이재협

  #감염#골다공증#목디스크#미세척추수술 및 내시경수술#신경마비#요추 추간판 탈출증#종양#척수증#척추 골절#척추 측만증#척추관 협착증

학력

서울대학교 의과대학 의학박사 (2004.2)
서울대학교 의과대학 졸업 (1995.3)

경력

서울특별시 보라매병원 진료부원장 및 공공의료사업단장 (2019.6 -)
서울대학교 의과대학 의예과 학과장 (2016.6 -2019.5)
서울대학교 의과대학 교수 (2015.3 - 정년)
보라매병원 관절척추센터 센터장 (2010 ? 2019.6)
보라매병원 정형외과 과장 (2010 - 2012.1, 2016.9 -2019.6)
서울대학교 의과대학 조교수, 부교수 (2005.9 -2015.2)
정형외과 전문의 (2000.3)
가천의대 중앙길병원 정형외과 조교수 (2004.3 ? 2005.8)
서울대학교병원 정형외과 임상전임의(척추) (2003.3 - 2004.2)
서울대학교병원 정형외과 연구전임의(척추, 인공골) (2002.3 - 2003.2)
9공수 특전여단 의무과장 (2000 - 2002)
서울대학교병원 정형외과 전공의 (1996.3-2000.2)

논문

Characterization of CaO-SiO2-B2O3 Glass-Ceramics and Effect of Composition on Bioactivity. H. S. Ryu, J. H. Seo, H. Kim, K. S. Hong, H. J. Park, D. J. Kim, J. H. Lee, D. H. Lee, B. S. Chang, C. K. Lee. Key Engineering Materials, 240-242: 261-264, 2003

Fabrication of CaO-SiO2-B2O3 Porous Glass-Ceramics by Self-Foaming Method. J. H. Seo, H. S. Ryu, K. S. Hong, H. Kim, D. J. Kim, J. H. Lee, D. H. Lee, C. K. Lee. Key Engineering Materials, 240-242: 273-276, 2003

Porous Beta-Calcium Pyrophosphate as a Bone Graft Substitute in a Canine Bone Defect Model. J. H. Lee, D. H. Lee, H. S. Ryu, B. S. Chang, K. S. Hong, C. K. Lee. Key Engineering Materials, 240-242: 399-402, 2003

Novel Bioactive and Biodegradable Glass-Ceramics with high mechanical strength in the CaO-SiO2-B2O3 system. Hyun-Seung Ryu, Jung-Kun Lee, Jun-Hyuk Seo, Hwan Kim, Kug Sun Hong, Deug Joong Kim, Jae Hyup Lee, Dong-Ho Lee, Bong-Soon Chang, Choon-Ki Lee and Sung-Soo Chung. Journal of Biomedical and Materials Research, 68-A(1): 79 ? 89, 2004, jan.

Magnesia doped-HA/β-TCP ceramics and evaluation of their biocompatibility. Hyun-Seung Ryu, Kug Sun Hong, Jung-Kun Lee, Deug Joong Kim, Jae Hyup Lee, Bong-Soon Chang, Dong-Ho Lee, Choon-Ki Lee and Sung-Soo Chung. Biomaterials, 25(3): 393-401, 2004, feb.

Fabrication of 1 Dimensional Porous Hydroxyapatite and Evaluation of Its Osteoconductivity. Hyun-Seung Ryu, Su-Jin Kim, Jin-Ho Kim, Hwan Kim, Kug Sun Hong, Bong-Soon Chang, Dong-Ho Lee, Jae Hyup Lee, Choon-Ki Lee and Sung-Soo Chung. Journal of Materials Science and Materials in Medicine, 15(3): 267 ? 273, 2004, march.

Characterization of Bioactive Glass-Ceramics Prepared by Sintering Mixed Glass Powders of Cerabone A-W type Glass/CaO-SiO2-B2O3 Glass. J. H. Seo, H. S. Ryu, K. S. Park, K. S. Hong, H. Kim, J. H. Lee, D. H. Lee, B. S. Chang, C. K. Lee. Key Engineering Materials, 254-256: 147-150, 2004.

Effect of B2O3 on the Sintering Behavior and Phase Transition of Wollastonite Ceramics. K. S. Park, H. S. Ryu, J. H. Seo, K. S. Hong, H. Kim, J. H. Lee, D. H. Lee, B. S. Chang, C. K. Lee. Key Engineering Materials, 254-256: 151-154, 2004.

The Effect of Calcium Pyrophosphate Coating on the Fixation of Titanium Screws ?An In Vivo Study-. Jae Hyup Lee, Hyun-Seung Ryu, Dong-Soo Lee, Kug Sun Hong, Bong-Soon Chang, Choon-Ki Lee. Key Engineering Materials, 284-286: 219-222, 2005.

BIOMECHANICAL, RADIOMORPHOMETRIC EVALUATION OF CAO-SIO2-B2O3 GLASS-CERAMICS IN A RABBIT LUMBAR FUSION MODEL. Jae Hyup Lee, Hyun-Seung Ryu, Jun-Hyuk Seo, Hwan Kim, Kug Sun Hong, Bong-Soon Chang, Choon-Ki Lee. Key Engineering Materials, 284-286: 905-908, 2005.

Biomechanical and histomorphometric study on the bone-screw interface of bioactive ceramic coated titanium screws. Jae Hyup Lee, Hyun-Seung Ryu, Dong-Soo Lee, Kug Sun Hong, Bong-Soon Chang, Choon-Ki Lee. Biomaterials, 26(16): 3249-3257, 2005, jun.

In vivo study of novel biodegradable and osteoconductive CaO-SiO2-B2O3 glass-ceramics. Jae Hyup Lee, Choon-Ki Lee, Bong-Soon Chang, Jun-Hyuk Seo, Hyun-Seung Ryu, Ki-Soo Park, Kug Sun Hong, and Hwan Kim. Journal of Biomedical and Materials Research A, 77(2): 362-369, 2006, may.

Scoliosis associated with syringomyelia: analysis of MRI and curve progression. Jin Sup Yeom, Choon-Ki Lee, Kun-Woo Park, Jae Hyup Lee, Dong-Ho Lee, Kyu-Chang Wang and Bong-Soon Chang, European spine journal, 16(10): 1629-1635, 2007, oct.

Effect of Intraoperative Position Used in Posterior Lumbar Interbody Fusion on the Maintenance of Lumbar Lordosis, Jae Hyup Lee, Ji-Ho Lee, Kang-Sup Yoon, Seung-Baik Kang, Chris H Jo, Journal of Neurosurgery: Spine, 8(3): 263-270, 2008, mar.

Surgical Treatment of Severe Angular Kyphosis with Myelopathy: Anterior and posterior approach with pedicle screw instrumentation. Kwang-Sup Song, Bong-Soon Chang, Jin S. Yeom, Jae Hyup Lee, Kun-Woo Park, Choon-Ki Lee. Spine, 33(11): 1229-1235, 2008, may.

Comparative study of Unilateral and Bilateral Cages with respect to Clinical Outcomes and Stability in Instrumented PLIF. Ji-Ho Lee, Jae Hyup Lee, Kang-Sup Yoon, Chris H Jo. Neurosurgery, 63(1): 109-113, 2008, jul.

Optimal configuration of arthroscopic sliding knots backed up with multiple half-hitches, Chris H Jo, Ji-Ho Lee, Seung-Baik Kang, Jae Hyup Lee, Hyuk-Soo Han, Tae Soo Bae, Kuiwon Choi, Changyang Lee, Myung Chul Lee, Kang-Sup Yoon, Knee Surgery, Sports Traumatology, Arthroscopy, 16(8): 787-793, 2008, aug.

Fetal mesenchymal stem cells derived from human umbilical cord sustain primitive characteristics during extensive expansion. Chris H. Jo, Ok-Su Kim, Eun-Young Park, Byoung Jae Kim, Ji-Ho Lee, Seung-Baik Kang, Jae Hyup Lee, Hyuk-Soo Han, Seung-Hwan Rhee, Kang-Sup Yoon, Cell and Tissue research, 334(3): 423-433, 2008, dec.

A 90-day subchronic toxicity study of beta-calcium pyrophosphate in rat. Jae Hyup Lee, Bong-Soon Chang, Hyun-Seung Ryu, Choon-Ki Lee, Drug and Chemical Toxicology, 32(3): 277-282, 2009.

Minimally Invasive Treatment of Painful Osteoporotic Vertebral Fractures. Jae Hyup Lee, Ji-Ho Lee, J Korean Med Assoc, 52(4): 382-392, 2009.

Inter- and Intra-observer Reliability on MRI for Lumbar Lateral Disc Herniation, Seong Wan Kim, Jin S. Yeom, Seong Kyu Park, Bong Soon Chang, Dong-Ho Lee, Jae Hyup Lee, Kun-Woo Park, Eun Seok Seo, Choon-Ki Lee, Clinics in Orthopedic Surgery, 1(1): 34-39, 2009, mar.

A Prospective Consecutive Study of Instrumented Posterolateral Lumbar Fusion Using Synthetic Hydroxyapatite (Bongros-HA) as a Bone Graft Extender. Jae Hyup Lee, Chang-Ju Hwang, Byung-Wook Song, Ki-Hyung Koo, Bong-Soon Chang, Choon-Ki Lee. Journal of Biomedical and Materials Research-A, 90(3): 804-810, 2009, sep.

Under-meniscal portal: an alternative portal for an easy access to the medial and lateral menisci, Chris HyunChul Jo, Kang-Sup Yoon, Ji-Ho Lee, Seung-Baik Kang, Jae Hyup Lee, Hyuk-Soo Han, Seung-Hwan Rhee, Knee Surgery Sports Traumatology Arthroscopy, 17(11): 1344-1346, 2009, nov.

Treatment of Bone Defects in Rabbit Tibiae using CaO-SiO2-P2O5-B2O3 Bioactive Ceramics: Radiological, Biomechanical, and Histological Evaluation, Ki Hyoung Koo, Changju Hwang, Jae Hyup Lee, Bong-Soon Chang, Choon-Ki Lee, Tissue Engineering and Regenerative Medicine, 6 (4-11): 811-818, 2009.

A 90-day intravenous administration toxicity study of CaO-SiO2-P2O5-B2O3 glass-ceramics (BGS-7) in rat, Jae Hyup Lee, Hyun-Seung Ryu, Jun-Hyuk Seo, Bong-Soon Chang, Choon-Ki Lee, Drug and Chemical Toxicology, 33(1), 38-47, 2010, jan.

Fusion rates and subsidence of morselized local bone grafted titainium cage in posterior lumbar interbody fusion- Quantitative analysis using three-Dimensional computed tomography scans, Jae Hyup Lee, Do-Whan Jeon, MD, Suk-Jae Lee, Bong-Soon Chang, Choon-Ki Lee, Spine, 35(15): 1460-1465, 2010, jul.

Outcome of spinal fusion for lumbar degenerative disease: a cross-sectional study in Korea., Chang-Bae Kong, Do-Whan Jeon, Bong-Soon Chang, Jae Hyup Lee, Kyung-Soo Suk, Jong-Beom Park, Spine, 35(15):1489-1494, 2010, jul.

Quantitantive comparison of novel CaO-SiO2-P2O5-B2O3 glass-ceramics (BGS-7) with hydroxyapatite as bone graft extender in rabbit ilium, Jae Hyup Lee, Ul-Oh Jeung, Do-Hwan Jeon, Bong-Soon Chang, Choon-Ki Lee, Tissue Engineering and Regenerative Medicine, 7(5): 540-547, 2010, sep.

Expression, purification and osteogenic bioactivity of recombinant human BMP-2 produced by Escherichia coli. Jae Hyup Lee, Soo-Jeong Jang, Tae-Young Koo, Chang Woo Suh, Eui Nam Lee, Kyung-Mee Lee, Hye Soo Lee, Hae-Ri Baek, Tissue Engineering and Regenerative Medicine, 8(1): 8-15, 2011.

Effects of bisphosphonate-treated bioactive ceramic grafts for the proliferation and osteoblastic differentiation of human bone marrow mesenchymal stem cells. Jae Hyup Lee, Kyung-Mee Lee, Soo-Jeong Jang, Hye Soo Lee, Hae-Ri Baek, Tissue Engineering and Regenerative Medicine, 8(1): 69-77, 2011.

Combined effects of porous hydroxyapatite and demineralized bone matrix on bone induction - In vitro and in vivo study using nude rat model. Jae Hyup Lee, Kyung-Mee Lee, Hae-Ri Baek, Soo-Jeong Jang, Ji-Ho Lee, Hyun-Seung Ryu, Biomedical Materials, 6(1):015008, 2011, feb.

Subsidence and nonunion after anterior cervical interbody fusion using a stand-alone olyetheretherketone (PEEK) cage. Jae Jun Yang, Chang Hun Yu, Bong-Soon Chang, Jin Sup Yeom, Jae Hyup Lee, Choon-Ki Lee, Clinics in orthopedic Surgery, 3(1): 16-23, 2011, mar.

Bioactive ceramic coating of cancellous screws improves the osseointegration in the cancellous bone, Jae Hyup Lee, Hwa Nam, Hyun-Seung Ryu, Jun-Hyuk Seo, Bong-Soon Chang, Choon-Ki Lee, Journal of Orthopaedic Science, 16(3): 291-297, 2011, may.

The impact of fentanyl matrix on pain and function in spinal disorder-related chronic pain -An open label trial in Korea-, Jae Hyup Lee, Sung-Cheol Yun, Jung-Gil Lee, Kyoung Hyo Choi, Dong-Soo Kim, Kook-Jin Chung, Ye-Soo Park, Whan Eoh, Asian Spine Journal, 5 (2): 91-99, 2011, jun.

Fusion rates of a morselized local bone graft in polyetheretherketone cages in posterior lumbar interbody fusion by quantitative analysis using consecutive three-dimensional computed tomography scans. Jae Hyup Lee, Ji-Ho Lee, Jae-Woo Park, Hye-Soo Lee, The Spine Journal, 11(7): 647-653, 2011, jul.

The efficacy of porous hydroxyapatite bone chip as an extender of local bone graft in posterior lumbar interbody fusion. Hyungmin Kim, Choon-Ki Lee, Jin-sup Yeom, Jae Hyup Lee, KH Lee, Bone-Soon Chang. European spine journal, 21(7): 1324-1330, 2011, jul.

The first clinical trial of beta-calcium pyrophosphate as a novel bone graft extender in instrumented posterolateral lumbar fusion, Jae Hyup Lee, Bone-Soon Chang,Ul-Oh Jeung, Kun-Woo Park, Min-Seok Kim, Choon-Ki Lee, Clinics in orthopedic Surgery, 3(3): 238-244, 2011, sep.

Does platelet-rich plasma accelerate recovery after rotator cuff repair? A prospective cohort study. Chris Hynchul Jo, Ji-Eun Kim, Kang-Sup Yoon, Ji-Ho Lee, Seung-Baik Kang, Jae Hyup Lee, Hyuk-Soo Han, Seung-Hwan Rhee, Soo Shin, Am J Sports Med, 39(10): 2082-2090, 2011, oct.

The effect of multiple channeling on the structural integrity of repaired rotator cuff. Jo CH, Yoon KS, Lee JH, Kang SB, Lee JH, Han HS, Rhee SH, Shin JS. Knee Surg Sports Traumatol Arthrosc. 19(12): 2098-2107, 2011, dec.

Comparative study of fusion rate induced by different dosages of Escherichia coli-derived recombinant human bone morphogenetic protein-2 using hydroxyapatite carrier. Jae Hyup Lee, Chang Hun Yu, Jae Jun Yang, Hae-Ri Baek, Kyung-Mee Lee, Tae-Young Koo, Bong-Soon Chang, Choon-Ki Lee, The Spine Journal, 12(3): 239-248, 2012, mar.

The effectiveness of poloxamer 407-based new anti-adhesive material in a laminectomy model in rats. Chang Hun Yu, Jae Hyup Lee, Hae-Ri Baek, Hwa Nam, European Spine Journal, 21(5): 971-979, 2012, may.

The insertional torque of a pedicle screw has a positive correlation with bone mineral density in posterior lumbar pedicle screw fixation. Jae Hyup Lee, Ji-Ho Lee, Jae Woo Park, Young Ho Shin, The Journal of Bone and Joint Surgery, Br, 94-B (1): 93-97, 2012, dec.

Effects of alendronate on lumbar posterolateral fusion using hydroxyapatite in rabbits. Ki-Hyeong Koo, Jae Hyup Lee, Bong-Soon Chang, Choon-Ki Lee, Artificial organs, 36(12): 1047-1055, 2012, dec.

Normal range of the inflammation related laboratory findings and predictors of the postoperative infection in spinal posterior fusion surgery. Ji-Ho Lee, Jae Hyup Lee, Ji-Beom Kim, Hyeong-Seok Lee, Do-Yoon Lee, Dong-Oh Lee. Clinics in Orthopedic Surgery, 4(4), 269-277, 2012, dec.

Evaluation of the efficacy of Escherichia coli-derived recombinant human bone morphogenetic protein-2 in a mini-pig spinal anterior interbody fusion model. Changju Hwang, Jae Hyup Lee, Hae-Ri Baek, Bong-Soon Chang, Choon-Ki Lee, The Journal of Bone and Joint Surgery, Br, 95-B(2): 217-223, 2013, feb.

In vitro and in vivo evaluation of the bioactivity of hydroxyapatite coated polyetheretherketone biocomposites created by cold spray technology. Jae Hyup Lee, Hae Lin Jang, Kyung Mee Lee, Hae-Ri Baek, Kyoungsuk Jin, Kug Sun Hong, Jun Hong Noh, Hyun-Kyung Lee. Acta biomaterialia, 9(4):6177-6187, 2013, apr.

The efficacy of carotid tubercle as an anatomical landmark for identification of cervical spinal level in the anterior cervical surgery: Comparison with preoperative C-arm fluoroscopy. Jae Hyup Lee, Ji-Ho Lee, Hyeong-Seok Lee, Do-Yoon Lee, Dong-Oh Lee. Clinics in Orthopedic Surgery, 5(2): 129-133, 2013, jun.

The efficacy of porous hydroxyapatite granule as a carrier of E.coli-derived recombinant human bone morphogenetic protein-2, Jae Hyup Lee, Hae-Ri Baek, Eui-Nam Lee, Kyung Mee Lee, Hyun-Kyung Lee, Tissue Engineering and Regenerative Medicine, 10(5): 279-285, 2013.

Asymmetry of the cross-sectional area of paravertebral and psoas muscle in patients with degenerative scoliosis. Hyoungmin Kim, Choon-Ki Lee, Jin S Yeom, Jae Hyup Lee, Jae Hwan Cho, Sank Ik Shin, Hui-Jong Lee, Bong-Soon Chang, European Spine Journal, 22(6): 1332-1338, 2013, jun.

Fabrication and Evaluation of Osteoblastic Differentiation of Human Mesenchymal Stem Cells on Novel CaO-SiO2-P2O5-B2O3 Glass-Ceramics, Jae Hyup Lee, Jun-Hyuk Seo, Kyung Mee Lee, Hyun-Seung Ryu, Hae-Ri Baek, Artificial Organs, 37(7): 637-647, 2013, jul.

In Vivo Evaluation of CaO-SiO2-P2O5-B2O3 Glass-ceramics Coating on Steinman Pin. Jae Hyup Lee, Kug Sun Hong, Hae-Ri Baek, Jun-Hyuk Seo, Kyung Mee Lee, Hyun-Seung Ryu, Hyun-Kyung Lee. Artificial Organs, 37(7): 656-662, 2013 jul.

Single-Crystal Apatite Nanowires Sheathed in Graphitic Shells: Synthesis, Characterization and Application, Namjo Jeong, Misun Cha, Yun Chang Park, Kyung Mee Lee, Jae Hyup Lee, Byong Chon Park, Junghoon Lee, ACS Nano, 7(7): 5711-5723, 2013, jul.

Effects of porous beta-tricalcium phosphate-based ceramics used as an E.coli-derived rhBMP-2 carrier for bone regeneration. Jae Hyup Lee, Mi Young Ryu, Hae-Ri Baek, Kyung Mee Lee, Jun-Hyuk Seo, Hyun-Kyung Lee, Hyun-Seung Ryu, Journal of Materials Science Materials in Medicine, 24(9): 2117-2127, 2013, sep.

The short-term effects of repetitive E.coli-derived rhBMP-2 administration through intravenous injection in rats. Jae Hyup Lee, Eui-Nam Lee, Sang Hyun Nam. Drug and Chemical Toxicology, 37(1), 40-47, 2014, jan.

Usefulness of prone cross-table lateral radiographs in vertebral compression fractures. Jae Hwan Cho, Sang Ik Shin, Jae Hyup Lee, Jin Sup Yeom, Bong-Soon Chang, Choon-Ki Lee, Clinics in Orthopedic Surgery, 5(3): 195-201, 2013, sep.

A comparison of dynamic views using plain radiographs and thin-section three-dimensional computed tomography in the evaluation of fusion after posterior lumbar interbody fusion surgery. Hyeong-Seok Lee, Jae Hyup Lee, Ji-Ho Lee, The Spine Journal, 13(10): 1200-1207, 2013, Oct.

Finite element modeling of stress distribution in intervertebral spacers of different surface geometries. Jae Hyup Lee, Baek Myong-Hyun, Young Eun Kim, Jun-Hyuk Seo, Dong Ryul Song, Hyun-Seung Ryu, Choon-Ki Lee, Bong-Soon Chang, Artificial Organs, 37(11), 1014-1020, 2013, nov.

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of the Extended-Release Tramadol HCl/Acetaminophen Fixed-Dose Combination Tablet for the Treatment of Chronic Lower Back Pain. Jae Hyup Lee, Chong-Suh Lee, on behalf of the Ultracet ER Study Group, Clinical Therapeutics, 35(11): 1830-1840, 2013, nov.

Fabrication and evaluation of porous beta tricalcium phosphate/hydroxyapatite (60/40) composite as a bone graft extender using rat. Jae Hyup Lee, Mi Young Ryu, Hae-Ri Baek, Kyung Mee Lee, Jun-Hyuk Seo, Hyun-Kyung Lee, The Scientific World Journal, 17, 481789, 9 pages, 2013 dec.

The effects of recombinant human bone morphogenetic protein-2-loaded tricalcium phosphate microsphere-hydrogel composite on the osseointegration of dental implants in minipigs. Jae Hyup Lee, Mi Young Ryu, Hae-Ri Baek, Hyun-Kyung Lee, Jun-Hyuk Seo, Kyung Mee Lee, A-Young Lee, Guang Bin Zheng, Bong-Soon Chang, Choon-Ki Lee, Artificial Organs, 38(2): 149-158, 2014, Feb.

Influence of Insurance Benefit Criteria on the Administration Rate of Osteoporosis Drugs in Postmenopausal Females. Jae Hyup Lee, Ye-Hyun Lee, Seoung-Hwan Moon, Yil-Seob Lee, The Prevalence of Osteoporotic Vertebral Compression Fractures in Korean Post Menoapusal Women Study Group, Clinics in Orthopedic Surgery, 6(1):56-61, 2014, Mar.

Negative Effect of Rapidly Resorbing Properties of Bioactive Glass-Ceramics as Bone Graft Substitute in a Rabbit Lumbar Fusion Model. Jae Hyup Lee, Hyun-Seung Ryu, Jun-Hyuk Seo, Do-Yoon Lee, Bong-Soon Chang, Choon-Ki Lee, Clinics in Orthopedic Surgery, Mar;6(1):87-95, 2014, mar.

Magnetic manipulation of bacterial magnetic nanoparticle-loaded neurospheres. Jaeha Shin, Kyung-Mee Lee, Jae Hyup Lee, Junghoon Lee, Misun Cha, Integrative Biololgy, 22, 6(5): 532-539, 2014 April.

Acute intravenous injection toxicity study of Escherichia coli-derived recombinant human bone morphogenetic protein-2 in rat. Jae Hyup Lee, Eui-Nam Lee, Bong-Soon Chang, Choon-Ki Lee, Asian Spine Journal, 8(2): 113-118, 2014 Apr.

How does chronic back pain influence quality of life in Koreans: a cross-sectional study. Yong Soo Choi, Dong Jun Kim, Kyu Yeol Lee, Ye Soo Park, Kyu Jung Cho, Jae Hyup Lee, Hyou Young Rhim, Byung Joon Shin, Asian Spine Journal, 8(3): 346-352, 2014, jun.

Association between Bone Mineral Density and Clinical Consequences: Cross-Sectional Study of Korean Postmenopausal Women in an Orthopaedic Outpatient Clinic. Jae Hyup Lee, Ye-Hyun Lee, Seong-Hwan Moon, TOP study group, Journal of Korean Medical Science, 29(8), 1152-1160, 2014 Aug.

Generation of an rhBMP-2-loaded beta-tricalcium phosphate/hydrogel composite and evaluation of its efficacy on peri-implant bone formation. Jae Hyup Lee, Mi-Young Ryu, Hae-Ri Baek, Jun-Hyuk Seo, Kyung Mee Lee, Ji-Ho Lee, Biomedical Materials, 9(5): 055002, 2014 Aug.

Fabrication of an rhBMP-2 loaded porous β-TCP microsphere-hyaluronic acid-based powder gel composite and evaluation of implant osseointegration. Jae Hyup Lee, Jungju Kim, Hae-Ri Baek, Kyung Mee Lee, Jun-Hyuk Seo, Hyun-Kyung Lee, A-Young Lee, Guang Bin Zheng, Bong-Soon Chang, Choon-Ki Lee, Journal of Materials Science Materials in Medicine, 25(9): 2141-2151, 2014 Sep.

Comparison of radiological and clinical results of ballon kyphoplasty according to anterior height loss in the osteoporotic vertebral fracture. Jae Hyup Lee, Dong-Oh Lee, Ji-Ho Lee, Heong-Seok Lee, The Spine Journal, 14(10): 2281-2289, 2014 Oct.

Posterolateral lumbar fusion using Escherichia coli-derived rhBMP-2/hydroxyapatite in the mini-pig. Chang-Bae Kong, Jae Hyup Lee, Hae-Ri Baek, Choon-Ki Lee, Bong-Soon Chang, The Spine Journal, 14(12): 2959-2967, 2014, Dec.

Effect of Graphitic Layers Encapsulating Single-Crystal Apatite Nanowire on the Osteogenesis of Human Mesenchymal Stem Cells. Namjo Jeong, Yun Chang Park, Kyung-Mee Lee, Jae Hyup Lee, Misun Cha, The Journal of Physical Chemistry B, 118(48): 13849-13858, 2014, Dec.

The effect of poloxamer 407-based hydrogel on the osteoinductivity of demineralized bone matrix. Jae Hyup Lee, Hae-Ri Baek, Kyung Mee Lee, Hyun-Kyung Lee, Seung Bin Im, Yong Sung Kim, Ji-Ho Lee, Bong-Soon Chang, Choon-Ki Lee, Clinics in Orthopedic Surgery, 6(4): 455-461, 2014, Dec.

Effects of lordotic angle of a cage on sagittal alignment and clinical outcome in one level posterior lumbar interbody fusion with pedicle screw fixation. Ji-Ho Lee, Dong-Oh Lee, Jae Hyup Lee, Hee Jong Shim, BioMed Research International, 523728, 6 pages, 2015, jan.

Enhanced osteoinductivity of recombinant human bone morphogenetic protein-2 in combination with epidermal growth factor in a rabbit tibial defect model. Jae Hyup Lee, Hae-Ri Baek, Kyung Mee Lee, Dong-Yoen Lee, A-Young Lee, Growth Factors, 33(1): 31-39, 2015, feb.

Synergistic induction of early stage of bone formation by combination of recombinant human bone morphogenetic protein-2 and epidermal growth factor. Jae Hyup Lee, Soo-Jeong Jang, Hae-Ri Baek, Kyung Mee Lee, Bong-Soon Chang, Choon-Ki Lee, Journal of Tissue Engineering and Regenerative Medicine, 9(4), 447-459, 2015 Apr.

The inhibitory effect of zoledronate on early-stage osteoinduction by recombinant human bone morphogenetic protein 2 in an osteoporosis model. Jae Hyup Lee, Hae-Ri Baek, Kyung Mee Lee, Guang Bin Zheng, Sung Joon Shin, Yuan Zhe Jin, Growh Factors, 33(3): 220-228, 2015, Jun.

Effects of ovariectomy and corticosteroid induced osteoporosis on the osteoinductivity of rhBMP-2 in a segmental long-bone defect model. Jae Hyup Lee, Hae-Ri Baek, Kyung-Mee Lee, Guang Bin Zheng, Sung Joon Shin, Hee-Jong Shim, Tissue Engineering A, 21(15-16):2262-2271, 2015, Aug.

The toxicological evaluation of repetitive 2- and 4-week intravenous injection of Activin A/BMP-2 chimera (AB204) into rats. Byung-Hak Yoon, Jae Hyup Lee, Kyuheum Na, Jongho Cho, Senyon Choe, Regulatory Toxicology and Pharmacology, 73(1): 1-8, 2015, Oct.

In Vitro and In Vivo Evaluation of Whitlockite Biocompatibility: Comparative Study with Hydroxyapatite and β-Tricalcium Phosphate. Hae Lin Jang, Guang Bin Zheng, Jungha Park, Hwan D. Kim, Hae-Ri Baek, Hye Kyoung Lee, Keunho Lee, Heung Nam Han, Choon-Ki Lee, Nathaniel S. Hwang, Jae Hyup Lee, Ki Tae Nam, Advanced Healthcare Materials, 5(1), 128-136, 2016, Jan.

The effects of a single intravenous injection of novel activin A/BMP-2 (AB204) on toxicity and the respiratory and central nervous systems. Byung-Hak Yoon, Jae Hyup Lee, Kyuheum Na, Chihoon Ahn, Jongho Cho, Hyun Chan Ahn, Jungyoun Choi, Hyosun Oh, Byong Moon Kim, Senyon Choe. Drug and Chemical Toxicology, 39(3): 284-289, 2016.

Prospective, randomized, double-blinded, double-dummy and multicenter phase IV clinical study comparing the efficacy and safety of PG201 (Layla) and SKI306X in patients with osteoarthritis. Chul-Won Ha, Yong-Beom Park, Byung-Woo Min, Seung-Beom Han, Jae Hyup Lee, Ye-Yeon Won, Ye-Soo Park, Journal of Ethnopharmacology, 181: 1-7, 2016, apr.

Comparative study of the efficacy of limaprost and pregabalin as single agents and in combination for the treatment of lumbar spinal stenosis: a prospective, double blind, randomized controlled non-inferiority trial. Ho-Joong Kim, Jin Hyok Kim, Ye Soo Park, Kyung Soo Suk, Jae Hyup Lee, Moon Soo Park, Seong-Hwan Moon, The Spine Journal, 16(6): 756-763, 2016, jun.

Effects of brace to osteoporotic vertebral fracture: a meta-analysis. Jin YuanZhe, Jae Hyup Lee, Journal of Korean Medial Science, 31(10): 1641-1649, 2016, oct.

Comparison of fusion rate and clinical results between CaO-SiO2-P2O5-B2O3 bioactive glass ceramics spacer with titanium cages in posterior lumbar interbody fusion. Jae Hyup Lee, Jae Jun Yang, Hee-Jong Shim, Ki-Hyoung Koo, Jeehyoung Kim, Choon-Ki Lee, Bong-Soon Chang. The Spine Journal, 16(11):1367-1376, 2016, nov.

Anti-adhesive effect of poloxamer-based thermos-sensitive sol-gel in rabbit laminectomy model. Sung Joon Shin, Jae Hyup Lee, Jungwon So, Kyungdan Min, Journal of Materials Science and Materials in Medicine, 27(11): 162-170, 2016, nov.

Clinical usefulness of long-term application of fentanyl matrix in chronic non-cancer pain: improvement of pain and physical and emotional functions. Jaewon Lee, Joon Shik Yoon, Jae Hyup Lee, So-Hak Chung, Kyu-Yeol Lee, Young Yul Kim, Jong Moon Kim, Min Ho Kong, Ung Gu Kang, Ye-Soo Park, Clinics in Orthopedic Surgery, 8(4):465-474, 2016, dec.

A Nationwide Retrospective Study of Opioid Management Patterns in 2,468 Patients with Spinal Pain in Korea. Sung-Soo Chung, Chun-Kun Park, Kyu-Jung Cho, Kyoung Hyo Choi,Jin-Hyok Kim, Sung-Bum Kim, Sung-Uk Kuh, Jae Chul Lee, Jae Hyup Lee, Kyu-Yeol Lee, Sun-Ho Lee, Seong-Hwan Moon, Si-Young Park, Jae Hang Shim, Byung-Chul Son, Myung Ha Yoon, Hye-Jeong Park. Asian Spine Journal, 10(6):1122-1131, 2016, dec.

Treatment outcomes for patients with failed back surgery. Jae Hwan Cho, Jae Hyup Lee, Kwang Sup Song, Jae-Young Hong, Yoon-Suk Joo, Dong-Ho Lee, Chang Ju Hwang, Choon Sung Lee. Pain Physician, 20(1):E29-E43, 2017, jan.

Effect of Drugs Associated With Bleeding Tendency on the Complications and Outcomes of Transforaminal Epidural Steroid Injection. Tae Keun Park, Sung Joon Shin, Jae Hyup Lee, Clinical Spine Surgery, 30(2):E104-E110, 2017, mar.

Cold-spray coating of hydroxyapatite on a three-dimensional polyetheretherketone implant and its biocompatibility evaluated by in vitro and in vivo minipig model. Jae Hyup Lee, Hae Lin Jang, Kyung Mee Lee, Hae-Ri Baek, Kyoungsuk Jin, Jun Hong Noh, Journal of Biomedical Materials Research B, 105(3): 647-657, 2017, apr.

The correlation between cage subsidence, bone mineral density, and clinical results in posterior lumbar interbody fusion. Kyu Won Oh, Jae Hyup Lee, Ji-Ho Lee, Do-Yoon Lee, Hee Jong Shim, Clinical Spine Surgery, 30(6), E683-E689, 2017, jul.

Influence of hydroxyapatite stick on pedicle screw fixation in degenerative lumbar spine Biomechanical and radiologic study. Sung Joon Shin, Ji-Ho Lee, Jae Hyup Lee, Clinical Spine Surgery, 30(6), E819-E826, 2017, jul.

Surgical techniques and clinical evidence of vertebroplasty and kyphoplasty for osteoporotic vertebral fractures. Jae Hyup Lee, Ji-Ho Lee, Yuanzhe Jin, Osteoporosis and Sarcopenia, 3(2): 82-89, 2017

Comparison of the osteogenesis and fusion rates between activin a / BMP-2 chimera (AB204) and rhBMP-2 in a beagle's posterolateral lumbar spine model. Guang Bin Zheng, Byung-Hak Yoon, Jae Hyup Lee, The Spine Journal, 17(10):1529-1536, 2017.

Efficacy of Escherichia coli-derived recombinant human bone morphogenetic protein-2 in posterolateral lumbar fusion: an open, active-controlled, randomized, multicenter trial. Jae Hwan Cho, Jae Hyup Lee, Jin Sup Yeom, Bong-Soon Chang, Jae Jun Yang, Ki Hyoung Koo, Chang Ju Hwang, Kwang Bok Lee, Ho-Joong Kim, MD, Choon-Ki Lee, Hyoungmin Kim, Kyung-Soo Suk, Woo Dong Nam, Jumi Han, The Spine Journal, 17(12):1866-1874, 2017

Efficacy and safety of buprenorphine transdermal patch versus oral tramadol/acetaminophen in patients with persistent post-operative pain after spinal surgery, Jae Hyup Lee, Jin-Hyok Kim, Jin-Hwan Kim, Hak-Sun Kim, Woo-Kie Min, Ye-Soo Park, Kyu-Yeol Lee, Jung-Hee Lee, Pain Research and Management, 20171494, 11 pages, 2017

Neuropathic pain after spinal surgery, Jae Hwan Cho, Jae Hyup Lee, Kwang-Sup Song, Jae-Young Hong, Asian Spine Journal, 11(4), 642-652, 2017, aug.

An Updated Overview of Low Back Pain Management in Primary Care, Jae-Young Hong, Kwang-Sup Song, Jae Hwan Cho, Jae Hyup Lee. Asian Spine Journal, 11(4), 653-660, 2017, aug.

Neuropathic Pain Related with Spinal Disorders: A Systematic Review, Kwang-Sup Song, Jae Hwan Cho, Jae-Young Hong, Jae Hyup Lee, Hyun Kang, Dae-Woong Ham, Hyun-Jun Ryu. Asian Spine Journal, 11(4), 661-674, 2017, aug.

In vitro and in vivo evaluation of osteoinductivity and bone fusion ability of an Activin A/BMP2 chimera (AB204): a comparison study between AB204 and rhBMP-2, Guang Bin Zheng, Jae Hyup Lee, Yuan-Zhe Jin, Growth Factors, 2017, 35(6), 249-258

The cardiovascular effect of single injection and toxicologic effects of repetitive 2-week intravenous administration of Activin A/BMP-2 chimera in Beagle dog. Jae Hyup Lee, Senyon Choe, Shihuan Han, Cardiovascular toxicology, 18(1), 76-83, 2018.

Analgesic Efficacy and Safety of Prolonged-Release Oxycodone/Naloxone in Korean Patients with Chronic Pain from Spinal Disorders. Chang Ju Hwang, Sung Soo Chung, Kyu-Yeol Lee, Jae Hyup Lee, Seong-Hwan Moon, Jin-Hyok Kim, Kyu-Jung Cho, Jae-Sung Ahn, Dong-Soo Kim, Ye-Soo Park, Hye-Jeong Park, Clinics in Orthopedic Surgery, 10(1): 33-40, 2018.

Effects of epidural steroid injections to bone mineral density and anti-osteoporotic medications, Seon yoon Nah, Jae Hyup Lee, Ji-Ho Lee, Pain Physician, 2018, 21(4), E435-E447.

Positive Effects of Bisphosphonates on Osteogenic Differentiation in Patient-Derived Mesenchymal Stem Cells for the Treatment of Osteoporosis, Misun Cha, Kyung Mee Lee, Jae Hyup Lee, Tissue Engineering and Regenerative Medicine, 2018, 15(4), 467-475.

A rat osteoporosis model induced by ovariectomy and glucocorticoid, Jae Hyup Lee, Yuanzhe Jin, Journal of Biological Regulators and Homeostatic Agents, 2018, 32(4), 769-780.

Mesenchymal Stem Cell Therapy for Bone Regeneration, Yuan-Zhe Jin, Jae Hyup Lee, Clinics in Orthopedic Surgery 2018, 10(3), 271-278.

Recombinant human bone morphogenetic protein-2 loaded porous β-tricalcium phosphate microsphere-hyaluronic acid composites promoted osseointegration around titanium implants. Jae Hyup Lee, Yuanzhe Jin, International Journal of Polymeric Materials and Polymeric Biomaterials, 2019, 68(7), 368-374

Assessment of patient-reported outcomes (PROs): treatment satisfaction, medication adherence, and quality of life (QoL) and the associated factors in postmenopausal osteoporosis (PMO) patients in Korea, Dong Won Byun, Seong-Hwan Moon, Tak Kim, Hae-Hyeog Lee, Hyoung Moo Park, Moo-Il Kang, Yong-Chan Ha, Ho-Yeon Chung, Byung-Koo Yoon, Tae-Young Kim, Soo Uk Chae, Chan Soo Shin, Kyu-Hyun Yang, Jae Hyup Lee, Jae Suk Chang, Sung Hoon Kim, In Joo Kim, Jung-Min Koh, Jung Hwa Jung, Kyong Wook Yi, Jeong Joon Yoo, Dong Jin Chung, Young-Kyun Lee, Hyun-Koo Yoon, Seongbin Hong, Deog-Yoon Kim, Ki Hyun Baek, Hyun-Joo Kim, Young-Joo Kim, Seongsik Kang, Yong-Ki Min, Journal of Bone and Mineral Metabolism, 2018, E-pub ahead of print

Gabapentin versus Transdermal Fentanyl Matrix for the Alleviation of Chronic Neuropathic Pain of Radicular Origin: A Randomized Blind Multicentered Parallel-Group Noninferiority Trial. Chang Ju Hwang, Jae Hyup Lee, Jung-Hoon Kim, Sang Hyuk Min, Kun-Woo Park, Hyoung-Yeon Seo, Kwang-Sup Song. Pain Research and Management, 2019, 4905013, 9 pages

The toxicological effect of 4-week repeated intravenous injection of Activin A/BMP-2 chimera and 2-week recovery study in Beagle dog, Shi Huan Han, Jae Hyup Lee, Senyon Choe, Bin Zheng, Drug and Chemical Toxicology, 2019, E-pub

Preparation of beta-tricalcium phosphate microsphere-hyaluronic acid-based powder gel composite as a carrier for rhBMP-2 injection and evaluation using long bone segmental defect model, Shi Huan Han, Su Hyun Jung, Jae Hyup Lee, Journal of Biomaterials Science, Polymer Edition, 2019, E-pub

Escherichia coli BMP-2 showed comparable osteoinductivity with Chinese hamster ovary derived BMP-2 with demineralized bone matrix as carrier, Yuan-Zhe Jin, Guang-Bin Zheng, Jae Hyup Lee, Growth Factors, 2019, E-pub

저서

참살이 의학(청소년기 척추측만증), 서울대학교 출판부(2006)
골절학 3판(소아 척추 골절), 군자출판사(2008)
척추외과학 3판(척추외과 영역에서의 생체재료), 최신의학사(2011)
학생을 위한 정형외과학(골이식술 및 골대체제, 척추전방전위증), 군자출판사(2013)
정형외과학(골이식), 최신의학사(2013)
척추외과학 3판, 대표저자 석세일, 생체재료 (chapter 저자), 최신의학사, 2017년
골절학, 저자 대한골절학회, Section 3 척추 editor, 흉요추골절 chapter 저자, 범문사, 2018년

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