정재민

  #방사성의약품

학력

1984 ~ 1989 서울대학교 대학원 (박사)
1983 ~ 1984 서울대학교 대학원 (석사)
1977 ~ 1982 서울대학교 약학대학 (학사)

경력

2014.02.20 ~ 현재 / 대한방사성의약품학회장
1996. 3 ~ 현 재 / 서울대학교 핵의학교실 조교수, 부교수, 교수
1994. 3 ~ 1996. 2 / 서울대학교 의공학교실 전임강사
1990. 9 ~ 1993. 9 / Natl. Institute Health 핵의학과 연구원
1989. 12 ~ 1990. 9 / 서울대학교병원 핵의학과 자문위원
1985. 5 ~ 1989. 12 / 서울대학교병원 핵의학 연구원
1983. 3 ~ 1983. 12 / 서울대학교 T.A. 약학과

논문

Design and synthesis of enantiopure 18 F-labelled [18 F]trifluoromethyltryptophan from 2-halotryptophan derivatives via copper(I)-mediated [18 F]trifluoromethylation and evaluation of its in vitro characterization for the serotonergic system imaging.

Iging of the third gasotransmitter hydrogen sulfide using 99mTc-labeled alpha-hydroxy acids.

Secreted protein acidic and rich in cysteine mediates active targeting of human serum albumin in U87MG xenograft mouse models.

Development of 99mTc-labeled trivalent isonitrile radiotracer for folate receptor imaging.

A New Metabolic Network Correlated with Olfactory and Executive Dysfunctions in Idiopathic Rapid Eye Movement Sleep Behavior Disorder.

Nonmotor and Dopamine Transporter Change in REM Sleep Behavior Disorder by Olfactory Impairment.

Voxel-Based Dosimetry of Iron Oxide Nanoparticle-Conjugated 177Lu-Labeled Folic Acid Using SPECT/CT Imaging of Mice

Development of 99mTc-labeled trivalent isonitrile radiotracer for folate receptor imaging.

Development of 99mTc-Labeled Human Serum Albumin with Prolonged Circulation by Chelate-then-Click Approach: A Potential Blood Pool Imaging Agent.

Versatile and Finely Tuned Albumin Nanoplatform based on Click Chemistry.

One-pot radiosynthesis of O-[18F]fluoromethyl-D-tyrosine via intra-molecular nucleophilic 18F-fluorination with 1,2,3-triazolium triflate salt precursor.

Loss of toll-like receptor 3 aggravates hepatic inflammation but ameliorates steatosis in mice.

Naphthol Blue Black and 99mTc-Labeled Mannosylated Human Serum Albumin (99mTc-MSA) Conjugate as a Multimodal Lymph Node Mapping Nanocarrier.

Development of a Ga-68 labeled PET tracer with short linker for prostate-specific membrane antigen (PSMA) targeting

Whole-Body Voxel-Based Personalized Dosimetry: The Multiple Voxel S-Value Approach for Heterogeneous Media with Nonuniform Activity Distributions.

18F-FEDAC as a Targeting Agent for Activated Macrophages in DBA/1 Mice with Collagen-Induced Arthritis: Comparison with 18F-FDG.

One-pot radiosynthesis of O-[18F]fluoromethyl-D-tyrosine via intra-molecular nucleophilic 18F-fluorination with 1,2,3-triazolium triflate salt precursor.

Consensus nomenclature rules for radiopharmaceutical chemistry - Setting the record straight.

Noninvasive Imaging of Myocardial Inflammation in Myocarditis using 68Ga-tagged Mannosylated Human Serum Albumin Positron Emission Tomography.

In vivo visualization of endogenous miR-21 using hyaluronic acid-coated graphene oxide for targeted cancer therapy.

Highly robust and optimized conjugation of antibodies to nanoparticles using quantitatively validated protocols.

Preclinical anaylses of [18F]cEFQ as a PET tracer for imaging metabotropic glutamate receptor type 1 (mGluR1)

Image-Based Analysis of Tumor Localization After Intra-Arterial Delivery of Technetium-99m-Labeled SPIO Using SPECT/CT and MRI.

Simultaneous Multiparametric PET/MRI with Silicon Photomultiplier PET and Ultra-High-Field MRI for Small-Animal Imaging.

Macrophage-Targeted Indocyanine Green-Neomannosyl Human Serum Albumin for Intraoperative Sentinel Lymph Node Mapping in Porcine Esophagus.

Angiogenesis Imaging Using (68)Ga-RGD PET/CT: Therapeutic Implications.

Novel PET Imaging of Atherosclerosis with 68Ga-Labeled NOTA-Neomannosylated Human Serum Albumin.

Development of a complementary PET/MR dual-modal imaging probe for targeting prostate-specific membrane antigen (PSMA).

Preclinical evaluation of isostructural Tc-99m- and Re-188-folate-Gly-Gly-Cys-Glu for folate receptor-positive tumor targeting.

Preclinical evaluation of YC-1, a HIF inhibitor, for the prevention of tumor spreading

Stroma targeting nuclear imaging and radiopharmaceuticals

Rapid Hepatobiliary Excretion of Micelle-Encapsulated/Radiolabeled Upconverting Nanoparticles as an Integrated Form.

Noninvasive imaging of radiolabeled exosome-mimetic nanovesicle using (99m)Tc-HMPAO.

Development of 4-hexadecyl-4,7-diaza-1,10-decanedithiol (HDD) kit for the preparation of the liver cancer therapeutic agent Re-188-HDD/lipiodol.

Development of a multimodal imaging probe by encapsulating iron oxide nanoparticles with functionalized amphiphiles for lymph node imaging.

Ga-68-labeled neolactosylated human serum albumin (LSA) for PET imaging of hepatic asialoglycoprotein receptor.

Gallium-68 neomannosylated human serum albumin-based PET/CT lymphoscintigraphy for sentinel lymph node mapping in non-small cell lung cancer.

Comparative assessment of parametric neuroreceptor mapping approaches based on the simplified reference tissue model using [11C]ABP688 PET.

Development of (68)Ga-labeled multivalent nitroimidazole derivatives for hypoxia imaging

Development of a complementary PET/MR dual-modal imaging probe for targeting prostate-specific membrane antigen (PSMA)

Lymph node imaging using novel simultaneous PET/MRI and dual-modality imaging agent

In vivo evaluation of angiogenic activity and its correlation with efficacy of indirect revascularization surgery in pediatric moyamoya disease

Large-scale plastic changes of the brain network in an animal model of neuropathic pain

In vivo imaging of mGluR5 changes during epileptogenesis using [11C]ABP688 PET in pilocarpine-induced epilepsy rat model

Preparation of Ga-68-NOTA as a renal PET agent and feasibility tests in mice

Correlation of breast cancer subtypes, based on estrogen receptor, progesterone receptor, and HER2, with functional imaging parameters from ??Ga-RGD PET/CT and ?F-FDG PET/CT

Thoracoscopic color and fluorescence imaging system for sentinel lymph node mapping in porcine lung using indocyanine green-neomannosyl human serum albumin: intraoperative image-guided sentinel nodes navigation

Hypoxia imaging agents labeled with positron emitters

Quantitative positron emission tomography imaging of angiogenesis in rats with forelimb ischemia using (68)Ga-NOTA-c(RGDyK)

The relationship between antipsychotic D2 occupancy and change in frontal metabolism and working memory : A dual [(11)C]raclopride and [(18)?F]FDG imaging study with aripiprazole

Angiogenesis imaging in myocardial infarction using 68Ga-NOTA-RGD PET: characterization and application to therapeutic efficacy monitoring in rats

Imaging of integrin α(V)β(3) expression using (68)Ga-RGD positron emission tomography in pediatric cerebral infarct

Feasibility and kinetic characteristics of (68)Ga-NOTA-RGD PET for in vivo atherosclerosis imaging

Nanoparticles modified by encapsulation of ligands with a long alkyl chain to affect multispecific and multimodal imaging

Compartmental modeling and simplified quantification of [뭐C]sertraline distribution in human brain

Development of a bifunctional chelating agent containing isothiocyanate residue for one step F-18 labeling of peptides and application for RGD labeling

A positron emission tomography microdosing study with sertraline in healthy volunteers

Whole-body distribution and radiation dosimetry of (68)Ga-NOTA-RGD, a positron emission tomography agent for angiogenesis imaging

Development and in vivo imaging of a PET/MRI nanoprobe with enhanced NIR fluorescence by dye encapsulation

Syntheses of 2-nitroimidazole derivatives conjugated with 1,4,7-triazacyclononane-N,N'-diacetic acid labeled with F-18 using an aluminum complex method for hypoxia imaging

Predicting brain occupancy from plasma levels using PET: superiority of combining pharmacokinetics with pharmacodynamics while modeling the relationship

Comparison between preoperative versus intraoperative injection of technetium-99 m neomannosyl human serum albumin for sentinel lymph node identification in early stage lung cancer

Evaluation of (111)In-labeled macrocyclic chelator-amino acid derivatives for cancer imaging

Stable aluminium fluoride chelates with triazacyclononane derivatives proved by X-ray crystallography and (18)F-labeling study

The use of healthy volunteers instead of patients to inform drug dosing studies: a [11C]raclopride PET study

Aromatic radiofluorination and biological evaluation of 2-aryl-6-[18F]fluorobenzothiazoles as a potential positron emission tomography imaging probe for β-amyloid plaques

A brain-targeted rabies virus glycoprotein-disulfide linked PEI nanocarrier for delivery of neurogenic microRNA

Calculating occupancy when one does not have baseline: a comparison of different options

Synthesis of 68Ga-labeled DOTA-nitroimidazole derivatives and their feasibilities as hypoxia imaging PET tracers

Development of (68)Ga-labeled mannosylated human serum albumin (MSA) as a lymph node imaging agent for positron emission tomography

Development of small-animal PET prototype using silicon photomultiplier (SiPM): initial results of phantom and animal imaging studies

Formation and Characterization of Gallium(III) Complexes with Monoamide Derivatives of 1,4,7-Triazacyclononane-1,4,7-triacetic Acid: A Study of the Dependency of Structure on Reaction pH

Facile Chlorination of Benzyl Alcohols Using 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) and Sulfonyl Chlorides

Synthesis and characterization of nitroimidazole derivatives for 68Ga-labeling and testing in tumor xenografted mice

Synthesis of novel 68Ga-labeled amino acid derivatives for positron emission tomography of cancer cells.

Synthesis and evaluation of macrocyclic amino acid derivatives for tumor imaging by gallium-68 positron emission tomography

A new PET probe, (18)F-tetrafluoroborate, for the sodium/iodide symporter: possible impacts on nuclear medicine

Formulation of 68Ga BAPEN kit for myocardial positron emission tomography imaging and biodistribution study

Wild-type p53 enhances the cytotoxic effect of radionuclide gene therapy using sodium iodide symporter in a murine anaplastic thyroid cancer model

Development of a (177)Lu-Labeled RGD Derivative for Targeting Angiogenesis.

In Vivo Imaging of Sentinel Nodes Using Fluorescent Silica Nanoparticles in Living Mice

(18)F-Labeled benzylideneaniline derivatives as new ligands for beta-amyloid plaque imaging in Alzheimer's disease.

Visualization of hypoxia-inducible factor-1 transcriptional activation in C6 glioma using luciferase and sodium iodide symporter genes

Loss of asymmetry in D2 receptors of putamen in unaffected family members at increased genetic risk for schizophrenia

Real-time in vivo monitoring of viable stem cells implanted on biocompatible scaffolds

Comparison of FDG-PET findings of brain metastasis from non-small-cell lung cancer and small-cell lung cancer

Preparation of a promising angiogenesis PET imaging agent: 68Ga-labeled c(RGDyK)-isothiocyanatobenzyl-1,4,7-triazacyclononane-1,4,7-triacetic acid and feasibility studies in mice.

Use of the Oak Ridge National Laboratory tungsten-188/rhenium-188 generator for preparation of the rhenium-188 HDD/lipiodol complex for trans-arterial liver cancer therapy.

International Atomic Energy Agency-sponsored multination study of intra-arterial rhenium-188-labeled lipiodol in the treatment of inoperable hepatocellular carcinoma: results with special emphasis on prognostic value of dosimetric study

Differential receptor targeting of liver cells using 99mTc-neoglycosylated human serum albumins.

Noninvasive in vivo monitoring of neuronal differentiation using reporter driven by a neuronal promoter

Development of a Dual-Luciferase Reporter System for In Vivo Visualization of MicroRNA Biogenesis and Posttranscriptional Regulation

In vivo bioluminescence visualization of antitumor effects by human MUC1 vaccination

Doxorubicin Enhances the Expression of Transgene Under Control of the CMV Promoter in Anaplastic Thyroid Carcinoma Cells

Human sodium iodide symporter gene adjunctive radiotherapy to enhance the preventive effect of hMUC1 DNA vaccine

Immune response to firefly luciferase as a naked DNA

In vivo long-term imaging and radioiodine therapy by sodium-iodide symporter gene expression using a lentiviral system containing ubiquitin C promoter

Development of acetylated HDD kit for preparation of 188Re-HDD/lipiodol

Assessment of regional GABA(A) receptor binding using (18)F-fluoroflumazenil positron emission tomography in spastic type cerebral palsy

Modeling of brain D2 receptor occupancy-plasma concentration relationships with a novel antipsychotic, YKP1358, using serial PET scans in healthy volunteers

Apoptosis-inducing antitumor efficacy of hexokinase II inhibitor in hepatocellular carcinoma

Intra-arterial rhenium-188 lipiodol in the treatment of inoperable hepatocellular carcinoma: results of an IAEA-sponsored multination study

Development of a Dual Membrane Protein Reporter System Using Sodium Iodide Symporter and Mutant Dopamine D2 Receptor Transgenes

Radiation synovectomy using 188Re-tin colloid improves knee synovitis as shown by MRI in refractory rheumatoid arthritis

Synthesis and evaluation of benzothiophene dervatives as ligands for imaging beta-amyloid plaques in Alzheimer`s diseas.

Evaluation of transcriptional activity of the oestrogen receptor with sodium iodide symporter as an imaging reporter gene

The clinical impact of 18F-FDG PET in papillary thyroid carcinoma with a negative 131I whole body scan: a single -center study of 108 patients

188Re-HDD/lipiodol therapy for hepatocellular carcinoma: an activity escalation study

An improved method of 18F peptide labeling: hydrazone formation with HYNIC-conjugated c(RGDyK)

In vivo monitoring of DNA vaccine gene expression using firefly luciferase as a naked DNA

Usefulness of Additional Delayed Regional F-18 Fluorodeoxy-glucose Positron Emission Tomography in the Lymph Node Staging of Non-Small Cell Lung Cancer Patients

Ionic Liquid mediated efficient reduction of nitroarenes using stannous chloride under sonication.

Development of a Sodium/Iodide Symporter (NIS)-Transgenic Mouse for Imaging of Cardiomyocyte-Specific Reporter Gene Expression

188Re-HDD/Lipiodol Therapy for Hepatocellular Carcinoma: A Phase I Clinical Trial

Visualization of endogenous p53-mediated transcription in vivo using sodium iodide symporter

11C-methionine PET as a prognostic marker in patients with glioma: comparison with(18)F-FDG PET

Preparation of 18F-human serum albumin: a simple and efficient protein labeling method with 18F using a hydrazone-formation method.

Voxel-based statistical analysis of cerebral glucose metabolism in the rat cortical deafness model by 3D reconstruction of brain from autoradiographic images

11C-methionine PET as a prognostic marker in patients with glioma: comparison with(18)F-FDG PET

The relationship between expression of the sodium/iodide symporter gene and the status of hormonal receptors in human breast cancer tissue

Biological properties of 2'-[(18)F]fluoroflumazenil for central benzodiazepine receptor imaging.

Correlation between serum CEA level and metabolic volume as determined by FDG PET in postoperative patients with recurrent colorectal cancer

188Re-HDD/Lipiodol for Treatment of Hepatocellular Carcinoma: A Feasibility Study in Patients with Advanced Cirrhosis

In vitro and in vivo properties of a human anaplastic thyroid carcinoma cell line transfected with the sodium iodide symporter gene

저서

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보도자료

'방사선의 재발견'… 난치병 치료제로 각광
http://health.hankyung.com/article/2018032127861

[대세로 떠오른 방사성의약품⑤-끝] 30년을 함께 한 방사성의약품...
https://cp.news.search.daum.net/p/84128616

방사선의약품 분야 "약사 직능범위 기억해 달라"
https://cp.news.search.daum.net/p/46571339

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