도자료

백신, 정해진 횟수 맞아야 효과… 접종력 모르겠다면 다시 맞아야
https://news.naver.com/main/read.nhn?mode=LSD&mid=sec&sid1=103&oid=346&aid=0000024468

수두까지 확산… 이달에만 환자 5427명
https://news.naver.com/main/read.nhn?mode=LSD&mid=sec&sid1=102&oid=023&aid=0003423302

“우리아이 건강, ‘대변(大便)’ 살펴보면 알 수 있어요”
http://www.k-health.com/news/articleView.html?idxno=40097

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