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  #임상화학#임상면역#세포치료학

학력

연세의대 졸업
연세대학교 석사 (의학)
연세대학교 박사 (의학)

경력

진단검사의학 전공의, 연세의대 세브란스병원
전임강사, 연세의대 세브란스병원
조교수, 연세의대 세브란스병원
부교수, 연세의대 세브란스병원

연세대학교 박사 (의학)
미국국립보건원 (NIH), Post-doctor fellowship
University of Washing Medicine, Tumor Vaccine Group, 방문교수
Harvard Medical School, Mesachuesset General Hospital, 방문교수

논문

Park Q, Lim JB, Yi KS, Kim MJ, Kim HO, Song KS. Platelet Transfusion Support for Splenectomy in Patients with Chronic Immune Thrombocytopenic Purpura. Korean J Blood Transfusion 9:201-8, 1998

Lim JB, Kim MJ, Yi KS, Lee SM, Kim HO. Evaluation of the Collection Efficiency of the Granulocyte in Leukapheresis Using 10% Pentastarch. Korean J Clin Pathol 19: 125-30, 1999

Lim JB, Kim HS, Park Q, Lee SK, Park YB, Han CT. Clinical Significance of Anti-HSP 70 Antibody in Patients with Systemic Lupus Erythematosus. Korean J Clinical Pathol 19: 548-53,1999

Yi KS, Lim JB, Kim HK, Park Q, Song KS, Kim KY. A Case of Glanzmann’s Thrombasthenia with Unusual Platelet Aggregation Response. Korean J Hemostasis Thromb 6:131-36,1999

Lyu CJ, Park SH, Cho HS, Kim HO, Lim JB, Park SM, Yang CH, Kim KY, Cho JS, Park YW. Method of RBC Depletion from Human Umbilical Cord Blood. Korean J Ped Hematol Oncol 5:163-70, 1998

Chong Y, Lee K, Shin JW, Shin HB, Lim JB. Activity of Arbekacin Against Methicillin-resistant Staphylococcus Aureus and Pseudomonas Aeruginosa. J Korean Society Chemoth 15:319-27, 1997

Kim MJ, Lee SM, Lim JB, Yi KS, Park Q, Kim HO, Song KS. Determining the Optimal Time for Peripheral Blood Stem Cell Harvest by Detecting Immature Cells using Hematology Analyzer, SE-9000TM IMI Channel. Korea J Clin Pathol 4:252-57, 1999

Lee K, Shin JW, Lim JB, Kim YA, Yong D, Oh HB, Chong Y. Emerging antimicrobial resistance, plasmid profile and pulsed-field gel electrophoresis pattern of the endonuclease-digested genomic DNA of Neisseria gonorrhoeae. Yonsei Med J 41(3):381-6, 2000

Lee K, Lim JB, Yum JH, Yong D, Chong Y, Kim JM, Livermore DM. bla(VIM-2) cassette-containing novel integrons in metallo-beta-lactamase-producing Pseudomonas aeruginosa and Pseudomonas putida isolates disseminated in a Korean hospital. Antimicrob Agents Chemother 2002;46:1053-8

Kim HS, Lim JB, Min YH, Lee ST, Lyu CJ, Kim ES, Kim HO. Ex Vivo Expansion of Human Umbilical Cord Blood CD34+ Cells in a Collagen Bead-Containing 3-Dimensionla Culture System. Int J Hematol 2003;78:126-132

Provenzano M, Lim JB, Mocellin S, Monsurro V, Bettinotti M, Marincola FM, Stroncek DF. The matrix protein pp65(341-350): a peptide that induces ex vivo stimulation and in vitro expansion of CMV-specific CD8+ T cells in subjects bearing either HLA-A*2402 or A*0101 allele. Transfusion. 2003 Nov; 43(11): 1567-74

Dittmar K, Lim JB, Caruccio L, Bettinotti M, Stroncek D. Assessment of the relative number of copies of the gene encoding human neutrophil antigen-2a (HNA-2a), CD177, and a homologous pseudogene by quantitative real-time PCR. Immunohematology 2003:19;122-126.

Slota M, Lim JB, Dang Y, Disis ML. ELISpot for measuring human immune responses to vaccines.. Expert Rev Vaccines. 2011 Mar;10(3):299-306.

Chung HW, Jang S, Lim JB. Clinical implications and diagnostic usefulness of correlation between soluble major histocompatibility complex class I chain-related molecule a and protumorigenic cytokines in pancreatic ductal adenocarcinoma. Cancer. 2012 Jun 26.

Adoptive immunotherapy for Cytomegalovirus (CMV) disease in immunocompromised patients
YONSEI MEDICAL JOURNAL 45/ :18-22,2004

CMV 질환의 면역치료법 개발에 대한 최신지견
건국의과학학술지(The Konkuk Journal. Of Medical Sciences) 13/2 :-,2004

PREG-Qtm를 이용한 체외임신반응검사의 임상적 유용성 평가
임상검사와 정도관리 26/1 :207-210,2004

Effectiveness of real-time quantitative PCR compare to repeat PCR for the diagnosis of Charcot-Marie-Tooth type 1A and hereditary neuropathy with liability to pressure palsies
YONSEI MEDICAL JOURNAL 46/3 :347-352,2005

TDM검사 신빙도조사 결과보고(2004)
임상검사와 정도관리 27/1 :111-124,2005

Identification of HLA-A33-restricted CMV pp65 epitopes as common targets for CD8
EXPERIMENTAL HEMATOLOGY 34/ :296-307,2006

TDM검사 신빙도조사 결과보고(2005)
임상검사와 정도관리 28/1 :121-134,2006

유지 혈액투석 환자에서 단기간의 빈혈 개선에 따른 혈중 Amino-Terminal Pro B-type NatriureticPeptide (NT-pro BNP)치 및 심초음파 소견의 변화
The Korean Journal of Nephrology 25/5 :803-811,2006

TDM검사 신빙도조사 결과보고(2006)
임상검사와 정도관리 29/1 :121-135,2007

다양한 신질환을 가진 소아에서 Cystatin C 검사의임상적 유용성
대한소아신장학회지 11/2 :161-167,2007

TDM 및 약물남용검사 신빙도조사 결과보고(2007)
임상검사와 정도관리(Journal of Laboratory Medicine and Quality Assurance) 30/1 :133-149,2008

Cytokine Profile of Peripheral Blood in Type 2 Diabetes Mellitus Patients with Diabetic Retinopathy
Annals Of Clinical And Laboratory Science 38/ :361-367,2008

Comparison of the Validity of Three Biomarkers for Gastric Cancer Screening Carcinoembryonic Antigen, Pepsinogens, and High Sensitive C-reactive Protein
Journal Of Clinical Gastroenterology 43/1 :19-26,2009

Effect of Intravitreal Bevacizumab Injection on Aqueous Humor Cytokine Levels in Clinically Significant Macular Edema
Ophthalmology 116/ :80-86,2009

Serum high mobility group box-1 (HMGB1) is closely associated with the clinical and pathologic features of gastric cancer
Journal of Translational Medicine 7/ :38-48,2009

Expression of interleukin-5 and tumor necrosis factor alpha in cervical carcinoma
Clinical And Vaccine Immunology 16/6 :959-961,2009

Concentration of cytokines in the aqueous humor of patients with naive, recurrent and regressed cnv associated with amd after bevacizumab treatment
Retina-The Journal Of Retinal And Vitreous Diseases 29/4 :523-529,2009

Radiosensitization Effect of STI-571 on Pancreatic Cancer Cells In Vitro
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 75/3 :862-869,2009

Identification of HLA-A*2402-restricted HCMV immediate early-1 (IE-1) epitopes as targets for CD8+HCMV-specific cytotoxic T lymphocytes
Journal of Translational Medicine 7/1 :72-83,2009

Functional Recovery After the Transplantation of Neurally Differentiated Mesenchymal Stem Cells Derived From Bone Barrow in a Rat Model of Spinal Cord Injury
Cell Transplantation 18/12 :1359-1368,2009

Outbreak by meropenem-resistant Pseudomonas aeruginosa producing IMP-6 metallo-β-lactamase in a Korean hospital
Diagnostic Microbiology And Infectious Disease 63/1 :115-117,2009

Axillary Lymph Node Metastasis: CA-15-3 and Carcinoembryonic Antigen Concentrations in Fine-Needle Aspirates for Preoperative Diagnosis in Patients with Breast Cancer
RADIOLOGY 254/ :691-697,2010

Analysis of demographic characteristics in 3242 young age gastric cancer patients in Korea
WORLD JOURNAL OF GASTROENTEROLOGY 16/2 :256-263,2010

Panel of Candidate Biomarkers for Renal Cell Carcinoma
Journal of Proteome Research 9/7 :3710-3719,2010

Development of a serum-free medium for in vitro expansion of human cytotoxic T lymphocytes using a statistical design
Bmc Biotechnology 10/ :70-70,2010

Concentration of cytokines in age-related macular degeneration after consecutive intravitreal bevacizumab injection
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 248/5 :635-640,2010

Clinical significance of serum levels of immune-associated molecules, uric acid and soluble MHC class I chain-related molecules A and B, as diagnostic tumor markers for pancreatic ductal adenocarcinoma
CANCER SCIENCE 102/9 :1673-1679,2011

ELISpot for measuring human immune responses to vaccines
EXPERT REVIEW OF VACCINES 10/3 :299-306,2011

Cell-to-Cell Contact with Hepatitis C Virus-Infected Cells Reduces Functional Capacity of Natural Killer Cells
JOURNAL OF VIROLOGY 85/23 :12557-12569,2011

Identification of novel immunogenic human leukocyte antigen-A*2402- binding epitopes of human papillomavirus type 16 E7 for immunotherapy against human cervical cancer
CANCER 118/8 :2173-2183,2012

Serum high mobility group box-1 is a powerful diagnostic and prognostic biomarker for pancreatic ductal adenocarcinoma
CANCER SCIENCE 103/9 :1714-1721,2012

clinical implications and diagnostic usefulness of correlation between soluble major Histocompatibility Complex Class I Chain-Related Molecule A and Protumorigenic Cytokines in Pancreatic Ductal Adenocarcinoma
CANCER 119/1 :233-244,2013

Composite Three-Marker Assay for Early Detection of Kidney Cancer
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 22/3 :390-398,2013

Clinical significance of elevated serum soluble CD40 ligand levels as a diagnostic and prognostic tumor marker for pancreatic ductal adenocarcinoma.
JOURNAL OF TRANSLATIONAL MEDICINE 12/1 :1-9,2014

Identification of Novel Epitopes From Human Papillomavirus Type 18 E7 That Can Sensitize PBMCs of Multiple HLA class I Against Human Cervical Cancer
JOURNAL OF TRANSLATIONAL MEDICINE 12/1 :229-,2014

Clinical significance of serum thymus and activation-regulated chemokine in gastric cancer: Potential as a serum biomarker
CANCER SCIENCE 105/10 :1327-1333,2014

Role of the tumor microenvironment in the pathogenesis of gastric carcinoma
WORLD JOURNAL OF GASTROENTEROLOGY 20/Issue :1667-1680,2014

Clinical significance and usefulness of soluble heparin binding-epidermal growth factor in gastric cancer
WORLD JOURNAL OF GASTROENTEROLOGY 21/7 :2080-2088,2015

Serum ENA78/CXCL5, SDF-1/CXCL12, and their combinations as potential biomarkers for prediction of the presence and distant metastasis of primary gastric cancer
CYTOKINE 73/1 :16-22,2015

Combined targeting of high-mobility group box-1 and interleukin-8 to control micrometastasis potential in gastric cancer
INTERNATIONAL JOURNAL OF CANCER 137/7 :1598-1609,2015

HbA1c for diagnosis and prognosis of gestational diabetes mellitus
DIABETES RESEARCH AND CLINICAL PRACTICE 110/1 :38-43,2015

CD4(+) T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion
IMMUNITY 43/5 :896-908,2015

Ascorbate Oxidase Minimizes Interference by High-Concentration Ascorbic Acid in Total Cholesterol Assays
ANNALS OF LABORATORY MEDICINE 36/26 :188-190,2016

Identificaiton of Novel Immunogenic Human Papillomavirus Type 16 E7-Specific Epitopes Restricted to HLA-A*33;03 for Cervical Cancer Immunotherapy.
YONSEI MEDICAL JOURNAL 58/1 :43-50,2017

Homeostasis model assessment of insulin resistance in a general adult population in Korea: additive association of sarcopenia and obesity with insulin resistance
CLINICAL ENDOCRINOLOGY 86/1 :44-51,2017

High-mobility group box-1 contributes tumor angiogenesis under interleukin-8 mediation during gastric cancer progression
CANCER SCIENCE 108/8 :1594-1601,2017

A Disintegrin and Metalloproteinase 8 as a Potential Blood Biomarker for Early Diagnosis of Gastric Cancer
YONSEI MEDICAL JOURNAL 60/8 :713-719,2019

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